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Items: 1 to 50 of 111

1.

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity.

Campesato LF, Silva APM, Cordeiro L, Correa BR, Navarro FCP, Zanin RF, Marçola M, Inoue LT, Duarte ML, Molgora M, Pasqualini F, Massara M, Galante P, Barroso-Sousa R, Polentarutti N, Riva F, Costa ET, Mantovani A, Garlanda C, Camargo AA.

Oncotarget. 2017 Jul 25;8(30):49470-49483. doi: 10.18632/oncotarget.17713.

2.

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A.

J Exp Med. 2017 May 1;214(5):1559. doi: 10.1084/jem.2015028204172017c. Epub 2017 Apr 18. No abstract available.

3.

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A.

J Exp Med. 2016 Sep 19;213(10):2167-85. doi: 10.1084/jem.20150282. Epub 2016 Sep 12. Erratum in: J Exp Med. 2017 May 1;214(5):1559.

4.

Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets.

Anselmo A, Riva F, Gentile S, Soldani C, Barbagallo M, Mazzon C, Feruglio F, Polentarutti N, Somma P, Carullo P, Angelini C, Bacci M, Mendolicchio GL, Voza A, Nebuloni M, Mantovani A, Garlanda C.

Cardiovasc Res. 2016 Sep;111(4):373-84. doi: 10.1093/cvr/cvw162. Epub 2016 Jun 13. Erratum in: Cardiovasc Res. 2017 Jan;113(1):112.

PMID:
27297888
5.

Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer.

Galdiero MR, Bianchi P, Grizzi F, Di Caro G, Basso G, Ponzetta A, Bonavita E, Barbagallo M, Tartari S, Polentarutti N, Malesci A, Marone G, Roncalli M, Laghi L, Garlanda C, Mantovani A, Jaillon S.

Int J Cancer. 2016 Jul 15;139(2):446-56. doi: 10.1002/ijc.30076. Epub 2016 Mar 24.

6.

Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.

Pentón-Rol G, Lagumersindez-Denis N, Muzio L, Bergami A, Furlan R, Fernández-Massó JR, Nazabal-Galvez M, Llópiz-Arzuaga A, Herrera-Rolo T, Veliz-Rodriguez T, Polentarutti N, Marín-Prida J, Raíces-Cruz I, Valenzuela-Silva C, Teixeira MM, Pentón-Arias E.

J Neuroimmune Pharmacol. 2016 Mar;11(1):153-67. doi: 10.1007/s11481-015-9642-9. Epub 2015 Nov 10.

PMID:
26556034
7.

Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.

Marín-Prida J, Pavón-Fuentes N, Llópiz-Arzuaga A, Fernández-Massó JR, Delgado-Roche L, Mendoza-Marí Y, Santana SP, Cruz-Ramírez A, Valenzuela-Silva C, Nazábal-Gálvez M, Cintado-Benítez A, Pardo-Andreu GL, Polentarutti N, Riva F, Pentón-Arias E, Pentón-Rol G.

Toxicol Appl Pharmacol. 2013 Oct 1;272(1):49-60. doi: 10.1016/j.taap.2013.05.021. Epub 2013 Jun 2.

PMID:
23732081
8.

Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.

Véliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C.

Infect Immun. 2012 Jan;80(1):100-9. doi: 10.1128/IAI.05695-11. Epub 2011 Oct 24.

9.

The therapeutic potential of the humoral pattern recognition molecule PTX3 in chronic lung infection caused by Pseudomonas aeruginosa.

Moalli F, Paroni M, Véliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C.

J Immunol. 2011 May 1;186(9):5425-34. doi: 10.4049/jimmunol.1002035. Epub 2011 Mar 25. Erratum in: J Immunol. 2011 Jun 15;186(12):7273.

10.

Experimental contamination assessment of a novel closed ultravitrification device.

Criado E, Moalli F, Polentarutti N, Albani E, Morreale G, Menduni F, Levi-Setti PE.

Fertil Steril. 2011 Apr;95(5):1777-9. doi: 10.1016/j.fertnstert.2010.12.044. Epub 2011 Jan 26.

