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Items: 43


Site-specific phosphorylation regulates the functions of kindlin-3 in a variety of cells.

Bialkowska K, Sossey-Alaoui K, Pluskota E, Izem L, Qin J, Plow EF.

Life Sci Alliance. 2020 Feb 5;3(3). pii: e201900594. doi: 10.26508/lsa.201900594. Print 2019 Mar.


The Kindlin2-p53-SerpinB2 signaling axis is required for cellular senescence in breast cancer.

Sossey-Alaoui K, Pluskota E, Szpak D, Plow EF.

Cell Death Dis. 2019 Jul 15;10(8):539. doi: 10.1038/s41419-019-1774-z.


VEGFR2 survival and mitotic signaling depends on joint activation of associated C3ar1/C5ar1 and IL-6R-gp130.

Hwang MS, Strainic MG, Pohlmann E, Kim H, Pluskota E, Ramirez-Bergeron DL, Plow EF, Medof ME.

J Cell Sci. 2019 Mar 28;132(6). pii: jcs219352. doi: 10.1242/jcs.219352.


The Kindlin-2 regulation of epithelial-to-mesenchymal transition in breast cancer metastasis is mediated through miR-200b.

Sossey-Alaoui K, Pluskota E, Szpak D, Schiemann WP, Plow EF.

Sci Rep. 2018 May 9;8(1):7360. doi: 10.1038/s41598-018-25373-0.


αMβ2 Is Antiatherogenic in Female but Not Male Mice.

Szpak D, Izem L, Verbovetskiy D, Soloviev DA, Yakubenko VP, Pluskota E.

J Immunol. 2018 Apr 1;200(7):2426-2438. doi: 10.4049/jimmunol.1700313. Epub 2018 Feb 19.


Kindlin-2 interacts with endothelial adherens junctions to support vascular barrier integrity.

Pluskota E, Bledzka KM, Bialkowska K, Szpak D, Soloviev DA, Jones SV, Verbovetskiy D, Plow EF.

J Physiol. 2017 Oct 15;595(20):6443-6462. doi: 10.1113/JP274380. Epub 2017 Sep 21.


Kindlin-2 Regulates the Growth of Breast Cancer Tumors by Activating CSF-1-Mediated Macrophage Infiltration.

Sossey-Alaoui K, Pluskota E, Bialkowska K, Szpak D, Parker Y, Morrison CD, Lindner DJ, Schiemann WP, Plow EF.

Cancer Res. 2017 Sep 15;77(18):5129-5141. doi: 10.1158/0008-5472.CAN-16-2337. Epub 2017 Jul 7.


Integrin-Kindlin3 requirements for microglial motility in vivo are distinct from those for macrophages.

Meller J, Chen Z, Dudiki T, Cull RM, Murtazina R, Bal SK, Pluskota E, Stefl S, Plow EF, Trapp BD, Byzova TV.

JCI Insight. 2017 Jun 2;2(11). pii: 93002. doi: 10.1172/jci.insight.93002. eCollection 2017 Jun 2.


The Upregulation of Integrin αDβ2 (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis.

Aziz MH, Cui K, Das M, Brown KE, Ardell CL, Febbraio M, Pluskota E, Han J, Wu H, Ballantyne CM, Smith JD, Cathcart MK, Yakubenko VP.

J Immunol. 2017 Jun 15;198(12):4855-4867. doi: 10.4049/jimmunol.1602175. Epub 2017 May 12.


Distinct Effects of Integrins αXβ2 and αMβ2 on Leukocyte Subpopulations during Inflammation and Antimicrobial Responses.

Jawhara S, Pluskota E, Cao W, Plow EF, Soloviev DA.

Infect Immun. 2016 Dec 29;85(1). pii: e00644-16. doi: 10.1128/IAI.00644-16. Print 2017 Jan.


Kindlin-2 directly binds actin and regulates integrin outside-in signaling.

Bledzka K, Bialkowska K, Sossey-Alaoui K, Vaynberg J, Pluskota E, Qin J, Plow EF.

J Cell Biol. 2016 Apr 11;213(1):97-108. doi: 10.1083/jcb.201501006. Epub 2016 Apr 4.


Dual role of the leukocyte integrin αMβ2 in angiogenesis.

Soloviev DA, Hazen SL, Szpak D, Bledzka KM, Ballantyne CM, Plow EF, Pluskota E.

J Immunol. 2014 Nov 1;193(9):4712-21. doi: 10.4049/jimmunol.1400202. Epub 2014 Sep 26.


Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.

Xu Z, Chen X, Zhi H, Gao J, Bialkowska K, Byzova TV, Pluskota E, White GC 2nd, Liu J, Plow EF, Ma YQ.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1961-7. doi: 10.1161/ATVBAHA.114.303851. Epub 2014 Jun 26.


Kindlin-3 enhances breast cancer progression and metastasis by activating Twist-mediated angiogenesis.

Sossey-Alaoui K, Pluskota E, Davuluri G, Bialkowska K, Das M, Szpak D, Lindner DJ, Downs-Kelly E, Thompson CL, Plow EF.

FASEB J. 2014 May;28(5):2260-71. doi: 10.1096/fj.13-244004. Epub 2014 Jan 27.


Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism.

Pluskota E, Ma Y, Bledzka KM, Bialkowska K, Soloviev DA, Szpak D, Podrez EA, Fox PL, Hazen SL, Dowling JJ, Ma YQ, Plow EF.

Blood. 2013 Oct 3;122(14):2491-9. doi: 10.1182/blood-2013-04-497669. Epub 2013 Jul 29.


Integrin αXβ₂ is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections.

Jawhara S, Pluskota E, Verbovetskiy D, Skomorovska-Prokvolit O, Plow EF, Soloviev DA.

J Immunol. 2012 Sep 1;189(5):2468-77. doi: 10.4049/jimmunol.1200524. Epub 2012 Jul 27.


Integrin signaling in vascular function.

Malinin NL, Pluskota E, Byzova TV.

Curr Opin Hematol. 2012 May;19(3):206-11. doi: 10.1097/MOH.0b013e3283523df0. Review.


The integrin coactivator kindlin-2 plays a critical role in angiogenesis in mice and zebrafish.

Pluskota E, Dowling JJ, Gordon N, Golden JA, Szpak D, West XZ, Nestor C, Ma YQ, Bialkowska K, Byzova T, Plow EF.

Blood. 2011 May 5;117(18):4978-87. doi: 10.1182/blood-2010-11-321182. Epub 2011 Mar 4.


Plasminogen and its receptors as regulators of cardiovascular inflammatory responses.

Das R, Pluskota E, Plow EF.

Trends Cardiovasc Med. 2010 May;20(4):120-4. doi: 10.1016/j.tcm.2010.10.002. Review.


αMβ₂ integrin activation prevents alternative activation of human and murine macrophages and impedes foam cell formation.

Yakubenko VP, Bhattacharjee A, Pluskota E, Cathcart MK.

Circ Res. 2011 Mar 4;108(5):544-54. doi: 10.1161/CIRCRESAHA.110.231803. Epub 2011 Jan 20.


Thrombospondin-4 regulates vascular inflammation and atherogenesis.

Frolova EG, Pluskota E, Krukovets I, Burke T, Drumm C, Smith JD, Blech L, Febbraio M, Bornstein P, Plow EF, Stenina OI.

Circ Res. 2010 Nov 26;107(11):1313-25. doi: 10.1161/CIRCRESAHA.110.232371. Epub 2010 Sep 30.


Neutrophil apoptosis: selective regulation by different ligands of integrin alphaMbeta2.

Pluskota E, Soloviev DA, Szpak D, Weber C, Plow EF.

J Immunol. 2008 Sep 1;181(5):3609-19.


Expression, activation, and function of integrin alphaMbeta2 (Mac-1) on neutrophil-derived microparticles.

Pluskota E, Woody NM, Szpak D, Ballantyne CM, Soloviev DA, Simon DI, Plow EF.

Blood. 2008 Sep 15;112(6):2327-35. doi: 10.1182/blood-2007-12-127183. Epub 2008 May 28.


Identification of pH-regulated antigen 1 released from Candida albicans as the major ligand for leukocyte integrin alphaMbeta2.

Soloviev DA, Fonzi WA, Sentandreu R, Pluskota E, Forsyth CB, Yadav S, Plow EF.

J Immunol. 2007 Feb 15;178(4):2038-46.


Cell adhesion and migration assays.

Soloviev DA, Pluskota E, Plow EF.

Methods Mol Med. 2006;129:267-78.


Novel alpha1-adrenergic receptor signaling pathways: secreted factors and interactions with the extracellular matrix.

Shi T, Duan ZH, Papay R, Pluskota E, Gaivin RJ, de la Motte CA, Plow EF, Perez DM.

Mol Pharmacol. 2006 Jul;70(1):129-42. Epub 2006 Apr 14.


