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Items: 30

1.

Nitric oxide for inhalation in ST-elevation myocardial infarction (NOMI): a multicentre, double-blind, randomized controlled trial.

Janssens SP, Bogaert J, Zalewski J, Toth A, Adriaenssens T, Belmans A, Bennett J, Claus P, Desmet W, Dubois C, Goetschalckx K, Sinnaeve P, Vandenberghe K, Vermeersch P, Lux A, Szelid Z, Durak M, Lech P, Zmudka K, Pokreisz P, Vranckx P, Merkely B, Bloch KD, Van de Werf F; NOMI investigators .

Eur Heart J. 2018 Aug 1;39(29):2717-2725. doi: 10.1093/eurheartj/ehy232.

PMID:
29800130
2.

Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.

Heggermont WA, Papageorgiou AP, Quaegebeur A, Deckx S, Carai P, Verhesen W, Eelen G, Schoors S, van Leeuwen R, Alekseev S, Elzenaar I, Vinckier S, Pokreisz P, Walravens AS, Gijsbers R, Van Den Haute C, Nickel A, Schroen B, van Bilsen M, Janssens S, Maack C, Pinto Y, Carmeliet P, Heymans S.

Circulation. 2017 Aug 22;136(8):747-761. doi: 10.1161/CIRCULATIONAHA.116.024171. Epub 2017 Jun 13.

PMID:
28611091
3.

In Vivo Antitumoral Efficacy of PhAc-ALGP-Doxorubicin, an Enzyme-Activated Doxorubicin Prodrug, in Patient-Derived Soft Tissue Sarcoma Xenograft Models.

Cornillie J, Wozniak A, Pokreisz P, Casazza A, Vreys L, Wellens J, Vanleeuw U, Gebreyohannes YK, Debiec-Rychter M, Sciot R, Hompes D, Schöffski P.

Mol Cancer Ther. 2017 Aug;16(8):1566-1575. doi: 10.1158/1535-7163.MCT-16-0832. Epub 2017 May 31.

4.

Sustained Placental Growth Factor-2 Treatment Does Not Aggravate Advanced Atherosclerosis in Ischemic Cardiomyopathy.

Wu M, Pokreisz P, Swinnen M, Caluwe E, Gillijns H, Vanden Driessche N, Casazza A, Verbeken E, Collen D, Janssens S.

J Cardiovasc Transl Res. 2017 Aug;10(4):348-358. doi: 10.1007/s12265-017-9742-4. Epub 2017 Apr 10.

PMID:
28397162
5.

Carbon-11 and Fluorine-18 Radiolabeled Pyridopyrazinone Derivatives for Positron Emission Tomography (PET) Imaging of Phosphodiesterase-5 (PDE5).

Chekol R, Gheysens O, Ahamed M, Cleynhens J, Pokreisz P, Vanhoof G, Janssens S, Verbruggen A, Bormans G.

J Med Chem. 2017 Jan 12;60(1):486-496. doi: 10.1021/acs.jmedchem.6b01666. Epub 2016 Dec 23.

PMID:
28009175
6.

Neovascularization Potential of Blood Outgrowth Endothelial Cells From Patients With Stable Ischemic Heart Failure Is Preserved.

Dauwe D, Pelacho B, Wibowo A, Walravens AS, Verdonck K, Gillijns H, Caluwe E, Pokreisz P, van Gastel N, Carmeliet G, Depypere M, Maes F, Vanden Driessche N, Droogne W, Van Cleemput J, Vanhaecke J, Prosper F, Verfaillie C, Luttun A, Janssens S.

J Am Heart Assoc. 2016 Apr 18;5(4):e002288. doi: 10.1161/JAHA.115.002288.

7.

Concomitant Phosphodiesterase 5 Inhibition Enhances Myocardial Protection by Inhaled Nitric Oxide in Ischemia-Reperfusion Injury.

Lux A, Pokreisz P, Swinnen M, Caluwe E, Gillijns H, Szelid Z, Merkely B, Janssens SP.

J Pharmacol Exp Ther. 2016 Feb;356(2):284-92. doi: 10.1124/jpet.115.227850. Epub 2015 Nov 30.

PMID:
26621143
8.

Placental growth factor 2--A potential therapeutic strategy for chronic myocardial ischemia.

Wu M, Claus P, Vanden Driessche N, Reyns G, Pokreisz P, Gillijns H, Caluwe E, Bogaert J, Collen D, Janssens S.

