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Items: 38


Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses.

Ranjit S, Wong JY, Tan JW, Sin Tay C, Lee JM, Yin Han Wong K, Pojoga LH, Brooks DL, Garza AE, Maris SA, Katayama IA, Williams JS, Rivera A, Adler GK, Williams GH, Romero JR.

JCI Insight. 2019 Nov 1;4(21). pii: 129615. doi: 10.1172/jci.insight.129615.


Higher urinary cortisol levels associate with increased cardiovascular risk.

Haas AV, Hopkins PN, Brown NJ, Pojoga LH, Williams JS, Adler GK, Williams GH.

Endocr Connect. 2019 Jun 1;8(6):634-640. doi: 10.1530/EC-19-0182.


Aldosterone Modulates the Mechanistic Target of Rapamycin Signaling in Male Mice.

Brooks DL, Garza AE, Katayama IA, Romero JR, Adler GK, Pojoga LH, Williams GH.

Endocrinology. 2019 Apr 1;160(4):716-728. doi: 10.1210/en.2018-00989.


Histone demethylase LSD1 deficiency and biological sex: impact on blood pressure and aldosterone production.

Huang Y, Ting PY, Yao TM, Homma T, Brooks D, Katayama Rangel I, Adler GK, Romero JR, Williams JS, Pojoga LH, Williams GH.

J Endocrinol. 2019 Feb 1;240(2):111-122. doi: 10.1530/JOE-18-0247.


Biological Sex Modulates the Adrenal and Blood Pressure Responses to Angiotensin II.

Shukri MZ, Tan JW, Manosroi W, Pojoga LH, Rivera A, Williams JS, Seely EW, Adler GK, Jaffe IZ, Karas RH, Williams GH, Romero JR.

Hypertension. 2018 Jun;71(6):1083-1090. doi: 10.1161/HYPERTENSIONAHA.117.11087. Epub 2018 Apr 23.


Caloric restriction improves glucose homeostasis, yet increases cardiometabolic risk in caveolin-1-deficient mice.

Mayurasakorn K, Hasanah N, Homma T, Homma M, Rangel IK, Garza AE, Romero JR, Adler GK, Williams GH, Pojoga LH.

Metabolism. 2018 Jun;83:92-101. doi: 10.1016/j.metabol.2018.01.012. Epub 2018 Feb 2.


Combined Salt and Caloric Restrictions: Potential Adverse Outcomes.

Homma T, Homma M, Huang Y, Mayurasakorn K, Rodi NM, Hamid AAA, Hurwitz S, Yao T, Adler GK, Pojoga LH, Williams GH, Romero JR.

J Am Heart Assoc. 2017 Oct 11;6(10). pii: e005374. doi: 10.1161/JAHA.116.005374.


The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure.

Manosroi W, Tan JW, Rariy CM, Sun B, Goodarzi MO, Saxena AR, Williams JS, Pojoga LH, Lasky-Su J, Cui J, Guo X, Taylor KD, Chen YI, Xiang AH, Hsueh WA, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Seely EW.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4124-4135. doi: 10.1210/jc.2017-00957.


Regulation of aldosterone secretion by mineralocorticoid receptor-mediated signaling.

Chong C, Hamid A, Yao T, Garza AE, Pojoga LH, Adler GK, Romero JR, Williams GH.

J Endocrinol. 2017 Mar;232(3):525-534. doi: 10.1530/JOE-16-0452. Epub 2017 Jan 17.


Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis.

Baudrand R, Gupta N, Garza AE, Vaidya A, Leopold JA, Hopkins PN, Jeunemaitre X, Ferri C, Romero JR, Williams J, Loscalzo J, Adler GK, Williams GH, Pojoga LH.

J Am Heart Assoc. 2016 Sep 28;5(10). pii: e003845. doi: 10.1161/JAHA.116.003845.


A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics.

Baudrand R, Goodarzi MO, Vaidya A, Underwood PC, Williams JS, Jeunemaitre X, Hopkins PN, Brown N, Raby BA, Lasky-Su J, Adler GK, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Pojoga LH.

Metabolism. 2015 Dec;64(12):1674-81. doi: 10.1016/j.metabol.2015.09.005. Epub 2015 Sep 12.


Statin Use and Adrenal Aldosterone Production in Hypertensive and Diabetic Subjects.

Baudrand R, Pojoga LH, Vaidya A, Garza AE, Vöhringer PA, Jeunemaitre X, Hopkins PN, Yao TM, Williams J, Adler GK, Williams GH.

