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Items: 1 to 50 of 61

1.

Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation.

Díaz AF, Polo S, Gallardo N, Leánez S, Pol O.

J Clin Med. 2019 Jun 21;8(6). pii: E890. doi: 10.3390/jcm8060890.

2.

The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation.

Moreno P, Cazuza RA, Mendes-Gomes J, Díaz AF, Polo S, Leánez S, Leite-Panissi CRA, Pol O.

Int J Mol Sci. 2019 May 5;20(9). pii: E2211. doi: 10.3390/ijms20092211.

3.

Treatment With the Delta Opioid Agonist UFP-512 Alleviates Chronic Inflammatory and Neuropathic Pain: Mechanisms Implicated.

Polo S, Díaz AF, Gallardo N, Leánez S, Balboni G, Pol O.

Front Pharmacol. 2019 Mar 26;10:283. doi: 10.3389/fphar.2019.00283. eCollection 2019.

4.

Sulforaphane Inhibited the Nociceptive Responses, Anxiety- and Depressive-Like Behaviors Associated With Neuropathic Pain and Improved the Anti-allodynic Effects of Morphine in Mice.

Ferreira-Chamorro P, Redondo A, Riego G, Leánez S, Pol O.

Front Pharmacol. 2018 Nov 20;9:1332. doi: 10.3389/fphar.2018.01332. eCollection 2018.

5.

Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice.

Méndez-Lara KA, Santos D, Farré N, Ruiz-Nogales S, Leánez S, Sánchez-Quesada JL, Zapico E, Lerma E, Escolà-Gil JC, Blanco-Vaca F, Martín-Campos JM, Julve J, Pol O.

PLoS One. 2018 Oct 4;13(10):e0204841. doi: 10.1371/journal.pone.0204841. eCollection 2018.

6.
7.

The Inhibitory Effects of Cobalt Protoporphyrin IX and Cannabinoid 2 Receptor Agonists in Type 2 Diabetic Mice.

McDonnell C, Leánez S, Pol O.

Int J Mol Sci. 2017 Oct 28;18(11). pii: E2268. doi: 10.3390/ijms18112268.

8.

Treatment with Sulforaphane Produces Antinociception and Improves Morphine Effects during Inflammatory Pain in Mice.

Redondo A, Chamorro PAF, Riego G, Leánez S, Pol O.

J Pharmacol Exp Ther. 2017 Dec;363(3):293-302. doi: 10.1124/jpet.117.244376. Epub 2017 Sep 25.

PMID:
28947488
9.

Enhanced expression of heme oxygenase-1 in the locus coeruleus can be associated with anxiolytic-like effects.

Cazuza RA, Pol O, Leite-Panissi CRA.

Behav Brain Res. 2018 Jan 15;336:204-210. doi: 10.1016/j.bbr.2017.09.007. Epub 2017 Sep 5.

PMID:
28887196
10.

The induction of the transcription factor Nrf2 enhances the antinociceptive effects of delta-opioid receptors in diabetic mice.

McDonnell C, Leánez S, Pol O.

PLoS One. 2017 Jul 10;12(7):e0180998. doi: 10.1371/journal.pone.0180998. eCollection 2017.

11.

The role of carbon monoxide on the anti-nociceptive effects and expression of cannabinoid 2 receptors during painful diabetic neuropathy in mice.

Castany S, Carcolé M, Leánez S, Pol O.

Psychopharmacology (Berl). 2016 Jun;233(11):2209-2219. doi: 10.1007/s00213-016-4271-4. Epub 2016 Mar 29.

PMID:
27020787
12.

The antinociceptive effects of a δ-opioid receptor agonist in mice with painful diabetic neuropathy: Involvement of heme oxygenase 1.

Castany S, Carcolé M, Leánez S, Pol O.

Neurosci Lett. 2016 Feb 12;614:49-54. doi: 10.1016/j.neulet.2015.12.059. Epub 2016 Jan 4.

PMID:
26762785
13.

The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.

Castany S, Carcolé M, Leánez S, Pol O.

PLoS One. 2016 Jan 5;11(1):e0146427. doi: 10.1371/journal.pone.0146427. eCollection 2016.

14.

Treatment with a heme oxygenase 1 inducer enhances the antinociceptive effects of µ-opioid, δ-opioid, and cannabinoid 2 receptors during inflammatory pain.

