Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 91


Implementation of a High-Throughput Pilot Screen in Peptide Hydrogel-Based Three-Dimensional Cell Cultures.

Worthington P, Drake KM, Li Z, Napper AD, Pochan DJ, Langhans SA.

SLAS Discov. 2019 Apr 30:2472555219844570. doi: 10.1177/2472555219844570. [Epub ahead of print]


Experiments and Simulations of Complex Sugar-Based Coil-Brush Block Polymer Nanoassemblies in Aqueous Solution.

Dong M, Wessels MG, Lee JY, Su L, Wang H, Letteri RA, Song Y, Lin YN, Chen Y, Li R, Pochan DJ, Jayaraman A, Wooley KL.

ACS Nano. 2019 May 28;13(5):5147-5162. doi: 10.1021/acsnano.8b08811. Epub 2019 Apr 16.


Twisted Ribbon Aggregates in a Model Peptide System.

Rüter A, Kuczera S, Pochan DJ, Olsson U.

Langmuir. 2019 Apr 30;35(17):5802-5808. doi: 10.1021/acs.langmuir.8b03886. Epub 2019 Apr 18.


Nanotubes, Plates, and Needles: Pathway-Dependent Self-Assembly of Computationally Designed Peptides.

Tian Y, Polzer FB, Zhang HV, Kiick KL, Saven JG, Pochan DJ.

Biomacromolecules. 2018 Nov 12;19(11):4286-4298. doi: 10.1021/acs.biomac.8b01163. Epub 2018 Oct 9.


Block copolymer crystalsomes with an ultrathin shell to extend blood circulation time.

Qi H, Zhou H, Tang Q, Lee JY, Fan Z, Kim S, Staub MC, Zhou T, Mei S, Han L, Pochan DJ, Cheng H, Hu W, Li CY.

Nat Commun. 2018 Aug 1;9(1):3005. doi: 10.1038/s41467-018-05396-x.


Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles.

Haider MJ, Zhang HV, Sinha N, Fagan JA, Kiick KL, Saven JG, Pochan DJ.

Soft Matter. 2018 Jul 4;14(26):5488-5496. doi: 10.1039/c8sm00435h.


Dynamic protein folding at the surface of stimuli-responsive peptide fibrils.

Nagarkar RP, Miller SE, Zhong S, Pochan DJ, Schneider JP.

Protein Sci. 2018 Jul;27(7):1243-1251. doi: 10.1002/pro.3394. Epub 2018 Mar 14.


Beta-hairpin hydrogels as scaffolds for high-throughput drug discovery in three-dimensional cell culture.

Worthington P, Drake KM, Li Z, Napper AD, Pochan DJ, Langhans SA.

Anal Biochem. 2017 Oct 15;535:25-34. doi: 10.1016/j.ab.2017.07.024. Epub 2017 Jul 27.


Transition from disordered aggregates to ordered lattices: kinetic control of the assembly of a computationally designed peptide.

Tian Y, Zhang HV, Kiick KL, Saven JG, Pochan DJ.

Org Biomol Chem. 2017 Aug 7;15(29):6109-6118. doi: 10.1039/c7ob01197k. Epub 2017 Jun 22.


Computationally designed peptides for self-assembly of nanostructured lattices.

Zhang HV, Polzer F, Haider MJ, Tian Y, Villegas JA, Kiick KL, Pochan DJ, Saven JG.

Sci Adv. 2016 Sep 9;2(9):e1600307. doi: 10.1126/sciadv.1600307. eCollection 2016 Sep.


Sustained release of active chemotherapeutics from injectable-solid β-hairpin peptide hydrogel.

Sun JE, Stewart B, Litan A, Lee SJ, Schneider JP, Langhans SA, Pochan DJ.

Biomater Sci. 2016 May 26;4(5):839-48. doi: 10.1039/c5bm00538h. Epub 2016 Feb 24.


Highly branched and loop-rich gels via formation of metal-organic cages linked by polymers.

Zhukhovitskiy AV, Zhong M, Keeler EG, Michaelis VK, Sun JE, Hore MJ, Pochan DJ, Griffin RG, Willard AP, Johnson JA.

Nat Chem. 2016 Jan;8(1):33-41. doi: 10.1038/nchem.2390. Epub 2015 Nov 16.