Circulation. 2015 Nov 10;132(19):1825-33. doi: 10.1161/CIRCULATIONAHA.115.016759. Epub 2015 Oct 2.


Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury.

Pojoga LH, Yao TM, Opsasnick LA, Siddiqui WT, Reslan OM, Adler GK, Williams GH, Khalil RA.

J Pharmacol Exp Ther. 2015 Oct;355(1):32-47. doi: 10.1124/jpet.115.226043. Epub 2015 Jul 16.


Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake.

Garza AE, Pojoga LH, Moize B, Hafiz WM, Opsasnick LA, Siddiqui WT, Horenstein M, Adler GK, Williams GH, Khalil RA.

Hypertension. 2015 Sep;66(3):674-80. doi: 10.1161/HYPERTENSIONAHA.115.05600. Epub 2015 Jul 13.


Variants in striatin gene are associated with salt-sensitive blood pressure in mice and humans.

Garza AE, Rariy CM, Sun B, Williams J, Lasky-Su J, Baudrand R, Yao T, Moize B, Hafiz WM, Romero JR, Adler GK, Ferri C, Hopkins PN, Pojoga LH, Williams GH.

Hypertension. 2015 Jan;65(1):211-217. doi: 10.1161/HYPERTENSIONAHA.114.04233. Epub 2014 Nov 3.


Aldosterone's rapid, nongenomic effects are mediated by striatin: a modulator of aldosterone's effect on estrogen action.

Coutinho P, Vega C, Pojoga LH, Rivera A, Prado GN, Yao TM, Adler G, Torres-Grajales M, Maldonado ER, Ramos-Rivera A, Williams JS, Williams G, Romero JR.

Endocrinology. 2014 Jun;155(6):2233-43. doi: 10.1210/en.2013-1834. Epub 2014 Mar 21.


Dissociation of hyperglycemia from altered vascular contraction and relaxation mechanisms in caveolin-1 null mice.

Pojoga LH, Yao TM, Opsasnick LA, Garza AE, Reslan OM, Adler GK, Williams GH, Khalil RA.

J Pharmacol Exp Ther. 2014 Feb;348(2):260-70. doi: 10.1124/jpet.113.209189. Epub 2013 Nov 26.


Aldosterone's mechanism of action: roles of lysine-specific demethylase 1, caveolin and striatin.

Baudrand R, Pojoga LH, Romero JR, Williams GH.

Curr Opin Nephrol Hypertens. 2014 Jan;23(1):32-7. doi: 10.1097/01.mnh.0000436543.48391.e0. Review.


Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.

Brown JM, Williams JS, Luther JM, Garg R, Garza AE, Pojoga LH, Ruan DT, Williams GH, Adler GK, Vaidya A.

Hypertension. 2014 Feb;63(2):273-80. doi: 10.1161/HYPERTENSIONAHA.113.01910. Epub 2013 Nov 4.


Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity.

Pojoga LH, Baudrand R, Adler GK.

Eur Heart J. 2013 Dec;34(45):3475-7. doi: 10.1093/eurheartj/eht158. Epub 2013 May 10. No abstract available.


Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice.

Chuengsamarn S, Garza AE, Krug AW, Romero JR, Adler GK, Williams GH, Pojoga LH.

Metabolism. 2013 Feb;62(2):275-81. doi: 10.1016/j.metabol.2012.07.013. Epub 2012 Sep 4.


Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension.

Williams JS, Chamarthi B, Goodarzi MO, Pojoga LH, Sun B, Garza AE, Raby BA, Adler GK, Hopkins PN, Brown NJ, Jeunemaitre X, Ferri C, Fang R, Leonor T, Cui J, Guo X, Taylor KD, Ida Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH, Shi Y.

Am J Hypertens. 2012 Jul;25(7):812-7. doi: 10.1038/ajh.2012.43. Epub 2012 Apr 26.


Activation of the mineralocorticoid receptor increases striatin levels.

Pojoga LH, Coutinho P, Rivera A, Yao TM, Maldonado ER, Youte R, Adler GK, Williams J, Turchin A, Williams GH, Romero JR.

Am J Hypertens. 2012 Feb;25(2):243-9. doi: 10.1038/ajh.2011.197. Epub 2011 Nov 17.


Histone demethylase LSD1 deficiency during high-salt diet is associated with enhanced vascular contraction, altered NO-cGMP relaxation pathway, and hypertension.

