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Bone turnover markers during the remission phase in children and adolescents with type 1 diabetes.

Madsen JOB, Herskin CW, Zerahn B, Jensen AK, Jørgensen NR, Olsen BS, Svensson J, Pociot F, Johannesen J.

Pediatr Diabetes. 2019 Dec 15. doi: 10.1111/pedi.12963. [Epub ahead of print]


Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining.

Kirk IK, Simon C, Banasik K, Holm PC, Haue AD, Jensen PB, Juhl Jensen L, Rodríguez CL, Pedersen MK, Eriksson R, Andersen HU, Almdal T, Bork-Jensen J, Grarup N, Borch-Johnsen K, Pedersen O, Pociot F, Hansen T, Bergholdt R, Rossing P, Brunak S.

Elife. 2019 Dec 10;8. pii: e44941. doi: 10.7554/eLife.44941.


Unaffected bone mineral density in Danish children and adolescents with type 1 diabetes.

Madsen JOB, Herskin CW, Zerahn B, Jensen AK, Jørgensen NR, Olsen BS, Pociot F, Johannesen J.

J Bone Miner Metab. 2019 Nov 21. doi: 10.1007/s00774-019-01058-0. [Epub ahead of print]


Breast Milk-Derived Extracellular Vesicles Enriched in Exosomes From Mothers With Type 1 Diabetes Contain Aberrant Levels of microRNAs.

Mirza AH, Kaur S, Nielsen LB, Størling J, Yarani R, Roursgaard M, Mathiesen ER, Damm P, Svare J, Mortensen HB, Pociot F.

Front Immunol. 2019 Oct 25;10:2543. doi: 10.3389/fimmu.2019.02543. eCollection 2019.


Perinatal Whole Blood Zinc Status and Cytokines, Adipokines, and Other Immune Response Proteins.

Kyvsgaard JN, Ellervik C, Lindkvist EB, Pipper CB, Pociot F, Svensson J, Thorsen SU.

Nutrients. 2019 Aug 22;11(9). pii: E1980. doi: 10.3390/nu11091980.


Bone turnover markers in children and adolescents with type 1 diabetes-A systematic review.

Madsen JOB, Jørgensen NR, Pociot F, Johannesen J.

Pediatr Diabetes. 2019 Aug;20(5):510-522. doi: 10.1111/pedi.12853. Epub 2019 May 22. Review.


Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins.

Thorsen SU, Pipper CB, Ellervik C, Pociot F, Kyvsgaard JN, Svensson J.

Nutrients. 2019 Mar 4;11(3). pii: E543. doi: 10.3390/nu11030543.


Plasma lipid species at type 1 diabetes onset predict residual beta-cell function after 6 months.

Overgaard AJ, Weir JM, Jayawardana K, Mortensen HB, Pociot F, Meikle PJ.

Metabolomics. 2018 Dec 4;14(12):158. doi: 10.1007/s11306-018-1456-3.


miRNA-27a-3p and miRNA-222-3p as Novel Modulators of Phosphodiesterase 3a (PDE3A) in Cerebral Microvascular Endothelial Cells.

Yasmeen S, Kaur S, Mirza AH, Brodin B, Pociot F, Kruuse C.

Mol Neurobiol. 2019 Aug;56(8):5304-5314. doi: 10.1007/s12035-018-1446-5. Epub 2019 Jan 2.


The emerging role of lncRNAs in inflammatory bowel disease.

Yarani R, Mirza AH, Kaur S, Pociot F.

Exp Mol Med. 2018 Dec 6;50(12):161. doi: 10.1038/s12276-018-0188-9. Review.


Cell Type-Selective Expression of Circular RNAs in Human Pancreatic Islets.

Kaur S, Mirza AH, Pociot F.

Noncoding RNA. 2018 Nov 27;4(4). pii: E38. doi: 10.3390/ncrna4040038.


Influence of Disease Duration on Circulating Levels of miRNAs in Children and Adolescents with New Onset Type 1 Diabetes.

Samandari N, Mirza AH, Kaur S, Hougaard P, Nielsen LB, Fredheim S, Mortensen HB, Pociot F.

Noncoding RNA. 2018 Nov 21;4(4). pii: E35. doi: 10.3390/ncrna4040035.


Capturing residual beta cell function in type 1 diabetes.

Pociot F.

Diabetologia. 2019 Jan;62(1):28-32. doi: 10.1007/s00125-018-4768-y. Epub 2018 Nov 3.


MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.

Lindeløv Vestergaard A, Heiner Bang-Berthelsen C, Fløyel T, Lucien Stahl J, Christen L, Taheri Sotudeh F, de Hemmer Horskjær P, Stensgaard Frederiksen K, Greek Kofod F, Bruun C, Adrian Berchtold L, Størling J, Regazzi R, Kaur S, Pociot F, Mandrup-Poulsen T.

PLoS One. 2018 Sep 27;13(9):e0203713. doi: 10.1371/journal.pone.0203713. eCollection 2018.


Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model.

Nielsen KO, Jacobsen KS, Mirza AH, Winther TN, Størling J, Glebe D, Pociot F, Hogh B.

Exp Cell Res. 2018 Oct 1;371(1):92-103. doi: 10.1016/j.yexcr.2018.07.044. Epub 2018 Jul 27.


Hepatitis B virus suppresses the secretion of insulin-like growth factor binding protein 1 to facilitate anti-apoptotic IGF-1 effects in HepG2 cells.

Nielsen KO, Mirza AH, Kaur S, Jacobsen KS, Winther TN, Glebe D, Pociot F, Hogh B, Størling J.

Exp Cell Res. 2018 Sep 15;370(2):399-408. doi: 10.1016/j.yexcr.2018.07.002. Epub 2018 Jul 4.


Abnormal islet sphingolipid metabolism in type 1 diabetes.

Holm LJ, Krogvold L, Hasselby JP, Kaur S, Claessens LA, Russell MA, Mathews CE, Hanssen KF, Morgan NG, Koeleman BPC, Roep BO, Gerling IC, Pociot F, Dahl-Jørgensen K, Buschard K.

Diabetologia. 2018 Jul;61(7):1650-1661. doi: 10.1007/s00125-018-4614-2. Epub 2018 Apr 18.


Type 1 diabetes genome-wide association studies: not to be lost in translation.

Pociot F.

Clin Transl Immunology. 2017 Dec 1;6(12):e162. doi: 10.1038/cti.2017.51. eCollection 2017 Dec. Review.


'25-Hydroxyvitamin D, Autoantigenic and Total Antibody Concentrations: Results from a Danish Case-control Study of Newly Diagnosed Patients with Childhood Type 1 Diabetes and their Healthy Siblings'.

Thorsen SU, Pipper CB, Johannesen J, Mortensen HB, Pociot F, Svensson J.

Scand J Immunol. 2018 Jan;87(1):46-53. doi: 10.1111/sji.12632. Epub 2017 Dec 12.


High Neonatal Blood Iron Content Is Associated with the Risk of Childhood Type 1 Diabetes Mellitus.

Kyvsgaard JN, Overgaard AJ, Thorsen SU, Hansen TH, Pipper CB, Mortensen HB, Pociot F, Svensson J.

Nutrients. 2017 Nov 6;9(11). pii: E1221. doi: 10.3390/nu9111221.


Long non-coding RNAs as novel players in β cell function and type 1 diabetes.

Mirza AH, Kaur S, Pociot F.

Hum Genomics. 2017 Jul 24;11(1):17. doi: 10.1186/s40246-017-0113-7. Review.


The identification and functional annotation of RNA structures conserved in vertebrates.

Seemann SE, Mirza AH, Hansen C, Bang-Berthelsen CH, Garde C, Christensen-Dalsgaard M, Torarinsson E, Yao Z, Workman CT, Pociot F, Nielsen H, Tommerup N, Ruzzo WL, Gorodkin J.

Genome Res. 2017 Aug;27(8):1371-1383. doi: 10.1101/gr.208652.116. Epub 2017 May 9.


Pannexin-2-deficiency sensitizes pancreatic β-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo.

Berchtold LA, Miani M, Diep TA, Madsen AN, Cigliola V, Colli M, Krivokapic JM, Pociot F, Eizirik DL, Meda P, Holst B, Billestrup N, Størling J.

Mol Cell Endocrinol. 2017 Jun 15;448:108-121. doi: 10.1016/j.mce.2017.04.001. Epub 2017 Apr 5.


25-Hydroxyvitamin D and Peripheral Immune Mediators: Results from Two Nationwide Danish Pediatric Cohorts.

Thorsen SU, Pipper CB, Skogstrand K, Pociot F, Svensson J.

