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Items: 36

1.

Screening and Antifungal Activity of a β-Carboline Derivative against Cryptococcus neoformans and C. gattii.

Cruz KS, Lima ES, da Silva MJA, de Souza ES, Montoia A, Pohlit AM, de Souza JVB.

Int J Microbiol. 2019 Jan 22;2019:7157845. doi: 10.1155/2019/7157845. eCollection 2019.

2.

Erratum to: Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory.

Vargas Fde S, Almeida PD, de Boleti AP, Pereira MM, de Souza TP, de Vasconcellos MC, Nunez CV, Pohlit AM, Lima ES.

BMC Complement Altern Med. 2016 Apr 14;16:119. doi: 10.1186/s12906-016-1097-x. No abstract available.

3.

Antioxidant activity and peroxidase inhibition of Amazonian plants extracts traditionally used as anti-inflammatory.

de Vargas FS, Almeida PD, de Boleti AP, Pereira MM, de Souza TP, de Vasconcellos MC, Nunez CV, Pohlit AM, Lima ES.

BMC Complement Altern Med. 2016 Feb 27;16:83. doi: 10.1186/s12906-016-1061-9. Erratum in: BMC Complement Altern Med. 2016;16:119.

4.

Anti-Toxoplasma Activity of Estragole and Thymol in Murine Models of Congenital and Noncongenital Toxoplasmosis.

Oliveira CB, Meurer YS, Medeiros TL, Pohlit AM, Silva MV, Mineo TW, Andrade-Neto VF.

J Parasitol. 2016 Jun;102(3):369-76. doi: 10.1645/15-848. Epub 2016 Feb 2.

PMID:
26836848
5.

In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon.

Lima RB, Rocha e Silva LF, Melo MR, Costa JS, Picanço NS, Lima ES, Vasconcellos MC, Boleti AP, Santos JM, Amorim RC, Chaves FC, Coutinho JP, Tadei WP, Krettli AU, Pohlit AM.

Malar J. 2015 Dec 18;14:508. doi: 10.1186/s12936-015-0999-2.

6.

Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives.

Carneiro PF, Pinto MCRF, Marra RKF, da Silva FC, Resende JALC, Rocha E Silva LF, Alves HG, Barbosa GS, de Vasconcellos MC, Lima ES, Pohlit AM, Ferreira VF.

Eur J Med Chem. 2016 Jan 27;108:134-140. doi: 10.1016/j.ejmech.2015.11.020. Epub 2015 Nov 27.

PMID:
26638044
7.

In vivo evaluation of isolated triterpenes and semi-synthetic derivatives as antimalarial agents.

Rocha E Silva LF, Ramalhete C, Nogueira KL, Mulhovo S, Ferreira MJ, Pohlit AM.

Eur J Med Chem. 2015 Sep 18;102:398-402. doi: 10.1016/j.ejmech.2015.08.022. Epub 2015 Aug 13.

PMID:
26301556
8.

An ethnobotanical study of anti-malarial plants among indigenous people on the upper Negro River in the Brazilian Amazon.

Frausin G, Hidalgo Ade F, Lima RB, Kinupp VF, Ming LC, Pohlit AM, Milliken W.

J Ethnopharmacol. 2015 Nov 4;174:238-52. doi: 10.1016/j.jep.2015.07.033. Epub 2015 Jul 26.

PMID:
26216513
9.

In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives.

Rocha e Silva LF, Nogueira KL, Pinto AC, Katzin AM, Sussmann RA, Muniz MP, de Andrade Neto VF, Chaves FC, Coutinho JP, Lima ES, Krettli AU, Tadei WP, Pohlit AM.

Antimicrob Agents Chemother. 2015;59(6):3271-80. doi: 10.1128/AAC.05012-14. Epub 2015 Mar 23.

10.

The quassinoid isobrucein B reduces inflammatory hyperalgesia and cytokine production by post-transcriptional modulation.

Silva RL, Lopes AH, França RO, Vieira SM, Silva EC, Amorim RC, Cunha FQ, Pohlit AM, Cunha TM.

J Nat Prod. 2015 Feb 27;78(2):241-9. doi: 10.1021/np500796f. Epub 2015 Feb 10.

PMID:
25667960
11.

In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production.

Pereira TB, Rocha E Silva LF, Amorim RC, Melo MR, Zacardi de Souza RC, Eberlin MN, Lima ES, Vasconcellos MC, Pohlit AM.

Malar J. 2014 Aug 13;13:317. doi: 10.1186/1475-2875-13-317.

12.

Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog.

Montoia A, Rocha E Silva LF, Torres ZE, Costa DS, Henrique MC, Lima ES, Vasconcellos MC, Souza RC, Costa MR, Grafov A, Grafova I, Eberlin MN, Tadei WP, Amorim RC, Pohlit AM.

