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Items: 18

1.

Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells.

Truong KL, Schlickeiser S, Vogt K, Boës D, Stanko K, Appelt C, Streitz M, Grütz G, Stobutzki N, Meisel C, Iwert C, Tomiuk S, Polansky JK, Pascher A, Babel N, Stervbo U, Sauer I, Gerlach U, Sawitzki B.

Nat Commun. 2019 May 22;10(1):2263. doi: 10.1038/s41467-019-10018-1.

2.

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains.

Salhab A, Nordström K, Gasparoni G, Kattler K, Ebert P, Ramirez F, Arrigoni L, Müller F, Polansky JK, Cadenas C, G Hengstler J, Lengauer T, Manke T; DEEP Consortium, Walter J.

Genome Biol. 2018 Sep 28;19(1):150. doi: 10.1186/s13059-018-1510-5.

3.

CD137+CD154- Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures.

Nowak A, Lock D, Bacher P, Hohnstein T, Vogt K, Gottfreund J, Giehr P, Polansky JK, Sawitzki B, Kaiser A, Walter J, Scheffold A.

Front Immunol. 2018 Feb 7;9:199. doi: 10.3389/fimmu.2018.00199. eCollection 2018.

4.

Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4+ memory T cells.

Szilagyi BA, Triebus J, Kressler C, de Almeida M, Tierling S, Durek P, Mardahl M, Szilagyi A, Floess S, Huehn J, Syrbe U, Walter J, Polansky JK, Hamann A.

Mucosal Immunol. 2017 Nov;10(6):1443-1454. doi: 10.1038/mi.2017.7. Epub 2017 Feb 15.

PMID:
28198363
5.

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.

Schmidt F, Gasparoni N, Gasparoni G, Gianmoena K, Cadenas C, Polansky JK, Ebert P, Nordström K, Barann M, Sinha A, Fröhler S, Xiong J, Dehghani Amirabad A, Behjati Ardakani F, Hutter B, Zipprich G, Felder B, Eils J, Brors B, Chen W, Hengstler JG, Hamann A, Lengauer T, Rosenstiel P, Walter J, Schulz MH.

Nucleic Acids Res. 2017 Jan 9;45(1):54-66. doi: 10.1093/nar/gkw1061. Epub 2016 Nov 29.

6.

Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.

Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L; DEEP Consortium, Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK.

Immunity. 2016 Nov 15;45(5):1148-1161. doi: 10.1016/j.immuni.2016.10.022.

7.

Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.

Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U.

J Immunol. 2016 Oct 15;197(8):3406-3414. Epub 2016 Sep 2.

8.

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4(+) memory T cells.

Kinkley S, Helmuth J, Polansky JK, Dunkel I, Gasparoni G, Fröhler S, Chen W, Walter J, Hamann A, Chung HR.

Nat Commun. 2016 Aug 17;7:12514. doi: 10.1038/ncomms12514.

9.

Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.

Goldstein JD, Burlion A, Zaragoza B, Sendeyo K, Polansky JK, Huehn J, Piaggio E, Salomon BL, Marodon G.

PLoS One. 2016 Apr 14;11(4):e0153682. doi: 10.1371/journal.pone.0153682. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0157629.

10.

High dose CD11c-driven IL15 is sufficient to drive NK cell maturation and anti-tumor activity in a trans-presentation independent manner.

Polansky JK, Bahri R, Divivier M, Duitman EH, Vock C, Goyeneche-Patino DA, Orinska Z, Bulfone-Paus S.

Sci Rep. 2016 Jan 29;6:19699. doi: 10.1038/srep19699.

11.

IL-15 suppresses colitis-associated colon carcinogenesis by inducing antitumor immunity.

Bahri R, Pateras IS, D'Orlando O, Goyeneche-Patino DA, Campbell M, Polansky JK, Sandig H, Papaioannou M, Evangelou K, Foukas PG, Gorgoulis VG, Bulfone-Paus S.

Oncoimmunology. 2015 Jan 22;4(9):e1002721. eCollection 2015 Sep.

12.

[Epigenetic analyses - new therapeutic approaches for rheumatic diseases?].

Polansky JK, Syrbe U, Hamann A.

Z Rheumatol. 2013 Oct;72(8):804-8. doi: 10.1007/s00393-012-1121-6. German. No abstract available.

PMID:
24122220
13.

Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.

Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J.

J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18.

14.

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells.

Polansky JK, Schreiber L, Thelemann C, Ludwig L, Krüger M, Baumgrass R, Cording S, Floess S, Hamann A, Huehn J.

J Mol Med (Berl). 2010 Oct;88(10):1029-40. doi: 10.1007/s00109-010-0642-1. Epub 2010 Jun 24.

15.

Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?

Huehn J, Polansky JK, Hamann A.

Nat Rev Immunol. 2009 Feb;9(2):83-9. doi: 10.1038/nri2474. Review.

PMID:
19114986
16.

DNA methylation controls Foxp3 gene expression.

Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J.

Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105.

17.

[To be or not to be a Treg: epigenetic regulation of Foxp3 expression in regulatory T cells].

Polansky JK, Huehn J.

Z Rheumatol. 2007 Sep;66(5):417-20. German.

PMID:
17717678
18.

Foxp3 occupancy and regulation of key target genes during T-cell stimulation.

Marson A, Kretschmer K, Frampton GM, Jacobsen ES, Polansky JK, MacIsaac KD, Levine SS, Fraenkel E, von Boehmer H, Young RA.

Nature. 2007 Feb 22;445(7130):931-5. Epub 2007 Jan 21.

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