PMID:
21269610
11.

The Toll-IL-1R member Tir8/SIGIRR negatively regulates adaptive immunity against kidney grafts.

Noris M, Cassis P, Azzollini N, Cavinato R, Cugini D, Casiraghi F, Aiello S, Solini S, Cassis L, Mister M, Todeschini M, Abbate M, Benigni A, Trionfini P, Tomasoni S, Mele C, Garlanda C, Polentarutti N, Mantovani A, Remuzzi G.

J Immunol. 2009 Oct 1;183(7):4249-60. doi: 10.4049/jimmunol.0803549. Epub 2009 Sep 4.

12.

The expression pattern of TIR8 is conserved among vertebrates.

Riva F, Polentarutti N, Tribbioli G, Mantovani A, Garlanda C, Turin L.

Vet Immunol Immunopathol. 2009 Sep 15;131(1-2):44-9. doi: 10.1016/j.vetimm.2009.03.009. Epub 2009 Mar 24.

PMID:
19386369
13.

Evaluation of proopiomelanocortin mRNA in the peripheral blood from patients with Cushing's syndrome of different origin.

Bondioni S, Mantovani G, Polentarutti N, Ambrosi B, Loli P, Peverelli E, Lania AG, Beck-Peccoz P, Spada A.

J Endocrinol Invest. 2007 Nov;30(10):828-32.

PMID:
18075284
14.

High expression of PKA regulatory subunit 1A protein is related to proliferation of human melanoma cells.

Mantovani G, Bondioni S, Lania AG, Rodolfo M, Peverelli E, Polentarutti N, Veliz Rodriguez T, Ferrero S, Bosari S, Beck-Peccoz P, Spada A.

Oncogene. 2008 Mar 20;27(13):1834-43. Epub 2007 Oct 1.

PMID:
17906691
15.

Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family.

Garlanda C, Riva F, Veliz T, Polentarutti N, Pasqualini F, Radaelli E, Sironi M, Nebuloni M, Zorini EO, Scanziani E, Mantovani A.

Cancer Res. 2007 Jul 1;67(13):6017-21.

16.

Regulation of the microsomal prostaglandin E synthase-1 in polarized mononuclear phagocytes and its constitutive expression in neutrophils.

Mosca M, Polentarutti N, Mangano G, Apicella C, Doni A, Mancini F, De Bortoli M, Coletta I, Polenzani L, Santoni G, Sironi M, Vecchi A, Mantovani A.

J Leukoc Biol. 2007 Aug;82(2):320-6. Epub 2007 May 15.

PMID:
17505022
17.

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

Sironi M, Martinez FO, D'Ambrosio D, Gattorno M, Polentarutti N, Locati M, Gregorio A, Iellem A, Cassatella MA, Van Damme J, Sozzani S, Martini A, Sinigaglia F, Vecchi A, Mantovani A.

J Leukoc Biol. 2006 Aug;80(2):342-9. Epub 2006 May 30.

PMID:
16735693
18.

Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL-10 and inhibition by IFN-gamma.

Doni A, Michela M, Bottazzi B, Peri G, Valentino S, Polentarutti N, Garlanda C, Mantovani A.

J Leukoc Biol. 2006 Apr;79(4):797-802. Epub 2006 Feb 3.

PMID:
16461742
19.

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family.

Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, De Bortoli M, Muzio M, Bergottini R, Scanziani E, Vecchi A, Hirsch E, Mantovani A.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3522-6. Epub 2004 Mar 1.

20.

Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

Polentarutti N, Rol GP, Muzio M, Bosisio D, Camnasio M, Riva F, Zoja C, Benigni A, Tomasoni S, Vecchi A, Garlanda C, Mantovani A.

Eur Cytokine Netw. 2003 Oct-Dec;14(4):211-8.

21.

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.

Mantovani A, Locati M, Polentarutti N, Vecchi A, Garlanda C.

J Leukoc Biol. 2004 May;75(5):738-42. Epub 2003 Dec 12. Review.

PMID:
14673019
22.

