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Items: 1 to 50 of 115

1.

In vitro cytotoxicity of cabazitaxel in adrenocortical carcinoma cell lines and human adrenocortical carcinoma primary cell cultures.

Fragni M, Palma Lopez LP, Rossini E, Abate A, Cosentini D, Salvi V, Vezzoli S, Poliani PL, Bosisio D, Hantel C, Tiberio GAM, Grisanti S, Memo M, Terzolo M, Berruti A, Sigala S.

Mol Cell Endocrinol. 2019 Sep 16;498:110585. doi: 10.1016/j.mce.2019.110585. [Epub ahead of print]

PMID:
31536779
2.

Human iPSC modeling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.

Benzoni P, Campostrini G, Landi S, Bertini V, Marchina E, Iascone M, Ahlberg G, Olesen MS, Crescini E, Mora C, Bisleri G, Muneretto C, Ronca R, Presta M, Poliani PL, Piovani G, Verardi R, Pasquale ED, Consiglio A, Raya A, Torre E, Lodrini AM, Milanesi R, Rocchetti M, Baruscotti M, DiFrancesco D, Memo M, Barbuti A, Dell'Era P.

Cardiovasc Res. 2019 Aug 28. pii: cvz217. doi: 10.1093/cvr/cvz217. [Epub ahead of print]

PMID:
31504264
3.

High-Definition 3-Dimensional Exoscope for 5-ALA Glioma Surgery: 3-Dimensional Operative Video.

Doglietto F, Belotti F, Panciani P, Poliani PL, Fontanella MM.

Oper Neurosurg (Hagerstown). 2019 Jun 7. pii: opz139. doi: 10.1093/ons/opz139. [Epub ahead of print]

PMID:
31173153
4.

Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices.

Daley SR, Koay HF, Dobbs K, Bosticardo M, Wirasinha RC, Pala F, Castagnoli R, Rowe JH, Ott de Bruin LM, Keles S, Lee YN, Somech R, Holland SM, Delmonte OM, Draper D, Maxwell S, Niemela J, Stoddard J, Rosenzweig SD, Poliani PL, Capo V, Villa A, Godfrey DI, Notarangelo LD.

J Allergy Clin Immunol. 2019 Jul;144(1):333-336. doi: 10.1016/j.jaci.2019.03.022. Epub 2019 Apr 30. No abstract available.

PMID:
31053347
5.

DNA threads released by activated CD4+ T lymphocytes provide autocrine costimulation.

Costanza M, Poliani PL, Portararo P, Cappetti B, Musio S, Pagani F, Steinman L, Colombo MP, Pedotti R, Sangaletti S.

Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):8985-8994. doi: 10.1073/pnas.1822013116. Epub 2019 Apr 15.

PMID:
30988194
6.

Thymic Epithelium Abnormalities in DiGeorge and Down Syndrome Patients Contribute to Dysregulation in T Cell Development.

Marcovecchio GE, Bortolomai I, Ferrua F, Fontana E, Imberti L, Conforti E, Amodio D, Bergante S, Macchiarulo G, D'Oria V, Conti F, Di Cesare S, Fousteri G, Carotti A, Giamberti A, Poliani PL, Notarangelo LD, Cancrini C, Villa A, Bosticardo M.

Front Immunol. 2019 Mar 15;10:447. doi: 10.3389/fimmu.2019.00447. eCollection 2019.

7.

Neuroendocrine breast carcinoma metastasis to the brain.

Zanin L, Poliani PL, Liserre R, Panciani PP.

BMJ Case Rep. 2019 Mar 7;12(3). pii: e228846. doi: 10.1136/bcr-2018-228846. No abstract available.

PMID:
30850573
8.

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1.

Narayanan A, Gagliardi F, Gallotti AL, Mazzoleni S, Cominelli M, Fagnocchi L, Pala M, Piras IS, Zordan P, Moretta N, Tratta E, Brugnara G, Altabella L, Bozzuto G, Gorombei P, Molinari A, Padua RA, Bulfone A, Politi LS, Falini A, Castellano A, Mortini P, Zippo A, Poliani PL, Galli R.

Cell Death Differ. 2019 Sep;26(9):1813-1831. doi: 10.1038/s41418-018-0248-7. Epub 2018 Dec 11.

9.

Altered function of the glutamate-aspartate transporter GLAST, a potential therapeutic target in glioblastoma.

Corbetta C, Di Ianni N, Bruzzone MG, Patanè M, Pollo B, Cantini G, Cominelli M, Zucca I, Pisati F, Poliani PL, Finocchiaro G, Pellegatta S.

