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Items: 1 to 50 of 251

1.

Preparation of Specific Compartments of the Lungs for Pathologic and Biochemical Analysis of Toxicologic Responses.

Van Winkle LS, Kelty JS, Plopper CG.

Curr Protoc Toxicol. 2017 Feb 1;71:24.5.1-24.5.26. doi: 10.1002/cptx.18.

PMID:
28146282
2.

Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells.

Gharib SA, Altemeier WA, Van Winkle LS, Plopper CG, Schlesinger SY, Buell CA, Brauer R, Lee V, Parks WC, Chen P.

Am J Respir Cell Mol Biol. 2013 Mar;48(3):390-6. doi: 10.1165/rcmb.2012-0083OC. Epub 2012 Dec 20.

3.

Ozone exposure during the early postnatal period alters the timing and pattern of alveolar growth and development in nonhuman primates.

Avdalovic MV, Tyler NK, Putney L, Nishio SJ, Quesenberry S, Singh PJ, Miller LA, Schelegle ES, Plopper CG, Vu T, Hyde DM.

Anat Rec (Hoboken). 2012 Oct;295(10):1707-16. doi: 10.1002/ar.22545. Epub 2012 Aug 13.

4.

Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma.

Plopper CG, Joad JP, Miller LA, Schelegle ES, Fanucchi MV, Van Winkle LS, Tyler NK, Avdalovic MV, Evans MJ, Lasley WL, Buckpitt AR, Pinkerton KE, Tarkington BK, Davis S, Nishio SJ, Gershwin LJ, Wu R, Hyde DM.

Clin Exp Allergy. 2012 Jul;42(7):1104-18. doi: 10.1111/j.1365-2222.2012.04005.x.

5.

Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys.

Carey SA, Plopper CG, Hyde DM, Islam Z, Pestka JJ, Harkema JR.

Toxicol Pathol. 2012 Aug;40(6):887-98. doi: 10.1177/0192623312444028. Epub 2012 May 2.

PMID:
22552393
6.

Persistent rhinitis and epithelial remodeling induced by cyclic ozone exposure in the nasal airways of infant monkeys.

Carey SA, Ballinger CA, Plopper CG, McDonald RJ, Bartolucci AA, Postlethwait EM, Harkema JR.

Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L242-54. doi: 10.1152/ajplung.00177.2010. Epub 2010 Dec 3.

7.

Small particles disrupt postnatal airway development.

Lee D, Wallis C, Wexler AS, Schelegle ES, Van Winkle LS, Plopper CG, Fanucchi MV, Kumfer B, Kennedy IM, Chan JK.

J Appl Physiol (1985). 2010 Oct;109(4):1115-24. doi: 10.1152/japplphysiol.00295.2010. Epub 2010 Jul 15.

8.

Postnatal development of the lamina reticularis in primate airways.

Evans MJ, Fanucchi MV, Plopper CG, Hyde DM.

Anat Rec (Hoboken). 2010 Jun;293(6):947-54. doi: 10.1002/ar.20824. Review.

9.

Airway mast cells in a rhesus model of childhood allergic airways disease.

Van Winkle LS, Baker GL, Chan JK, Schelegle ES, Plopper CG.

Toxicol Sci. 2010 Jul;116(1):313-22. doi: 10.1093/toxsci/kfq119. Epub 2010 Apr 19.

10.

Chronic lung disease in preterm lambs: effect of daily vitamin A treatment on alveolarization.

Albertine KH, Dahl MJ, Gonzales LW, Wang ZM, Metcalfe D, Hyde DM, Plopper CG, Starcher BC, Carlton DP, Bland RD.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L59-72. doi: 10.1152/ajplung.00380.2009. Epub 2010 Apr 9.

11.

Airway trefoil factor expression during naphthalene injury and repair.

Greeley MA, Van Winkle LS, Edwards PC, Plopper CG.

Toxicol Sci. 2010 Feb;113(2):453-67. doi: 10.1093/toxsci/kfp268. Epub 2009 Oct 30.

12.

Postnatal lung development of rhesus monkey airways: cellular expression of Clara cell secretory protein.

Coppens JT, Plopper CG, Murphy SR, Van Winkle LS.

Dev Dyn. 2009 Dec;238(12):3016-24. doi: 10.1002/dvdy.22132.

13.

