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Items: 1 to 50 of 73

1.

Rapid Inhibition Profiling identifies a keystone target in the nucleotide biosynthesis pathway.

Peters CE, Lamsa A, Liu RB, Quach D, Sugie J, Brumage L, Pogliano J, Lopez-Garrido J, Pogliano K.

ACS Chem Biol. 2018 Aug 22. doi: 10.1021/acschembio.8b00273. [Epub ahead of print]

PMID:
30133247
2.

SCH79797 improves outcomes in experimental bacterial pneumonia by boosting neutrophil killing and direct antibiotic activity.

Gupta N, Liu R, Shin S, Sinha R, Pogliano J, Pogliano K, Griffin JH, Nizet V, Corriden R.

J Antimicrob Chemother. 2018 Jun 1;73(6):1586-1594. doi: 10.1093/jac/dky033.

PMID:
29514266
3.

Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies.

Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V.

Int J Antimicrob Agents. 2018 Mar;51(3):468-478. doi: 10.1016/j.ijantimicag.2017.12.032. Epub 2018 Jan 11. Review.

PMID:
29337066
4.

Phenotypic consequences of RNA polymerase dysregulation in Escherichia coli.

Sarkar P, Switzer A, Peters C, Pogliano J, Wigneshweraraj S.

Nucleic Acids Res. 2017 Nov 2;45(19):11131-11143. doi: 10.1093/nar/gkx733.

5.

Arylthiazole antibiotics targeting intracellular methicillin-resistant Staphylococcus aureus (MRSA) that interfere with bacterial cell wall synthesis.

Eid I, Elsebaei MM, Mohammad H, Hagras M, Peters CE, Hegazy YA, Cooper B, Pogliano J, Pogliano K, Abulkhair HS, Seleem MN, Mayhoub AS.

Eur J Med Chem. 2017 Oct 20;139:665-673. doi: 10.1016/j.ejmech.2017.08.039. Epub 2017 Aug 18.

6.

The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance.

Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V.

J Mol Med (Berl). 2017 Oct;95(10):1127-1136. doi: 10.1007/s00109-017-1579-4. Epub 2017 Aug 26.

7.

The Phage Nucleus and Tubulin Spindle Are Conserved among Large Pseudomonas Phages.

Chaikeeratisak V, Nguyen K, Egan ME, Erb ML, Vavilina A, Pogliano J.

Cell Rep. 2017 Aug 15;20(7):1563-1571. doi: 10.1016/j.celrep.2017.07.064.

8.

Bacteriological profiling of diphenylureas as a novel class of antibiotics against methicillin-resistant Staphylococcus aureus.

Mohammad H, Younis W, Ezzat HG, Peters CE, AbdelKhalek A, Cooper B, Pogliano K, Pogliano J, Mayhoub AS, Seleem MN.

PLoS One. 2017 Aug 10;12(8):e0182821. doi: 10.1371/journal.pone.0182821. eCollection 2017.

9.

Phenylthiazole Antibacterial Agents Targeting Cell Wall Synthesis Exhibit Potent Activity in Vitro and in Vivo against Vancomycin-Resistant Enterococci.

Mohammad H, Younis W, Chen L, Peters CE, Pogliano J, Pogliano K, Cooper B, Zhang J, Mayhoub A, Oldfield E, Cushman M, Seleem MN.

J Med Chem. 2017 Mar 23;60(6):2425-2438. doi: 10.1021/acs.jmedchem.6b01780. Epub 2017 Mar 15.

10.

Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones.

Döhrmann S, LaRock CN, Anderson EL, Cole JN, Ryali B, Stewart C, Nonejuie P, Pogliano J, Corriden R, Ghosh P, Nizet V.

Sci Rep. 2017 Feb 21;7:43039. doi: 10.1038/srep43039.

11.

Assembly of a nucleus-like structure during viral replication in bacteria.

Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J.

Science. 2017 Jan 13;355(6321):194-197. doi: 10.1126/science.aal2130.

12.

Classical β-Lactamase Inhibitors Potentiate the Activity of Daptomycin against Methicillin-Resistant Staphylococcus aureus and Colistin against Acinetobacter baumannii.

Sakoulas G, Rose W, Berti A, Olson J, Munguia J, Nonejuie P, Sakoulas E, Rybak MJ, Pogliano J, Nizet V.

Antimicrob Agents Chemother. 2017 Jan 24;61(2). pii: e01745-16. doi: 10.1128/AAC.01745-16. Print 2017 Feb.

13.

Cefazolin and Ertapenem, a Synergistic Combination Used To Clear Persistent Staphylococcus aureus Bacteremia.

Sakoulas G, Olson J, Yim J, Singh NB, Kumaraswamy M, Quach DT, Rybak MJ, Pogliano J, Nizet V.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6609-6618. doi: 10.1128/AAC.01192-16. Print 2016 Nov.