Glycodendrimersomes from Sequence-Defined Janus Glycodendrimers Reveal High Activity and Sensor Capacity for the Agglutination by Natural Variants of Human Lectins.

Zhang S, Xiao Q, Sherman SE, Muncan A, Ramos Vicente AD, Wang Z, Hammer DA, Williams D, Chen Y, Pochan DJ, Vértesy S, André S, Klein ML, Gabius HJ, Percec V.

J Am Chem Soc. 2015 Oct 21;137(41):13334-44. doi: 10.1021/jacs.5b08844. Epub 2015 Oct 7.


Beta Hairpin Peptide Hydrogels as an Injectable Solid Vehicle for Neurotrophic Growth Factor Delivery.

Lindsey S, Piatt JH, Worthington P, Sönmez C, Satheye S, Schneider JP, Pochan DJ, Langhans SA.

Biomacromolecules. 2015 Sep 14;16(9):2672-83. doi: 10.1021/acs.biomac.5b00541. Epub 2015 Aug 17.


Peptide Hydrogels - Versatile Matrices for 3D Cell Culture in Cancer Medicine.

Worthington P, Pochan DJ, Langhans SA.

Front Oncol. 2015 Apr 20;5:92. doi: 10.3389/fonc.2015.00092. eCollection 2015. Review.


Poly(anhydride-ester) and poly(N-vinyl-2-pyrrolidone) blends: salicylic acid-releasing blends with hydrogel-like properties that reduce inflammation.

Ouimet MA, Fogaça R, Snyder SS, Sathaye S, Catalani LH, Pochan DJ, Uhrich KE.

Macromol Biosci. 2015 Mar;15(3):342-50. doi: 10.1002/mabi.201400238. Epub 2014 Oct 21.


Rheology of peptide- and protein-based physical hydrogels: are everyday measurements just scratching the surface?

Sathaye S, Mbi A, Sonmez C, Chen Y, Blair DL, Schneider JP, Pochan DJ.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Jan-Feb;7(1):34-68. doi: 10.1002/wnan.1299. Epub 2014 Sep 29. Review.


Engineering complementary hydrophobic interactions to control β-hairpin peptide self-assembly, network branching, and hydrogel properties.

Sathaye S, Zhang H, Sonmez C, Schneider JP, MacDermaid CM, Von Bargen CD, Saven JG, Pochan DJ.

Biomacromolecules. 2014 Nov 10;15(11):3891-900. doi: 10.1021/bm500874t. Epub 2014 Oct 17.


Self-assembly of amphiphilic Janus dendrimers into uniform onion-like dendrimersomes with predictable size and number of bilayers.

Zhang S, Sun HJ, Hughes AD, Moussodia RO, Bertin A, Chen Y, Pochan DJ, Heiney PA, Klein ML, Percec V.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9058-63. doi: 10.1073/pnas.1402858111. Epub 2014 Jun 9.


"Single-single" amphiphilic janus dendrimers self-assemble into uniform dendrimersomes with predictable size.

Zhang S, Sun HJ, Hughes AD, Draghici B, Lejnieks J, Leowanawat P, Bertin A, Otero De Leon L, Kulikov OV, Chen Y, Pochan DJ, Heiney PA, Percec V.

ACS Nano. 2014 Feb 25;8(2):1554-65. doi: 10.1021/nn405790x. Epub 2014 Jan 13.


Hyaluronic acid-based hydrogels containing covalently integrated drug depots: implication for controlling inflammation in mechanically stressed tissues.

Xiao L, Tong Z, Chen Y, Pochan DJ, Sabanayagam CR, Jia X.

Biomacromolecules. 2013 Nov 11;14(11):3808-19. doi: 10.1021/bm4011276. Epub 2013 Oct 23.


Disk-cylinder and disk-sphere nanoparticles via a block copolymer blend solution construction.

Zhu J, Zhang S, Zhang K, Wang X, Mays JW, Wooley KL, Pochan DJ.

Nat Commun. 2013;4:2297. doi: 10.1038/ncomms3297.


Responsive organogels formed by supramolecular self assembly of PEG-block-allyl-functionalized racemic polypeptides into β-sheet-driven polymeric ribbons.