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells.

Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A.

Blood. 2003 Aug 1;102(3):956-63. Epub 2003 Apr 10.

23.

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide.

Bosisio D, Polentarutti N, Sironi M, Bernasconi S, Miyake K, Webb GR, Martin MU, Mantovani A, Muzio M.

Blood. 2002 May 1;99(9):3427-31.

24.

Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells.

Faure E, Equils O, Sieling PA, Thomas L, Zhang FX, Kirschning CJ, Polentarutti N, Muzio M, Arditi M.

J Biol Chem. 2000 Apr 14;275(15):11058-63.

25.

Toll-like receptor family and signalling pathway.

Muzio M, Polentarutti N, Bosisio D, Manoj Kumar PP, Mantovani A.

Biochem Soc Trans. 2000 Oct;28(5):563-6. Review. Erratum in: Biochem Soc Trans 2001 Nov;29(Pt 6):869.

PMID:
11044375
26.

Increased peripheral benzodiazepine binding sites and pentraxin 3 expression in the spinal cord during EAE: relation to inflammatory cytokines and modulation by dexamethasone and rolipram.

Agnello D, Carvelli L, Muzio V, Villa P, Bottazzi B, Polentarutti N, Mennini T, Mantovani A, Ghezzi P.

J Neuroimmunol. 2000 Sep 22;109(2):105-11.

PMID:
10996212
27.

Inhibition of monocyte chemotactic protein-1 synthesis by statins.

Romano M, Diomede L, Sironi M, Massimiliano L, Sottocorno M, Polentarutti N, Guglielmotti A, Albani D, Bruno A, Fruscella P, Salmona M, Vecchi A, Pinza M, Mantovani A.

Lab Invest. 2000 Jul;80(7):1095-100.

PMID:
10908155
28.

Selectivity release of the type II decoy IL-1 receptor.

Orlando S, Polentarutti N, Mantovani A.

Cytokine. 2000 Jul;12(7):1001-6.

PMID:
10880245
29.

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells.

Muzio M, Bosisio D, Polentarutti N, D'amico G, Stoppacciaro A, Mancinelli R, van't Veer C, Penton-Rol G, Ruco LP, Allavena P, Mantovani A.

J Immunol. 2000 Jun 1;164(11):5998-6004.

30.

Inducible expression of the long pentraxin PTX3 in the central nervous system.

Polentarutti N, Bottazzi B, Di Santo E, Blasi E, Agnello D, Ghezzi P, Introna M, Bartfai T, Richards G, Mantovani A.

J Neuroimmunol. 2000 Jul 1;106(1-2):87-94.

PMID:
10814786
31.

Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes.

Muzio M, Polentarutti N, Bosisio D, Prahladan MK, Mantovani A.

J Leukoc Biol. 2000 Apr;67(4):450-6.

PMID:
10770275
32.

Selective induction of MCP-1 in human mesangial cells by the IL-6/sIL-6R complex.

Coletta I, Soldo L, Polentarutti N, Mancini F, Guglielmotti A, Pinza M, Mantovani A, Milanese C.

Exp Nephrol. 2000 Jan-Feb;8(1):37-43.

PMID:
10644881
33.

Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages.

Sica A, Saccani A, Bottazzi B, Polentarutti N, Vecchi A, van Damme J, Mantovani A.

J Immunol. 2000 Jan 15;164(2):762-7.

34.

Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones.

Penton-Rol G, Cota M, Polentarutti N, Luini W, Bernasconi S, Borsatti A, Sica A, LaRosa GJ, Sozzani S, Poli G, Mantovani A.

J Immunol. 1999 Sep 15;163(6):3524-9.

35.

A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1.

Sironi M, Guglielmotti A, Polentarutti N, Fioretti F, Milanese C, Romano M, Vigini C, Coletta I, Sozzani S, Bernasconi S, Vecchi A, Pinza M, Mantovani A.

Eur Cytokine Netw. 1999 Sep;10(3):437-42.

36.

Characterization of type II intracellular IL-1 receptor antagonist (IL-1ra3): a depot IL-1ra.