14.

Fosfomycin Enhances the Activity of Daptomycin against Vancomycin-Resistant Enterococci in an In Vitro Pharmacokinetic-Pharmacodynamic Model.

Hall Snyder AD, Werth BJ, Nonejuie P, McRoberts JP, Pogliano J, Sakoulas G, Yim J, Singh N, Rybak MJ.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5716-23. doi: 10.1128/AAC.00687-16. Print 2016 Oct.

15.

Rapid Inhibition Profiling in Bacillus subtilis to Identify the Mechanism of Action of New Antimicrobials.

Lamsa A, Lopez-Garrido J, Quach D, Riley EP, Pogliano J, Pogliano K.

ACS Chem Biol. 2016 Aug 19;11(8):2222-31. doi: 10.1021/acschembio.5b01050. Epub 2016 Jun 14.

16.

Bacterial Cytological Profiling (BCP) as a Rapid and Accurate Antimicrobial Susceptibility Testing Method for Staphylococcus aureus.

Quach DT, Sakoulas G, Nizet V, Pogliano J, Pogliano K.

EBioMedicine. 2016 Jan 18;4:95-103. doi: 10.1016/j.ebiom.2016.01.020. eCollection 2016 Feb.

17.

Standard susceptibility testing overlooks potent azithromycin activity and cationic peptide synergy against MDR Stenotrophomonas maltophilia.

Kumaraswamy M, Lin L, Olson J, Sun CF, Nonejuie P, Corriden R, Döhrmann S, Ali SR, Amaro D, Rohde M, Pogliano J, Sakoulas G, Nizet V.

J Antimicrob Chemother. 2016 May;71(5):1264-9. doi: 10.1093/jac/dkv487. Epub 2016 Jan 31.

18.

Application of bacterial cytological profiling to crude natural product extracts reveals the antibacterial arsenal of Bacillus subtilis.

Nonejuie P, Trial RM, Newton GL, Lamsa A, Ranmali Perera V, Aguilar J, Liu WT, Dorrestein PC, Pogliano J, Pogliano K.

J Antibiot (Tokyo). 2016 May;69(5):353-61. doi: 10.1038/ja.2015.116. Epub 2015 Dec 9.

19.

Penicillin Binding Protein 1 Is Important in the Compensatory Response of Staphylococcus aureus to Daptomycin-Induced Membrane Damage and Is a Potential Target for β-Lactam-Daptomycin Synergy.

Berti AD, Theisen E, Sauer JD, Nonejuie P, Olson J, Pogliano J, Sakoulas G, Nizet V, Proctor RA, Rose WE.

Antimicrob Agents Chemother. 2015 Nov 2;60(1):451-8. doi: 10.1128/AAC.02071-15. Print 2016 Jan.

20.

Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens.

Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H Jr, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V.

EBioMedicine. 2015 Jun 10;2(7):690-8. doi: 10.1016/j.ebiom.2015.05.021. eCollection 2015 Jul.

21.

Differential Effects of Penicillin Binding Protein Deletion on the Susceptibility of Enterococcus faecium to Cationic Peptide Antibiotics.

Sakoulas G, Kumaraswamy M, Nonejuie P, Werth BJ, Rybak MJ, Pogliano J, Rice LB, Nizet V.

Antimicrob Agents Chemother. 2015 Oct;59(10):6132-9. doi: 10.1128/AAC.00486-15. Epub 2015 Jul 20.

22.

In vitro activity of daptomycin in combination with β-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci.

Hindler JA, Wong-Beringer A, Charlton CL, Miller SA, Kelesidis T, Carvalho M, Sakoulas G, Nonejuie P, Pogliano J, Nizet V, Humphries R.

Antimicrob Agents Chemother. 2015 Jul;59(7):4279-88. doi: 10.1128/AAC.05077-14. Epub 2015 May 11.

23.

Best practices for fluorescence microscopy of the cyanobacterial circadian clock.

Cohen SE, Erb ML, Pogliano J, Golden SS.

Methods Enzymol. 2015;551:211-21. doi: 10.1016/bs.mie.2014.10.014. Epub 2014 Dec 26.

24.

Examining the use of ceftaroline in the treatment of Streptococcus pneumoniae meningitis with reference to human cathelicidin LL-37.

Sakoulas G, Nonejuie P, Kullar R, Pogliano J, Rybak MJ, Nizet V.

Antimicrob Agents Chemother. 2015 Apr;59(4):2428-31. doi: 10.1128/AAC.04965-14. Epub 2015 Jan 20.

25.

A bacteriophage tubulin harnesses dynamic instability to center DNA in infected cells.

Erb ML, Kraemer JA, Coker JK, Chaikeeratisak V, Nonejuie P, Agard DA, Pogliano J.

