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Items: 1 to 50 of 256

1.

Using in vitro lipolysis and SPECT/CT in vivo imaging to understand oral absorption of fenofibrate from lipid-based drug delivery systems.

Tran T, Bønløkke P, Rodríguez-Rodríguez C, Nosrati Z, Esquinas PL, Borkar N, Plum J, Strindberg S, Karagiozov S, Rades T, Müllertz A, Saatchi K, Häfeli UO.

J Control Release. 2020 Jan 10;317:375-384. doi: 10.1016/j.jconrel.2019.11.024. Epub 2019 Nov 23.

PMID:
31765705
2.

Comparison of induction methods for supersaturation: pH shift versus solvent shift.

Plum J, Bavnhøj C, Palmelund H, Pérez-Alós L, Müllertz A, Rades T.

Int J Pharm. 2020 Jan 5;573:118862. doi: 10.1016/j.ijpharm.2019.118862. Epub 2019 Nov 20.

PMID:
31759102
3.

Developing a predictive in vitro dissolution model based on gastrointestinal fluid characterisation in rats.

Christfort JF, Strindberg S, Plum J, Hall-Andersen J, Janfelt C, Nielsen LH, Müllertz A.

Eur J Pharm Biopharm. 2019 Sep;142:307-314. doi: 10.1016/j.ejpb.2019.07.007. Epub 2019 Jul 6.

PMID:
31288077
4.

Attitudes and Practices Regarding Responsible Beverage Service: Focus Group Discussions With Bar and Restaurant Management and Staff.

Ecklund AM, Nederhoff DM, Hunt SL, Horvath KJ, Nelson TF, Plum JE, Toomey TL.

J Drug Educ. 2017 Sep-Dec;47(3-4):87-107. doi: 10.1177/0047237918790550. Epub 2018 Aug 19.

5.

Structured reporting of x-rays for atraumatic shoulder pain: advantages over free text?

Schöppe F, Sommer WH, Schmidutz F, Pförringer D, Armbruster M, Paprottka KJ, Plum JLV, Sabel BO, Meinel FG, Sommer NN.

BMC Med Imaging. 2018 Jul 3;18(1):20. doi: 10.1186/s12880-018-0262-8.

6.

Structured Reporting of CT Angiography Runoff Examinations of the Lower Extremities.

Sabel BO, Plum JL, Czihal M, Lottspeich C, Schönleben F, Gäbel G, Schinner R, Schoeppe F, Meinel FG.

Eur J Vasc Endovasc Surg. 2018 May;55(5):679-687. doi: 10.1016/j.ejvs.2018.01.026. Epub 2018 Apr 4.

7.

Characterization of the Hydrodynamics in a Miniaturized Dissolution Apparatus.

Johansson KE, Plum J, Mosleh M, Madsen CM, Rades T, Müllertz A.

J Pharm Sci. 2018 Apr;107(4):1095-1103. doi: 10.1016/j.xphs.2017.11.022. Epub 2017 Dec 9.

PMID:
29233728
8.

Investigation of the Intra- and Interlaboratory Reproducibility of a Small Scale Standardized Supersaturation and Precipitation Method.

Plum J, Madsen CM, Teleki A, Bevernage J, da Costa Mathews C, Karlsson EM, Carlert S, Holm R, Müller T, Matthews W, Sayers A, Ojala K, Tsinsman K, Lingamaneni R, Bergström CA, Rades T, Müllertz A.

Mol Pharm. 2017 Dec 4;14(12):4161-4169. doi: 10.1021/acs.molpharmaceut.7b00419. Epub 2017 Nov 7.

PMID:
29043811
9.

Development of a Video-Microscopic Tool To Evaluate the Precipitation Kinetics of Poorly Water Soluble Drugs: A Case Study with Tadalafil and HPMC.

Christfort JF, Plum J, Madsen CM, Nielsen LH, Sandau M, Andersen K, Müllertz A, Rades T.

Mol Pharm. 2017 Dec 4;14(12):4154-4160. doi: 10.1021/acs.molpharmaceut.7b00422. Epub 2017 Aug 16.

PMID:
28763224
10.

A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties.

Van Acker A, Gronke K, Biswas A, Martens L, Saeys Y, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Plum J, Dunay IR, Diefenbach A, Leclercq G.

Cell Rep. 2017 May 16;19(7):1431-1443. doi: 10.1016/j.celrep.2017.04.068.

11.

Structured reporting of CT examinations in acute pulmonary embolism.

Sabel BO, Plum JL, Kneidinger N, Leuschner G, Koletzko L, Raziorrouh B, Schinner R, Kunz WG, Schoeppe F, Thierfelder KM, Sommer WH, Meinel FG.

