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Items: 41

1.

In Crystallo Selection to Establish New RNA Crystal Contacts.

Shoffner GM, Wang R, Podell E, Cech TR, Guo F.

Structure. 2018 Sep 4;26(9):1275-1283.e3. doi: 10.1016/j.str.2018.05.005. Epub 2018 Jun 14.

2.

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.

Schwartz JC, Podell ER, Han SS, Berry JD, Eggan KC, Cech TR.

Mol Biol Cell. 2014 Sep 1;25(17):2571-8. doi: 10.1091/mbc.E14-05-1007. Epub 2014 Jul 9.

3.

RNA seeds higher-order assembly of FUS protein.

Schwartz JC, Wang X, Podell ER, Cech TR.

Cell Rep. 2013 Nov 27;5(4):918-25. doi: 10.1016/j.celrep.2013.11.017. Epub 2013 Nov 21.

4.

FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2.

Schwartz JC, Ebmeier CC, Podell ER, Heimiller J, Taatjes DJ, Cech TR.

Genes Dev. 2012 Dec 15;26(24):2690-5. doi: 10.1101/gad.204602.112.

5.

Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.

Taylor DJ, Podell ER, Taatjes DJ, Cech TR.

J Mol Biol. 2011 Jul 1;410(1):10-7. doi: 10.1016/j.jmb.2011.04.049. Epub 2011 May 9.

6.

Functional interaction between telomere protein TPP1 and telomerase.

Zaug AJ, Podell ER, Nandakumar J, Cech TR.

Genes Dev. 2010 Mar 15;24(6):613-22. doi: 10.1101/gad.1881810.

7.

How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.

Nandakumar J, Podell ER, Cech TR.

Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):651-6. doi: 10.1073/pnas.0911099107. Epub 2009 Dec 22.

8.

Mutation in TERT separates processivity from anchor-site function.

Zaug AJ, Podell ER, Cech TR.

Nat Struct Mol Biol. 2008 Aug;15(8):870-2. doi: 10.1038/nsmb.1462. Epub 2008 Jul 20.

9.

Multiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundance.

Mozdy AD, Podell ER, Cech TR.

Mol Cell Biol. 2008 Jun;28(12):4152-61. doi: 10.1128/MCB.00512-08. Epub 2008 Apr 14.

10.

The POT1-TPP1 telomere complex is a telomerase processivity factor.

Wang F, Podell ER, Zaug AJ, Yang Y, Baciu P, Cech TR, Lei M.

Nature. 2007 Feb 1;445(7127):506-10. Epub 2007 Jan 21.

11.

A new model for Schizosaccharomyces pombe telomere recognition: the telomeric single-stranded DNA-binding activity of Pot11-389.

Croy JE, Podell ER, Wuttke DS.

J Mol Biol. 2006 Aug 4;361(1):80-93. Epub 2006 Jun 19. Erratum in: J Mol Biol. 2006 Oct 6;362(5):1181.

PMID:
16842820
12.

Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.

Jacobs SA, Podell ER, Cech TR.

Nat Struct Mol Biol. 2006 Mar;13(3):218-25. Epub 2006 Feb 5. Erratum in: Nat Struct Mol Biol. 2007 Oct;14(10):984.

PMID:
16462747
13.

Soluble domains of telomerase reverse transcriptase identified by high-throughput screening.

Jacobs SA, Podell ER, Wuttke DS, Cech TR.

Protein Sci. 2005 Aug;14(8):2051-8.

14.

Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.

Zaug AJ, Podell ER, Cech TR.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10864-9. Epub 2005 Jul 25.

15.

POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.

Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA.

J Biol Chem. 2005 Sep 16;280(37):32069-80. Epub 2005 Jul 18.

16.

Switching human telomerase on and off with hPOT1 protein in vitro.

Lei M, Zaug AJ, Podell ER, Cech TR.

J Biol Chem. 2005 May 27;280(21):20449-56. Epub 2005 Mar 24.

17.

Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection.

Lei M, Podell ER, Cech TR.

