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Items: 20


Pharmacologic Exhaustion of Suppressor Cells with Tasquinimod Enhances Bacterial Clearance during Tuberculosis.

Gupta S, Krug S, Pokkali S, Leanderson T, Isaacs JT, Srikrishna G, Bishai WR.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):386-389. doi: 10.1164/rccm.201805-0820LE. No abstract available.


Matrix Metalloproteinase Inhibition in a Murine Model of Cavitary Tuberculosis Paradoxically Worsens Pathology.

Ordonez AA, Pokkali S, Sanchez-Bautista J, Klunk MH, Urbanowski ME, K├╝bler A, Bishai WR, Elkington PT, Jain SK.

J Infect Dis. 2019 Jan 29;219(4):633-636. doi: 10.1093/infdis/jiy373.


Adjunct antibody administration with standard treatment reduces relapse rates in a murine tuberculosis model of necrotic granulomas.

Ordonez AA, Pokkali S, Kim S, Carr B, Klunk MH, Tong L, Saini V, Chang YS, McKevitt M, Smith V, Gossage DL, Jain SK.

PLoS One. 2018 May 14;13(5):e0197474. doi: 10.1371/journal.pone.0197474. eCollection 2018.


Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis.

Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR.

J Infect Dis. 2017 Jun 15;215(12):1883-1887. doi: 10.1093/infdis/jix208.


Novel interferon-gamma assays for diagnosing tuberculosis in young children in India.

Shaikh N, Gupte A, Dharmshale S, Pokkali S, Thakar M, Upadhye VJ, Ordonez AA, Kinikar A, Gupte N, Mave V, Kagal A, Gupta A, Lalvani A, Paranjpe R, Bharadwaj R, Jain SK.

Int J Tuberc Lung Dis. 2017 Apr 1;21(4):412-419. doi: 10.5588/ijtld.16.0428.


Microglia activation in a pediatric rabbit model of tuberculous meningitis.

Tucker EW, Pokkali S, Zhang Z, DeMarco VP, Klunk M, Smith ES, Ordonez AA, Penet MF, Bhujwalla Z, Jain SK, Kannan S.

Dis Model Mech. 2016 Dec 1;9(12):1497-1506.


A Systematic Approach for Developing Bacteria-Specific Imaging Tracers.

Ordonez AA, Weinstein EA, Bambarger LE, Saini V, Chang YS, DeMarco VP, Klunk MH, Urbanowski ME, Moulton KL, Murawski AM, Pokkali S, Kalinda AS, Jain SK.

J Nucl Med. 2017 Jan;58(1):144-150. doi: 10.2967/jnumed.116.181792. Epub 2016 Sep 15.


Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9.

Ordonez AA, Tasneen R, Pokkali S, Xu Z, Converse PJ, Klunk MH, Mollura DJ, Nuermberger EL, Jain SK.

Dis Model Mech. 2016 Jul 1;9(7):779-88. doi: 10.1242/dmm.025643. Epub 2016 May 26.


Imaging Chronic Tuberculous Lesions Using Sodium [(18)F]Fluoride Positron Emission Tomography in Mice.

Ordonez AA, DeMarco VP, Klunk MH, Pokkali S, Jain SK.

Mol Imaging Biol. 2015 Oct;17(5):609-14. doi: 10.1007/s11307-015-0836-6.


A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.

Dey B, Dey RJ, Cheung LS, Pokkali S, Guo H, Lee JH, Bishai WR.

Nat Med. 2015 Apr;21(4):401-6. doi: 10.1038/nm.3813. Epub 2015 Mar 2.


Radioiodinated DPA-713 imaging correlates with bactericidal activity of tuberculosis treatments in mice.

Ordonez AA, Pokkali S, DeMarco VP, Klunk M, Mease RC, Foss CA, Pomper MG, Jain SK.

Antimicrob Agents Chemother. 2015 Jan;59(1):642-9. doi: 10.1128/AAC.04180-14. Epub 2014 Nov 17.


Imaging Enterobacteriaceae infection in vivo with 18F-fluorodeoxysorbitol positron emission tomography.

Weinstein EA, Ordonez AA, DeMarco VP, Murawski AM, Pokkali S, MacDonald EM, Klunk M, Mease RC, Pomper MG, Jain SK.

Sci Transl Med. 2014 Oct 22;6(259):259ra146. doi: 10.1126/scitranslmed.3009815.


Novel vaccine strategies against tuberculosis: a road less travelled.

Pokkali S, Jain S.

Expert Rev Vaccines. 2013 Dec;12(12):1373-5. doi: 10.1586/14760584.2013.856766. No abstract available.


Vaccination with recombinant Mycobacterium tuberculosis PknD attenuates bacterial dissemination to the brain in guinea pigs.

Skerry C, Pokkali S, Pinn M, Be NA, Harper J, Karakousis PC, Jain SK.

PLoS One. 2013 Jun 11;8(6):e66310. doi: 10.1371/journal.pone.0066310. Print 2013.


Lipopolysaccharide inhibits Sindbis virus-induced IP-10 release in human peripheral blood mononuclear cells.

Dhanushkodi NR, Mohankumar V, Pokkali S, Raju R.

Viral Immunol. 2011 Jun;24(3):237-43. doi: 10.1089/vim.2010.0120.


Phenotypic modulation in Mycobacterium tuberculosis infected neutrophil during tuberculosis.

Pokkali S, Rajavelu P, Sudhakar R, Das SD.

Indian J Med Res. 2009 Aug;130(2):185-92.


Differential upregulation of chemokine receptors on CD56 NK cells and their transmigration to the site of infection in tuberculous pleurisy.

Pokkali S, Das SD, Selvaraj A.

FEMS Immunol Med Microbiol. 2009 Apr;55(3):352-60. doi: 10.1111/j.1574-695X.2008.00520.x. Epub 2009 Jan 12.


Augmented chemokine levels and chemokine receptor expression on immune cells during pulmonary tuberculosis.

Pokkali S, Das SD.

Hum Immunol. 2009 Feb;70(2):110-5. doi: 10.1016/j.humimm.2008.11.003. Epub 2008 Dec 25.


Comparative evaluation of cytokines, T-cell apoptosis, and costimulatory molecule expression in tuberculous and nontuberculous pleurisy.

Rajavelu P, Pokkali S, P U, Bhatt K, Narayanan PR, Salgame P, Das SD.

Clin Transl Sci. 2008 Dec;1(3):209-14. doi: 10.1111/j.1752-8062.2008.00057.x.


Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.

Pokkali S, Das SD, R L.

Cytokine. 2008 Mar;41(3):307-14. doi: 10.1016/j.cyto.2007.12.009. Epub 2008 Jan 28.


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