J Cardiovasc Comput Tomogr. 2017 May - Jun;11(3):188-195. doi: 10.1016/j.jcct.2017.02.008. Epub 2017 Feb 22.

PMID:
28259629
12.

The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression.

Van Acker A, Louagie E, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Elewaut D, Taghon T, Vandekerckhove B, Plum J, Leclercq G.

Cancer Immunol Immunother. 2016 Nov;65(11):1365-1375. Epub 2016 Sep 1.

PMID:
27585789
13.

Studying the Propensity of Compounds to Supersaturate: A Practical and Broadly Applicable Approach.

Palmelund H, Madsen CM, Plum J, Müllertz A, Rades T.

J Pharm Sci. 2016 Oct;105(10):3021-3029. doi: 10.1016/j.xphs.2016.06.016. Epub 2016 Jul 31.

PMID:
27488902
14.

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours.

Filtjens J, Keirsse J, Van Ammel E, Taveirne S, Van Acker A, Kerre T, Taghon T, Vandekerckhove B, Plum J, Van Ginderachter JA, Leclercq G.

Sci Rep. 2016 Jul 29;6:30564. doi: 10.1038/srep30564.

15.

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate.

Van de Walle I, Dolens AC, Durinck K, De Mulder K, Van Loocke W, Damle S, Waegemans E, De Medts J, Velghe I, De Smedt M, Vandekerckhove B, Kerre T, Plum J, Leclercq G, Rothenberg EV, Van Vlierberghe P, Speleman F, Taghon T.

Nat Commun. 2016 Apr 6;7:11171. doi: 10.1038/ncomms11171.

16.

Effect of endoleaks on changes in aortoiliac volume after endovascular repair for abdominal aortic aneurysm.

Meinel FG, Haack M, Weidenhagen R, Hellbach K, Rottenkolber M, Armbruster M, Jerkku T, Thierfelder KM, Plum JL, Koeppel TA, Rubin GD, Sommer WH.

Clin Hemorheol Microcirc. 2016 Nov 25;64(2):135-147.

PMID:
27002893
17.

Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated Caco-2, LLC-PK1 and rat renal SKPT cells.

Rasmussen RN, Lagunas C, Plum J, Holm R, Nielsen CU.

Eur J Pharm Sci. 2016 Jan 20;82:138-46. doi: 10.1016/j.ejps.2015.11.020. Epub 2015 Nov 26.

PMID:
26631583
18.

Notch3 activation is sufficient but not required for inducing human T-lineage specification.

Waegemans E, Van de Walle I, De Medts J, De Smedt M, Kerre T, Vandekerckhove B, Leclercq G, Wang T, Plum J, Taghon T.

J Immunol. 2014 Dec 15;193(12):5997-6004. doi: 10.4049/jimmunol.1400764. Epub 2014 Nov 7.

19.

Ly49E expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases.

Van Acker A, Filtjens J, Van Welden S, Taveirne S, Van Ammel E, Vanhees M, Devisscher L, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G.

PLoS One. 2014 Oct 13;9(10):e110015. doi: 10.1371/journal.pone.0110015. eCollection 2014. Erratum in: PLoS One. 2015;10(4):e0124464.

20.

The use of supersaturation for the vaginal application of microbicides: a case study with dapivirine.

Grammen C, Plum J, Van Den Brande J, Darville N, Augustyns K, Augustijns P, Brouwers J.

J Pharm Sci. 2014 Nov;103(11):3696-3703. doi: 10.1002/jps.24176. Epub 2014 Sep 17.

PMID:
25231545
21.

The anti-epileptic drug substance vigabatrin inhibits taurine transport in intestinal and renal cell culture models.

Plum J, Nøhr MK, Hansen SH, Holm R, Nielsen CU.

Int J Pharm. 2014 Oct 1;473(1-2):395-7. doi: 10.1016/j.ijpharm.2014.07.023. Epub 2014 Jul 22.

PMID:
25062867
22.

Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development.

Filtjens J, Foquet L, Taveirne S, Van Ammel E, Vanhees M, Van Acker A, Kerre T, Taghon T, Vandekerckhove B, Plum J, Van den Steen PE, Leclercq G.

PLoS One. 2014 Jan 30;9(1):e87463. doi: 10.1371/journal.pone.0087463. eCollection 2014.

23.

In vitro generation of mature, naive antigen-specific CD8(+) T cells with a single T-cell receptor by agonist selection.

Snauwaert S, Verstichel G, Bonte S, Goetgeluk G, Vanhee S, Van Caeneghem Y, De Mulder K, Heirman C, Stauss H, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Thielemans K, Kerre T, Vandekerckhove B.

Leukemia. 2014 Apr;28(4):830-41. doi: 10.1038/leu.2013.285. Epub 2013 Oct 4.

PMID:
24091848
24.

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.

Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T.

J Exp Med. 2013 Apr 8;210(4):683-97. doi: 10.1084/jem.20121798. Epub 2013 Mar 25.

25.

Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function.

Filtjens J, Taveirne S, Van Acker A, Van Ammel E, Vanhees M, Kerre T, Taghon T, Vandekerckhove B, Plum J, Leclercq G.

J Leukoc Biol. 2013 May;93(5):699-711. doi: 10.1189/jlb.0812378. Epub 2013 Mar 8.

PMID:
23475576
26.

Differential Ly49e expression pathways in resting versus TCR-activated intraepithelial γδ T cells.

Van Den Broeck T, Van Ammel E, Delforche M, Taveirne S, Kerre T, Vandekerckhove B, Taghon T, Plum J, Leclercq G.

J Immunol. 2013 Mar 1;190(5):1982-90. doi: 10.4049/jimmunol.1200354. Epub 2013 Jan 21.

27.

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia.

Snauwaert S, Vanhee S, Goetgeluk G, Verstichel G, Van Caeneghem Y, Velghe I, Philippé J, Berneman ZN, Plum J, Taghon T, Leclercq G, Thielemans K, Kerre T, Vandekerckhove B.

Haematologica. 2012 Oct;97(10):1539-47. doi: 10.3324/haematol.2012.065581. Epub 2012 Apr 24.

28.

Presence of CXCR4-using HIV-1 in patients with recently diagnosed infection: correlates and evidence for transmission.

Chalmet K, Dauwe K, Foquet L, Baatz F, Seguin-Devaux C, Van Der Gucht B, Vogelaers D, Vandekerckhove L, Plum J, Verhofstede C.

J Infect Dis. 2012 Jan 15;205(2):174-84. doi: 10.1093/infdis/jir714. Epub 2011 Dec 5.

PMID:
22147802
29.

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway.

Van Coppernolle S, Vanhee S, Verstichel G, Snauwaert S, van der Spek A, Velghe I, Sinnesael M, Heemskerk MH, Taghon T, Leclercq G, Plum J, Langerak AW, Kerre T, Vandekerckhove B.

Leukemia. 2012 Jan;26(1):127-38. doi: 10.1038/leu.2011.324. Epub 2011 Nov 4.

PMID:
22051534
30.

Association of haptoglobin phenotypes with the development of Kaposi's sarcoma in HIV patients.

Speeckaert R, Colebunders B, Boelaert JR, Brochez L, Van Acker J, Van Wanzeele F, Hemmer R, Speeckaert MM, Verhofstede C, De Buyzere M, Arendt V, Plum J, Delanghe JR.

Arch Dermatol Res. 2011 Dec;303(10):763-9. doi: 10.1007/s00403-011-1161-9. Epub 2011 Jul 12.

PMID:
21748360
31.

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes.

Taveirne S, Filtjens J, Van Ammel E, De Colvenaer V, Kerre T, Taghon T, Vandekerckhove B, Plum J, Held W, Leclercq G.

Blood. 2011 Jul 14;118(2):339-47. doi: 10.1182/blood-2011-01-331124. Epub 2011 May 25.

PMID:
21613250
32.

Langerhans cells are not required for epidermal Vgamma3 T cell homeostasis and function.

Taveirne S, De Colvenaer V, Van Den Broeck T, Van Ammel E, Bennett CL, Taghon T, Vandekerckhove B, Plum J, Clausen BE, Kaplan DH, Leclercq G.

J Leukoc Biol. 2011 Jul;90(1):61-8. doi: 10.1189/jlb.1010581. Epub 2011 Apr 12.

33.

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T.

Blood. 2011 Apr 28;117(17):4449-59. doi: 10.1182/blood-2010-06-290049. Epub 2011 Mar 3.

34.

T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells.

De Smedt M, Leclercq G, Vandekerckhove B, Kerre T, Taghon T, Plum J.

Haematologica. 2011 May;96(5):646-54. doi: 10.3324/haematol.2010.036343. Epub 2011 Feb 17.

35.

CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation.

De Colvenaer V, Taveirne S, Delforche M, De Smedt M, Vandekerckhove B, Taghon T, Boon L, Plum J, Leclercq G.

Immunol Cell Biol. 2011 Oct;89(7):803-11. doi: 10.1038/icb.2010.171. Epub 2011 Feb 1.

PMID:
21283110
36.

Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.

Vandekerckhove L, Verhofstede C, Demecheleer E, De Wit S, Florence E, Fransen K, Moutschen M, Mostmans W, Kabeya K, Mackie N, Plum J, Vaira D, Van Baelen K, Vandenbroucke I, Van Eygen V, Van Marck H, Vogelaers D, Geretti AM, Stuyver LJ.

