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Items: 1 to 50 of 51

1.

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.

Pardi N, LaBranche CC, Ferrari G, Cain DW, Tombácz I, Parks RJ, Muramatsu H, Mui BL, Tam YK, Karikó K, Polacino P, Barbosa CJ, Madden TD, Hope MJ, Haynes BF, Montefiori DC, Hu SL, Weissman D.

Mol Ther Nucleic Acids. 2019 Apr 15;15:36-47. doi: 10.1016/j.omtn.2019.03.003. Epub 2019 Mar 21.

2.

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation.

Colonna L, Peterson CW, Schell JB, Carlson JM, Tkachev V, Brown M, Yu A, Reddy S, Obenza WM, Nelson V, Polacino PS, Mack H, Hu SL, Zeleski K, Hoffman M, Olvera J, Furlan SN, Zheng H, Taraseviciute A, Hunt DJ, Betz K, Lane JF, Vogel K, Hotchkiss CE, Moats C, Baldessari A, Murnane RD, English C, Astley CA, Wangari S, Agricola B, Ahrens J, Iwayama N, May A, Stensland L, Huang MW, Jerome KR, Kiem HP, Kean LS.

Nat Commun. 2018 Oct 25;9(1):4438. doi: 10.1038/s41467-018-06736-7.

3.

Intestinal damage precedes mucosal immune dysfunction in SIV infection.

Hensley-McBain T, Berard AR, Manuzak JA, Miller CJ, Zevin AS, Polacino P, Gile J, Agricola B, Cameron M, Hu SL, Estes JD, Reeves RK, Smedley J, Keele BF, Burgener AD, Klatt NR.

Mucosal Immunol. 2018 Sep;11(5):1429-1440. doi: 10.1038/s41385-018-0032-5. Epub 2018 Jun 15.

4.

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

Pardi N, Hogan MJ, Naradikian MS, Parkhouse K, Cain DW, Jones L, Moody MA, Verkerke HP, Myles A, Willis E, LaBranche CC, Montefiori DC, Lobby JL, Saunders KO, Liao HX, Korber BT, Sutherland LL, Scearce RM, Hraber PT, Tombácz I, Muramatsu H, Ni H, Balikov DA, Li C, Mui BL, Tam YK, Krammer F, Karikó K, Polacino P, Eisenlohr LC, Madden TD, Hope MJ, Lewis MG, Lee KK, Hu SL, Hensley SE, Cancro MP, Haynes BF, Weissman D.

J Exp Med. 2018 Jun 4;215(6):1571-1588. doi: 10.1084/jem.20171450. Epub 2018 May 8.

5.

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.

Peterson CW, Wang J, Deleage C, Reddy S, Kaur J, Polacino P, Reik A, Huang ML, Jerome KR, Hu SL, Holmes MC, Estes JD, Kiem HP.

PLoS Pathog. 2018 Apr 19;14(4):e1006956. doi: 10.1371/journal.ppat.1006956. eCollection 2018 Apr.

6.

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.

Feder AF, Kline C, Polacino P, Cottrell M, Kashuba ADM, Keele BF, Hu SL, Petrov DA, Pennings PS, Ambrose Z.

PLoS Pathog. 2017 May 25;13(5):e1006358. doi: 10.1371/journal.ppat.1006358. eCollection 2017 May.

7.

Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation.

Peterson CW, Benne C, Polacino P, Kaur J, McAllister CE, Filali-Mouhim A, Obenza W, Pecor TA, Huang ML, Baldessari A, Murnane RD, Woolfrey AE, Jerome KR, Hu SL, Klatt NR, DeRosa S, Sékaly RP, Kiem HP.

JCI Insight. 2017 Feb 23;2(4):e91230. doi: 10.1172/jci.insight.91230.

8.

Design and In Vivo Characterization of Immunoconjugates Targeting HIV gp160.

Pincus SH, Song K, Maresh GA, Frank A, Worthylake D, Chung HK, Polacino P, Hamer DH, Coyne CP, Rosenblum MG, Marks JW, Chen G, Weiss D, Ghetie V, Vitetta ES, Robinson JE, Hu SL.

J Virol. 2017 Jan 18;91(3). pii: e01360-16. doi: 10.1128/JVI.01360-16. Print 2017 Feb 1.

9.

Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS.

Peterson CW, Haworth KG, Burke BP, Polacino P, Norman KK, Adair JE, Hu SL, Bartlett JS, Symonds GP, Kiem HP.

Mol Ther Methods Clin Dev. 2016 Feb 24;3:16007. doi: 10.1038/mtm.2016.7. eCollection 2016.