Zou J, Zhang F, Chen Y, Raymond JE, Zhang S, Fan J, Zhu J, Li A, Seetho K, He X, Pochan DJ, Wooley KL.

Soft Matter. 2013 Jul 10;9(25):5951-5958.


Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins.

Percec V, Leowanawat P, Sun HJ, Kulikov O, Nusbaum CD, Tran TM, Bertin A, Wilson DA, Peterca M, Zhang S, Kamat NP, Vargo K, Moock D, Johnston ED, Hammer DA, Pochan DJ, Chen Y, Chabre YM, Shiao TC, Bergeron-Brlek M, André S, Roy R, Gabius HJ, Heiney PA.

J Am Chem Soc. 2013 Jun 19;135(24):9055-77. doi: 10.1021/ja403323y. Epub 2013 Jun 6.


Rapid and versatile construction of diverse and functional nanostructures derived from a polyphosphoester-based biomimetic block copolymer system.

Zhang S, Zou J, Zhang F, Elsabahy M, Felder SE, Zhu J, Pochan DJ, Wooley KL.

J Am Chem Soc. 2012 Nov 7;134(44):18467-74. doi: 10.1021/ja309037m. Epub 2012 Oct 23.


Mechano-Responsive Hydrogels Crosslinked by Block Copolymer Micelles.

Xiao L, Zhu J, Londono DJ, Pochan DJ, Jia X.

Soft Matter. 2012 Oct 28;8(40):10233-10237.


Heat-induced morphological transformation of supramolecular nanostructures by retro-Diels-Alder reaction.

Ikeda M, Ochi R, Kurita YS, Pochan DJ, Hamachi I.

Chemistry. 2012 Oct 8;18(41):13091-6. doi: 10.1002/chem.201201670. Epub 2012 Sep 11.


Materials science. Approaching asymmetry and versatility in polymer assembly.

Pochan DJ.

Science. 2012 Aug 3;337(6094):530-1. doi: 10.1126/science.1225524. No abstract available.


Morphological transformations in a dually thermoresponsive coil-rod-coil bioconjugate.

Krishna OD, Wiss KT, Luo T, Pochan DJ, Theato P, Kiick KL.

Soft Matter. 2012 Apr 14;8(14):3832-3840.


Injectable solid peptide hydrogel as a cell carrier: effects of shear flow on hydrogels and cell payload.

Yan C, Mackay ME, Czymmek K, Nagarkar RP, Schneider JP, Pochan DJ.

Langmuir. 2012 Apr 10;28(14):6076-87. doi: 10.1021/la2041746. Epub 2012 Mar 27.


Controlling assembly of helical polypeptides via PEGylation strategies.

Top A, Zhong S, Yan C, Roberts CJ, Pochan DJ, Kiick KL.

Soft Matter. 2011 Oct 20;20(7):9758-9766.


Enhanced mechanical rigidity of hydrogels formed from enantiomeric peptide assemblies.

Nagy KJ, Giano MC, Jin A, Pochan DJ, Schneider JP.

J Am Chem Soc. 2011 Sep 28;133(38):14975-7. doi: 10.1021/ja206742m. Epub 2011 Sep 7.


Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering.

Altunbas A, Pochan DJ.

Top Curr Chem. 2012;310:135-67. doi: 10.1007/128_2011_206. Review.


Controlled shape transformation of polymersome stomatocytes.

Meeuwissen SA, Kim KT, Chen Y, Pochan DJ, van Hest JC.

Angew Chem Int Ed Engl. 2011 Jul 25;50(31):7070-3. doi: 10.1002/anie.201102167. Epub 2011 Jun 17. No abstract available.


Controlled biodegradation of self-assembling β-hairpin peptide hydrogels by proteolysis with matrix metalloproteinase-13.

Giano MC, Pochan DJ, Schneider JP.

Biomaterials. 2011 Sep;32(27):6471-7. doi: 10.1016/j.biomaterials.2011.05.052. Epub 2011 Jun 16.


Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles.

Altunbas A, Lee SJ, Rajasekaran SA, Schneider JP, Pochan DJ.

Biomaterials. 2011 Sep;32(25):5906-14. doi: 10.1016/j.biomaterials.2011.04.069. Epub 2011 May 23.


Injectable solid hydrogel: mechanism of shear-thinning and immediate recovery of injectable β-hairpin peptide hydrogels.