Carcolé M, Castany S, Leánez S, Pol O.

J Pharmacol Exp Ther. 2014 Oct;351(1):224-32. doi: 10.1124/jpet.114.215681.

PMID:
25204546
15.

The role of gaseous neurotransmitters in the antinociceptive effects of morphine during acute thermal pain.

Gou G, Leánez S, Pol O.

Eur J Pharmacol. 2014 Aug 15;737:41-6. doi: 10.1016/j.ejphar.2014.05.004. Epub 2014 May 15.

PMID:
24846012
16.

Treatment with a carbon monoxide-releasing molecule inhibits chronic inflammatory pain in mice: nitric oxide contribution.

Negrete R, Hervera A, Leánez S, Pol O.

Psychopharmacology (Berl). 2014 Mar;231(5):853-61. doi: 10.1007/s00213-013-3302-7. Epub 2013 Oct 11.

PMID:
24114430
17.

Effects of treatment with a carbon monoxide-releasing molecule and a heme oxygenase 1 inducer in the antinociceptive effects of morphine in different models of acute and chronic pain in mice.

Hervera A, Gou G, Leánez S, Pol O.

Psychopharmacology (Berl). 2013 Aug;228(3):463-77. doi: 10.1007/s00213-013-3053-5. Epub 2013 Mar 13.

PMID:
23483201
18.

Treatment with carbon monoxide-releasing molecules and an HO-1 inducer enhances the effects and expression of µ-opioid receptors during neuropathic pain.

Hervera A, Leánez S, Motterlini R, Pol O.

Anesthesiology. 2013 May;118(5):1180-97. doi: 10.1097/ALN.0b013e318286d085.

PMID:
23358127
19.

Carbon monoxide reduces neuropathic pain and spinal microglial activation by inhibiting nitric oxide synthesis in mice.

Hervera A, Leánez S, Negrete R, Motterlini R, Pol O.

PLoS One. 2012;7(8):e43693. doi: 10.1371/journal.pone.0043693. Epub 2012 Aug 22.

20.

The inhibition of the nitric oxide-cGMP-PKG-JNK signaling pathway avoids the development of tolerance to the local antiallodynic effects produced by morphine during neuropathic pain.

Hervera A, Leánez S, Pol O.

Eur J Pharmacol. 2012 Jun 15;685(1-3):42-51. doi: 10.1016/j.ejphar.2012.04.009. Epub 2012 Apr 20.

PMID:
22546233
21.

The antinociceptive effects of JWH-015 in chronic inflammatory pain are produced by nitric oxide-cGMP-PKG-KATP pathway activation mediated by opioids.

Negrete R, Hervera A, Leánez S, Martín-Campos JM, Pol O.

PLoS One. 2011;6(10):e26688. doi: 10.1371/journal.pone.0026688. Epub 2011 Oct 21.

22.

Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling.

Hervera A, Negrete R, Leánez S, Martín-Campos JM, Pol O.

Mol Pain. 2011 Apr 12;7:25. doi: 10.1186/1744-8069-7-25.

23.

The spinal cord expression of neuronal and inducible nitric oxide synthases and their contribution in the maintenance of neuropathic pain in mice.

Hervera A, Negrete R, Leánez S, Martín-Campos JM, Pol O.

PLoS One. 2010 Dec 13;5(12):e14321. doi: 10.1371/journal.pone.0014321.

24.

The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice.

Hervera A, Negrete R, Leánez S, Martín-Campos J, Pol O.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):887-96. doi: 10.1124/jpet.110.167585. Epub 2010 May 24.

PMID:
20498253
25.

The peripheral administration of a nitric oxide donor potentiates the local antinociceptive effects of a DOR agonist during chronic inflammatory pain in mice.

Hervera A, Leánez S, Negrete R, Pol O.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Oct;380(4):345-52. doi: 10.1007/s00210-009-0436-6. Epub 2009 Jul 28.

PMID:
19636536
26.

Peripheral antinociceptive effects of mu- and delta-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain.

Leánez S, Hervera A, Pol O.

Eur J Pharmacol. 2009 Jan 5;602(1):41-9. doi: 10.1016/j.ejphar.2008.11.019. Epub 2008 Nov 18.

PMID:
19041302
28.