10.

Oral Immunization with Recombinant Vaccinia Virus Prime and Intramuscular Protein Boost Provides Protection against Intrarectal Simian-Human Immunodeficiency Virus Challenge in Macaques.

Thippeshappa R, Tian B, Cleveland B, Guo W, Polacino P, Hu SL.

Clin Vaccine Immunol. 2015 Dec 30;23(3):204-12. doi: 10.1128/CVI.00597-15.

11.

Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation.

Peterson CW, Haworth KG, Polacino P, Huang ML, Sykes C, Obenza WM, Repetto AC, Kashuba A, Bumgarner R, DeRosa SC, Woolfrey AE, Jerome KR, Mullins JI, Hu SL, Kiem HP.

AIDS. 2015 Aug 24;29(13):1597-606. doi: 10.1097/QAD.0000000000000702.

12.

Combinatorial hematopoietic stem cell transplantation and vaccination reduces viral pathogenesis following SHIV89.6P-challenge.

Younan PM, Polacino P, Kowalski JP, Hu SL, Kiem HP.

Gene Ther. 2015 Dec;22(12):1007-12. doi: 10.1038/gt.2015.83. Epub 2015 Sep 10.

PMID:
26355737
13.

Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates.

Younan PM, Peterson CW, Polacino P, Kowalski JP, Obenza W, Miller HW, Milless BP, Gafken P, DeRosa SC, Hu SL, Kiem HP.

Mol Ther. 2015 May;23(5):943-951. doi: 10.1038/mt.2015.19. Epub 2015 Feb 4.

14.

Dysregulation of multiple inflammatory molecules in lymph node and ileum of macaques during RT-SHIV infection with or without antiretroviral therapy.

Ambrose Z, Kline C, Polacino P, Hu SL.

J Med Primatol. 2014 Oct;43(5):298-309. doi: 10.1111/jmp.12126. Epub 2014 May 2.

15.

Robust suppression of env-SHIV viremia in Macaca nemestrina by 3-drug ART is independent of timing of initiation during chronic infection.

Peterson CW, Younan P, Polacino PS, Maurice NJ, Miller HW, Prlic M, Jerome KR, Woolfrey AE, Hu SL, Kiem HP.

J Med Primatol. 2013 Oct;42(5):237-46. doi: 10.1111/jmp.12060.

16.

Expression of the memory marker CD45RO on helper T cells in macaques.

Valentine M, Song K, Maresh GA, Mack H, Huaman MC, Polacino P, Ho O, Cristillo A, Kyung Chung H, Hu SL, Pincus SH.

PLoS One. 2013 Sep 4;8(9):e73969. doi: 10.1371/journal.pone.0073969. eCollection 2013.

17.

Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model.

Younan PM, Polacino P, Kowalski JP, Peterson CW, Maurice NJ, Williams NP, Ho O, Trobridge GD, Von Laer D, Prlic M, Beard BC, DeRosa S, Hu SL, Kiem HP.

Blood. 2013 Jul 11;122(2):179-87. doi: 10.1182/blood-2013-01-482224. Epub 2013 May 29.

18.

Peripheral blood invariant natural killer T cells of pig-tailed macaques.

Li X, Polacino P, Garcia-Navarro R, Hu SL, Tsuji M.

PLoS One. 2012;7(10):e48166. doi: 10.1371/journal.pone.0048166. Epub 2012 Oct 23.

19.

Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaques during disease progression analyzed by ultra-deep pyrosequencing.

Tso FY, Tully DC, Gonzalez S, Quince C, Ho O, Polacino P, Ruprecht RM, Hu SL, Wood C.

PLoS One. 2012;7(3):e32827. doi: 10.1371/journal.pone.0032827. Epub 2012 Mar 12.

20.

Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.

Lakhashe SK, Wang W, Siddappa NB, Hemashettar G, Polacino P, Hu SL, Villinger F, Else JG, Novembre FJ, Yoon JK, Lee SJ, Montefiori DC, Ruprecht RM, Rasmussen RA.

PLoS One. 2011;6(7):e22010. doi: 10.1371/journal.pone.0022010. Epub 2011 Jul 20.

21.

Vif substitution enables persistent infection of pig-tailed macaques by human immunodeficiency virus type 1.

Thippeshappa R, Polacino P, Yu Kimata MT, Siwak EB, Anderson D, Wang W, Sherwood L, Arora R, Wen M, Zhou P, Hu SL, Kimata JT.

J Virol. 2011 Apr;85(8):3767-79. doi: 10.1128/JVI.02438-10. Epub 2011 Feb 2.

22.