Ozone and allergen exposure during postnatal development alters the frequency and airway distribution of CD25+ cells in infant rhesus monkeys.

Miller LA, Gerriets JE, Tyler NK, Abel K, Schelegle ES, Plopper CG, Hyde DM.

Toxicol Appl Pharmacol. 2009 Apr 1;236(1):39-48. doi: 10.1016/j.taap.2008.12.031. Epub 2009 Feb 7.

14.

Pulmonary architecture in the conducting regions of six rats.

Lee D, Fanucchi MV, Plopper CG, Fung J, Wexler AS.

Anat Rec (Hoboken). 2008 Aug;291(8):916-26. doi: 10.1002/ar.20726.

15.

Expiration rate drives human airway design.

Lee D, Wexler AS, Fanucchi MV, Plopper CG.

J Theor Biol. 2008 Jul 21;253(2):381-7. doi: 10.1016/j.jtbi.2008.03.013. Epub 2008 Mar 14.

PMID:
18430440
16.

The non-human primate as a model for studying COPD and asthma.

Plopper CG, Hyde DM.

Pulm Pharmacol Ther. 2008 Oct;21(5):755-66. doi: 10.1016/j.pupt.2008.01.008. Epub 2008 Feb 1. Review.

PMID:
18339566
17.

Bifurcation model for characterization of pulmonary architecture.

Lee D, Park SS, Ban-Weiss GA, Fanucchi MV, Plopper CG, Wexler AS.

Anat Rec (Hoboken). 2008 Apr;291(4):379-89. doi: 10.1002/ar.20643.

18.

Assessing the health effects and risks associated with children's inhalation exposures--asthma and allergy.

Selgrade MK, Plopper CG, Gilmour MI, Conolly RB, Foos BS.

J Toxicol Environ Health A. 2008;71(3):196-207. Review.

PMID:
18097945
19.

The effects of inhaled corticosteroids on intrinsic responsiveness and histology of airways from infant monkeys exposed to house dust mite allergen and ozone.

Joad JP, Kott KS, Bric JM, Schelegle ES, Gershwin LJ, Plopper CG, Peake JL, Pinkerton KE.

Toxicol Appl Pharmacol. 2008 Jan 15;226(2):153-60. Epub 2007 Sep 16.

PMID:
17991502
20.

Long-term ozone exposure attenuates 1-nitronaphthalene-induced cytotoxicity in nasal mucosa.

Lee MG, Wheelock AM, Boland B, Plopper CG.

Am J Respir Cell Mol Biol. 2008 Mar;38(3):300-9. Epub 2007 Sep 27.

21.

Asthma/allergic airways disease: does postnatal exposure to environmental toxicants promote airway pathobiology?

Plopper CG, Smiley-Jewell SM, Miller LA, Fanucchi MV, Evans MJ, Buckpitt AR, Avdalovic M, Gershwin LJ, Joad JP, Kajekar R, Larson S, Pinkerton KE, Van Winkle LS, Schelegle ES, Pieczarka EM, Wu R, Hyde DM.

Toxicol Pathol. 2007 Jan;35(1):97-110.

PMID:
17325978
22.

Morphometry of the respiratory tract: avoiding the sampling, size, orientation, and reference traps.

Hyde DM, Tyler NK, Plopper CG.

Toxicol Pathol. 2007 Jan;35(1):41-8.

PMID:
17325971
23.

Three-dimensional mapping of ozone-induced injury in the nasal airways of monkeys using magnetic resonance imaging and morphometric techniques.

Carey SA, Minard KR, Trease LL, Wagner JG, Garcia GJ, Ballinger CA, Kimbell JS, Plopper CG, Corley RA, Postlethwait EM, Harkema JR, Einstein DR.

Toxicol Pathol. 2007 Jan;35(1):27-40. Erratum in: Toxicol Pathol. 2007;35(4):620. Einstein, Daniel R [added].

PMID:
17325970
24.

Distribution of Clara cell secretory protein expression in the tracheobronchial airways of rhesus monkeys.

Coppens JT, Van Winkle LS, Pinkerton K, Plopper CG.

Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1155-62. Epub 2007 Jan 19.

25.

Vascular remodeling is airway generation-specific in a primate model of chronic asthma.

Avdalovic MV, Putney LF, Schelegle ES, Miller L, Usachenko JL, Tyler NK, Plopper CG, Gershwin LJ, Hyde DM.