J Antimicrob Chemother. 2011 Feb;66(2):265-72. doi: 10.1093/jac/dkq458. Epub 2010 Dec 31.

37.

In vitro generation of immune cells from pluripotent stem cells.

Vandekerckhove B, Vanhee S, Van Coppernolle S, Snauwaert S, Velghe I, Taghon T, Leclercq G, Kerre T, Plum J.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1488-504. Review.

PMID:
21196243
38.

Epidemiological study of phylogenetic transmission clusters in a local HIV-1 epidemic reveals distinct differences between subtype B and non-B infections.

Chalmet K, Staelens D, Blot S, Dinakis S, Pelgrom J, Plum J, Vogelaers D, Vandekerckhove L, Verhofstede C.

BMC Infect Dis. 2010 Sep 7;10:262. doi: 10.1186/1471-2334-10-262.

39.

Rho GTPase Cdc42 is essential for human T-cell development.

Smits K, Iannucci V, Stove V, Van Hauwe P, Naessens E, Meuwissen PJ, Ariën KK, Bentahir M, Plum J, Verhasselt B.

Haematologica. 2010 Mar;95(3):367-75. doi: 10.3324/haematol.2009.006890.

40.

Continuous CD27 triggering in vivo strongly reduces NK cell numbers.

De Colvenaer V, Taveirne S, Hamann J, de Bruin AM, De Smedt M, Taghon T, Vandekerckhove B, Plum J, van Lier R, Leclercq G.

Eur J Immunol. 2010 Apr;40(4):1107-17. doi: 10.1002/eji.200939251.

41.

Viral load assay sensitivity and low level viremia in HAART treated HIV patients.

Verhofstede C, Van Wanzeele F, Reynaerts J, Mangelschots M, Plum J, Fransen K.

J Clin Virol. 2010 Apr;47(4):335-9. doi: 10.1016/j.jcv.2010.01.008. Epub 2010 Feb 6.

PMID:
20138803
42.

A Notch stairway to thymus?

Plum J.

Blood. 2010 Jan 14;115(2):155-6. doi: 10.1182/blood-2009-11-250662. No abstract available.

PMID:
20075167
43.

Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells.

Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M, Leclercq G, Plum J, Taghon T, Vandekerckhove B, Kerre T.

J Immunol. 2009 Oct 15;183(8):4859-70. doi: 10.4049/jimmunol.0900714.

44.

Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya.

Steegen K, Luchters S, Dauwe K, Reynaerts J, Mandaliya K, Jaoko W, Plum J, Temmerman M, Verhofstede C.

AIDS Res Ther. 2009 Jun 16;6:12. doi: 10.1186/1742-6405-6-12.

45.

Generation of T cells from human embryonic stem cell-derived hematopoietic zones.

Timmermans F, Velghe I, Vanwalleghem L, De Smedt M, Van Coppernolle S, Taghon T, Moore HD, Leclercq G, Langerak AW, Kerre T, Plum J, Vandekerckhove B.

J Immunol. 2009 Jun 1;182(11):6879-88. doi: 10.4049/jimmunol.0803670.

46.

CXCR4-using HIV type 1 variants are more commonly found in peripheral blood mononuclear cell DNA than in plasma RNA.

Verhofstede C, Vandekerckhove L, Eygen VV, Demecheleer E, Vandenbroucke I, Winters B, Plum J, Vogelaers D, Stuyver L.

J Acquir Immune Defic Syndr. 2009 Feb 1;50(2):126-36. doi: 10.1097/QAI.0b013e31819118fa.

PMID:
19131897
47.

Endothelial progenitor cells: identity defined?

Timmermans F, Plum J, Yöder MC, Ingram DA, Vandekerckhove B, Case J.

J Cell Mol Med. 2009 Jan;13(1):87-102. doi: 10.1111/j.1582-4934.2008.00598.x. Review.

48.

An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells.

Van de Walle I, De Smet G, De Smedt M, Vandekerckhove B, Leclercq G, Plum J, Taghon T.

Blood. 2009 Mar 26;113(13):2988-98. doi: 10.1182/blood-2008-06-164871. Epub 2008 Dec 3.

PMID:
19056690
49.

Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development.

Taghon T, Van de Walle I, De Smet G, De Smedt M, Leclercq G, Vandekerckhove B, Plum J.

Blood. 2009 Apr 2;113(14):3254-63. doi: 10.1182/blood-2008-07-168906. Epub 2008 Oct 23.

PMID:
18948571
50.

Human intrathymic development: a selective approach.

Plum J, De Smedt M, Leclercq G, Taghon T, Kerre T, Vandekerckhove B.

Semin Immunopathol. 2008 Dec;30(4):411-23. doi: 10.1007/s00281-008-0135-2. Epub 2008 Oct 17. Review.

PMID:
18925396

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