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Items: 1 to 50 of 764

1.

Autocrine GABA signaling distinctively regulates phenotypic activation of mouse pulmonary macrophages.

Januzi L, Poirier JW, Maksoud MJE, Xiang YY, Veldhuizen RAW, Gill SE, Cregan SP, Zhang H, Dekaban GA, Lu WY.

Cell Immunol. 2018 Jul 7. pii: S0008-8749(18)30306-X. doi: 10.1016/j.cellimm.2018.07.001. [Epub ahead of print]

PMID:
30017085
2.

Talazoparib is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts.

Laird JH, Lok BH, Ma J, Bell A, de Stanchina E, Poirier JT, Rudin CM.

Clin Cancer Res. 2018 Jun 26. pii: clincanres.0401.2018. doi: 10.1158/1078-0432.CCR-18-0401. [Epub ahead of print]

PMID:
29945991
3.

TLR4 Gene Expression and Pro-Inflammatory Cytokines in Alzheimer's Disease and in Response to Hippocampal Deafferentation in Rodents.

Miron J, Picard C, Frappier J, Dea D, Théroux L, Poirier J.

J Alzheimers Dis. 2018;63(4):1547-1556. doi: 10.3233/JAD-171160.

PMID:
29782315
4.

Brain properties predict proximity to symptom onset in sporadic Alzheimer's disease.

Vogel JW, Vachon-Presseau E, Pichet Binette A, Tam A, Orban P, La Joie R, Savard M, Picard C, Poirier J, Bellec P, Breitner JCS, Villeneuve S; Alzheimer’s Disease Neuroimaging Initiative* and the PREVENT-AD Research Group.

Brain. 2018 Jun 1;141(6):1871-1883. doi: 10.1093/brain/awy093.

5.

Bi-directional Association of Cerebrospinal Fluid Immune Markers with Stage of Alzheimer's Disease Pathogenesis.

Meyer PF, Savard M, Poirier J, Labonté A, Rosa-Neto P, Weitz TM, Town T, Breitner J; Alzheimer’s Disease Neuroimaging Initiative; PREVENT-AD Research Group.

J Alzheimers Dis. 2018;63(2):577-590. doi: 10.3233/JAD-170887.

6.

Loss-of-Function PCSK9 Mutations Are Not Associated With Alzheimer Disease.

Paquette M, Saavedra YGL, Poirier J, Théroux L, Dea D, Baass A, Dufour R.

J Geriatr Psychiatry Neurol. 2018 Mar;31(2):90-96. doi: 10.1177/0891988718764330. Epub 2018 Mar 21.

PMID:
29562810
7.

Acute cholecystitis: comparing clinical outcomes with TG13 severity and intended laparoscopic versus open cholecystectomy in difficult operative cases.

Gerard J, Luu MB, Poirier J, Deziel DJ.

Surg Endosc. 2018 Mar 9. doi: 10.1007/s00464-018-6134-z. [Epub ahead of print]

PMID:
29523984
8.

Alterations in cholesterol metabolism-related genes in sporadic Alzheimer's disease.

Picard C, Julien C, Frappier J, Miron J, Théroux L, Dea D; United Kingdom Brain Expression Consortium and for the Alzheimer's Disease Neuroimaging Initiative, Breitner JCS, Poirier J.

Neurobiol Aging. 2018 Jun;66:180.e1-180.e9. doi: 10.1016/j.neurobiolaging.2018.01.018. Epub 2018 Feb 9.

PMID:
29503034
9.

Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease.

Villeneuve S, Vogel JW, Gonneaud J, Pichet Binette A, Rosa-Neto P, Gauthier S, Bateman RJ, Fagan AM, Morris JC, Benzinger TLS, Johnson SC, Breitner JCS, Poirier J; Presymptomatic Evaluation of Novel or Experimental Treatments for Alzheimer Disease (PREVENT-AD) Research Group.

JAMA Neurol. 2018 May 1;75(5):608-619. doi: 10.1001/jamaneurol.2017.5135.

PMID:
29482212
10.

Isoprenoids and tau pathology in sporadic Alzheimer's disease.

Pelleieux S, Picard C, Lamarre-Théroux L, Dea D, Leduc V, Tsantrizos YS, Poirier J.

Neurobiol Aging. 2018 May;65:132-139. doi: 10.1016/j.neurobiolaging.2018.01.012. Epub 2018 Feb 2.

PMID:
29476987
11.

CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.

Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P; Alzheimer's Disease Neuroimaging Initiative.

Neurol Genet. 2018 Jan 30;4(1):e216. doi: 10.1212/NXG.0000000000000216. eCollection 2018 Feb.

12.

Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models.

Sharma SK, Chow A, Monette S, Vivier D, Pourat J, Edwards KJ, Dilling TR, Abdel-Atti D, Zeglis BM, Poirier JT, Lewis JS.