Int J Cardiol. 2016 Jan 15;203:534-42. doi: 10.1016/j.ijcard.2015.10.177. Epub 2015 Oct 26.

PMID:
26569359
9.

Murine pressure overload models: a 30-MHz look brings a whole new "sound" into data interpretation.

Hermans H, Swinnen M, Pokreisz P, Caluwé E, Dymarkowski S, Herregods MC, Janssens S, Herijgers P.

J Appl Physiol (1985). 2014 Sep 1;117(5):563-71. doi: 10.1152/japplphysiol.00363.2014. Epub 2014 Jul 24.

10.

Evaluation of PET radioligands for in vivo visualization of phosphodiesterase 5 (PDE5).

Chekol R, Gheysens O, Cleynhens J, Pokreisz P, Vanhoof G, Ahamed M, Janssens S, Verbruggen A, Bormans G.

Nucl Med Biol. 2014 Feb;41(2):155-62. doi: 10.1016/j.nucmedbio.2013.10.007. Epub 2013 Oct 30.

PMID:
24290227
11.

Experimental model of transthoracic, vascular-targeted, photodynamically induced myocardial infarction.

Chrastina A, Pokreisz P, Schnitzer JE.

Am J Physiol Heart Circ Physiol. 2014 Jan 15;306(2):H270-8. doi: 10.1152/ajpheart.00818.2012. Epub 2013 Nov 8.

12.

Fetal rat hearts do not display acute cardiotoxicity in response to maternal Doxorubicin treatment.

Gziri MM, Pokreisz P, De Vos R, Verbeken E, Debiève F, Mertens L, Janssens SP, Amant F.

J Pharmacol Exp Ther. 2013 Sep;346(3):362-9. doi: 10.1124/jpet.113.205419. Epub 2013 Jun 21.

PMID:
23792410
13.

Increased cardiac myocyte PDE5 levels in human and murine pressure overload hypertrophy contribute to adverse LV remodeling.

Vandenwijngaert S, Pokreisz P, Hermans H, Gillijns H, Pellens M, Bax NA, Coppiello G, Oosterlinck W, Balogh A, Papp Z, Bouten CV, Bartunek J, D'hooge J, Luttun A, Verbeken E, Herregods MC, Herijgers P, Bloch KD, Janssens S.

PLoS One. 2013;8(3):e58841. doi: 10.1371/journal.pone.0058841. Epub 2013 Mar 18.

14.

Placental growth factor increases regional myocardial blood flow and contractile function in chronic myocardial ischemia.

Liu X, Claus P, Wu M, Reyns G, Verhamme P, Pokreisz P, Vandenwijngaert S, Dubois C, Vanhaecke J, Verbeken E, Bogaert J, Janssens S.

Am J Physiol Heart Circ Physiol. 2013 Mar 15;304(6):H885-94. doi: 10.1152/ajpheart.00587.2012. Epub 2013 Jan 11.

15.

Betaine homocysteine methyl transferase 1, a novel auto-antigen associated with anti-Golgi immune reactivity.

Van den Bergh K, Vercammen M, Regenass S, Derua R, Vermeersch P, Pokreisz P, Ocmant A, de Beéck KO, Janssens S, Waelkens E, Bossuyt X.

Clin Chim Acta. 2012 Jan 18;413(1-2):105-8. doi: 10.1016/j.cca.2011.09.001. Epub 2011 Sep 22.

PMID:
21963462
16.

Nitric oxide delays atrial tachycardia-induced electrical remodelling in a sheep model.

Lenaerts I, Holemans P, Pokreisz P, Sipido KR, Janssens S, Heidbüchel H, Willems R.

Europace. 2011 May;13(5):747-54. doi: 10.1093/europace/eur021. Epub 2011 Feb 4.

PMID:
21297123
17.

Differential effects of progenitor cell populations on left ventricular remodeling and myocardial neovascularization after myocardial infarction.

Dubois C, Liu X, Claus P, Marsboom G, Pokreisz P, Vandenwijngaert S, Dépelteau H, Streb W, Chaothawee L, Maes F, Gheysens O, Debyser Z, Gillijns H, Pellens M, Vandendriessche T, Chuah M, Collen D, Verbeken E, Belmans A, Van de Werf F, Bogaert J, Janssens S.

J Am Coll Cardiol. 2010 May 18;55(20):2232-43. doi: 10.1016/j.jacc.2009.10.081.