Nutrients. 2017 Apr 6;9(4). pii: E365. doi: 10.3390/nu9040365.


Type 1 Diabetes Candidate Genes Linked to Pancreatic Islet Cell Inflammation and Beta-Cell Apoptosis.

Størling J, Pociot F.

Genes (Basel). 2017 Feb 16;8(2). pii: E72. doi: 10.3390/genes8020072. Review.


Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts.

Kang W, Bang-Berthelsen CH, Holm A, Houben AJ, Müller AH, Thymann T, Pociot F, Estivill X, Friedländer MR.

RNA. 2017 Apr;23(4):433-445. doi: 10.1261/rna.059725.116. Epub 2017 Jan 6.


Low perinatal zinc status is not associated with the risk of type 1 diabetes in children.

Kyvsgaard JN, Overgaard AJ, Jacobsen LD, Thorsen SU, Pipper CB, Hansen TH, Husted S, Mortensen HB, Pociot F, Svensson J.

Pediatr Diabetes. 2017 Nov;18(7):637-642. doi: 10.1111/pedi.12476. Epub 2016 Nov 22.


Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study.

Thorsen SU, Pipper CB, Eising S, Skogstrand K, Hougaard DM, Svensson J, Pociot F.

Clin Immunol. 2017 Jan;174:18-23. doi: 10.1016/j.clim.2016.11.007. Epub 2016 Nov 15.


Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus.

Samandari N, Mirza AH, Nielsen LB, Kaur S, Hougaard P, Fredheim S, Mortensen HB, Pociot F.

Diabetologia. 2017 Feb;60(2):354-363. doi: 10.1007/s00125-016-4156-4. Epub 2016 Nov 19.


Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study.

Thorsen SU, Pipper CB, Mortensen HB, Skogstrand K, Pociot F, Johannesen J, Svensson J; Danish Childhood Diabetes Register.

Pediatr Diabetes. 2017 Dec;18(8):749-754. doi: 10.1111/pedi.12464. Epub 2016 Nov 10.


No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study.

Thorsen SU, Pipper CB, Mortensen HB, Pociot F, Johannesen J, Svensson J.

Int J Endocrinol. 2016;2016:8350158. Epub 2016 Oct 13.


Metabolomic Biomarkers in the Progression to Type 1 Diabetes.

Overgaard AJ, Kaur S, Pociot F.

Curr Diab Rep. 2016 Dec;16(12):127. Review.


GLP-1 Induces Barrier Protective Expression in Brunner's Glands and Regulates Colonic Inflammation.

Bang-Berthelsen CH, Holm TL, Pyke C, Simonsen L, Søkilde R, Pociot F, Heller RS, Folkersen L, Kvist PH, Jackerott M, Fleckner J, Vilién M, Knudsen LB, Heding A, Frederiksen KS.

Inflamm Bowel Dis. 2016 Sep;22(9):2078-97. doi: 10.1097/MIB.0000000000000847.


Effects of the genome on immune regulation in type 1 diabetes.

Pociot F, Kaur S, Nielsen LB.

Pediatr Diabetes. 2016 Jul;17 Suppl 22:37-42. doi: 10.1111/pedi.12336.


Potential beneficial effects of a gluten-free diet in newly diagnosed children with type 1 diabetes: a pilot study.

Svensson J, Sildorf SM, Pipper CB, Kyvsgaard JN, Bøjstrup J, Pociot FM, Mortensen HB, Buschard K.

Springerplus. 2016 Jul 7;5(1):994. doi: 10.1186/s40064-016-2641-3. eCollection 2016.


A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells.

Vestergaard AL, Blankestijn M, Stahl JL, Pallesen EM, Bang-Berthelsen CH, Pociot F, Novotny GW, Lundh M, Mandrup-Poulsen T.

Int J Mol Sci. 2016 Jun 7;17(6). pii: E896. doi: 10.3390/ijms17060896.


Genetic risk factors for type 1 diabetes.

Pociot F, Lernmark Å.

Lancet. 2016 Jun 4;387(10035):2331-2339. doi: 10.1016/S0140-6736(16)30582-7. Review.


Neonatal vitamin D status is not associated with later risk of type 1 diabetes: results from two large Danish population-based studies.

Jacobsen R, Thorsen SU, Cohen AS, Lundqvist M, Frederiksen P, Pipper CB, Pociot F, Thygesen LC, Ascherio A, Svensson J, Heitmann BL.

