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Items: 1 to 50 of 141

1.

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice.

Prasher JM, Lalai AS, Heijmans-Antonissen C, Ploemacher RE, Hoeijmakers JH, Touw IP, Niedernhofer LJ.

EMBO J. 2005 Feb 23;24(4):861-71. Epub 2005 Feb 3.

2.

GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.

Ling KW, Ottersbach K, van Hamburg JP, Oziemlak A, Tsai FY, Orkin SH, Ploemacher R, Hendriks RW, Dzierzak E.

J Exp Med. 2004 Oct 4;200(7):871-82.

3.

Addition of treosulfan to a nonmyeloablative conditioning regimen results in enhanced chimerism and immunologic tolerance in an experimental allogeneic bone marrow transplant model.

Ploemacher RE, Johnson KW, Rombouts EJ, Etienne K, Westerhof GR, Baumgart J, White-Scharf ME, Down JD.

Biol Blood Marrow Transplant. 2004 Apr;10(4):236-45.

4.

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia.

Rombouts EJ, Pavic B, Löwenberg B, Ploemacher RE.

Blood. 2004 Jul 15;104(2):550-7. Epub 2004 Mar 30.

5.

GRK6 deficiency is associated with enhanced CXCR4-mediated neutrophil chemotaxis in vitro and impaired responsiveness to G-CSF in vivo.

Vroon A, Heijnen CJ, Raatgever R, Touw IP, Ploemacher RE, Premont RT, Kavelaars A.

J Leukoc Biol. 2004 Apr;75(4):698-704. Epub 2004 Jan 2.

PMID:
14704365
6.

Toward a myeloablative regimen with clinical potential: II. Treosulfan induces specific skin graft tolerance across haploidentical MHC barriers.

van Pel M, van Breugel DW, Vos W, Ploemacher RE, Boog CJ.

Bone Marrow Transplant. 2004 Jan;33(2):153-9.

PMID:
14661037
8.
9.
10.

Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.

Oostendorp RA, Medvinsky AJ, Kusadasi N, Nakayama N, Harvey K, Orelio C, Ottersbach K, Covey T, Ploemacher RE, Saris C, Dzierzak E.

J Cell Sci. 2002 May 15;115(Pt 10):2099-108.

11.

Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity.

Oostendorp RA, Harvey KN, Kusadasi N, de Bruijn MF, Saris C, Ploemacher RE, Medvinsky AL, Dzierzak EA.

Blood. 2002 Feb 15;99(4):1183-9.

12.

The cobblestone-area-forming cell assay.

de Haan G, Ploemacher R.

Methods Mol Med. 2002;63:143-51. doi: 10.1385/1-59259-140-X:143.

PMID:
21437805
13.

Stromal support augments extended long-term ex vivo expansion of hemopoietic progenitor cells.

Kusadasi N, Koevoet JL, van Soest PL, Ploemacher RE.

Leukemia. 2001 Sep;15(9):1347-58.

15.
16.

Assays for the assessment of human hematopoietic stem cells.

de Wynter E, Ploemacher RE.

J Biol Regul Homeost Agents. 2001 Jan-Mar;15(1):23-7. Review. No abstract available.

PMID:
11388741
17.

O6-Benzylguanine potentiates BCNU but not busulfan toxicity in hematopoietic stem cells.

Westerhof GR, Down JD, Blokland I, Wood M, Boudewijn A, Watson AJ, McGown AT, Ploemacher RE, Margison GP.

Exp Hematol. 2001 May;29(5):633-8.

PMID:
11376877
18.

Stroma-supported progenitor production as a prognostic tool for graft failure following autologous stem cell transplantation.

Van Hennik PB, Breems DA, Kusadasi N, Slaper-Cortenbach IC, van den Berg H, van der Lelie HJ, Schipperus MR, Cornelissen JJ, Ploemacher RE.

Br J Haematol. 2000 Nov;111(2):674-84.

PMID:
11122121
19.

Successful short-term ex vivo expansion of NOD/SCID repopulating ability and CAFC week 6 from umbilical cord blood.

Kusadasi N, van Soest PL, Mayen AE, Koevoet JL, Ploemacher RE.

Leukemia. 2000 Nov;14(11):1944-53.

20.

Comparison of different busulfan analogues for depletion of hematopoietic stem cells and promotion of donor-type chimerism in murine bone marrow transplant recipients.

Westerhof GR, Ploemacher RE, Boudewijn A, Blokland I, Dillingh JH, McGown AT, Hadfield JA, Dawson MJ, Down JD.

Cancer Res. 2000 Oct 1;60(19):5470-8.

21.

How useful is the in vitro expansion of fetal CD34+ progenitor cells from maternal blood samples for diagnostic purposes?

Jansen MW, Korver-Hakkennes K, van Leenen D, Brandenburg H, Wildschut HI, Wladimiroff JW, Ploemacher RE.

Prenat Diagn. 2000 Sep;20(9):725-31.

PMID:
11015701
22.

Characterisation and biology of normal human haematopoietic stem cells.

Ploemacher RE.

Haematologica. 1999 Jun;84 Suppl EHA-4:4-7. Review. No abstract available.

PMID:
10907454
23.

Connexin-43 gap junctions are involved in multiconnexin-expressing stromal support of hemopoietic progenitors and stem cells.

Cancelas JA, Koevoet WL, de Koning AE, Mayen AE, Rombouts EJ, Ploemacher RE.

Blood. 2000 Jul 15;96(2):498-505.

25.
26.

Gp130-signaling synergizes with FL and TPO for the long-term expansion of cord blood progenitors.

