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Items: 1 to 50 of 209

1.

RAbHIT: R Antibody Haplotype Inference Tool.

Peres A, Gidoni M, Polak P, Yaari G.

Bioinformatics. 2019 Jun 7. pii: btz481. doi: 10.1093/bioinformatics/btz481. [Epub ahead of print]

PMID:
31173062
2.

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues.

Yizhak K, Aguet F, Kim J, Hess JM, Kübler K, Grimsby J, Frazer R, Zhang H, Haradhvala NJ, Rosebrock D, Livitz D, Li X, Arich-Landkof E, Shoresh N, Stewart C, Segrè AV, Branton PA, Polak P, Ardlie KG, Getz G.

Science. 2019 Jun 7;364(6444). pii: eaaw0726. doi: 10.1126/science.aaw0726.

PMID:
31171663
3.

Journey's End: the quest for BRCA-like hereditary breast cancer genes is nearly over.

Foulkes WD, Polak P.

Ann Oncol. 2019 May 15. pii: mdz152. doi: 10.1093/annonc/mdz152. [Epub ahead of print] No abstract available.

PMID:
31090898
4.

Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping.

Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, Sarna VK, Lundin KEA, Clouser C, Vigneault F, Collins AM, Sollid LM, Yaari G.

Nat Commun. 2019 Feb 7;10(1):628. doi: 10.1038/s41467-019-08489-3.

5.

Antibody Repertoire Analysis of Hepatitis C Virus Infections Identifies Immune Signatures Associated With Spontaneous Clearance.

Eliyahu S, Sharabi O, Elmedvi S, Timor R, Davidovich A, Vigneault F, Clouser C, Hope R, Nimer A, Braun M, Weiss YY, Polak P, Yaari G, Gal-Tanamy M.

Front Immunol. 2018 Dec 21;9:3004. doi: 10.3389/fimmu.2018.03004. eCollection 2018.

6.

A single-arm, open-label study to assess the immunogenicity, safety, and efficacy of etanercept manufactured using the serum-free, high-capacity manufacturing process administered to patients with rheumatoid arthritis.

Polák P, Peric P, Louw I, Gaylord SM, Williams T, Becker JC, Pedersen R, Korth-Bradley J, Vlahos B.

Eur J Rheumatol. 2019 Jan;6(1):23-28. doi: 10.5152/eurjrheum.2018.18078.

7.

Novel POLE pathogenic germline variant in a family with multiple primary tumors results in distinct mutational signatures.

Castellsagué E, Li R, Aligue R, González S, Sanz J, Martin E, Velasco À, Capellá G, Stewart CJR, Vidal A, Majewski J, Rivera B, Polak P, Matias-Guiu X, Brunet J, Foulkes WD.

Hum Mutat. 2019 Jan;40(1):36-41. doi: 10.1002/humu.23676. Epub 2018 Nov 20.

PMID:
30362666
8.

Methodology to estimate the break force of pharmaceutical tablets with curved faces under diametrical compression.

Al-Sabbagh M, Polak P, Roberts RJ, Reynolds GK, Sinka IC.

Int J Pharm. 2019 Jan 10;554:399-419. doi: 10.1016/j.ijpharm.2018.10.014. Epub 2018 Oct 8.

PMID:
30308275
9.

Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors.

Miao D, Margolis CA, Vokes NI, Liu D, Taylor-Weiner A, Wankowicz SM, Adeegbe D, Keliher D, Schilling B, Tracy A, Manos M, Chau NG, Hanna GJ, Polak P, Rodig SJ, Signoretti S, Sholl LM, Engelman JA, Getz G, Jänne PA, Haddad RI, Choueiri TK, Barbie DA, Haq R, Awad MM, Schadendorf D, Hodi FS, Bellmunt J, Wong KK, Hammerman P, Van Allen EM.

Nat Genet. 2018 Sep;50(9):1271-1281. doi: 10.1038/s41588-018-0200-2. Epub 2018 Aug 27.

10.

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.