Cancer Res. 2018 Apr 1;78(7):1820-1832. doi: 10.1158/0008-5472.CAN-17-1958. Epub 2018 Jan 23.

PMID:
29363548
13.

CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease.

Miron J, Picard C, Nilsson N, Frappier J, Dea D, Théroux L; Alzheimer's Disease Neuroimaging Initiative; United Kingdom Brain Expression Consortium, Poirier J.

Alzheimers Dement. 2018 Jun;14(6):787-796. doi: 10.1016/j.jalz.2017.12.004. Epub 2018 Jan 19.

14.

Profiles of β-Amyloid Peptides and Key Secretases in Brain Autopsy Samples Differ with Sex and APOE ε4 Status: Impact for Risk and Progression of Alzheimer Disease.

Nyarko JNK, Quartey MO, Pennington PR, Heistad RM, Dea D, Poirier J, Baker GB, Mousseau DD.

Neuroscience. 2018 Mar 1;373:20-36. doi: 10.1016/j.neuroscience.2018.01.005. Epub 2018 Jan 11.

15.

Target engagement imaging of PARP inhibitors in small-cell lung cancer.

Carney B, Kossatz S, Lok BH, Schneeberger V, Gangangari KK, Pillarsetty NVK, Weber WA, Rudin CM, Poirier JT, Reiner T.

Nat Commun. 2018 Jan 12;9(1):176. doi: 10.1038/s41467-017-02096-w.

16.

Total Ossicular Replacement Prosthesis: A New Fat Interposition Technique.

Saliba I, Sabbah V, Poirier JB.

Clin Med Insights Ear Nose Throat. 2018 Jan 3;11:1179550617749614. doi: 10.1177/1179550617749614. eCollection 2018.

17.

Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease.

Konishi K, Joober R, Poirier J, MacDonald K, Chakravarty M, Patel R, Breitner J, Bohbot VD.

J Alzheimers Dis. 2018;61(4):1493-1507. doi: 10.3233/JAD-170540.

18.

Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease.

Tardif CL, Devenyi GA, Amaral RSC, Pelleieux S, Poirier J, Rosa-Neto P, Breitner J, Chakravarty MM; PREVENT-AD Research Group.

Hum Brain Mapp. 2018 Feb;39(2):971-984. doi: 10.1002/hbm.23897. Epub 2017 Nov 21.

PMID:
29164798
19.

CRISPR Libraries and Screening.

Poirier JT.

Prog Mol Biol Transl Sci. 2017;152:69-82. doi: 10.1016/bs.pmbts.2017.10.002. Epub 2017 Nov 6.

PMID:
29150005
20.

Effect of protected research time on ABSITE scores during general surgery residency.

Orkin BA, Poirier J, Kowal-Vern A, Chan E, Ohara K, Mendoza B.

Am J Surg. 2018 Feb;215(2):322-325. doi: 10.1016/j.amjsurg.2017.11.001. Epub 2017 Nov 3.

PMID:
29128101
21.

Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities.

Parent MJ, Zimmer ER, Shin M, Kang MS, Fonov VS, Mathieu A, Aliaga A, Kostikov A, Do Carmo S, Dea D, Poirier J, Soucy JP, Gauthier S, Cuello AC, Rosa-Neto P.

J Neurosci. 2017 Dec 13;37(50):12263-12271. doi: 10.1523/JNEUROSCI.1346-17.2017. Epub 2017 Nov 2.

22.

Deficit in Central Auditory Processing as a Biomarker of Pre-Clinical Alzheimer's Disease.

Tuwaig M, Savard M, Jutras B, Poirier J, Collins DL, Rosa-Neto P, Fontaine D, Breitner JCS; PREVENT-AD Research Group.

J Alzheimers Dis. 2017;60(4):1589-1600. doi: 10.3233/JAD-170545.

23.

Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.

Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas CJ, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T.

Nat Med. 2017 Nov;23(11):1362-1368. doi: 10.1038/nm.4407. Epub 2017 Oct 2.

24.

Familiarity deficits in cognitively normal aging individuals with APOE ε4: A follow-up investigation of medial temporal lobe structural correlates.

Schoemaker D, Poirier J, Collins DL, Gauthier S, Pruessner JC.

Alzheimers Dement (Amst). 2017 Jun 15;9:21-24. doi: 10.1016/j.dadm.2017.05.008. eCollection 2017.

25.

Manual Closed-Loop Insulin Delivery Using a Saddle Point Model Predictive Control Algorithm: Results of a Crossover Randomized Overnight Study.

Guilhem I, Penet M, Paillard A, Carpentier M, Esvant A, Lefebvre MA, Poirier JY.

J Diabetes Sci Technol. 2017 Sep;11(5):1007-1014. doi: 10.1177/1932296817717503. Epub 2017 Jul 5.