Am J Respir Crit Care Med. 2006 Nov 15;174(10):1069-76. Epub 2006 Aug 24.

26.

An aerosolized fluorescent microsphere technique for evaluating particle deposition in the avian respiratory tract.

Tell LA, Smiley-Jewell S, Hinds D, Stephens KE, Teague SV, Plopper CG, Pinkerton KE.

Avian Dis. 2006 Jun;50(2):238-44.

PMID:
16863074
27.

Design-based sampling and quantitation of the respiratory airways.

Hyde DM, Harkema JR, Tyler NK, Plopper CG.

Toxicol Pathol. 2006;34(3):286-95.

PMID:
16698728
28.

Cyclic exposure to ozone alters distal airway development in infant rhesus monkeys.

Fanucchi MV, Plopper CG, Evans MJ, Hyde DM, Van Winkle LS, Gershwin LJ, Schelegle ES.

Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L644-50. Epub 2006 Apr 28.

29.

Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium.

Kajekar R, Pieczarka EM, Smiley-Jewell SM, Schelegle ES, Fanucchi MV, Plopper CG.

Respir Physiol Neurobiol. 2007 Jan 15;155(1):55-63. Epub 2006 Apr 17.

PMID:
16616710
30.

Structural and functional localization of airway effects from episodic exposure of infant monkeys to allergen and/or ozone.

Joad JP, Kott KS, Bric JM, Peake JL, Plopper CG, Schelegle ES, Gershwin LJ, Pinkerton KE.

Toxicol Appl Pharmacol. 2006 Aug 1;214(3):237-43. Epub 2006 Feb 7.

PMID:
16466656
31.

Age-specific pulmonary cytochrome P-450 3A1 expression in postnatal and adult rats.

Day KC, Plopper CG, Fanucchi MV.

Am J Physiol Lung Cell Mol Physiol. 2006 Jul;291(1):L75-83. Epub 2006 Feb 3.

32.

Identification of proteins adducted by reactive metabolites of naphthalene and 1-nitronaphthalene in dissected airways of rhesus macaques.

Lin CY, Boland BC, Lee YJ, Salemi MR, Morin D, Miller LA, Plopper CG, Buckpitt AR.

Proteomics. 2006 Feb;6(3):972-82.

PMID:
16453347
33.

Elevation of susceptibility to ozone-induced acute tracheobronchial injury in transgenic mice deficient in Clara cell secretory protein.

Plopper CG, Mango GW, Hatch GE, Wong VJ, Toskala E, Reynolds SD, Tarkington BK, Stripp BR.

Toxicol Appl Pharmacol. 2006 May 15;213(1):74-85. Epub 2005 Oct 14.

PMID:
16226776
34.

Airway generation-specific differences in the spatial distribution of immune cells and cytokines in allergen-challenged rhesus monkeys.

Miller LA, Hurst SD, Coffman RL, Tyler NK, Stovall MY, Chou DL, Putney LF, Gershwin LJ, Schelegle ES, Plopper CG, Hyde DM.

Clin Exp Allergy. 2005 Jul;35(7):894-906.

35.

Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery.

Tarantal AF, McDonald RJ, Jimenez DF, Lee CC, O'Shea CE, Leapley AC, Won RH, Plopper CG, Lutzko C, Kohn DB.

Mol Ther. 2005 Jul;12(1):87-98.

36.

Characterization of a structurally intact in situ lung model and comparison of naphthalene protein adducts generated in this model vs lung microsomes.

Lin CY, Isbell MA, Morin D, Boland BC, Salemi MR, Jewell WT, Weir AJ, Fanucchi MV, Baker GL, Plopper CG, Buckpitt AR.

Chem Res Toxicol. 2005 May;18(5):802-13.

PMID:
15892573
37.

Temporal and spatial distribution of ciliogenesis in the tracheobronchial airways of mice.

Toskala E, Smiley-Jewell SM, Wong VJ, King D, Plopper CG.

Am J Physiol Lung Cell Mol Physiol. 2005 Sep;289(3):L454-9. Epub 2005 May 6.

38.

In vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene in rat lung.

Wheelock AM, Boland BC, Isbell M, Morin D, Wegesser TC, Plopper CG, Buckpitt AR.