Int J Cancer. 2019 May 15;144(10):2539-2554. doi: 10.1002/ijc.31985. Epub 2019 Jan 5.

PMID:
30418668
10.

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development.

Ott de Bruin LM, Bosticardo M, Barbieri A, Lin SG, Rowe JH, Poliani PL, Ching K, Eriksson D, Landegren N, Kämpe O, Manis JP, Notarangelo LD.

Blood. 2018 Jul 19;132(3):281-292. doi: 10.1182/blood-2017-12-820985. Epub 2018 May 9.

11.

18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis.

Belloli S, Zanotti L, Murtaj V, Mazzon C, Di Grigoli G, Monterisi C, Masiello V, Iaccarino L, Cappelli A, Poliani PL, Politi LS, Moresco RM.

J Neuroinflammation. 2018 Feb 5;15(1):33. doi: 10.1186/s12974-017-1044-x.

12.

Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt.

Zordan P, Cominelli M, Cascino F, Tratta E, Poliani PL, Galli R.

J Clin Invest. 2018 Apr 2;128(4):1688-1706. doi: 10.1172/JCI96342. Epub 2018 Mar 12.

13.

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains.

Longhena F, Faustini G, Varanita T, Zaltieri M, Porrini V, Tessari I, Poliani PL, Missale C, Borroni B, Padovani A, Bubacco L, Pizzi M, Spano P, Bellucci A.

Brain Pathol. 2018 Nov;28(6):875-888. doi: 10.1111/bpa.12587. Epub 2018 Feb 23.

PMID:
29330884
14.

Cavin-2 is a specific marker for detection of well-differentiated liposarcoma.

Codenotti S, Vezzoli M, Poliani PL, Cominelli M, Monti E, Fanzani A.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):660-665. doi: 10.1016/j.bbrc.2017.08.135. Epub 2017 Sep 1.

PMID:
28865960
15.

Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin.

Musio S, Costanza M, Poliani PL, Fontana E, Cominelli M, Abolafio G, Steinman L, Pedotti R.

Neurol Neuroimmunol Neuroinflamm. 2017 Apr 14;4(3):e342. doi: 10.1212/NXI.0000000000000342. eCollection 2017 May.

16.

In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.

Castiello MC, Pala F, Sereni L, Draghici E, Inverso D, Sauer AV, Schena F, Fontana E, Radaelli E, Uva P, Cervantes-Luevano KE, Benvenuti F, Poliani PL, Iannacone M, Traggiai E, Villa A, Bosticardo M.

Front Immunol. 2017 May 2;8:490. doi: 10.3389/fimmu.2017.00490. eCollection 2017.

17.

Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.

Platt CD, Chou J, Houlihan P, Badran YR, Kumar L, Bainter W, Poliani PL, Perez CJ, Dent SYR, Clapham DE, Benavides F, Geha RS.

J Allergy Clin Immunol. 2017 Dec;140(6):1651-1659.e1. doi: 10.1016/j.jaci.2016.12.974. Epub 2017 Feb 10.

18.

EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay.

Volpi S, Yamazaki Y, Brauer PM, van Rooijen E, Hayashida A, Slavotinek A, Sun Kuehn H, Di Rocco M, Rivolta C, Bortolomai I, Du L, Felgentreff K, Ott de Bruin L, Hayashida K, Freedman G, Marcovecchio GE, Capuder K, Rath P, Luche N, Hagedorn EJ, Buoncompagni A, Royer-Bertrand B, Giliani S, Poliani PL, Imberti L, Dobbs K, Poulain FE, Martini A, Manis J, Linhardt RJ, Bosticardo M, Rosenzweig SD, Lee H, Puck JM, Zúñiga-Pflücker JC, Zon L, Park PW, Superti-Furga A, Notarangelo LD.

J Exp Med. 2017 Mar 6;214(3):623-637. doi: 10.1084/jem.20161525. Epub 2017 Feb 1.

19.

Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients.

Sauer AV, Hernandez RJ, Fumagalli F, Bianchi V, Poliani PL, Dallatomasina C, Riboni E, Politi LS, Tabucchi A, Carlucci F, Casiraghi M, Carriglio N, Cominelli M, Forcellini CA, Barzaghi F, Ferrua F, Minicucci F, Medaglini S, Leocani L, la Marca G, Notarangelo LD, Azzari C, Comi G, Baldoli C, Canale S, Sessa M, D'Adamo P, Aiuti A.