Mechanism and effect of thrombospondin-4 polymorphisms on neutrophil function.

Pluskota E, Stenina OI, Krukovets I, Szpak D, Topol EJ, Plow EF.

Blood. 2005 Dec 1;106(12):3970-8. Epub 2005 Aug 11.


Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2.

Solovjov DA, Pluskota E, Plow EF.

J Biol Chem. 2005 Jan 14;280(2):1336-45. Epub 2004 Oct 14.


Integrin alphaMbeta2 orchestrates and accelerates plasminogen activation and fibrinolysis by neutrophils.

Pluskota E, Soloviev DA, Bdeir K, Cines DB, Plow EF.

J Biol Chem. 2004 Apr 23;279(17):18063-72. Epub 2004 Feb 9.


Fibrinogen interactions with ICAM-1 (CD54) regulate endothelial cell survival.

Pluskota E, D'Souza SE.

Eur J Biochem. 2000 Aug;267(15):4693-704.


Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification.

Kobylańska A, Pluskota E, Swiatkowska M, Wójcik M, Cierniewska-Cieślak A, Krakowiak A, Boczkowska M, Pawłowska Z, Okruszek A, Koziołkiewicz M, Cierniewski CS, Stec WJ.

Acta Biochim Pol. 1999;46(3):679-91.


The cytotoxicity of anti-PAI-1 oligonucleotides and their conjugates.

Kobylańska A, Pluskota E, Pawłowska Z, Okruszek A, Cierniewski CS, Stec WJ.

Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1709-10.


Synthesis, biochemical and biological studies on oligonucleotides bearing a lipophilic dimethoxytrityl group.

Misiura K, Wójcik M, Krakowiak A, Koziołkiewicz M, Pawłowska Z, Pluskota E, Cierniewski CS, Stec WJ.

Acta Biochim Pol. 1998;45(1):27-32.


Modulation of plasminogen activator inhibitor type-1 biosynthesis in vitro and in vivo with oligo(nucleoside phosphorothioate)s and related constructs.

Buczko W, Cierniewski C, Kobylańska A, Koziołkiewicz M, Okruszek A, Pawłowska Z, Pluskota E, Stec WJ.

Pharmacol Ther. 1997 Oct-Dec;76(1-3):161-75. Review.


Phosphorothioate oligodeoxyribonucleotides antisense to PAI-1 mRNA increase fibrinolysis and modify experimental thrombosis in rats.

Pawlowska Z, Pluskota E, Chabielska E, Buczko W, Okruszek A, Stec WJ, Cierniewski CS.

Thromb Haemost. 1998 Feb;79(2):348-53.


Stereodependent inhibition of plasminogen activator inhibitor type 1 by phosphorothioate oligonucleotides: proof of sequence specificity in cell culture and in vivo rat experiments.

Stec WJ, Cierniewski CS, Okruszek A, Kobylańska A, Pawłowska Z, Koziołkiewicz M, Pluskota E, Maciaszek A, Rebowska B, Stasiak M.

Antisense Nucleic Acid Drug Dev. 1997 Dec;7(6):567-73.


Antigenic properties of fibrinogen component of Hemaseel HMN subjected to the antiviral severe dry heat treatment.

Cierniewski CS, Pluskota E, Cieslak M, Brodniewicz T, Nowotarski M.

Thromb Res. 1996 May 15;82(4):349-59.


Microenvironmental changes in platelet membranes induced by the interaction of fibrinogen-derived peptide ligands with platelet integrins.

Watala C, Gwoźdiński K, Pluskota E, Dzieciatkowska E, Cierniewski CS.

Eur J Biochem. 1996 Jan 15;235(1-2):281-8.


Internalization of oligodeoxynucleotide antisense to type-1 plasminogen activator inhibitor mRNA in endothelial cells: a three-dimensional reconstruction by confocal microscopy.

Wyroba E, Pawlowska Z, Kobylanska A, Pluskota E, Maszewska M, Stec WJ, Cierniewski CS.

Biol Cell. 1996;87(1-2):37-43.


Diabetes mellitus alters the effect of peptide and protein ligands on membrane fluidity of blood platelets.

Watala C, Gwoździński K, Pluskota E, Pietrucha T, Walkowiak B, Trojanowski Z, Cierniewski CS.

Thromb Haemost. 1996 Jan;75(1):147-53.


[Regulation of fibrinogen molecule synthesis].

Pluskota E, Cierniewski CS.

Postepy Biochem. 1995;41(2):115-20. Polish. No abstract available.


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