Bioorg Med Chem Lett. 2014 Jun 15;24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. Epub 2014 Apr 28.

PMID:
24813729
13.

Gastro-protective effects of isobrucein B, a quassinoid isolated from Picrolemma sprucei.

Vieira SM, Silva RL, Lemos HP, Amorim RC, Silva EC, Reinach PS, Cunha FQ, Pohlit AM, Cunha TM.

Fitoterapia. 2014 Jun;95:8-15. doi: 10.1016/j.fitote.2014.02.008. Epub 2014 Mar 1.

PMID:
24594240
14.

Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads.

Pohlit AM, Lima RB, Frausin G, Silva LF, Lopes SC, Moraes CB, Cravo P, Lacerda MV, Siqueira AM, Freitas-Junior LH, Costa FT.

Molecules. 2013 Aug 2;18(8):9219-40. doi: 10.3390/molecules18089219. Review.

15.

In vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the Amazonian plant Tachia grandiflora (Gentianaceae).

Silva LF, Lima ES, Vasconcellos MC, Aranha ES, Costa DS, Mustafa EV, Morais SK, Alecrim Md, Nunomura SM, Struwe L, de Andrade-Neto VF, Pohlit AM.

Mem Inst Oswaldo Cruz. 2013 Jun;108(4):501-7. doi: 10.1590/S0074-02762013000400017.

16.

Chemical composition of Aspidosperma ulei Markgr. and antiplasmodial activity of selected indole alkaloids.

dos Santos Torres ZE, Silveira ER, Rocha e Silva LF, Lima ES, de Vasconcellos MC, de Andrade Uchoa DE, Filho RB, Pohlit AM.

Molecules. 2013 May 29;18(6):6281-97. doi: 10.3390/molecules18066281.

17.

Volatile Substances Produced by Fusarium oxysporum from Coffee Rhizosphere and Other Microbes affect Meloidogyne incognita and Arthrobotrys conoides.

Freire ES, Campos VP, Pinho RS, Oliveira DF, Faria MR, Pohlit AM, Noberto NP, Rezende EL, Pfenning LH, Silva JR.

J Nematol. 2012 Dec;44(4):321-8.

18.

Stability and antioxidant activity of semi-synthetic derivatives of 4-nerolidylcatechol.

Silva Lima E, Silva Pinto AC, Nogueira KL, Rocha e Silva LF, Oliveira de Almeida PD, Carvalho de Vasconcellos M, Chaves FC, Tadei WP, Pohlit AM.

Molecules. 2012 Dec 24;18(1):178-89. doi: 10.3390/molecules18010178.

19.

In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon.

Silva LF, Magalhães PM, Costa MR, Alecrim Md, Chaves FC, Hidalgo Ade F, Pohlit AM, Vieira PP.

Mem Inst Oswaldo Cruz. 2012 Nov;107(7):859-66.

20.

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog.

Rocha e Silva LF, Montoia A, Amorim RC, Melo MR, Henrique MC, Nunomura SM, Costa MR, Andrade Neto VF, Costa DS, Dantas G, Lavrado J, Moreira R, Paulo A, Pinto AC, Tadei WP, Zacardi RS, Eberlin MN, Pohlit AM.

Phytomedicine. 2012 Dec 15;20(1):71-6. doi: 10.1016/j.phymed.2012.09.008. Epub 2012 Oct 23.

21.

Antimalarial activity of ellipticine.

Pohlit AM, Rocha e Silva LF, Henrique MC, Montoia A, Amorim RC, Nunomura SM, Andrade-Neto VF.

Phytomedicine. 2012 Aug 15;19(11):1049. doi: 10.1016/j.phymed.2012.06.005. Epub 2012 Jul 26. No abstract available.

PMID:
22841488
22.

Involvement of intrinsic mitochondrial pathway in neosergeolide-induced apoptosis of human HL-60 leukemia cells: the role of mitochondrial permeability transition pore and DNA damage.

Cavalcanti BC, da Costa PM, Carvalho AA, Rodrigues FA, Amorim RC, Silva EC, Pohlit AM, Costa-Lotufo LV, Moraes MO, Pessoa C.

Pharm Biol. 2012 Aug;50(8):980-93. doi: 10.3109/13880209.2012.654921.

PMID:
22775415
23.

Concentration of Inorganic Elements Content in Benthic Seaweeds of Fernando de Noronha Archipelago by Synchrotron Radiation Total Reflection X-Ray Fluorescence Analysis (SRTXRF).

Ferreira Lde S, Lopes RP, Ulbrich MN, Guaratini T, Colepicolo P, Lopes NP, Garla RC, Oliveira Filho EC, Pohlit AM, Zucchi OL.

Int J Anal Chem. 2012;2012:407274. doi: 10.1155/2012/407274. Epub 2012 Feb 8.