Gopal RK, Kübler K, Calvo SE, Polak P, Livitz D, Rosebrock D, Sadow PM, Campbell B, Donovan SE, Amin S, Gigliotti BJ, Grabarek Z, Hess JM, Stewart C, Braunstein LZ, Arndt PF, Mordecai S, Shih AR, Chaves F, Zhan T, Lubitz CC, Kim J, Iafrate AJ, Wirth L, Parangi S, Leshchiner I, Daniels GH, Mootha VK, Dias-Santagata D, Getz G, McFadden DG.

Cancer Cell. 2018 Aug 13;34(2):242-255.e5. doi: 10.1016/j.ccell.2018.06.013.

PMID:
30107175
11.

Multimodal Imaging of Retired Professional Contact Sport Athletes Does Not Provide Evidence of Structural and Functional Brain Damage.

Zivadinov R, Polak P, Schweser F, Bergsland N, Hagemeier J, Dwyer MG, Ramasamy DP, Baker JG, Leddy JJ, Willer BS.

J Head Trauma Rehabil. 2018 Sep/Oct;33(5):E24-E32. doi: 10.1097/HTR.0000000000000422.

PMID:
30080799
12.

Spatiotemporal epidemiology of rabies at an interface between domestic dogs and wildlife in South Africa.

Grover M, Bessell PR, Conan A, Polak P, Sabeta CT, Reininghaus B, Knobel DL.

Sci Rep. 2018 Jul 18;8(1):10864. doi: 10.1038/s41598-018-29045-x.

13.

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M.

Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18.

PMID:
29909985
14.

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair.

Haradhvala NJ, Kim J, Maruvka YE, Polak P, Rosebrock D, Livitz D, Hess JM, Leshchiner I, Kamburov A, Mouw KW, Lawrence MS, Getz G.

Nat Commun. 2018 May 1;9(1):1746. doi: 10.1038/s41467-018-04002-4.

15.

Monogenic Diseases of DNA Repair.

Rivera B, Polak P, Foulkes WD.

N Engl J Med. 2018 Feb 1;378(5):491. doi: 10.1056/NEJMc1716072. No abstract available.

PMID:
29394477
16.

Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.

Wardell CP, Fujita M, Yamada T, Simbolo M, Fassan M, Karlic R, Polak P, Kim J, Hatanaka Y, Maejima K, Lawlor RT, Nakanishi Y, Mitsuhashi T, Fujimoto A, Furuta M, Ruzzenente A, Conci S, Oosawa A, Sasaki-Oku A, Nakano K, Tanaka H, Yamamoto Y, Michiaki K, Kawakami Y, Aikata H, Ueno M, Hayami S, Gotoh K, Ariizumi SI, Yamamoto M, Yamaue H, Chayama K, Miyano S, Getz G, Scarpa A, Hirano S, Nakamura T, Nakagawa H.

J Hepatol. 2018 May;68(5):959-969. doi: 10.1016/j.jhep.2018.01.009. Epub 2018 Jan 31.

17.

Is the consumption of snail meat actually healthy? An analysis of the osteotropic influence of snail meat as a sole source of protein in growing rats.

Radzki RP, Bieńko M, Polak P, Szkucik K, Ziomek M, Ostapiuk M, Bieniaś J.

J Anim Physiol Anim Nutr (Berl). 2018 Apr;102(2):e885-e891. doi: 10.1111/jpn.12851. Epub 2017 Dec 7.

PMID:
29218776
18.

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M.

Nat Commun. 2017 Nov 6;8(1):1324. doi: 10.1038/s41467-017-00965-y.

19.

Analysis of somatic microsatellite indels identifies driver events in human tumors.

Maruvka YE, Mouw KW, Karlic R, Parasuraman P, Kamburov A, Polak P, Haradhvala NJ, Hess JM, Rheinbay E, Brody Y, Koren A, Braunstein LZ, D'Andrea A, Lawrence MS, Bass A, Bernards A, Michor F, Getz G.

Nat Biotechnol. 2017 Oct;35(10):951-959. doi: 10.1038/nbt.3966. Epub 2017 Sep 11.

