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Items: 1 to 50 of 58

1.

Evaluation of angularly condensed diquinothiazines as potential anticancer agents.

Jeleń M, Pluta K, Latocha M, Morak-Młodawska B, Suwińska K, Kuśmierz D.

Bioorg Chem. 2019 Jun;87:810-820. doi: 10.1016/j.bioorg.2019.04.005. Epub 2019 Apr 6.

PMID:
30981160
2.

Prolongation of skin graft survival in mice by an azaphenothiazine derivative.

Artym J, Kocięba M, Zaczyńska E, Kochanowska I, Zimecki M, Kałas W, Strządała L, Zioło E, Jeleń M, Morak-Młodawska B, Pluta K.

Immunol Lett. 2019 Apr;208:1-7. doi: 10.1016/j.imlet.2019.02.006. Epub 2019 Feb 27.

PMID:
30825456
3.

Synthesis, Anticancer Activity, and Apoptosis Induction of Novel 3,6-Diazaphenothiazines.

Morak-Młodawska B, Pluta K, Latocha M, Jeleń M, Kuśmierz D.

Molecules. 2019 Jan 12;24(2). pii: E267. doi: 10.3390/molecules24020267.

4.

Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction.

Gasecka A, Nieuwland R, Budnik M, Dignat-George F, Eyileten C, Harrison P, Huczek Z, Kapłon-Cieślicka A, Lacroix R, Opolski G, Pluta K, van der Pol E, Postuła M, Leroyer A, Siljander P, Sturk A, Filipiak KJ.

Platelets. 2018 Dec 26:1-7. doi: 10.1080/09537104.2018.1557616. [Epub ahead of print]

PMID:
30585111
5.

An Anti-Inflammatory Azaphenothiazine Inhibits Interferon β Expression and CXCL10 Production in KERTr Cells.

Strzadala L, Fiedorowicz A, Wysokinska E, Ziolo E, Grudzień M, Jelen M, Pluta K, Morak-Mlodawska B, Zimecki M, Kalas W.

Molecules. 2018 Sep 24;23(10). pii: E2443. doi: 10.3390/molecules23102443.

6.

A Review of Selected Factors of Salivary Gland Tumour Formation and Malignant Transformation.

Sowa P, Goroszkiewicz K, Szydelko J, Chechlinska J, Pluta K, Domka W, Misiolek M, Scierski W.

Biomed Res Int. 2018 Aug 1;2018:2897827. doi: 10.1155/2018/2897827. eCollection 2018. Review.

7.

Synthesis and anticancer activity of multisubstituted purines and xanthines with one or two propynylthio and aminobutynylthio groups.

Kowalska A, Pluta K, Latocha M.

Med Chem Res. 2018;27(5):1384-1395. doi: 10.1007/s00044-018-2155-3. Epub 2018 Mar 6.

8.

Topically applied azaphenothiazines inhibit experimental psoriasis in mice.

Artym J, Kocięba M, Zaczyńska E, Kochanowska I, Zimecki M, Kałas W, Fiedorowicz A, Pawlak A, Strządała L, Jeleń M, Morak-Młodawska B, Pluta K, Kaleta-Kuratewicz K, Madej JP, Kuropka P, Kuryszko J.

Int Immunopharmacol. 2018 Jun;59:276-286. doi: 10.1016/j.intimp.2018.03.028. Epub 2018 Apr 16.

PMID:
29674255
9.

P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets: Preliminary results.

Gasecka A, Nieuwland R, van der Pol E, Hajji N, Ćwiek A, Pluta K, Konwerski M, Filipiak KJ.

Cardiol J. 2018 Apr 19. doi: 10.5603/CJ.a2018.0045. [Epub ahead of print]

10.

Bioactivity tests of calcium phosphates with variant molar ratios of main components.

Pluta K, Sobczak-Kupiec A, Półtorak O, Malina D, Tyliszczak B.

J Biomed Mater Res A. 2018 Jul;106(7):1941-1950. doi: 10.1002/jbm.a.36386. Epub 2018 Apr 10.

PMID:
29521034
11.

Lipophilicity of New Anticancer 1,6- and 3,6-diazaphenothiazines by of Use RP TLC and Different Computational Methods.

Morak-Mlodawska B, Pluta K, Jelen M.

J Chromatogr Sci. 2018 Apr 1;56(4):376-381. doi: 10.1093/chromsci/bmy006.

PMID:
29425266
12.

10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes.

Zhang J, Ming C, Zhang W, Okechukwu PN, Morak-Młodawska B, Pluta K, Jeleń M, Akim AM, Ang KP, Ooi KK.

