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Items: 32

1.

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation.

Davis RC, Marsden IT, Maloney MT, Minamide LS, Podlisny M, Selkoe DJ, Bamburg JR.

Mol Neurodegener. 2011 Jan 24;6:10. doi: 10.1186/1750-1326-6-10.

2.

The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.

Walsh DM, Klyubin I, Shankar GM, Townsend M, Fadeeva JV, Betts V, Podlisny MB, Cleary JP, Ashe KH, Rowan MJ, Selkoe DJ.

Biochem Soc Trans. 2005 Nov;33(Pt 5):1087-90. Review.

PMID:
16246051
3.

Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation.

Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, El Agnaf O, Hartley DM, Selkoe DJ.

J Neurosci. 2005 Mar 9;25(10):2455-62. Erratum in: J Neurosci. 2005 May 4;25(18):4658.

4.

Deciphering the genetic basis of Alzheimer's disease.

Selkoe DJ, Podlisny MB.

Annu Rev Genomics Hum Genet. 2002;3:67-99. Epub 2002 Apr 15. Review.

PMID:
12142353
5.

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain.

Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ.

Biochemistry. 2000 Sep 5;39(35):10831-9.

PMID:
10978169
6.

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation.

Qiu WQ, Walsh DM, Ye Z, Vekrellis K, Zhang J, Podlisny MB, Rosner MR, Safavi A, Hersh LB, Selkoe DJ.

J Biol Chem. 1998 Dec 4;273(49):32730-8.

7.

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

Podlisny MB, Walsh DM, Amarante P, Ostaszewski BL, Stimson ER, Maggio JE, Teplow DB, Selkoe DJ.

Biochemistry. 1998 Mar 17;37(11):3602-11.

PMID:
9521679
8.

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins.

Xia W, Zhang J, Kholodenko D, Citron M, Podlisny MB, Teplow DB, Haass C, Seubert P, Koo EH, Selkoe DJ.

J Biol Chem. 1997 Mar 21;272(12):7977-82.

9.

Presenilin proteins undergo heterogeneous endoproteolysis between Thr291 and Ala299 and occur as stable N- and C-terminal fragments in normal and Alzheimer brain tissue.

Podlisny MB, Citron M, Amarante P, Sherrington R, Xia W, Zhang J, Diehl T, Levesque G, Fraser P, Haass C, Koo EH, Seubert P, St George-Hyslop P, Teplow DB, Selkoe DJ.

Neurobiol Dis. 1997;3(4):325-37.

PMID:
9173929
10.

The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.

Walter J, Capell A, Gr├╝nberg J, Pesold B, Schindzielorz A, Prior R, Podlisny MB, Fraser P, Hyslop PS, Selkoe DJ, Haass C.

Mol Med. 1996 Nov;2(6):673-91.

11.

Protein topology of presenilin 1.

Doan A, Thinakaran G, Borchelt DR, Slunt HH, Ratovitsky T, Podlisny M, Selkoe DJ, Seeger M, Gandy SE, Price DL, Sisodia SS.

Neuron. 1996 Nov;17(5):1023-30.

12.

Diffuse plaques contain C-terminal A beta 42 and not A beta 40: evidence from cats and dogs.

Cummings BJ, Satou T, Head E, Milgram NW, Cole GM, Savage MJ, Podlisny MB, Selkoe DJ, Siman R, Greenberg BD, Cotman CW.

Neurobiol Aging. 1996 Jul-Aug;17(4):653-9.

PMID:
8832640
13.

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein.

Selkoe DJ, Yamazaki T, Citron M, Podlisny MB, Koo EH, Teplow DB, Haass C.

Ann N Y Acad Sci. 1996 Jan 17;777:57-64. Review.

PMID:
8624127
14.

Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture.

Podlisny MB, Ostaszewski BL, Squazzo SL, Koo EH, Rydell RE, Teplow DB, Selkoe DJ.

J Biol Chem. 1995 Apr 21;270(16):9564-70.

15.

Identification of amyloid beta protein in the brain of the small, short-lived lemurian primate Microcebus murinus.

Bons N, Mestre N, Ritchie K, Petter A, Podlisny M, Selkoe D.

Neurobiol Aging. 1994 Mar-Apr;15(2):215-20.

PMID:
7838294
16.

Passage of human amyloid beta-protein 1-40 across the murine blood-brain barrier.

Maness LM, Banks WA, Podlisny MB, Selkoe DJ, Kastin AJ.