Elife. 2014 Nov 27;3. doi: 10.7554/eLife.03197.

26.

Ceftobiprole and ampicillin increase daptomycin susceptibility of daptomycin-susceptible and -resistant VRE.

Werth BJ, Barber KE, Tran KN, Nonejuie P, Sakoulas G, Pogliano J, Rybak MJ.

J Antimicrob Chemother. 2015 Feb;70(2):489-93. doi: 10.1093/jac/dku386. Epub 2014 Oct 9.

PMID:
25304643
27.

Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides.

Bayer AS, Mishra NN, Sakoulas G, Nonejuie P, Nast CC, Pogliano J, Chen KT, Ellison SN, Yeaman MR, Yang SJ.

Antimicrob Agents Chemother. 2014 Dec;58(12):7462-7. doi: 10.1128/AAC.03422-14. Epub 2014 Oct 6.

28.

Dynamic localization of the cyanobacterial circadian clock proteins.

Cohen SE, Erb ML, Selimkhanov J, Dong G, Hasty J, Pogliano J, Golden SS.

Curr Biol. 2014 Aug 18;24(16):1836-44. doi: 10.1016/j.cub.2014.07.036. Epub 2014 Aug 7.

29.

Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline.

Sakoulas G, Moise PA, Casapao AM, Nonejuie P, Olson J, Okumura CY, Rybak MJ, Kullar R, Dhand A, Rose WE, Goff DA, Bressler AM, Lee Y, Pogliano J, Johns S, Kaatz GW, Ebright JR, Nizet V.

Clin Ther. 2014 Oct 1;36(10):1317-33. doi: 10.1016/j.clinthera.2014.05.061. Epub 2014 Jul 10.

PMID:
25017183
30.

Potent synergy of ceftobiprole plus daptomycin against multiple strains of Staphylococcus aureus with various resistance phenotypes.

Barber KE, Werth BJ, Ireland CE, Stone NE, Nonejuie P, Sakoulas G, Pogliano J, Rybak MJ.

J Antimicrob Chemother. 2014 Nov;69(11):3006-10. doi: 10.1093/jac/dku236. Epub 2014 Jul 1.

PMID:
24990867
31.

Defining daptomycin resistance prevention exposures in vancomycin-resistant Enterococcus faecium and E. faecalis.

Werth BJ, Steed ME, Ireland CE, Tran TT, Nonejuie P, Murray BE, Rose WE, Sakoulas G, Pogliano J, Arias CA, Rybak MJ.

Antimicrob Agents Chemother. 2014 Sep;58(9):5253-61. doi: 10.1128/AAC.00098-14. Epub 2014 Jun 23.

32.

OmpA and OmpC are critical host factors for bacteriophage Sf6 entry in Shigella.

Parent KN, Erb ML, Cardone G, Nguyen K, Gilcrease EB, Porcek NB, Pogliano J, Baker TS, Casjens SR.

Mol Microbiol. 2014 Apr;92(1):47-60. doi: 10.1111/mmi.12536. Epub 2014 Mar 6.

33.

The structure and assembly mechanism of a novel three-stranded tubulin filament that centers phage DNA.

Zehr EA, Kraemer JA, Erb ML, Coker JK, Montabana EA, Pogliano J, Agard DA.

Structure. 2014 Apr 8;22(4):539-48. doi: 10.1016/j.str.2014.02.006. Epub 2014 Mar 13.

34.

Ceftaroline restores daptomycin activity against daptomycin-nonsusceptible vancomycin-resistant Enterococcus faecium.

Sakoulas G, Rose W, Nonejuie P, Olson J, Pogliano J, Humphries R, Nizet V.

Antimicrob Agents Chemother. 2014;58(3):1494-500. doi: 10.1128/AAC.02274-13. Epub 2013 Dec 23.

35.

Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus.

Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V.

J Mol Med (Berl). 2014 Feb;92(2):139-49. doi: 10.1007/s00109-013-1100-7. Epub 2013 Dec 3.

36.

Cytoskeletal proteins participate in conserved viral strategies across kingdoms of life.

Erb ML, Pogliano J.

Curr Opin Microbiol. 2013 Dec;16(6):786-9. doi: 10.1016/j.mib.2013.08.007. Epub 2013 Sep 19. Review.

PMID:
24055040
37.

Bacterial cytological profiling rapidly identifies the cellular pathways targeted by antibacterial molecules.

Nonejuie P, Burkart M, Pogliano K, Pogliano J.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16169-74. doi: 10.1073/pnas.1311066110. Epub 2013 Sep 17.

38.

Bacillus subtilis strain engineered for treatment of soil-transmitted helminth diseases.

Hu Y, Miller MM, Derman AI, Ellis BL, Monnerat RG, Pogliano J, Aroian RV.