Nat Struct Mol Biol. 2004 Dec;11(12):1223-9. Epub 2004 Nov 21.

PMID:
15558049
18.

DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA.

Lei M, Podell ER, Baumann P, Cech TR.

Nature. 2003 Nov 13;426(6963):198-203.

PMID:
14614509
19.
20.
21.

Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.

Podell ER, Harrington DJ, Taatjes DJ, Koch TH.

Acta Crystallogr D Biol Crystallogr. 1999 Sep;55(Pt 9):1516-23.

PMID:
10489446
22.

A preorganized active site in the crystal structure of the Tetrahymena ribozyme.

Golden BL, Gooding AR, Podell ER, Cech TR.

Science. 1998 Oct 9;282(5387):259-64.

23.

Thermodynamic stability of the P4-P6 domain RNA tertiary structure measured by temperature gradient gel electrophoresis.

Szewczak AA, Podell ER, Bevilacqua PC, Cech TR.

Biochemistry. 1998 Aug 11;37(32):11162-70.

PMID:
9698362
24.

Crystals by design: a strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron.

Golden BL, Podell ER, Gooding AR, Cech TR.

J Mol Biol. 1997 Aug 1;270(5):711-23.

PMID:
9245599
25.

X-ray crystallography of large RNAs: heavy-atom derivatives by RNA engineering.

Golden BL, Gooding AR, Podell ER, Cech TR.

RNA. 1996 Dec;2(12):1295-305.

26.

RNA tertiary structure mediation by adenosine platforms.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1696-9.

PMID:
8781229
27.

Crystal structure of a group I ribozyme domain: principles of RNA packing.

Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA.

Science. 1996 Sep 20;273(5282):1678-85.

PMID:
8781224
28.

Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis. 1988.

Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH.

Nutrition. 1995 Mar-Apr;11(2):181; discussion 180, 182. No abstract available.

PMID:
7647490
29.

Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.

Lindenbaum J, Healton EB, Savage DG, Brust JC, Garrett TJ, Podell ER, Marcell PD, Stabler SP, Allen RH.

N Engl J Med. 1988 Jun 30;318(26):1720-8.

PMID:
3374544
30.
31.
32.

Assay of methylmalonic acid in the serum of patients with cobalamin deficiency using capillary gas chromatography-mass spectrometry.

Stabler SP, Marcell PD, Podell ER, Allen RH, Lindenbaum J.

J Clin Invest. 1986 May;77(5):1606-12.

33.

Cobalamin malabsorption in three siblings due to an abnormal intrinsic factor that is markedly susceptible to acid and proteolysis.

Yang YM, Ducos R, Rosenberg AJ, Catrou PG, Levine JS, Podell ER, Allen RH.

J Clin Invest. 1985 Dec;76(6):2057-65.

34.
35.

Measurements of iron absorption from prenatal multivitamin--mineral supplements.

Seligman PA, Caskey JH, Frazier JL, Zucker RM, Podell ER, Allen RH.

Obstet Gynecol. 1983 Mar;61(3):356-62.

PMID:
6823378
36.

Presence and formation of cobalamin analogues in multivitamin-mineral pills.

Kondo H, Binder MJ, Kolhouse JF, Smythe WR, Podell ER, Allen RH.

J Clin Invest. 1982 Oct;70(4):889-98.

37.

Nitrous oxide has multiple deleterious effects on cobalamin metabolism and causes decreases in activities of both mammalian cobalamin-dependent enzymes in rats.

Kondo H, Osborne ML, Kolhouse JF, Binder MJ, Podell ER, Utley CS, Abrams RS, Allen RH.

J Clin Invest. 1981 May;67(5):1270-83.

38.

Development of a dual label Schilling test for pancreatic exocrine function based on the differential absorption of cobalamin bound to intrinsic factor and R protein.

Brugge WR, Goff JS, Allen NC, Podell ER, Allen RH.

Gastroenterology. 1980 May;78(5 Pt 1):937-49. No abstract available.

PMID:
7380200
39.

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