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Items: 15


A single nucleotide incorporation step limits human telomerase repeat addition activity.

Chen Y, Podlevsky JD, Logeswaran D, Chen JJ.

EMBO J. 2018 Mar 15;37(6). pii: e97953. doi: 10.15252/embj.201797953. Epub 2018 Feb 12.


Telomere biology and telomerase mutations in cirrhotic patients with hepatocellular carcinoma.

Donaires FS, Scatena NF, Alves-Paiva RM, Podlevsky JD, Logeswaran D, Santana BA, Teixeira AC, Chen JJ, Calado RT, Martinelli ALC.

PLoS One. 2017 Aug 16;12(8):e0183287. doi: 10.1371/journal.pone.0183287. eCollection 2017.


Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.

Stanley SE, Gable DL, Wagner CL, Carlile TM, Hanumanthu VS, Podlevsky JD, Khalil SE, DeZern AE, Rojas-Duran MF, Applegate CD, Alder JK, Parry EM, Gilbert WV, Armanios M.

Sci Transl Med. 2016 Aug 10;8(351):351ra107. doi: 10.1126/scitranslmed.aaf7837.


The functional requirement of two structural domains within telomerase RNA emerged early in eukaryotes.

Podlevsky JD, Li Y, Chen JJ.

Nucleic Acids Res. 2016 Nov 16;44(20):9891-9901. Epub 2016 Jul 4.


Evolutionary perspectives of telomerase RNA structure and function.

Podlevsky JD, Chen JJ.

RNA Biol. 2016 Aug 2;13(8):720-32. doi: 10.1080/15476286.2016.1205768. Epub 2016 Jun 30. Review.


Structure and function of echinoderm telomerase RNA.

Podlevsky JD, Li Y, Chen JJ.

RNA. 2016 Feb;22(2):204-15. doi: 10.1261/rna.053280.115. Epub 2015 Nov 23.


Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA.

Qi X, Rand DP, Podlevsky JD, Li Y, Mosig A, Stadler PF, Chen JJ.

Nat Commun. 2015 Jan 19;6:6105. doi: 10.1038/ncomms7105.


Telomerase mutations in smokers with severe emphysema.

Stanley SE, Chen JJ, Podlevsky JD, Alder JK, Hansel NN, Mathias RA, Qi X, Rafaels NM, Wise RA, Silverman EK, Barnes KC, Armanios M.

J Clin Invest. 2015 Feb;125(2):563-70. doi: 10.1172/JCI78554. Epub 2014 Dec 22.


A self-regulating template in human telomerase.

Brown AF, Podlevsky JD, Qi X, Chen Y, Xie M, Chen JJ.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11311-6. doi: 10.1073/pnas.1402531111. Epub 2014 Jun 30.


Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach.

Li Y, Podlevsky JD, Marz M, Qi X, Hoffmann S, Stadler PF, Chen JJ.

RNA. 2013 Jun;19(6):852-60. doi: 10.1261/rna.039131.113. Epub 2013 Apr 12.


The common ancestral core of vertebrate and fungal telomerase RNAs.

Qi X, Li Y, Honda S, Hoffmann S, Marz M, Mosig A, Podlevsky JD, Stadler PF, Selker EU, Chen JJ.

Nucleic Acids Res. 2013 Jan 7;41(1):450-62. doi: 10.1093/nar/gks980. Epub 2012 Oct 23.


It all comes together at the ends: telomerase structure, function, and biogenesis.

Podlevsky JD, Chen JJ.

Mutat Res. 2012 Feb 1;730(1-2):3-11. doi: 10.1016/j.mrfmmm.2011.11.002. Epub 2011 Nov 7. Review.


RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency.

Qi X, Xie M, Brown AF, Bley CJ, Podlevsky JD, Chen JJ.

EMBO J. 2012 Jan 4;31(1):150-61. doi: 10.1038/emboj.2011.363. Epub 2011 Oct 11.


A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity.

Xie M, Podlevsky JD, Qi X, Bley CJ, Chen JJ.

Nucleic Acids Res. 2010 Apr;38(6):1982-96. doi: 10.1093/nar/gkp1198. Epub 2009 Dec 30.


The telomerase database.

Podlevsky JD, Bley CJ, Omana RV, Qi X, Chen JJ.

Nucleic Acids Res. 2008 Jan;36(Database issue):D339-43. Epub 2007 Dec 11.

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