Sci Rep. 2017 Jan 11;7:40136. doi: 10.1038/srep40136.

20.

A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth.

Mayrhofer M, Gourain V, Reischl M, Affaticati P, Jenett A, Joly JS, Benelli M, Demichelis F, Poliani PL, Sieger D, Mione M.

Dis Model Mech. 2017 Jan 1;10(1):15-28. doi: 10.1242/dmm.026500. Epub 2016 Nov 24.

21.

Caveolin-1, Caveolin-2 and Cavin-1 are strong predictors of adipogenic differentiation in human tumors and cell lines of liposarcoma.

Codenotti S, Vezzoli M, Poliani PL, Cominelli M, Bono F, Kabbout H, Faggi F, Chiarelli N, Colombi M, Zanella I, Biasiotto G, Montanelli A, Caimi L, Monti E, Fanzani A.

Eur J Cell Biol. 2016 Aug;95(8):252-64. doi: 10.1016/j.ejcb.2016.04.005. Epub 2016 May 4.

PMID:
27168348
22.

MET inhibition overcomes radiation resistance of glioblastoma stem-like cells.

De Bacco F, D'Ambrosio A, Casanova E, Orzan F, Neggia R, Albano R, Verginelli F, Cominelli M, Poliani PL, Luraghi P, Reato G, Pellegatta S, Finocchiaro G, Perera T, Garibaldi E, Gabriele P, Comoglio PM, Boccaccio C.

EMBO Mol Med. 2016 May 2;8(5):550-68. doi: 10.15252/emmm.201505890. Print 2016 May.

23.

Pattern of relapse of glioblastoma multiforme treated with radical radio-chemotherapy: Could a margin reduction be proposed?

Buglione M, Pedretti S, Poliani PL, Liserre R, Gipponi S, Spena G, Borghetti P, Pegurri L, Saiani F, Spiazzi L, Tesini G, Uccelli C, Triggiani L, Magrini SM.

J Neurooncol. 2016 Jun;128(2):303-12. doi: 10.1007/s11060-016-2112-2. Epub 2016 Mar 30.

PMID:
27025858
24.

Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.

Rigoni R, Fontana E, Guglielmetti S, Fosso B, D'Erchia AM, Maina V, Taverniti V, Castiello MC, Mantero S, Pacchiana G, Musio S, Pedotti R, Selmi C, Mora JR, Pesole G, Vezzoni P, Poliani PL, Grassi F, Villa A, Cassani B.

J Exp Med. 2016 Mar 7;213(3):355-75. doi: 10.1084/jem.20151116. Epub 2016 Feb 29.

25.

CCRL2 regulates M1/M2 polarization during EAE recovery phase.

Mazzon C, Zanotti L, Wang L, Del Prete A, Fontana E, Salvi V, Poliani PL, Sozzani S.

J Leukoc Biol. 2016 Jun;99(6):1027-33. doi: 10.1189/jlb.3MA0915-444RR. Epub 2016 Jan 7.

PMID:
26744451
26.

Constitutional de novo deletion of the FBXW7 gene in a patient with focal segmental glomerulosclerosis and multiple primitive tumors.

Roversi G, Picinelli C, Bestetti I, Crippa M, Perotti D, Ciceri S, Saccheri F, Collini P, Poliani PL, Catania S, Peissel B, Pagni F, Russo S, Peterlongo P, Manoukian S, Finelli P.

Sci Rep. 2015 Oct 20;5:15454. doi: 10.1038/srep15454.

27.

MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line.

Faggi F, Codenotti S, Poliani PL, Cominelli M, Chiarelli N, Colombi M, Vezzoli M, Monti E, Bono F, Tulipano G, Fiorentini C, Zanola A, Lo HP, Parton RG, Keller C, Fanzani A.

PLoS One. 2015 Jun 18;10(6):e0130287. doi: 10.1371/journal.pone.0130287. eCollection 2015.

28.

The treatment of patients with 1-3 brain metastases: is there a place for whole brain radiotherapy alone, yet? A retrospective analysis.

Buglione M, Pedretti S, Gipponi S, Buttolo L, Panciani P, Poliani PL, Liserre R, Borghetti P, Pegurri L, Costa L, Triggiani L, Pasinetti N, Ghirardelli P, Pandini S, Padovani A, Magrini SM; Neuro-Oncology Group, Spedali Civili Hospital and Brescia University.

Radiol Med. 2015 Dec;120(12):1146-52. doi: 10.1007/s11547-015-0542-0. Epub 2015 Apr 28.

PMID:
25917339
29.