Tolerance to the antinociceptive and antiexudative effects of morphine in a murine model of peripheral inflammation.

Fernández-Dueñas V, Pol O, García-Nogales P, Hernández L, Planas E, Puig MM.

J Pharmacol Exp Ther. 2007 Jul;322(1):360-8. Epub 2007 Apr 27.

PMID:
17468301
29.

Expression of opioid receptors and c-fos in CB1 knockout mice exposed to neuropathic pain.

Pol O, Murtra P, Caracuel L, Valverde O, Puig MM, Maldonado R.

Neuropharmacology. 2006 Jan;50(1):123-32. Epub 2005 Dec 15.

PMID:
16360182
30.

Interaction between tramadol and two anti-emetics on nociception and gastrointestinal transit in mice.

Dürsteler C, Mases A, Fernandez V, Pol O, Puig MM.

Eur J Pain. 2006 Oct;10(7):629-38. Epub 2005 Nov 21.

PMID:
16300977
31.
32.

The involvement of nitric oxide in the enhanced expression of mu-opioid receptors during intestinal inflammation in mice.

Pol O, Sasaki M, Jiménez N, Dawson VL, Dawson TM, Puig MM.

Br J Pharmacol. 2005 Jul;145(6):758-66.

33.

Anti-exudative effects of opioid receptor agonists in a rat model of carrageenan-induced acute inflammation of the paw.

Romero A, Planas E, Poveda R, Sánchez S, Pol O, Puig MM.

Eur J Pharmacol. 2005 Mar 28;511(2-3):207-17.

PMID:
15792790
34.

Comparative assessment of the effects of alfentanil, esmolol or clonidine when used as adjuvants during induction of general anaesthesia.

Fernandez-Galinski S, Bermejo S, Mansilla R, Pol O, Puig MM.

Eur J Anaesthesiol. 2004 Jun;21(6):476-82.

PMID:
15248628
35.

Expression of opioid receptors during peripheral inflammation.

Pol O, Puig MM.

Curr Top Med Chem. 2004;4(1):51-61. Review.

PMID:
14754376
36.

Interaction between metamizol and tramadol in a model of acute visceral pain in rats.

Poveda R, Planas E, Pol O, Romero A, Sánchez S, Puig MM.

Eur J Pain. 2003;7(5):439-48.

PMID:
12935796
37.

The expression of delta- and kappa-opioid receptor is enhanced during intestinal inflammation in mice.

Pol O, Palacio JR, Puig MM.

J Pharmacol Exp Ther. 2003 Aug;306(2):455-62. Epub 2003 Apr 30.

PMID:
12724348
38.

Isoflurane requirements during combined general/epidural anesthesia for major abdominal surgery.

Casati L, Fernández-Galinski S, Barrera E, Pol O, Puig MM.

Anesth Analg. 2002 May;94(5):1331-7, table of contents.

PMID:
11973215
39.
40.

Inflammation enhances mu-opioid receptor transcription and expression in mice intestine.

Pol O, Alameda F, Puig MM.

Mol Pharmacol. 2001 Nov;60(5):894-9.

PMID:
11641416
41.

Intestinal inflammation enhances the inhibitory effects of opioids on intestinal permeability in mice.

Valle L, Pol O, Puig MM.

J Pharmacol Exp Ther. 2001 Feb;296(2):378-87.

PMID:
11160621
42.
43.

Antinociceptive/anti-edema effects of liposomal morphine during acute inflammation of the rat paw.

Planas E, Sánchez S, Rodriguez L, Pol O, Puig MM.

Pharmacology. 2000 Apr;60(3):121-7.

PMID:
10754448
44.
45.
46.

Peripheral effects of opioids in a model of chronic intestinal inflammation in mice.

Puig MM, Pol O.

J Pharmacol Exp Ther. 1998 Dec;287(3):1068-75.

PMID:
9864294
47.
48.

Peripheral effects of opioids in a model of intestinal inflammation in mice.

Pol O, Sanchez B, Puig MM.

Pharmacology. 1996 Dec;53(6):340-50.

PMID:
9032798
50.

Interaction of morphine and clonidine on gastrointestinal transit in mice.

Puig MM, Pol O, Warner W.

Anesthesiology. 1996 Dec;85(6):1403-12.

PMID:
8968188

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