Rappold I, Watt SM, Kusadasi N, Rose-John S, Hatzfeld J, Ploemacher RE.

Leukemia. 1999 Dec;13(12):2036-48.

28.
29.
30.
32.

Assays to determine hematopoietic stem cell content in blood or marrow grafts.

Verfaillie CM, Ploemacher R, Di Persio J, Sutherland R, Serke S, Johnsen H, Noga S, Negrin R; Stem Cell Evaluation and Manipulation Committee.

Cytotherapy. 1999;1(1):41-9. Review. No abstract available.

PMID:
19746648
33.

Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice.

van Hennik PB, Verstegen MM, Bierhuizen MF, Limón A, Wognum AW, Cancelas JA, Barquinero J, Ploemacher RE, Wagemaker G.

Blood. 1998 Dec 1;92(11):4013-22.

34.

Bone marrow cellular composition in Listeria monocytogenes infected mice detected using ER-MP12 and ER-MP20 antibodies: a flow cytometric alternative to differential counting.

de Bruijn MF, van Vianen W, Ploemacher RE, Bakker-Woudenberg IA, Campbell PA, van Ewijk W, Leenen PJ.

J Immunol Methods. 1998 Aug 1;217(1-2):27-39.

PMID:
9776572
35.

An in vitro model for cytogenetic conversion in CML. Interferon-alpha preferentially inhibits the outgrowth of malignant stem cells preserved in long-term culture.

Cornelissen JJ, Ploemacher RE, Wognum BW, Borsboom A, Kluin-Nelemans HC, Hagemeijer A, Löwenberg B.

J Clin Invest. 1998 Sep 1;102(5):976-83.

36.

Maintaining high levels of syngeneic bone marrow engraftment while omitting cyclophosphamide in busulfan-containing conditioning regimens.

Robbin Westerhof G, Ploemacher RE, Down JD.

Blood. 1998 Aug 15;92(4):1462-3. No abstract available.

38.

A nylon wool filter coated with human immunoglobulin for rapid depletion of monocytes and myeloid cells from peripheral blood stem cell transplants.

Kwekkeboom J, Buurman DE, Ploemacher RE, Baars JW, Loos HA, Slaper-Cortenbach IC.

Exp Hematol. 1998 May;26(5):400-8.

PMID:
9590656
39.

Transplantation of human umbilical cord blood cells in macrophage-depleted SCID mice: evidence for accessory cell involvement in expansion of immature CD34+CD38- cells.

Verstegen MM, van Hennik PB, Terpstra W, van den Bos C, Wielenga JJ, van Rooijen N, Ploemacher RE, Wagemaker G, Wognum AW.

Blood. 1998 Mar 15;91(6):1966-76.

40.

Thiotepa improves allogeneic bone marrow engraftment without enhancing stem cell depletion in irradiated mice.

Down JD, Westerhof GR, Boudewijn A, Setroikromo R, Ploemacher RE.

Bone Marrow Transplant. 1998 Feb;21(4):327-30.

41.

Stroma-contact prevents loss of hematopoietic stem cell quality during ex vivo expansion of CD34+ mobilized peripheral blood stem cells.

Breems DA, Blokland EA, Siebel KE, Mayen AE, Engels LJ, Ploemacher RE.

Blood. 1998 Jan 1;91(1):111-7.

42.

Stem cells: characterization and measurement.

Ploemacher RE.

Baillieres Clin Haematol. 1997 Sep;10(3):429-44. Review.

PMID:
9421609
43.

Separation of G-CSF-mobilized PBSC transplants by counterflow centrifugal elutriation: modest enrichment of CD34+ cells but no loss of primitive haemopoietic progenitors.

Kwekkeboom J, Buurman DE, van Hennik PB, Ploemacher RE, Loos HA, Slaper-Cortenbach IC.

Br J Haematol. 1997 Oct;99(1):47-55.

PMID:
9359501
44.

Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells.

Terpstra W, Rozemuller H, Breems DA, Rombouts EJ, Prins A, FitzGerald DJ, Kreitman RJ, Wielenga JJ, Ploemacher RE, Löwenberg B, Hagenbeek A, Martens AC.

Blood. 1997 Nov 1;90(9):3735-42.

45.

Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells.

Valk P, Verbakel S, Vankan Y, Hol S, Mancham S, Ploemacher R, Mayen A, Löwenberg B, Delwel R.

Blood. 1997 Aug 15;90(4):1448-57.

46.

Does transmembrane communication through gap junctions enable stem cells to overcome stromal inhibition?

Rosendaal M, Mayen A, de Koning A, Dunina-Barkovskaya T, Krenács T, Ploemacher R.

Leukemia. 1997 Aug;11(8):1281-9.

47.

The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery.

Whyatt DJ, Karis A, Harkes IC, Verkerk A, Gillemans N, Elefanty AG, Vairo G, Ploemacher R, Grosveld F, Philipsen S.

Genes Funct. 1997 Feb;1(1):11-24.

PMID:
9680325
48.
49.

Efficient long-term maintenance of chronic myeloid leukemic cobblestone area forming cells on a murine stromal cell line.

Cornelissen JJ, Wognum AW, Ploemacher RE, Frassoni F, Wagemaker G, Hagemeijer A, Löwenberg B.

Leukemia. 1997 Jan;11(1):126-33.

50.

High-level expression of the ER-MP58 antigen on mouse bone marrow hematopoietic progenitor cells marks commitment to the myeloid lineage.

de Bruijn MF, Ploemacher RE, Mayen AE, Voerman JS, Slieker WA, van Ewijk W, Leenen PJ.

Eur J Immunol. 1996 Dec;26(12):2850-8.

PMID:
8977277

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