PMID:
28892075
20.

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.

Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G.

Nat Genet. 2017 Oct;49(10):1476-1486. doi: 10.1038/ng.3934. Epub 2017 Aug 21.

PMID:
28825726
21.

Social inhibition and emotional distress in patients with coronary artery disease: The Type D personality construct.

Timmermans I, Versteeg H, Duijndam S, Graafmans C, Polak P, Denollet J.

J Health Psychol. 2017 May 1:1359105317709513. doi: 10.1177/1359105317709513. [Epub ahead of print]

PMID:
28810489
22.

Dearomatization Strategy for the Synthesis of Arylated 2H-Pyrroles and 2,3,5-Trisubstituted 1H-Pyrroles.

Polák P, Tobrman T.

Org Lett. 2017 Sep 1;19(17):4608-4611. doi: 10.1021/acs.orglett.7b02219. Epub 2017 Aug 14.

PMID:
28805398
23.

Effect of teriflunomide on cortex-basal ganglia-thalamus (CxBGTh) circuit glutamatergic dysregulation in the Theiler's Murine Encephalomyelitis Virus mouse model of multiple sclerosis.

Modica CM, Schweser F, Sudyn ML, Bertolino N, Preda M, Polak P, Siebert DM, Krawiecki JC, Sveinsson M, Hagemeier J, Dwyer MG, Pol S, Zivadinov R.

PLoS One. 2017 Aug 10;12(8):e0182729. doi: 10.1371/journal.pone.0182729. eCollection 2017.

24.

The synthesis of polysubstituted indoles from 3-bromo-2-indolyl phosphates.

Polák P, Tobrman T.

Org Biomol Chem. 2017 Jul 26;15(29):6233-6241. doi: 10.1039/c7ob01127j.

PMID:
28702629
25.

Changes of deep gray matter magnetic susceptibility over 2 years in multiple sclerosis and healthy control brain.

Hagemeier J, Zivadinov R, Dwyer MG, Polak P, Bergsland N, Weinstock-Guttman B, Zalis J, Deistung A, Reichenbach JR, Schweser F.

Neuroimage Clin. 2017 Apr 13;18:1007-1016. doi: 10.1016/j.nicl.2017.04.008. eCollection 2018.

26.

Methods for the computation of templates from quantitative magnetic susceptibility maps (QSM): Toward improved atlas- and voxel-based analyses (VBA).

Hanspach J, Dwyer MG, Bergsland NP, Feng X, Hagemeier J, Bertolino N, Polak P, Reichenbach JR, Zivadinov R, Schweser F.

J Magn Reson Imaging. 2017 Nov;46(5):1474-1484. doi: 10.1002/jmri.25671. Epub 2017 Mar 6.

27.

Does the Use of a Decision Aid Improve Decision Making in Prosthetic Heart Valve Selection? A Multicenter Randomized Trial.

Korteland NM, Ahmed Y, Koolbergen DR, Brouwer M, de Heer F, Kluin J, Bruggemans EF, Klautz RJ, Stiggelbout AM, Bucx JJ, Roos-Hesselink JW, Polak P, Markou T, van den Broek I, Ligthart R, Bogers AJ, Takkenberg JJ.

Circ Cardiovasc Qual Outcomes. 2017 Feb;10(2). pii: e003178. doi: 10.1161/CIRCOUTCOMES.116.003178. Epub 2017 Feb 22.

PMID:
28228452
28.

An improved FSL-FIRST pipeline for subcortical gray matter segmentation to study abnormal brain anatomy using quantitative susceptibility mapping (QSM).

Feng X, Deistung A, Dwyer MG, Hagemeier J, Polak P, Lebenberg J, Frouin F, Zivadinov R, Reichenbach JR, Schweser F.

Magn Reson Imaging. 2017 Jun;39:110-122. doi: 10.1016/j.mri.2017.02.002. Epub 2017 Feb 7.

29.

Possibility of Coagulation System Activation Determination with Tissue Factor in Pregnancy Complications.