Muzio M, Polentarutti N, Facchetti F, Peri G, Doni A, Sironi M, Transidico P, Salmona M, Introna M, Mantovani A.

Eur J Immunol. 1999 Mar;29(3):781-8.

38.

Up-regulation of CCR1 and CCR3 and induction of chemotaxis to CC chemokines by IFN-gamma in human neutrophils.

Bonecchi R, Polentarutti N, Luini W, Borsatti A, Bernasconi S, Locati M, Power C, Proudfoot A, Wells TN, Mackay C, Mantovani A, Sozzani S.

J Immunol. 1999 Jan 1;162(1):474-9.

39.

Divergent effects of LPS on expression of IL-1 receptor family members in mononuclear phagocytes in vitro and in vivo.

Saccani S, Polentarutti N, Penton-Rol G, Sims JE, Mantovani A.

Cytokine. 1998 Oct;10(10):773-80.

PMID:
9811530
40.

Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma.

Penton-Rol G, Polentarutti N, Luini W, Borsatti A, Mancinelli R, Sica A, Sozzani S, Mantovani A.

J Immunol. 1998 Apr 15;160(8):3869-73.

41.

Interferon-gamma inhibits expression of the long pentraxin PTX3 in human monocytes.

Polentarutti N, Picardi G, Basile A, Cenzuales S, Rivolta A, Matteucci C, Peri G, Mantovani A, Introna M.

Eur J Immunol. 1998 Feb;28(2):496-501.

42.

Interleukin 10 increases CCR5 expression and HIV infection in human monocytes.

Sozzani S, Ghezzi S, Iannolo G, Luini W, Borsatti A, Polentarutti N, Sica A, Locati M, Mackay C, Wells TN, Biswas P, Vicenzi E, Poli G, Mantovani A.

J Exp Med. 1998 Feb 2;187(3):439-44.

43.

Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line.

Biswas P, Delfanti F, Bernasconi S, Mengozzi M, Cota M, Polentarutti N, Mantovani A, Lazzarin A, Sozzani S, Poli G.

Blood. 1998 Jan 1;91(1):258-65.

44.

Expression of monocyte chemotactic protein-3 in human monocytes and endothelial cells.

Polentarutti N, Introna M, Sozzani S, Mancinelli R, Mantovani G, Mantovani A.

Eur Cytokine Netw. 1997 Sep;8(3):271-4.

45.

Gene transfer-mediated expression of physiological numbers of the type II decoy receptor in a myelomonocytic cellular context dampens the response to interleukin-1.

Penton Rol G, Polentarutti N, Sironi M, Saccani S, Introna M, Mantovani A.

Eur Cytokine Netw. 1997 Sep;8(3):265-9.

46.

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.

Sozzani S, Luini W, Borsatti A, Polentarutti N, Zhou D, Piemonti L, D'Amico G, Power CA, Wells TN, Gobbi M, Allavena P, Mantovani A.

J Immunol. 1997 Aug 15;159(4):1993-2000.

PMID:
9257866
47.

MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression.

Sozzani S, Introna M, Bernasconi S, Polentarutti N, Cinque P, Poli G, Sica A, Mantovani A.

J Leukoc Biol. 1997 Jul;62(1):30-3. Review.

PMID:
9225989
48.

IL-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: characterization of a predominant 3.4-kilobase transcript containing CCR2B and CCR2A sequences.

Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M.

J Immunol. 1997 Mar 15;158(6):2689-94.

PMID:
9058802
49.

Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes.

Sica A, Saccani A, Borsatti A, Power CA, Wells TN, Luini W, Polentarutti N, Sozzani S, Mantovani A.

J Exp Med. 1997 Mar 3;185(5):969-74.

50.

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

Romano M, Sironi M, Toniatti C, Polentarutti N, Fruscella P, Ghezzi P, Faggioni R, Luini W, van Hinsbergh V, Sozzani S, Bussolino F, Poli V, Ciliberto G, Mantovani A.

Immunity. 1997 Mar;6(3):315-25.

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