Drug Des Devel Ther. 2017 Oct 24;11:3045-3063. doi: 10.2147/DDDT.S144415. eCollection 2017.

13.

Liver tissue fragments obtained from males are the most promising source of human hepatocytes for cell-based therapies - Flow cytometric analysis of albumin expression.

Zakrzewska KE, Samluk A, Wencel A, Dudek K, Pijanowska DG, Pluta KD.

PLoS One. 2017 Aug 9;12(8):e0182846. doi: 10.1371/journal.pone.0182846. eCollection 2017.

14.

Topically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice.

Artym J, Kocięba M, Zaczyńska E, Zimecki M, Jeleń M, Morak-Młodawska B, Pluta K, Kaleta-Kuratewicz K, Madej JP, Kuropka P, Kuryszko J.

Histol Histopathol. 2018 Feb;33(2):223-236. doi: 10.14670/HH-11-921. Epub 2017 Jul 27.

PMID:
28748525
15.

Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.

Pluta K, Jeleń M, Morak-Młodawska B, Zimecki M, Artym J, Kocięba M, Zaczyńska E.

Eur J Med Chem. 2017 Sep 29;138:774-806. doi: 10.1016/j.ejmech.2017.07.009. Epub 2017 Jul 8. Review.

PMID:
28734245
16.

Dried human skin fibroblasts as a new substratum for functional culture of hepatic cells.

Wencel A, Zakrzewska KE, Samluk A, Noszczyk BH, Pijanowska DG, Pluta KD.

Acta Biochim Pol. 2017;64(2):357-363. doi: 10.18388/abp.2016_1481. Epub 2017 Jun 9.

17.

Vitamin B12 Catalysis: Probing the Structure/Efficacy Relationship.

Karczewski M, Ociepa M, Pluta K, Ó Proinsias K, Gryko D.

Chemistry. 2017 May 23;23(29):7024-7030. doi: 10.1002/chem.201606059. Epub 2017 Mar 30.

PMID:
28198056
18.

Synthesis, spectroscopic characterization, and anticancer activity of new 10-substituted 1,6-diazaphenothiazines.

Morak-Młodawska B, Pluta K, Latocha M, Jeleń M.

Med Chem Res. 2016;25(11):2425-2433. Epub 2016 Aug 4.

19.

Synthesis and anticancer and lipophilic properties of 10-dialkylaminobutynyl derivatives of 1,8- and 2,7-diazaphenothiazines.

Morak-Młodawska B, Pluta K, Latocha M, Jeleń M, Kuśmierz D.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1132-8. doi: 10.3109/14756366.2015.1101092. Epub 2015 Nov 2.

PMID:
27677322
20.

Selected azaphenothiazines inhibit delayed type hypersensitivity and carrageenan reaction in mice.

Artym J, Kochanowska IE, Kocięba M, Zaczyńska E, Zimecki M, Jeleń M, Morak-Młodawska B, Pluta K.

Int Immunopharmacol. 2016 Nov;40:265-268. doi: 10.1016/j.intimp.2016.09.005. Epub 2016 Sep 12.

PMID:
27632704
21.

Synthesis and biological evaluation of novel propargylquinobenzothiazines and their derivatives as potential antiproliferative, anti-inflammatory, and anticancer agents.

Jeleń M, Pluta K, Zimecki M, Morak-Młodawska B, Artym J, Kocięba M, Kochanowska I.

J Enzyme Inhib Med Chem. 2016;31(sup3):83-88. Epub 2016 Jul 12.

PMID:
27404955
22.

Vitamin B12 Phosphate Conjugation and Its Effect on Binding to the Human B12 -Binding Proteins Intrinsic Factor and Haptocorrin.

Ó Proinsias K, Ociepa M, Pluta K, Chromiński M, Nexo E, Gryko D.

Chemistry. 2016 Jun 6;22(24):8282-9. doi: 10.1002/chem.201504898. Epub 2016 Apr 27.

PMID:
27120016
23.

3,6-Diazaphenothiazines as potential lead molecules - synthesis, characterization and anticancer activity.

Morak-Młodawska B, Pluta K, Latocha M, Suwińska K, Jeleń M, Kuśmierz D.

J Enzyme Inhib Med Chem. 2016 Dec;31(6):1512-9. doi: 10.3109/14756366.2016.1151014. Epub 2016 Mar 7.

PMID:
26950280
24.

Interaction of the serine hydrolase KIAA1363 with organophosphorus agents: Evaluation of potency and kinetics.

Ross MK, Pluta K, Bittles V, Borazjani A, Allen Crow J.