Slavik L, Novak M, Ulehlova J, Prochazka M, Prochazkova J, Lattova V, Polak P, Pilka R.

Clin Lab. 2016 Oct 1;62(10):1851-1856. doi: 10.7754/Clin.Lab.2016.151234.

PMID:
28164533
30.

In Vitro Antiproliferative and Antioxidant Effects of Extracts from Rubus caesius Leaves and Their Quality Evaluation.

Grochowski DM, Paduch R, Wiater A, Dudek A, Pleszczyńska M, Tomczykowa M, Granica S, Polak P, Tomczyk M.

Evid Based Complement Alternat Med. 2016;2016:5698685. doi: 10.1155/2016/5698685. Epub 2016 Dec 22.

31.

Selective inactivation of enzymes conjugated to nanoparticles using tuned laser illumination.

Ilovitsh A, Polak P, Zalevsky Z, Shefi O.

Cytometry A. 2017 Aug;91(8):767-774. doi: 10.1002/cyto.a.23005. Epub 2016 Dec 2.

32.

[Is it necessary to revaccinate against hepatitis B virus when the titer of anti-HBs drops below 10 IU/L?]

Polák P, Husa P, Smejkal P, Kamelander J, Chlupová G, Penka M.

Klin Mikrobiol Infekc Lek. 2016 Sep;22(3):125-130. Czech.

PMID:
27907975
33.

Leptomeningeal contrast enhancement is associated with progression of cortical atrophy in MS: A retrospective, pilot, observational longitudinal study.

Zivadinov R, Ramasamy DP, Vaneckova M, Gandhi S, Chandra A, Hagemeier J, Bergsland N, Polak P, Benedict RH, Hojnacki D, Weinstock-Guttman B.

Mult Scler. 2017 Sep;23(10):1336-1345. doi: 10.1177/1352458516678083. Epub 2016 Nov 4.

PMID:
27811339
34.

THE EFFECT OF METHANOL USED AS VEHICULUM ON SERUM PHENACETIN CONCENTRATION IN THE RAT.

Lukasik M, Malkowska A, Bamburowicz-Klimkowska M, Polak P, Szutowski MM.

Acta Pol Pharm. 2016 Sep;73(5):1129-1137.

PMID:
29638053
35.

Differential effects on glial activation by a direct versus an indirect thrombin inhibitor.

Marangoni MN, Braun D, Situ A, Moyano AL, Kalinin S, Polak P, Givogri MI, Feinstein DL.

J Neuroimmunol. 2016 Aug 15;297:159-68. doi: 10.1016/j.jneuroim.2016.05.018. Epub 2016 May 24.

PMID:
27397090
36.

[Fecal microbiota transplantation].

Polák P.

Vnitr Lek. 2016 Feb;62(2):92-4. Czech. No abstract available.

PMID:
27358976
37.

[Treatment with rituximab as an opportunity for the prevention of infectious complications].

Polák P, Penka M, Smejkal P, Chlupová G.

Vnitr Lek. Spring 2016;62(5):398-405. Czech.

PMID:
27319233
38.

Cerebral Microbleeds in Multiple Sclerosis Evaluated on Susceptibility-weighted Images and Quantitative Susceptibility Maps: A Case-Control Study.

Zivadinov R, Ramasamy DP, Benedict RR, Polak P, Hagemeier J, Magnano C, Dwyer MG, Bergsland N, Bertolino N, Weinstock-Guttman B, Kolb C, Hojnacki D, Utriainen D, Haacke EM, Schweser F.

Radiology. 2016 Dec;281(3):884-895. Epub 2016 Jun 16.

PMID:
27308776
39.

[Severe osteoporosis - the story of chronic medication-related hyponatremia].

Polák P, Husa P, Kubešová HM.

Vnitr Lek. 2016 Feb;62(2):152-6. Czech.

PMID:
27172443
40.

Membrane Cholesterol Modulates Superwarfarin Toxicity.