Appl Environ Microbiol. 2013 Sep;79(18):5527-32. doi: 10.1128/AEM.01854-13. Epub 2013 Jul 8.

39.

Bacteriophage adhering to mucus provide a non-host-derived immunity.

Barr JJ, Auro R, Furlan M, Whiteson KL, Erb ML, Pogliano J, Stotland A, Wolkowicz R, Cutting AS, Doran KS, Salamon P, Youle M, Rohwer F.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10771-6. doi: 10.1073/pnas.1305923110. Epub 2013 May 20.

40.

Treatment of high-level gentamicin-resistant Enterococcus faecalis endocarditis with daptomycin plus ceftaroline.

Sakoulas G, Nonejuie P, Nizet V, Pogliano J, Crum-Cianflone N, Haddad F.

Antimicrob Agents Chemother. 2013 Aug;57(8):4042-5. doi: 10.1128/AAC.02481-12. Epub 2013 May 20.

41.

Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles.

Dedrick RM, Marinelli LJ, Newton GL, Pogliano K, Pogliano J, Hatfull GF.

Mol Microbiol. 2013 May;88(3):577-89. doi: 10.1111/mmi.12210. Epub 2013 Apr 8.

42.

Novel combinations of vancomycin plus ceftaroline or oxacillin against methicillin-resistant vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA.

Werth BJ, Vidaillac C, Murray KP, Newton KL, Sakoulas G, Nonejuie P, Pogliano J, Rybak MJ.

Antimicrob Agents Chemother. 2013 May;57(5):2376-9. doi: 10.1128/AAC.02354-12. Epub 2013 Feb 19.

43.

Ceftaroline increases membrane binding and enhances the activity of daptomycin against daptomycin-nonsusceptible vancomycin-intermediate Staphylococcus aureus in a pharmacokinetic/pharmacodynamic model.

Werth BJ, Sakoulas G, Rose WE, Pogliano J, Tewhey R, Rybak MJ.

Antimicrob Agents Chemother. 2013 Jan;57(1):66-73. doi: 10.1128/AAC.01586-12. Epub 2012 Oct 15. Erratum in: Antimicrob Agents Chemother. 2013 Mar;57(3):1565.

44.

A phage tubulin assembles dynamic filaments by an atypical mechanism to center viral DNA within the host cell.

Kraemer JA, Erb ML, Waddling CA, Montabana EA, Zehr EA, Wang H, Nguyen K, Pham DS, Agard DA, Pogliano J.

Cell. 2012 Jun 22;149(7):1488-99. doi: 10.1016/j.cell.2012.04.034.

45.

Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins.

Pogliano J, Pogliano N, Silverman JA.

J Bacteriol. 2012 Sep;194(17):4494-504. doi: 10.1128/JB.00011-12. Epub 2012 Jun 1.

46.

Alp7R regulates expression of the actin-like protein Alp7A in Bacillus subtilis.

Derman AI, Nonejuie P, Michel BC, Truong BD, Fujioka A, Erb ML, Pogliano J.

J Bacteriol. 2012 May;194(10):2715-24. doi: 10.1128/JB.06550-11. Epub 2012 Mar 16.

47.

Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycin-resistant Enterococcus faecium.

Sakoulas G, Bayer AS, Pogliano J, Tsuji BT, Yang SJ, Mishra NN, Nizet V, Yeaman MR, Moise PA.

Antimicrob Agents Chemother. 2012 Feb;56(2):838-44. doi: 10.1128/AAC.05551-11. Epub 2011 Nov 28.

48.

Cellular architecture mediates DivIVA ultrastructure and regulates min activity in Bacillus subtilis.

Eswaramoorthy P, Erb ML, Gregory JA, Silverman J, Pogliano K, Pogliano J, Ramamurthi KS.

MBio. 2011 Nov 22;2(6). pii: e00257-11. doi: 10.1128/mBio.00257-11. Print 2011.

49.

Isolation and characterization of a psychropiezophilic alphaproteobacterium.

Eloe EA, Malfatti F, Gutierrez J, Hardy K, Schmidt WE, Pogliano K, Pogliano J, Azam F, Bartlett DH.

Appl Environ Microbiol. 2011 Nov;77(22):8145-53. doi: 10.1128/AEM.05204-11. Epub 2011 Sep 23.

50.

Use of antistaphylococcal beta-lactams to increase daptomycin activity in eradicating persistent bacteremia due to methicillin-resistant Staphylococcus aureus: role of enhanced daptomycin binding.

Dhand A, Bayer AS, Pogliano J, Yang SJ, Bolaris M, Nizet V, Wang G, Sakoulas G.

Clin Infect Dis. 2011 Jul 15;53(2):158-63. doi: 10.1093/cid/cir340.

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