Arch Biochem Biophys. 2016 Jan 15;590:72-81. doi: 10.1016/j.abb.2015.11.034. Epub 2015 Nov 23.

25.

Synthesis and anticancer activity of thiosubstituted purines.

Kowalska A, Latocha M, Pluta K.

Med Chem Res. 2015;24(7):3107-3116. Epub 2015 Mar 25.

26.

Analysis of the cytotoxicity of carbon-based nanoparticles, diamond and graphite, in human glioblastoma and hepatoma cell lines.

Zakrzewska KE, Samluk A, Wierzbicki M, Jaworski S, Kutwin M, Sawosz E, Chwalibog A, Pijanowska DG, Pluta KD.

PLoS One. 2015 Mar 27;10(3):e0122579. doi: 10.1371/journal.pone.0122579. eCollection 2015.

27.

Synthesis of quinoline/naphthalene-containing azaphenothiazines and their potent in vitro antioxidant properties.

Jeleń M, Bavavea EI, Pappa M, Kourounakis AP, Morak-Młodawska B, Pluta K.

Med Chem Res. 2015;24(4):1725-1732. Epub 2014 Sep 12.

28.

Synthesis and selected immunological properties of 10-substituted 1,8-diazaphenothiazines.

Morak-Młodawska B, Pluta K, Zimecki M, Jeleń M, Artym J, Kocięba M.

Med Chem Res. 2015;24(4):1408-1418. Epub 2014 Aug 19.

29.

Fertility and genomics: comparison of gene expression in contrasting reproductive tissues of female cattle.

McGettigan PA, Browne JA, Carrington SD, Crowe MA, Fair T, Forde N, Loftus BJ, Lohan A, Lonergan P, Pluta K, Mamo S, Murphy A, Roche J, Walsh SW, Creevey CJ, Earley B, Keady S, Kenny DA, Matthews D, McCabe M, Morris D, O'Loughlin A, Waters S, Diskin MG, Evans AC.

Reprod Fertil Dev. 2016;28(1-2):11-24. doi: 10.1071/RD15354.

PMID:
27062871
30.

Antimicrobial properties of substituted quino[3,2-b]benzo[1,4]thiazines.

Czarny A, Zaczyńska E, Jeleń M, Zimecki M, Pluta K, Morak-Młodawska B, Artym J, Kocięba M.

Pol J Microbiol. 2014;63(3):335-9.

31.

6-Substituted 9-fluoroquino[3,2-b]benzo[1,4]thiazines display strong antiproliferative and antitumor properties.

Jeleń M, Pluta K, Zimecki M, Morak-Młodawska B, Artym J, Kocięba M.

Eur J Med Chem. 2015 Jan 7;89:411-20. doi: 10.1016/j.ejmech.2014.10.070. Epub 2014 Oct 24.

PMID:
25462256
32.

Evaluation of the effects of antibiotics on cytotoxicity of EGFP and DsRed2 fluorescent proteins used for stable cell labeling.

Zakrzewska KE, Samluk A, Pluta KD, Pijanowska DG.

Acta Biochim Pol. 2014;61(4):809-13. Epub 2014 Nov 7.

33.

Estimation of the lipophilicity of new anticancer and immunosuppressive 1,8-diazaphenothiazine derivatives.

Morak-Młodawska B, Pluta K, Jeleń M.

J Chromatogr Sci. 2015 Apr;53(4):462-6. doi: 10.1093/chromsci/bmu065. Epub 2014 Jun 30.

PMID:
24981982
34.

Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.

Lodarski K, Jończyk J, Guzior N, Bajda M, Gładysz J, Walczyk J, Jeleń M, Morak-Młodawska B, Pluta K, Malawska B.

J Enzyme Inhib Med Chem. 2015 Feb;30(1):98-106. doi: 10.3109/14756366.2014.889127. Epub 2014 Mar 25.

PMID:
24666296
35.

6-[3-(p-Tolyl-sulfonyl-amino)-prop-yl]diquino-thia-zine.

Jeleń M, Shkurenko A, Suwińska K, Pluta K, Morak-Młodawska B.

Acta Crystallogr Sect E Struct Rep Online. 2013 May 25;69(Pt 6):o972-3. doi: 10.1107/S1600536813013950. Print 2013 Jun 1.

36.

Generation of fluorescently labeled cell lines, C3A hepatoma cells, and human adult skin fibroblasts to study coculture models.

Samluk A, Zakrzewska KE, Pluta KD.

Artif Organs. 2013 Jul;37(7):E123-30. doi: 10.1111/aor.12064. Epub 2013 Apr 15.

PMID:
23581829
37.