Marangoni MN, Martynowycz MW, Kuzmenko I, Braun D, Polak PE, Weinberg G, Rubinstein I, Gidalevitz D, Feinstein DL.

Biophys J. 2016 Apr 26;110(8):1777-1788. doi: 10.1016/j.bpj.2016.03.004.

41.

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors.

Kim J, Mouw KW, Polak P, Braunstein LZ, Kamburov A, Kwiatkowski DJ, Rosenberg JE, Van Allen EM, D'Andrea A, Getz G.

Nat Genet. 2016 Jun;48(6):600-606. doi: 10.1038/ng.3557. Epub 2016 Apr 25.

42.

Ethanol-induced conditioned taste aversion in Warsaw Alcohol High-Preferring (WHP) and Warsaw Alcohol Low-Preferring (WLP) rats.

Dyr W, Wyszogrodzka E, Paterak J, Siwińska-Ziółkowska A, Małkowska A, Polak P.

Alcohol. 2016 Mar;51:63-9. doi: 10.1016/j.alcohol.2015.11.011. Epub 2016 Jan 30.

PMID:
26992702
43.

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.

Haradhvala NJ, Polak P, Stojanov P, Covington KR, Shinbrot E, Hess JM, Rheinbay E, Kim J, Maruvka YE, Braunstein LZ, Kamburov A, Hanawalt PC, Wheeler DA, Koren A, Lawrence MS, Getz G.

Cell. 2016 Jan 28;164(3):538-49. doi: 10.1016/j.cell.2015.12.050. Epub 2016 Jan 21.

44.

[Fecal bacteriotherapy for the treatment of recurrent Clostridium difficile colitis used in the Clinic of Infectious Diseases of the University Hospital Brno in 2010-2014 - a prospective study].

Polák P, Freibergerová M, Husa P, Juránková J, Svačinka R, Mikešová L, Kocourková H, Mihalčin M, Skalická R, Stebel R, Porubčanová M.

Epidemiol Mikrobiol Imunol. 2015 Oct;64(4):232-5. Czech.

PMID:
26795227
45.

Imaging Chronic Traumatic Encephalopathy: A Biomedical Engineering Perspective.

Polak P, Tuyl JV, Engel R.

Crit Rev Biomed Eng. 2016;44(6):473-492. doi: 10.1615/CritRevBiomedEng.2017021970.

PMID:
29431093
46.

Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution.

Kasar S, Kim J, Improgo R, Tiao G, Polak P, Haradhvala N, Lawrence MS, Kiezun A, Fernandes SM, Bahl S, Sougnez C, Gabriel S, Lander ES, Kim HT, Getz G, Brown JR.

Nat Commun. 2015 Dec 7;6:8866. doi: 10.1038/ncomms9866.

47.

[40-year old patient with strongly distended abdomen and diarrhea].

Polák P, Husa P, Nebeský T.

Dtsch Med Wochenschr. 2015 Nov;140(23):1731. doi: 10.1055/s-0041-103548. Epub 2015 Nov 19. German. No abstract available.

PMID:
26583815
48.

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions.

Kazanov MD, Roberts SA, Polak P, Stamatoyannopoulos J, Klimczak LJ, Gordenin DA, Sunyaev SR.

Cell Rep. 2015 Nov 10;13(6):1103-1109. doi: 10.1016/j.celrep.2015.09.077. Epub 2015 Oct 29.

49.

[Campylobacteriosis at the Department of Infectious Diseases of the University Hospital Brno in 2011-2013: a retrospective study].

Polák P, Vrba M, Bortlíček Z, Juránková J, Freibergerová M, Husa P, Kamelander J, Dastych M.

Epidemiol Mikrobiol Imunol. 2015 Sep;64(3):153-9. Czech.

PMID:
26448303
50.

Comprehensive assessment of cancer missense mutation clustering in protein structures.

Kamburov A, Lawrence MS, Polak P, Leshchiner I, Lage K, Golub TR, Lander ES, Getz G.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5486-95. doi: 10.1073/pnas.1516373112. Epub 2015 Sep 21.

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