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Items: 13

1.

The cerebral cavernous malformation proteins CCM2L and CCM2 prevent the activation of the MAP kinase MEKK3.

Cullere X, Plovie E, Bennett PM, MacRae CA, Mayadas TN.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14284-9. doi: 10.1073/pnas.1510495112. Epub 2015 Nov 4.

2.

In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector.

Zinn E, Pacouret S, Khaychuk V, Turunen HT, Carvalho LS, Andres-Mateos E, Shah S, Shelke R, Maurer AC, Plovie E, Xiao R, Vandenberghe LH.

Cell Rep. 2015 Aug 11;12(6):1056-68. doi: 10.1016/j.celrep.2015.07.019. Epub 2015 Jul 30.

3.

Arrhythmogenic right ventricular cardiomyopathy mutations alter shear response without changes in cell-cell adhesion.

Hariharan V, Asimaki A, Michaelson JE, Plovie E, MacRae CA, Saffitz JE, Huang H.

Cardiovasc Res. 2014 Nov 1;104(2):280-9. doi: 10.1093/cvr/cvu212. Epub 2014 Sep 24.

4.

Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy.

Asimaki A, Kapoor S, Plovie E, Karin Arndt A, Adams E, Liu Z, James CA, Judge DP, Calkins H, Churko J, Wu JC, MacRae CA, Kléber AG, Saffitz JE.

Sci Transl Med. 2014 Jun 11;6(240):240ra74. doi: 10.1126/scitranslmed.3008008. Erratum in: Sci Transl Med. 2014 Nov 5;6(261):261er6.

5.

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish.

Musso G, Tasan M, Mosimann C, Beaver JE, Plovie E, Carr LA, Chua HN, Dunham J, Zuberi K, Rodriguez H, Morris Q, Zon L, Roth FP, MacRae CA.

Development. 2014 Jan;141(1):224-35. doi: 10.1242/dev.099796.

6.

MicroRNA-26a regulates pathological and physiological angiogenesis by targeting BMP/SMAD1 signaling.

Icli B, Wara AK, Moslehi J, Sun X, Plovie E, Cahill M, Marchini JF, Schissler A, Padera RF, Shi J, Cheng HW, Raghuram S, Arany Z, Liao R, Croce K, MacRae C, Feinberg MW.

Circ Res. 2013 Nov 8;113(11):1231-41. doi: 10.1161/CIRCRESAHA.113.301780. Epub 2013 Sep 18.

7.

Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity.

Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, Falk RH, Semigran MJ, Dec GW Jr, Macrae CA, Liao R.

Basic Res Cardiol. 2013 Sep;108(5):378. doi: 10.1007/s00395-013-0378-5. Epub 2013 Aug 28.

8.

Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.

Arndt AK, Schafer S, Drenckhahn JD, Sabeh MK, Plovie ER, Caliebe A, Klopocki E, Musso G, Werdich AA, Kalwa H, Heinig M, Padera RF, Wassilew K, Bluhm J, Harnack C, Martitz J, Barton PJ, Greutmann M, Berger F, Hubner N, Siebert R, Kramer HH, Cook SA, MacRae CA, Klaassen S.

Am J Hum Genet. 2013 Jul 11;93(1):67-77. doi: 10.1016/j.ajhg.2013.05.015. Epub 2013 Jun 13.

9.

Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish.

Mishra S, Guan J, Plovie E, Seldin DC, Connors LH, Merlini G, Falk RH, MacRae CA, Liao R.

Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H95-103. doi: 10.1152/ajpheart.00186.2013. Epub 2013 Apr 26.

10.

C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling.

Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, MacRae CA, Rosenzweig A, Spiegelman BM.

Cell. 2010 Dec 23;143(7):1072-83. doi: 10.1016/j.cell.2010.11.036.

11.

Expression of the Arabidopsis jasmonate signalling repressor JAZ1/TIFY10A is stimulated by auxin.

Grunewald W, Vanholme B, Pauwels L, Plovie E, Inzé D, Gheysen G, Goossens A.

EMBO Rep. 2009 Aug;10(8):923-8. doi: 10.1038/embor.2009.103. Epub 2009 Jul 3.

12.

AtCDKA;1 silencing in Arabidopsis thaliana reduces reproduction of sedentary plant-parasitic nematodes.

Van de Cappelle E, Plovie E, Kyndt T, Grunewald W, Cannoot B, Gheysen G.

Plant Biotechnol J. 2008 Oct;6(8):749-57. doi: 10.1111/j.1467-7652.2008.00355.x. Epub 2008 Jun 11.

13.

Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy.

Heuser A, Plovie ER, Ellinor PT, Grossmann KS, Shin JT, Wichter T, Basson CT, Lerman BB, Sasse-Klaassen S, Thierfelder L, MacRae CA, Gerull B.

Am J Hum Genet. 2006 Dec;79(6):1081-8. Epub 2006 Oct 3.

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