Life Sci. 1994;55(21):1643-50.

PMID:
7968239
17.

Microinjection of synthetic amyloid beta-protein in monkey cerebral cortex fails to produce acute neurotoxicity.

Podlisny MB, Stephenson DT, Frosch MP, Tolan DR, Lieberburg I, Clemens JA, Selkoe DJ.

Am J Pathol. 1993 Jan;142(1):17-24.

18.

Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein.

Fraser PE, Nguyen JT, Inouye H, Surewicz WK, Selkoe DJ, Podlisny MB, Kirschner DA.

Biochemistry. 1992 Nov 10;31(44):10716-23.

PMID:
1420187
19.

Synthetic amyloid beta-protein fails to produce specific neurotoxicity in monkey cerebral cortex.

Podlisny MB, Stephenson DT, Frosch MP, Lieberburg I, Clemens JA, Selkoe DJ.

Neurobiol Aging. 1992 Sep-Oct;13(5):561-7.

PMID:
1281288
21.

Transforming growth factor-beta bound to soluble derivatives of the beta amyloid precursor protein of Alzheimer's disease.

Bodmer S, Podlisny MB, Selkoe DJ, Heid I, Fontana A.

Biochem Biophys Res Commun. 1990 Sep 14;171(2):890-7.

PMID:
2119582
22.

Detection of soluble forms of the beta-amyloid precursor protein in human plasma.

Podlisny MB, Mammen AL, Schlossmacher MG, Palmert MR, Younkin SG, Selkoe DJ.

Biochem Biophys Res Commun. 1990 Mar 30;167(3):1094-101.

PMID:
2138892
23.

Analysis of the beta-amyloid protein precursor of Alzheimer's disease: mRNAs and protein products.

Palmert MR, Podlisny MB, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, Gusella JF, Whitehouse PJ, Witker DS, Oltersdorf T, et al.

Adv Neurol. 1990;51:181-4. Review. No abstract available.

PMID:
2104687
24.

Molecular relation of amyloid filaments and paired helical filaments in Alzheimer's disease.

Selkoe DJ, Podlisny MB, Gronbeck A, Mammen A, Kosik KS.

Adv Neurol. 1990;51:171-9. Review. No abstract available.

PMID:
2104686
25.

Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein.

Palmert MR, Siedlak SL, Podlisny MB, Greenberg B, Shelton ER, Chan HW, Usiak M, Selkoe DJ, Perry G, Younkin SG.

Biochem Biophys Res Commun. 1989 Nov 30;165(1):182-8.

PMID:
2480122
26.

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.

Palmert MR, Podlisny MB, Witker DS, Oltersdorf T, Younkin LH, Selkoe DJ, Younkin SG.

Proc Natl Acad Sci U S A. 1989 Aug;86(16):6338-42.

27.

The beta amyloid protein precursor: mRNAs, membrane-associated forms, and soluble derivatives.

Palmert MR, Podlisny MB, Golde TE, Cohen ML, Kovacs DM, Tanzi RE, Gusella JF, Whitehouse PJ, Witker DS, Oltersdorf T, et al.

Prog Clin Biol Res. 1989;317:971-84. Review.

PMID:
2513588
28.

Antisera to an amino-terminal peptide detect the amyloid protein precursor of Alzheimer's disease and recognize senile plaques.

Palmert MR, Podlisny MB, Witker DS, Oltersdorf T, Younkin LH, Selkoe DJ, Younkin SG.

Biochem Biophys Res Commun. 1988 Oct 14;156(1):432-7.

PMID:
3140814
29.

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

Selkoe DJ, Podlisny MB, Joachim CL, Vickers EA, Lee G, Fritz LC, Oltersdorf T.

Proc Natl Acad Sci U S A. 1988 Oct;85(19):7341-5.

30.

Gene dosage of the amyloid beta precursor protein in Alzheimer's disease.

Podlisny MB, Lee G, Selkoe DJ.

Science. 1987 Oct 30;238(4827):669-71.

PMID:
2960019
31.

Conservation of brain amyloid proteins in aged mammals and humans with Alzheimer's disease.

Selkoe DJ, Bell DS, Podlisny MB, Price DL, Cork LC.

Science. 1987 Feb 20;235(4791):873-7.

PMID:
3544219
32.

Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease.

Selkoe DJ, Abraham CR, Podlisny MB, Duffy LK.

J Neurochem. 1986 Jun;46(6):1820-34.

PMID:
3517233

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