Diabetologia. 2016 Sep;59(9):1871-81. doi: 10.1007/s00125-016-4002-8. Epub 2016 May 30.


Increased mortality in a Danish cohort of young people with Type 1 diabetes mellitus followed for 24 years.

Sandahl K, Nielsen LB, Svensson J, Johannesen J, Pociot F, Mortensen HB, Hougaard P, Broe R, Rasmussen ML, Grauslund J, Peto T, Olsen BS.

Diabet Med. 2017 Mar;34(3):380-386. doi: 10.1111/dme.13124. Epub 2016 Apr 21.


Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.

Ram R, Mehta M, Nguyen QT, Larma I, Boehm BO, Pociot F, Concannon P, Morahan G.

J Immunol. 2016 Apr 1;196(7):3043-53. doi: 10.4049/jimmunol.1502056. Epub 2016 Feb 24.


Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

Brorsson CA, Nielsen LB, Andersen ML, Kaur S, Bergholdt R, Hansen L, Mortensen HB, Pociot F, Størling J; Hvidoere Study Group On Childhood Diabetes.

J Diabetes Res. 2016;2016:9570424. doi: 10.1155/2016/9570424. Epub 2016 Jan 20.


Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line.

Jacobsen KS, Nielsen KO, Winther TN, Glebe D, Pociot F, Hogh B.

BMC Res Notes. 2016 Jan 22;9:38. doi: 10.1186/s13104-016-1848-2.


A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.

Fukaya M, Brorsson CA, Meyerovich K, Catrysse L, Delaroche D, Vanzela EC, Ortis F, Beyaert R, Nielsen LB, Andersen ML, Mortensen HB, Pociot F, van Loo G, Størling J, Cardozo AK.

Mol Endocrinol. 2016 Jan;30(1):48-61. doi: 10.1210/me.2015-1176. Epub 2015 Dec 10.


Lipidomic and metabolomic characterization of a genetically modified mouse model of the early stages of human type 1 diabetes pathogenesis.

Overgaard AJ, Weir JM, De Souza DP, Tull D, Haase C, Meikle PJ, Pociot F.

Metabolomics. 2016;12(1):13. Epub 2015 Nov 17.


Genetic Determinants of Enterovirus Infections: Polymorphisms in Type 1 Diabetes and Innate Immune Genes in the MIDIA Study.

Witsø E, Cinek O, Tapia G, Brorsson CA, Stene LC, Gjessing HK, Rasmussen T, Bergholdt R, Pociot FM, Rønningen KS.

Viral Immunol. 2015 Dec;28(10):556-63. doi: 10.1089/vim.2015.0067. Epub 2015 Oct 20.


The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus.

Kaur S, Mirza AH, Brorsson CA, Fløyel T, Størling J, Mortensen HB, Pociot F; Hvidoere International Study Group.

Mol Cell Endocrinol. 2016 Jan 5;419:83-91. doi: 10.1016/j.mce.2015.10.002. Epub 2015 Oct 9.


MicroRNAs as regulators of beta-cell function and dysfunction.

Osmai M, Osmai Y, Bang-Berthelsen CH, Pallesen EM, Vestergaard AL, Novotny GW, Pociot F, Mandrup-Poulsen T.

Diabetes Metab Res Rev. 2016 May;32(4):334-49. doi: 10.1002/dmrr.2719. Epub 2015 Nov 11. Review.


Shared Genetic Basis for Type 1 Diabetes, Islet Autoantibodies, and Autoantibodies Associated With Other Immune-Mediated Diseases in Families With Type 1 Diabetes.

Brorsson CA, Pociot F; Type 1 Diabetes Genetics Consortium.

Diabetes Care. 2015 Oct;38 Suppl 2:S8-13. doi: 10.2337/dcs15-2003.


Genes affecting β-cell function in type 1 diabetes.

Fløyel T, Kaur S, Pociot F.

Curr Diab Rep. 2015 Nov;15(11):97. doi: 10.1007/s11892-015-0655-9. Review.


Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).

Thorsen SU, Sandahl K, Nielsen LB, Broe R, Rasmussen ML, Peto T, Grauslund J, Andersen ML, Mortensen HB, Pociot F, Olsen BS, Brorsson C.

Graefes Arch Clin Exp Ophthalmol. 2015 Nov;253(11):1959-65. doi: 10.1007/s00417-015-3118-8. Epub 2015 Aug 6.


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