Am J Respir Cell Mol Biol. 2005 Aug;33(2):130-7. Epub 2005 Apr 21.

39.

Consequences of abrupt glutathione depletion in murine Clara cells: ultrastructural and biochemical investigations into the role of glutathione loss in naphthalene cytotoxicity.

Phimister AJ, Williams KJ, Van Winkle LS, Plopper CG.

J Pharmacol Exp Ther. 2005 Aug;314(2):506-13. Epub 2005 Apr 21.

PMID:
15845860
40.

Chronic aeroallergen during infancy enhances eotaxin-3 expression in airway epithelium and nerves.

Chou DL, Daugherty BL, McKenna EK, Hsu WM, Tyler NK, Plopper CG, Hyde DM, Schelegle ES, Gershwin LJ, Miller LA.

Am J Respir Cell Mol Biol. 2005 Jul;33(1):1-8. Epub 2005 Apr 15.

41.
42.

Chemokine networks and in vivo T-lymphocyte trafficking in nonhuman primates.

Clay CC, Rodrigues DS, Brignolo LL, Spinner A, Tarara RP, Plopper CG, Leutenegger CM, Esser U.

J Immunol Methods. 2004 Oct;293(1-2):23-42.

PMID:
15541274
43.

Increased vulnerability of neonatal rats and mice to 1-nitronaphthalene-induced pulmonary injury.

Fanucchi MV, Day KC, Clay CC, Plopper CG.

Toxicol Appl Pharmacol. 2004 Nov 15;201(1):53-65.

PMID:
15519608
44.

Smooth muscle hypertrophy in distal airways of sensitized infant rhesus monkeys exposed to house dust mite allergen.

Tran MU, Weir AJ, Fanucchi MV, Rodriguez AE, Pantle LM, Smiley-Jewell SM, Van Winkle LS, Evans MJ, Miller LA, Schelegle ES, Gershwin LJ, Hyde DM, Plopper CG.

Clin Exp Allergy. 2004 Oct;34(10):1627-33.

PMID:
15479280
45.

Impaired recovery from naphthalene-induced bronchiolar epithelial injury in mice exposed to aged and diluted sidestream cigarette smoke.

Van Winkle LS, Brown CD, Shimizu JA, Gunderson AD, Evans MJ, Plopper CG.

Toxicol Lett. 2004 Dec 1;154(1-2):1-9.

PMID:
15475173
46.

Smooth muscle development during postnatal growth of distal bronchioles in infant rhesus monkeys.

Tran MU, Weir AJ, Fanucchi MV, Murphy AE, Van Winkle LS, Evans MJ, Smiley-Jewell SM, Miller L, Schelegle ES, Gershwin LJ, Hyde DM, Plopper CG.

J Appl Physiol (1985). 2004 Dec;97(6):2364-71; discussion 2354. Epub 2004 Sep 3.

47.

Glutathione depletion is a major determinant of inhaled naphthalene respiratory toxicity and naphthalene metabolism in mice.

Phimister AJ, Lee MG, Morin D, Buckpitt AR, Plopper CG.

Toxicol Sci. 2004 Nov;82(1):268-78. Epub 2004 Aug 19.

PMID:
15319489
48.

Immunostimulatory oligonucleotides attenuate airways remodeling in allergic monkeys.

Fanucchi MV, Schelegle ES, Baker GL, Evans MJ, McDonald RJ, Gershwin LJ, Raz E, Hyde DM, Plopper CG, Miller LA.

Am J Respir Crit Care Med. 2004 Dec 1;170(11):1153-7. Epub 2004 Aug 11.

49.

Epithelial cell distribution and abundance in rhesus monkey airways during postnatal lung growth and development.

Van Winkle LS, Fanucchi MV, Miller LA, Baker GL, Gershwin LJ, Schelegle ES, Hyde DM, Evans MJ, Plopper CG.

J Appl Physiol (1985). 2004 Dec;97(6):2355-63; discussion 2354. Epub 2004 Aug 6.

50.

The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery.

Evans MJ, Fanucchi MV, Baker GL, Van Winkle LS, Pantle LM, Nishio SJ, Schelegle ES, Gershwin LJ, Miller LA, Hyde DM, Plopper CG.

Clin Exp Allergy. 2004 Jul;34(7):1131-6.

PMID:
15248862

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