Pojoga LH, Williams JS, Yao TM, Kumar A, Raffetto JD, do Nascimento GR, Reslan OM, Adler GK, Williams GH, Shi Y, Khalil RA.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H1862-71. doi: 10.1152/ajpheart.00513.2011. Epub 2011 Aug 26.


Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension.

Pojoga LH, Underwood PC, Goodarzi MO, Williams JS, Adler GK, Jeunemaitre X, Hopkins PN, Raby BA, Lasky-Su J, Sun B, Cui J, Guo X, Taylor KD, Chen YD, Xiang A, Raffel LJ, Buchanan TA, Rotter JI, Williams GH.

J Clin Endocrinol Metab. 2011 Aug;96(8):E1288-92. doi: 10.1210/jc.2010-2738. Epub 2011 May 25.


Cell membrane-associated mineralocorticoid receptors? New evidence.

Krug AW, Pojoga LH, Williams GH, Adler GK.

Hypertension. 2011 Jun;57(6):1019-25. doi: 10.1161/HYPERTENSIONAHA.110.159459. Epub 2011 Apr 11. Review.


The influence of body mass index and renin-angiotensin-aldosterone system activity on the relationship between 25-hydroxyvitamin D and adiponectin in Caucasian men.

Vaidya A, Forman JP, Underwood PC, Hopkins PN, Williams GH, Pojoga LH, Williams JS.

Eur J Endocrinol. 2011 Jun;164(6):995-1002. doi: 10.1530/EJE-11-0025. Epub 2011 Mar 14.


The association of the angiotensinogen gene with insulin sensitivity in humans: a tagging single nucleotide polymorphism and haplotype approach.

Underwood PC, Sun B, Williams JS, Pojoga LH, Raby B, Lasky-Su J, Hunt S, Hopkins PN, Jeunemaitre X, Adler GK, Williams GH.

Metabolism. 2011 Aug;60(8):1150-7. doi: 10.1016/j.metabol.2010.12.009. Epub 2011 Feb 8.


The relationship between peroxisome proliferator-activated receptor-gamma and renin: a human genetics study.

Underwood PC, Sun B, Williams JS, Pojoga LH, Chamarthi B, Lasky-Su J, Raby BA, Hopkins PN, Jeunemaitre X, Brown NJ, Adler GK, Williams GH.

J Clin Endocrinol Metab. 2010 Sep;95(9):E75-9. doi: 10.1210/jc.2010-0270. Epub 2010 Jul 14.


Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice.

Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1776-88. doi: 10.1152/ajpheart.00661.2009. Epub 2010 Apr 2.


Caveolin-1 ablation reduces the adverse cardiovascular effects of N-omega-nitro-L-arginine methyl ester and angiotensin II.

Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH.

Endocrinology. 2010 Mar;151(3):1236-46. doi: 10.1210/en.2009-0514. Epub 2010 Jan 22.


Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice.

Pojoga LH, Yao TM, Sinha S, Ross RL, Lin JC, Raffetto JD, Adler GK, Williams GH, Khalil RA.

Am J Physiol Heart Circ Physiol. 2008 Mar;294(3):H1258-65. doi: 10.1152/ajpheart.01014.2007. Epub 2008 Jan 4.


Determination of ATP impurity in adenine dinucleotides.

Pojoga LH, Haghiac ML, Moose JE, Hilderman RH.

Nucleosides Nucleotides Nucleic Acids. 2004;23(3):581-98.


Characterization of the interaction of P1,P4-diadenosine 5'-tetraphosphate with luciferase.

Pojoga LH, Moose JE, Hilderman RH.

Biochem Biophys Res Commun. 2004 Mar 12;315(3):756-62.


A theoretical and experimental approach to the use of single wavelength calcium indicators.

Pojoga LH, Hilderman RH.

J Theor Biol. 2003 Apr 21;221(4):543-57.


Inhibition by adenine dinucleotides of ATP-induced prostacyclin release by bovine aortic endothelial cells.

Pojoga LH, Haghiac M, Hilderman RH.

Biochem Pharmacol. 2002 Aug 1;64(3):405-12.


P(1),P(4)-Diadenosine 5'-tetraphosphate modulates l-arginine and l-citrulline uptake by bovine aortic endothelial cells.

Hilderman RH, Casey TE, Pojoga LH.

Arch Biochem Biophys. 2000 Mar 1;375(1):124-30.


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