Yan C, Altunbas A, Yucel T, Nagarkar RP, Schneider JP, Pochan DJ.

Soft Matter. 2010 Oct 21;6(20):5143-5156.


Evaluation of Isoprene Chain Extension from PEO Macromolecular Chain Transfer Agents for the Preparation of Dual, Invertible Block Copolymer Nanoassemblies.

Bartels JW, Cauët SI, Billings PL, Lin LY, Zhu J, Fidge C, Pochan DJ, Wooley KL.

Macromolecules. 2010 Sep 14;43(17):7128-7138.


Assembly Properties of an Alanine-Rich, Lysine-Containing Peptide and the Formation of Peptide/Polymer Hybrid Hydrogels.

Grieshaber SE, Nie T, Yan C, Zhong S, Teller SS, Clifton RJ, Pochan DJ, Kiick KL, Jia X.

Macromol Chem Phys. 2011 Feb 1;212(3):229-239.


Zinc-triggered hydrogelation of a self-assembling β-hairpin peptide.

Micklitsch CM, Knerr PJ, Branco MC, Nagarkar R, Pochan DJ, Schneider JP.

Angew Chem Int Ed Engl. 2011 Feb 11;50(7):1577-9. doi: 10.1002/anie.201006652. Epub 2011 Jan 7. No abstract available.


Hybrid, elastomeric hydrogels crosslinked by multifunctional block copolymer micelles.

Xiao L, Liu C, Zhu J, Pochan DJ, Jia X.

Soft Matter. 2010 Nov 7;6(21):5293-5297.


Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin.

Lin LY, Lee NS, Zhu J, Nyström AM, Pochan DJ, Dorshow RB, Wooley KL.

J Control Release. 2011 May 30;152(1):37-48. doi: 10.1016/j.jconrel.2011.01.009. Epub 2011 Jan 15. Erratum in: J Control Release. 2012 Feb 10;157(3):500.


A giant surfactant of polystyrene-(carboxylic Acid-functionalized polyhedral oligomeric silsesquioxane) amphiphile with highly stretched polystyrene tails in micellar assemblies.

Yu X, Zhong S, Li X, Tu Y, Yang S, Van Horn RM, Ni C, Pochan DJ, Quirk RP, Wesdemiotis C, Zhang WB, Cheng SZ.

J Am Chem Soc. 2010 Dec 1;132(47):16741-4. doi: 10.1021/ja1078305. Epub 2010 Nov 4.


The effect of protein structure on their controlled release from an injectable peptide hydrogel.

Branco MC, Pochan DJ, Wagner NJ, Schneider JP.

Biomaterials. 2010 Dec;31(36):9527-34. doi: 10.1016/j.biomaterials.2010.08.047. Epub 2010 Oct 16.


Structure-property correlations in hybrid polymer-nanoparticle electrospun fibers and plasmonic control over their dichroic behavior.

Sharma N, McKeown SJ, Ma X, Pochan DJ, Cloutier SG.

ACS Nano. 2010 Oct 26;4(10):5551-8. doi: 10.1021/nn100582f.


Polymersome stomatocytes: controlled shape transformation in polymer vesicles.

Kim KT, Zhu J, Meeuwissen SA, Cornelissen JJ, Pochan DJ, Nolte RJ, van Hest JC.

J Am Chem Soc. 2010 Sep 15;132(36):12522-4. doi: 10.1021/ja104154t.


Amphiphilic block co-polyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin.

Wang X, Gurski LA, Zhong S, Xu X, Pochan DJ, Farach-Carson MC, Jia X.

J Biomater Sci Polym Ed. 2011;22(10):1275-98. doi: 10.1163/092050610X504260.


Rheological properties of peptide-based hydrogels for biomedical and other applications.

Yan C, Pochan DJ.

Chem Soc Rev. 2010 Sep;39(9):3528-40. doi: 10.1039/b919449p. Epub 2010 Apr 26. Review.


Modular synthesis of biodegradable diblock copolymers for designing functional polymersomes.

Katz JS, Zhong S, Ricart BG, Pochan DJ, Hammer DA, Burdick JA.

J Am Chem Soc. 2010 Mar 24;132(11):3654-5. doi: 10.1021/ja910606y.

Supplemental Content

Loading ...
Support Center