26.

Odor identification as a biomarker of preclinical AD in older adults at risk.

Lafaille-Magnan ME, Poirier J, Etienne P, Tremblay-Mercier J, Frenette J, Rosa-Neto P, Breitner JCS; PREVENT-AD Research Group.

Neurology. 2017 Jul 25;89(4):327-335. doi: 10.1212/WNL.0000000000004159. Epub 2017 Jun 28.

27.

Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus.

Miles LA, Burga LN, Gardner EE, Bostina M, Poirier JT, Rudin CM.

J Clin Invest. 2017 Aug 1;127(8):2957-2967. doi: 10.1172/JCI93472. Epub 2017 Jun 26.

28.

Unravelling the biology of SCLC: implications for therapy.

Sabari JK, Lok BH, Laird JH, Poirier JT, Rudin CM.

Nat Rev Clin Oncol. 2017 Sep;14(9):549-561. doi: 10.1038/nrclinonc.2017.71. Epub 2017 May 23. Review.

PMID:
28534531
29.

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer.

Sharma SK, Pourat J, Abdel-Atti D, Carlin SD, Piersigilli A, Bankovich AJ, Gardner EE, Hamdy O, Isse K, Bheddah S, Sandoval J, Cunanan KM, Johansen EB, Allaj V, Sisodiya V, Liu D, Zeglis BM, Rudin CM, Dylla SJ, Poirier JT, Lewis JS.

Cancer Res. 2017 Jul 15;77(14):3931-3941. doi: 10.1158/0008-5472.CAN-17-0299. Epub 2017 May 9.

30.

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG.

Mol Cancer Ther. 2017 Aug;16(8):1693-1704. doi: 10.1158/1535-7163.MCT-16-0821. Epub 2017 May 3.

PMID:
28468780
31.

Model Free iPID Control for Glycemia Regulation of Type-1 Diabetes.

MohammadRidha T, Ait-Ahmed M, Chaillous L, Krempf M, Guilhem I, Poirier JY, Moog CH.

IEEE Trans Biomed Eng. 2018 Jan;65(1):199-206. doi: 10.1109/TBME.2017.2698036. Epub 2017 Apr 25.

PMID:
28459682
32.

History of neurology: A desirable past?

Poirier J.

Rev Neurol (Paris). 2017 Apr;173(4):177-178. doi: 10.1016/j.neurol.2017.03.017. No abstract available.

PMID:
28457520
33.

Histone Code Aberrancies in Small Cell Lung Cancer.

Gardner EE, Poirier JT, Rudin CM.

J Thorac Oncol. 2017 Apr;12(4):599-601. doi: 10.1016/j.jtho.2017.02.008. No abstract available.

34.

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Gardner EE, Lok BH, Schneeberger VE, Desmeules P, Miles LA, Arnold PK, Ni A, Khodos I, de Stanchina E, Nguyen T, Sage J, Campbell JE, Ribich S, Rekhtman N, Dowlati A, Massion PP, Rudin CM, Poirier JT.

Cancer Cell. 2017 Feb 13;31(2):286-299. doi: 10.1016/j.ccell.2017.01.006.

35.

Common side closure type, but not stapler brand or oversewing, influences side-to-side anastomotic leak rates.

Fleetwood VA, Gross KN, Alex GC, Cortina CS, Smolevitz JB, Sarvepalli S, Bakhsh SR, Poirier J, Myers JA, Singer MA, Orkin BA.

Am J Surg. 2017 Mar;213(3):590-595. doi: 10.1016/j.amjsurg.2016.10.038. Epub 2017 Jan 13.

PMID:
28148456
36.

Small-cell lung cancer in 2016: Shining light on novel targets and therapies.

Rudin CM, Poirier JT.

Nat Rev Clin Oncol. 2017 Feb;14(2):75-76. doi: 10.1038/nrclinonc.2016.203. Epub 2016 Dec 13. No abstract available.

PMID:
27958293
37.

Multiple linear combination (MLC) regression tests for common variants adapted to linkage disequilibrium structure.

Yoo YJ, Sun L, Poirier JG, Paterson AD, Bull SB.

Genet Epidemiol. 2017 Feb;41(2):108-121. doi: 10.1002/gepi.22024. Epub 2016 Nov 25.

38.

Altered Episodic Memory in Introverted Young Adults Carrying the BDNFMet Allele.

Bombardier A, Beauchemin M, Gosselin N, Poirier J, De Beaumont L.

Int J Mol Sci. 2016 Nov 12;17(11). pii: E1886.

39.

Insulin Pump Failures: Has There Been an Improvement? Update of a Prospective Observational Study.

Guenego A, Bouzillé G, Breitel S, Esvant A, Poirier JY, Bonnet F, Guilhem I.

Diabetes Technol Ther. 2016 Dec;18(12):820-824. Epub 2016 Nov 11.