TREM2 sustains microglial expansion during aging and response to demyelination.

Poliani PL, Wang Y, Fontana E, Robinette ML, Yamanishi Y, Gilfillan S, Colonna M.

J Clin Invest. 2015 May;125(5):2161-70. doi: 10.1172/JCI77983. Epub 2015 Apr 20.

30.

Critical role for prokineticin 2 in CNS autoimmunity.

Abou-Hamdan M, Costanza M, Fontana E, Di Dario M, Musio S, Congiu C, Onnis V, Lattanzi R, Radaelli M, Martinelli V, Salvadori S, Negri L, Poliani PL, Farina C, Balboni G, Steinman L, Pedotti R.

Neurol Neuroimmunol Neuroinflamm. 2015 Apr 9;2(3):e95. doi: 10.1212/NXI.0000000000000095. eCollection 2015 Jun.

31.

IL-10 critically modulates B cell responsiveness in Rankl-/- mice.

Marrella V, Lo Iacono N, Fontana E, Sobacchi C, Sic H, Schena F, Sereni L, Castiello MC, Poliani PL, Vezzoni P, Cassani B, Traggiai E, Villa A.

J Immunol. 2015 May 1;194(9):4144-53. doi: 10.4049/jimmunol.1401977. Epub 2015 Mar 30.

32.

Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.

Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A.

Lab Invest. 2015 Jun;95(6):585-602. doi: 10.1038/labinvest.2015.45. Epub 2015 Mar 30.

33.

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide.

Cominelli M, Grisanti S, Mazzoleni S, Branca C, Buttolo L, Furlan D, Liserre B, Bonetti MF, Medicina D, Pellegrini V, Buglione M, Liserre R, Pellegatta S, Finocchiaro G, Dalerba P, Facchetti F, Pizzi M, Galli R, Poliani PL.

J Natl Cancer Inst. 2015 Mar 3;107(5). pii: djv041. doi: 10.1093/jnci/djv041. Print 2015 May.

PMID:
25739547
34.

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression.

Hemmesi K, Squadrito ML, Mestdagh P, Conti V, Cominelli M, Piras IS, Sergi LS, Piccinin S, Maestro R, Poliani PL, Speleman F, De Palma M, Galli R.

Stem Cells. 2015 May;33(5):1377-89. doi: 10.1002/stem.1958.

35.

Reply: To PMID 24332219.

van Til NP, Cortes P, Danos O, Cassani B, Poliani PL, Villa A, Wagemaker G.

J Allergy Clin Immunol. 2014 Jul;134(1):243-4. doi: 10.1016/j.jaci.2014.04.032. Epub 2014 Jun 26. No abstract available.

PMID:
25117804
36.

Rag defects and thymic stroma: lessons from animal models.

Marrella V, Poliani PL, Notarangelo LD, Grassi F, Villa A.

Front Immunol. 2014 Jun 2;5:259. doi: 10.3389/fimmu.2014.00259. eCollection 2014. Review. Erratum in: Front Immunol. 2014;5:407. Grassi, Fabio [added].

37.

Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function.

Kumar L, Chou J, Yee CS, Borzutzky A, Vollmann EH, von Andrian UH, Park SY, Hollander G, Manis JP, Poliani PL, Geha RS.

J Exp Med. 2014 May 5;211(5):929-42. doi: 10.1084/jem.20131379. Epub 2014 Apr 21.

38.

Development of central nervous system autoimmunity is impaired in the absence of Wiskott-Aldrich syndrome protein.

Bosticardo M, Musio S, Fontana E, Angiari S, Draghici E, Constantin G, Poliani PL, Pedotti R, Villa A.

PLoS One. 2014 Jan 23;9(1):e86942. doi: 10.1371/journal.pone.0086942. eCollection 2014.

39.

Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma.

Faggi F, Mitola S, Sorci G, Riuzzi F, Donato R, Codenotti S, Poliani PL, Cominelli M, Vescovi R, Rossi S, Calza S, Colombi M, Penna F, Costelli P, Perini I, Sampaolesi M, Monti E, Fanzani A.

PLoS One. 2014 Jan 10;9(1):e84618. doi: 10.1371/journal.pone.0084618. eCollection 2014.

40.

Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome.

van Til NP, Sarwari R, Visser TP, Hauer J, Lagresle-Peyrou C, van der Velden G, Malshetty V, Cortes P, Jollet A, Danos O, Cassani B, Zhang F, Thrasher AJ, Fontana E, Poliani PL, Cavazzana M, Verstegen MM, Villa A, Wagemaker G.