18.

Cardioselective nitric oxide synthase 3 gene transfer protects against myocardial reperfusion injury.

Szelid Z, Pokreisz P, Liu X, Vermeersch P, Marsboom G, Gillijns H, Pellens M, Verbeken E, Van de Werf F, Collen D, Janssens SP.

Basic Res Cardiol. 2010 Mar;105(2):169-79. doi: 10.1007/s00395-009-0077-4. Epub 2009 Dec 18.

PMID:
20020305
19.

Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

Vermeersch P, Buys E, Sips P, Pokreisz P, Marsboom G, Gillijns H, Pellens M, Dewerchin M, Bloch KD, Brouckaert P, Janssens S.

Open Cardiovasc Med J. 2009 Aug 31;3:98-104. doi: 10.2174/1874192400903010098.

20.

Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.

Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP.

Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12.

21.

Sustained endothelial progenitor cell dysfunction after chronic hypoxia-induced pulmonary hypertension.

Marsboom G, Pokreisz P, Gheysens O, Vermeersch P, Gillijns H, Pellens M, Liu X, Collen D, Janssens S.

Stem Cells. 2008 Apr;26(4):1017-26. doi: 10.1634/stemcells.2007-0562. Epub 2008 Feb 7.

22.

Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.

Liu X, Huang Y, Pokreisz P, Vermeersch P, Marsboom G, Swinnen M, Verbeken E, Santos J, Pellens M, Gillijns H, Van de Werf F, Bloch KD, Janssens S.

J Am Coll Cardiol. 2007 Aug 21;50(8):808-17. Epub 2007 Aug 6.

23.

Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia.

Vermeersch P, Buys E, Pokreisz P, Marsboom G, Ichinose F, Sips P, Pellens M, Gillijns H, Swinnen M, Graveline A, Collen D, Dewerchin M, Brouckaert P, Bloch KD, Janssens S.

Circulation. 2007 Aug 21;116(8):936-43. Epub 2007 Aug 6.

PMID:
17679618
24.

Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling.

Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim IH, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld AJ, Collen D, Busse R, Janssens S.

Hypertension. 2006 Apr;47(4):762-70. Epub 2006 Feb 27.

25.

Effect of adenovirus-mediated gene transfer of nitric oxide synthase on vascular reactivity of rat isolated pulmonary arteries.

Jiang L, Quarck R, Janssens S, Pokreisz P, Demedts M, Delcroix M.

Pflugers Arch. 2006 May;452(2):213-21. Epub 2006 Jan 11.

PMID:
16404609
26.

[Possibilities for cardiovascular gene therapy].

Szelid ZL, Pokreisz P, Janssens S, Polák G.

Orv Hetil. 2005 May 29;146(22):1189-96. Review. Hungarian.

PMID:
15997664
27.

Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.

Janssens S, Pokreisz P, Schoonjans L, Pellens M, Vermeersch P, Tjwa M, Jans P, Scherrer-Crosbie M, Picard MH, Szelid Z, Gillijns H, Van de Werf F, Collen D, Bloch KD.

Circ Res. 2004 May 14;94(9):1256-62. Epub 2004 Mar 25.

PMID:
15044322
28.

Preexisting antiadenoviral immunity and regional myocardial gene transfer: modulation by nitric oxide.

Szelid Z, Sinnaeve P, Vermeersch P, Gillijns H, Pellens M, Laurysens V, Van Pelt N, Flameng W, Sergeant P, Herijgers P, Pokreisz P, Van Zonneveld AJ, Verbeken E, Collen D, Janssens S.

Hum Gene Ther. 2002 Dec 10;13(18):2185-95.

PMID:
12542849
29.

Aerosol gene transfer with inducible nitric oxide synthase reduces hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats.

Budts W, Pokreisz P, Nong Z, Van Pelt N, Gillijns H, Gerard R, Lyons R, Collen D, Bloch KD, Janssens S.

Circulation. 2000 Dec 5;102(23):2880-5.

PMID:
11104748
30.

Effect of salt stress on fatty acid alterations in some strains of Dipodascopsis and Dipodascus spp.

Sajbidor J, Lamačka M, Breirerová E, Chrastina A, Pokreisz P, Certík M.

World J Microbiol Biotechnol. 1994 Mar;10(2):184-6. doi: 10.1007/BF00360883.

PMID:
24420943

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