Pathogenic infection of Macaca nemestrina with a CCR5-tropic subtype-C simian-human immunodeficiency virus.

Ho O, Larsen K, Polacino P, Li Y, Anderson D, Song R, Ruprecht RM, Hu SL.

Retrovirology. 2009 Jul 14;6:65. doi: 10.1186/1742-4690-6-65.

23.

Differential pathogenicity of SHIV infection in pig-tailed and rhesus macaques.

Polacino P, Larsen K, Galmin L, Suschak J, Kraft Z, Stamatatos L, Anderson D, Barnett SW, Pal R, Bost K, Bandivdekar AH, Miller CJ, Hu SL.

J Med Primatol. 2008 Dec;37 Suppl 2:13-23. doi: 10.1111/j.1600-0684.2008.00325.x.

24.

Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses.

Kraft Z, Strouss K, Sutton WF, Cleveland B, Tso FY, Polacino P, Overbaugh J, Hu SL, Stamatatos L.

J Virol. 2008 Jun;82(12):5912-21. doi: 10.1128/JVI.00389-08. Epub 2008 Apr 9.

25.

Removal of a single N-linked glycan in human immunodeficiency virus type 1 gp120 results in an enhanced ability to induce neutralizing antibody responses.

Li Y, Cleveland B, Klots I, Travis B, Richardson BA, Anderson D, Montefiori D, Polacino P, Hu SL.

J Virol. 2008 Jan;82(2):638-51. Epub 2007 Oct 24.

26.

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.

Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M Jr, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, Hu SL, Coffin JM, Lifson JD, KewalRamani VN.

J Virol. 2007 Nov;81(22):12145-55. Epub 2007 Sep 12.

27.

Efficacy of a multigenic protein vaccine containing multimeric HIV gp160 against heterologous SHIV clade C challenges.

Rasmussen RA, Ong H, Song R, Chenine AL, Ayash-Rashkovsky M, Hu SL, Polacino P, Else JG, Novembre FJ, Ruprecht RM; Clade C Program Project.

AIDS. 2007 Sep 12;21(14):1841-8.

PMID:
17721091
28.

Immunogenicity and protective efficacy of Gag/Pol/Env vaccines derived from temporal isolates of SIVmne against cognate virus challenge.

Polacino P, Cleveland B, Zhu Y, Kimata JT, Overbaugh J, Anderson D, Hu SL.

J Med Primatol. 2007 Aug;36(4-5):254-65.

PMID:
17669214
29.

Evidence for persistent, occult infection in neonatal macaques following perinatal transmission of simian-human immunodeficiency virus SF162P3.

Jayaraman P, Zhu T, Misher L, Mohan D, Kuller L, Polacino P, Richardson BA, Bielefeldt-Ohmann H, Anderson D, Hu SL, Haigwood NL.

J Virol. 2007 Jan;81(2):822-34. Epub 2006 Nov 1.

30.

DNA prime/protein boost immunization against HIV clade C: safety and immunogenicity in mice.

Rasmussen RA, Ong H, Kittel C, Ruprecht CR, Ferrantelli F, Hu SL, Polacino P, McKenna J, Moon J, Travis B, Ruprecht RM.

Vaccine. 2006 Mar 20;24(13):2324-32. Epub 2005 Dec 19. Erratum in: Vaccine. 2006 Jun 5;24(23):5092. Policano, Patricia [corrected to Polacino, Patricia].

PMID:
16406147
31.

Perinatal transmission of SHIV-SF162P3 in Macaca nemestrina.

Jayaraman P, Mohan D, Polacino P, Kuller L, Sheikh N, Bielefeldt-Ohmann H, Richardson B, Anderson D, Hu SL, Haigwood NL.

J Med Primatol. 2004 Oct;33(5-6):243-50.

PMID:
15525325
32.

Persistence of low levels of simian immunodeficiency virus in macaques that were transiently viremic by conventional testing.

Zhu T, Hu SL, Feng F, Polacino P, Liu H, Hwangbo Y, Learn GH, Mullins JI, Corey L.

Virology. 2004 Jun 1;323(2):208-19.

33.

Human immunodeficiency virus type 2 DNA vaccine provides partial protection from acute baboon infection.

Locher CP, Witt SA, Ashlock BM, Polacino P, Hu SL, Shiboski S, Schmidt AM, Agy MB, Anderson DM, Staprans SI, zur Megede J, Levy JA.

Vaccine. 2004 Jun 2;22(17-18):2261-72.

PMID:
15149785
34.

Multigene DNA priming-boosting vaccines protect macaques from acute CD4+-T-cell depletion after simian-human immunodeficiency virus SHIV89.6P mucosal challenge.