J Allergy Clin Immunol. 2014 Apr;133(4):1116-23. doi: 10.1016/j.jaci.2013.10.009. Epub 2013 Dec 9.

PMID:
24332219
41.

Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration.

Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, Del Prete A, Sozzani S, Vezzoni P, Poliani PL, Villa A.

J Leukoc Biol. 2013 Dec;94(6):1221-30. doi: 10.1189/jlb.0713365. Epub 2013 Sep 19.

PMID:
24052573
42.

Inhibition of angiogenesis by β-galactosylceramidase deficiency in globoid cell leukodystrophy.

Belleri M, Ronca R, Coltrini D, Nico B, Ribatti D, Poliani PL, Giacomini A, Alessi P, Marchesini S, Santos MB, Bongarzone ER, Presta M.

Brain. 2013 Sep;136(Pt 9):2859-75. doi: 10.1093/brain/awt215.

43.

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration.

Frattini V, Pisati F, Speranza MC, Poliani PL, Frigé G, Cantini G, Kapetis D, Cominelli M, Rossi A, Finocchiaro G, Pellegatta S.

Oncotarget. 2012 Sep 22;3(10):1146-57. Print 2012 Oct.

44.

Exacerbation of experimental autoimmune encephalomyelitis by passive transfer of IgG antibodies from a multiple sclerosis patient responsive to immunoadsorption.

Pedotti R, Musio S, Scabeni S, Farina C, Poliani PL, Colombo E, Costanza M, Berzi A, Castellucci F, Ciusani E, Confalonieri P, Hemmer B, Mantegazza R, Antozzi C.

J Neuroimmunol. 2013 Sep 15;262(1-2):19-26. doi: 10.1016/j.jneuroim.2013.05.010. Epub 2013 Jun 13.

PMID:
23768729
45.

Timing of mTOR activation affects tuberous sclerosis complex neuropathology in mouse models.

Magri L, Cominelli M, Cambiaghi M, Cursi M, Leocani L, Minicucci F, Poliani PL, Galli R.

Dis Model Mech. 2013 Sep;6(5):1185-97. doi: 10.1242/dmm.012096. Epub 2013 Jun 5.

46.

Glutamine synthetase expression as a valuable marker of epilepsy and longer survival in newly diagnosed glioblastoma multiforme.

Rosati A, Poliani PL, Todeschini A, Cominelli M, Medicina D, Cenzato M, Simoncini EL, Magrini SM, Buglione M, Grisanti S, Padovani A.

Neuro Oncol. 2013 May;15(5):618-25. doi: 10.1093/neuonc/nos338. Epub 2013 Feb 14.

47.

ζ Chain-associated protein of 70 kDa (ZAP70) deficiency in human subjects is associated with abnormalities of thymic stromal cells: Implications for T-cell tolerance.

Poliani PL, Fontana E, Roifman CM, Notarangelo LD.

J Allergy Clin Immunol. 2013 Feb;131(2):597-600.e1-2. doi: 10.1016/j.jaci.2012.11.002. Epub 2012 Dec 14. No abstract available.

PMID:
23245794
48.

High doses of cobalt induce optic and auditory neuropathy.

Apostoli P, Catalani S, Zaghini A, Mariotti A, Poliani PL, Vielmi V, Semeraro F, Duse S, Porzionato A, Macchi V, Padovani A, Rizzetti MC, De Caro R.

Exp Toxicol Pathol. 2013 Sep;65(6):719-27. doi: 10.1016/j.etp.2012.09.006. Epub 2012 Oct 12.

PMID:
23069009
49.

Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO.

Lo Iacono N, Blair HC, Poliani PL, Marrella V, Ficara F, Cassani B, Facchetti F, Fontana E, Guerrini MM, Traggiai E, Schena F, Paulis M, Mantero S, Inforzato A, Valaperta S, Pangrazio A, Crisafulli L, Maina V, Kostenuik P, Vezzoni P, Villa A, Sobacchi C.

J Bone Miner Res. 2012 Dec;27(12):2501-10. doi: 10.1002/jbmr.1712.

50.

Anti-CD3ε mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications.

Marrella V, Poliani PL, Fontana E, Casati A, Maina V, Cassani B, Ficara F, Cominelli M, Schena F, Paulis M, Traggiai E, Vezzoni P, Grassi F, Villa A.

Blood. 2012 Aug 2;120(5):1005-14. doi: 10.1182/blood-2012-01-406827. Epub 2012 Jun 21.

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