24.

In vitro and in vivo antimalarial activity of essential oils and chemical components from three medicinal plants found in northeastern Brazil.

Mota ML, Lobo LT, Costa JM, Costa LS, Rocha HA, Rocha e Silva LF, Pohlit AM, Neto VF.

Planta Med. 2012 May;78(7):658-64. doi: 10.1055/s-0031-1298333. Epub 2012 Mar 22.

PMID:
22441836
25.

The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part II.

Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG.

Curr Med Chem. 2012;19(14):2176-228. Review.

PMID:
22414104
26.

The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases - part I.

Schmidt TJ, Khalid SA, Romanha AJ, Alves TM, Biavatti MW, Brun R, Da Costa FB, de Castro SL, Ferreira VF, de Lacerda MV, Lago JH, Leon LL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Scotti MT, Setzer WN, de N C Soeiro M, Steindel M, Tempone AG.

Curr Med Chem. 2012;19(14):2128-75. Review.

PMID:
22414103
27.

Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives.

Franco LL, de Almeida MV, E Silva LF, Vieira PP, Pohlit AM, Valle MS.

Chem Biol Drug Des. 2012 May;79(5):790-7. doi: 10.1111/j.1747-0285.2012.01345.x. Epub 2012 Mar 16.

PMID:
22284812
28.

Plant extracts, isolated phytochemicals, and plant-derived agents which are lethal to arthropod vectors of human tropical diseases--a review.

Pohlit AM, Rezende AR, Lopes Baldin EL, Lopes NP, Neto VF.

Planta Med. 2011 Apr;77(6):618-30. doi: 10.1055/s-0030-1270949. Epub 2011 Mar 22. Review.

PMID:
21432748
29.

Patent literature on mosquito repellent inventions which contain plant essential oils--a review.

Pohlit AM, Lopes NP, Gama RA, Tadei WP, Neto VF.

Planta Med. 2011 Apr;77(6):598-617. doi: 10.1055/s-0030-1270723. Epub 2011 Feb 15. Review.

PMID:
21328177
30.

In vivo and in vitro antimalarial activity of 4-nerolidylcatechol.

Rocha E Silva LF, Silva Pinto AC, Pohlit AM, Quignard EL, Vieira PP, Tadei WP, Chaves FC, Samonek JF, Lima CA, Costa MR, Alecrim Md, Andrade-Neto VF.

Phytother Res. 2011 Aug;25(8):1181-8. doi: 10.1002/ptr.3424. Epub 2011 Feb 8.

PMID:
21302338
31.

Piper peltatum: biomass and 4-nerolidylcatechol production.

Pinto AC, Chaves FC, dos Santos PA, Nunez CV, Tadei WP, Pohlit AM.

Planta Med. 2010 Sep;76(13):1473-6. doi: 10.1055/s-0029-1240938. Epub 2010 Mar 1.

PMID:
20195961
32.
33.

Biological activity of neosergeolide and isobrucein B (and two semi-synthetic derivatives) isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae).

Silva EC, Cavalcanti BC, Amorim RC, Lucena JF, Quadros DS, Tadei WP, Montenegro RC, Costa-Lotufo LV, Pessoa C, Moraes MO, Nunomura RC, Nunomura SM, Melo MR, Andrade-Neto VF, Silva LF, Vieira PP, Pohlit AM.

Mem Inst Oswaldo Cruz. 2009 Feb;104(1):48-56.

34.

New antimalarial and cytotoxic 4-nerolidylcatechol derivatives.

Pinto AC, Silva LF, Cavalcanti BC, Melo MR, Chaves FC, Lotufo LV, de Moraes MO, de Andrade-Neto VF, Tadei WP, Pessoa CO, Vieira PP, Pohlit AM.

Eur J Med Chem. 2009 Jun;44(6):2731-5. doi: 10.1016/j.ejmech.2008.10.025. Epub 2008 Oct 31.

PMID:
19084293
35.

Screening of Amazonian plants from the Adolpho Ducke forest reserve, Manaus, state of Amazonas, Brazil, for antimicrobial activity.

Carneiro AL, Teixeira MF, Oliveira VM, Fernandes OC, Cauper GS, Pohlit AM.

Mem Inst Oswaldo Cruz. 2008 Feb;103(1):31-8.

36.

In vitro inhibition of Plasmodium falciparum by substances isolated from Amazonian antimalarial plants.

de Andrade-Neto VF, Pohlit AM, Pinto AC, Silva EC, Nogueira KL, Melo MR, Henrique MC, Amorim RC, Silva LF, Costa MR, Nunomura RC, Nunomura SM, Alecrim WD, Alecrim Md, Chaves FC, Vieira PP.

Mem Inst Oswaldo Cruz. 2007 Jun;102(3):359-65.

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