Doria-Rose NA, Ohlen C, Polacino P, Pierce CC, Hensel MT, Kuller L, Mulvania T, Anderson D, Greenberg PD, Hu SL, Haigwood NL.

J Virol. 2003 Nov;77(21):11563-77.

35.

Multigene DNA prime-boost vaccines for SHIV89.6P.

Doria-Rose NA, Pierce CC, Hensel MT, Sutton WF, Sheikh N, Polacino P, Kuller L, Zhu YD, Hu SL, Anderson D, Haigwood NL.

J Med Primatol. 2003 Aug;32(4-5):218-28.

PMID:
14498982
36.

Role of immune responses against the envelope and the core antigens of simian immunodeficiency virus SIVmne in protection against homologous cloned and uncloned virus challenge in Macaques.

Polacino PS, Stallard V, Klaniecki JE, Pennathur S, Montefiori DC, Langlois AJ, Richardson BA, Morton WR, Benveniste RE, Hu SL.

J Virol. 1999 Oct;73(10):8201-15.

37.

Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines.

Polacino P, Stallard V, Montefiori DC, Brown CR, Richardson BA, Morton WR, Benveniste RE, Hu SL.

J Virol. 1999 Apr;73(4):3134-46.

38.

Limited breadth of the protective immunity elicited by simian immunodeficiency virus SIVmne gp160 vaccines in a combination immunization regimen.

Polacino P, Stallard V, Klaniecki JE, Montefiori DC, Langlois AJ, Richardson BA, Overbaugh J, Morton WR, Benveniste RE, Hu SL.

J Virol. 1999 Jan;73(1):618-30.

39.

Sequence diversity of SIV(Mne) Nef in vivo and in vitro.

Heidecker G, Muñoz H, Lloyd PA, Hodge DR, Pei GK, Rick SW, Brehm K, Ruscetti FW, Kuller L, Polacino P, Hu SL, Morton WR, Benveniste RE.

J Med Primatol. 1998 Apr-Jun;27(2-3):73-80.

PMID:
9747946
40.

Immunodeficiency virus cDNA synthesis in resting T lymphocytes is regulated by T cell activation signals and dendritic cells.

Polacino PS, Pinchuk LM, Sidorenko SP, Clark EA.

J Med Primatol. 1996 Jun;25(3):201-9.

PMID:
8892041
41.

Recombinant subunit vaccines as an approach to study correlates of protection against primate lentivirus infection.

Hu SL, Polacino P, Stallard V, Klaniecki J, Pennathur S, Travis BM, Misher L, Kornas H, Langlois AJ, Morton WR, Benveniste RE.

Immunol Lett. 1996 Jun;51(1-2):115-9.

PMID:
8811354
43.

Cell-cell interactions regulate dendritic cell-dependent HIV-1 production in CD4+ T lymphocytes.

Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, Clark EA.

Adv Exp Med Biol. 1995;378:461-3.

PMID:
8526118
44.

T-cell proliferation to subinfectious SIV correlates with lack of infection after challenge of macaques.

Clerici M, Clark EA, Polacino P, Axberg I, Kuller L, Casey NI, Morton WR, Shearer GM, Benveniste RE.

AIDS. 1994 Oct;8(10):1391-5.

PMID:
7818809
45.

Intrarectal inoculation of macaques by the simian immunodeficiency virus, SIVmne E11S: CD4+ depletion and AIDS.

Kuller L, Benveniste RE, Tsai CC, Clark EA, Polacino P, Watanabe R, Overbaugh J, Katze MG, Morton WR.

J Med Primatol. 1994 Sep;23(7):397-409.

PMID:
7731030
46.

The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection.

Pinchuk LM, Polacino PS, Agy MB, Klaus SJ, Clark EA.

Immunity. 1994 Jul;1(4):317-25.

PMID:
7534204
47.
48.

Detection of bovine herpesvirus-1 nucleic acid sequences, using a dot-blot hybridization procedure.

Andino RH, Torres HN, Polacino PS, Schudel A, Palma EL.

Am J Vet Res. 1987 Jun;48(6):984-7.

PMID:
3037953
49.

Biochemical characterization of a foot-and-mouth disease virus strain attenuated for cattle. Brief report.

Polacino P, Kaplan G, Yafal AG, Palma EL.

Arch Virol. 1986;88(1-2):143-50.

PMID:
3006639
50.

Homologous interference by a foot-and-mouth disease virus strain attenuated for cattle.

Polacino P, Kaplan G, Palma EL.

Arch Virol. 1985;86(3-4):291-301.

PMID:
2415086

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