Synthesis and selected immunological properties of substituted quino[3,2-b]benzo[1,4]thiazines.

Jeleń M, Pluta K, Zimecki M, Morak-Młodawska B, Artym J, Kocięba M.

Eur J Med Chem. 2013 May;63:444-56. doi: 10.1016/j.ejmech.2013.02.023. Epub 2013 Mar 1.

PMID:
23517733
38.

N-[4-(9-Chloro-quino[3,2-b]benzo[1,4]thia-zin-6-yl)but-yl]acetamide.

Jeleń M, Suwińska K, Pluta K, Morak-Młodawska B.

Acta Crystallogr Sect E Struct Rep Online. 2012 Dec 1;68(Pt 12):o3324-5. doi: 10.1107/S1600536812045680. Epub 2012 Nov 10.

39.

Molecular aspects of mucin biosynthesis and mucus formation in the bovine cervix during the periestrous period.

Pluta K, McGettigan PA, Reid CJ, Browne JA, Irwin JA, Tharmalingam T, Corfield A, Baird A, Loftus BJ, Evans AC, Carrington SD.

Physiol Genomics. 2012 Dec 18;44(24):1165-78. doi: 10.1152/physiolgenomics.00088.2012. Epub 2012 Oct 23.

PMID:
23092952
40.

10-(Prop-2-yn-1-yl)-2,7-diaza-phenothia-zine.

Morak-Młodawska B, Suwińska K, Pluta K, Jeleń M.

Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1590-1. doi: 10.1107/S1600536812018879. Epub 2012 May 2.

41.

Glycoproteins and glycosidases of the cervix during the periestrous period in cattle.

Pluta K, Irwin JA, Dolphin C, Richardson L, Fitzpatrick E, Gallagher ME, Reid CJ, Crowe MA, Roche JF, Lonergan P, Carrington SD, Evans AC.

J Anim Sci. 2011 Dec;89(12):4032-42. doi: 10.2527/jas.2011-4187. Epub 2011 Jul 29.

PMID:
21803974
42.

Recent progress in biological activities of synthesized phenothiazines.

Pluta K, Morak-Młodawska B, Jeleń M.

Eur J Med Chem. 2011 Aug;46(8):3179-89. doi: 10.1016/j.ejmech.2011.05.013. Epub 2011 May 12. Review.

PMID:
21620536
43.

Thin-layer chromatographic detection of new azaphenothiazines.

Jeleń M, Morak-Młodawska B, Pluta K.

J Pharm Biomed Anal. 2011 Jun 1;55(3):466-71. doi: 10.1016/j.jpba.2011.02.026. Epub 2011 Feb 26.

PMID:
21429690
44.

Anticancer activity of newly synthesized azaphenothiazines from NCI's anticancer screening bank.

Pluta K, Jeleń M, Morak-Młodawska B, Zimecki M, Artym J, Kocieba M.

Pharmacol Rep. 2010 Mar-Apr;62(2):319-32.

45.

Antioxidant activity of newly synthesized 2,7-diazaphenothiazines.

Morak-Młodawska B, Pluta K, Matralis AN, Kourounakis AP.

Arch Pharm (Weinheim). 2010 May;343(5):268-73. doi: 10.1002/ardp.200900253.

PMID:
20232371
46.

Use of HIV as a gene transfer vector.

Pluta K, Kacprzak MM.

Acta Biochim Pol. 2009;56(4):531-95. Epub 2009 Nov 23. Review.

47.

[New derivatives of phenothiazines with anticancer activities].

Morak-Młodawska B, Jeleń M, Pluta K.

Pol Merkur Lekarski. 2009 Jun;26(156):671-5. Review. Polish.

PMID:
19711740
48.

The immunosuppressive activities of newly synthesized azaphenothiazines in human and mouse models.

Zimecki M, Artym J, Kocieba M, Pluta K, Morak-Młodawska B, Jeleń M.

Cell Mol Biol Lett. 2009;14(4):622-35. doi: 10.2478/s11658-009-0025-1. Epub 2009 Jun 25.

49.

2,6-Dimethoxy-7,9-dimethylpurinium iodide hemihydrate.

Kowalska A, Pluta K, Suwińska K.

Acta Crystallogr C. 2008 Apr;64(Pt 4):o211-3. doi: 10.1107/S0108270108005957. Epub 2008 Mar 8.

PMID:
18391391
50.

Coronary arteries of the roe deer (Capreolus capreolus; Linnaeus 1758) heart.

Frackowiak H, Jasiczak K, Pluta K, Godynicki S.

Pol J Vet Sci. 2007;10(2):105-8.

PMID:
17882934

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