40.

The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder.

Gan-Or Z, Montplaisir JY, Ross JP, Poirier J, Warby SC, Arnulf I, Strong S, Dauvilliers Y, Leblond CS, Hu MTM, Högl B, Stefani A, Monaca CC, De Cock VC, Boivin M, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Barber TR, Evetts SG, Rolinski M, Dion PA, Desautels A, Gagnon JF, Dupré N, Postuma RB, Rouleau GA.

Neurobiol Aging. 2017 Jan;49:218.e13-218.e15. doi: 10.1016/j.neurobiolaging.2016.10.002. Epub 2016 Oct 13.

PMID:
27814994
41.

Implantable chemotherapy-loaded silk protein materials for neuroblastoma treatment.

Coburn J, Harris J, Zakharov AD, Poirier J, Ikegaki N, Kajdacsy-Balla A, Pilichowska M, Lyubimov AV, Shimada H, Kaplan DL, Chiu B.

Int J Cancer. 2017 Feb 1;140(3):726-735. doi: 10.1002/ijc.30479. Epub 2016 Nov 3.

42.

Utilization of Public Health Service Increased Risk Donors Yields Equivalent Outcomes in Liver Transplantation.

Fleetwood VA, Lusciks J, Poirier J, Hertl M, Chan EY.

J Transplant. 2016;2016:9658904. Epub 2016 Sep 29.

43.

The effect of tobacco use on outcomes of laparoscopic and open ventral hernia repairs: a review of the NSQIP dataset.

Kubasiak JC, Landin M, Schimpke S, Poirier J, Myers JA, Millikan KW, Luu MB.

Surg Endosc. 2017 Jun;31(6):2661-2666. doi: 10.1007/s00464-016-5280-4. Epub 2016 Oct 17.

PMID:
27752819
44.

BDNF Val66Met Polymorphism Influences Visuomotor Associative Learning and the Sensitivity to Action Observation.

Taschereau-Dumouchel V, Hétu S, Michon PE, Vachon-Presseau E, Massicotte E, De Beaumont L, Fecteau S, Poirier J, Mercier C, Chagnon YC, Jackson PL.

Sci Rep. 2016 Oct 5;6:34907. doi: 10.1038/srep34907.

45.

Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis.

Schneeberger VE, Allaj V, Gardner EE, Poirier JT, Rudin CM.

PLoS One. 2016 Sep 9;11(9):e0160587. doi: 10.1371/journal.pone.0160587. eCollection 2016.

46.

Extended Low-Dose Valganciclovir Is Effective Prophylaxis Against Cytomegalovirus in High-Risk Kidney Transplant Recipients With Near-Complete Eradication of Late-Onset Disease.

Fayek SA, Beshears E, Lieber R, Alvey N, Sauer A, Poirier J, Hollinger EF, Olaitan OK, Jensik S, Geyston J, Brokhof MM, Hodowanec AC, Hertl M, Simon DM.

Transplant Proc. 2016 Jul-Aug;48(6):2056-2064.e1. doi: 10.1016/j.transproceed.2016.05.004.

PMID:
27569944
47.

Butyrylcholinesterase K and Apolipoprotein E-ɛ4 Reduce the Age of Onset of Alzheimer's Disease, Accelerate Cognitive Decline, and Modulate Donepezil Response in Mild Cognitively Impaired Subjects.

De Beaumont L, Pelleieux S, Lamarre-Théroux L, Dea D, Poirier J; Alzheimer’s Disease Cooperative Study.

J Alzheimers Dis. 2016 Oct 4;54(3):913-922.

PMID:
27567841
48.

BDNF Val66Met Polymorphism Interacts with Sleep Consolidation to Predict Ability to Create New Declarative Memories.

Gosselin N, De Beaumont L, Gagnon K, Baril AA, Mongrain V, Blais H, Montplaisir J, Gagnon JF, Pelleieux S, Poirier J, Carrier J.

J Neurosci. 2016 Aug 10;36(32):8390-8. doi: 10.1523/JNEUROSCI.4432-15.2016.

49.

APOE2 Is Associated with Spatial Navigational Strategies and Increased Gray Matter in the Hippocampus.

Konishi K, Bhat V, Banner H, Poirier J, Joober R, Bohbot VD.

Front Hum Neurosci. 2016 Jul 13;10:349. doi: 10.3389/fnhum.2016.00349. eCollection 2016.

50.

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.

Lok BH, Gardner EE, Schneeberger VE, Ni A, Desmeules P, Rekhtman N, de Stanchina E, Teicher BA, Riaz N, Powell SN, Poirier JT, Rudin CM.

Clin Cancer Res. 2017 Jan 15;23(2):523-535. doi: 10.1158/1078-0432.CCR-16-1040. Epub 2016 Jul 20.

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