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Items: 34


Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment.

Azizi E, Carr AJ, Plitas G, Cornish AE, Konopacki C, Prabhakaran S, Nainys J, Wu K, Kiseliovas V, Setty M, Choi K, Fromme RM, Dao P, McKenney PT, Wasti RC, Kadaveru K, Mazutis L, Rudensky AY, Pe'er D.

Cell. 2018 Aug 23;174(5):1293-1308.e36. doi: 10.1016/j.cell.2018.05.060. Epub 2018 Jun 28.


Tumor Biology Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients Presenting with Locally Advanced Breast Cancer.

Gentile LF, Plitas G, Zabor EC, Stempel M, Morrow M, Barrio AV.

Ann Surg Oncol. 2017 Dec;24(13):3896-3902. doi: 10.1245/s10434-017-6085-y. Epub 2017 Sep 15.


Axillary Dissection and Nodal Irradiation Can Be Avoided for Most Node-positive Z0011-eligible Breast Cancers: A Prospective Validation Study of 793 Patients.

Morrow M, Van Zee KJ, Patil S, Petruolo O, Mamtani A, Barrio AV, Capko D, El-Tamer M, Gemignani ML, Heerdt AS, Kirstein L, Pilewskie M, Plitas G, Sacchini VS, Sclafani LM, Ho A, Cody HS.

Ann Surg. 2017 Sep;266(3):457-462. doi: 10.1097/SLA.0000000000002354.


Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.

Plitas G, Konopacki C, Wu K, Bos PD, Morrow M, Putintseva EV, Chudakov DM, Rudensky AY.

Immunity. 2016 Nov 15;45(5):1122-1134. doi: 10.1016/j.immuni.2016.10.032.


Regulatory T Cells: Differentiation and Function.

Plitas G, Rudensky AY.

Cancer Immunol Res. 2016 Sep 2;4(9):721-5. doi: 10.1158/2326-6066.CIR-16-0193. Review.


How Often Does Neoadjuvant Chemotherapy Avoid Axillary Dissection in Patients With Histologically Confirmed Nodal Metastases? Results of a Prospective Study.

Mamtani A, Barrio AV, King TA, Van Zee KJ, Plitas G, Pilewskie M, El-Tamer M, Gemignani ML, Heerdt AS, Sclafani LM, Sacchini V, Cody HS 3rd, Patil S, Morrow M.

Ann Surg Oncol. 2016 Oct;23(11):3467-3474. doi: 10.1245/s10434-016-5246-8. Epub 2016 May 9.


Genetic and epigenetic variation in the lineage specification of regulatory T cells.

Arvey A, van der Veeken J, Plitas G, Rich SS, Concannon P, Rudensky AY.

Elife. 2015 Oct 28;4:e07571. doi: 10.7554/eLife.07571.


Skin Flap Necrosis After Mastectomy With Reconstruction: A Prospective Study.

Matsen CB, Mehrara B, Eaton A, Capko D, Berg A, Stempel M, Van Zee KJ, Pusic A, King TA, Cody HS 3rd, Pilewskie M, Cordeiro P, Sclafani L, Plitas G, Gemignani ML, Disa J, El-Tamer M, Morrow M.

Ann Surg Oncol. 2016 Jan;23(1):257-64. doi: 10.1245/s10434-015-4709-7. Epub 2015 Jul 21.


Reigning in regulatory T-cell function.

Konopacki C, Plitas G, Rudensky A.

Nat Biotechnol. 2015 Jul;33(7):718-9. doi: 10.1038/nbt.3285. No abstract available.


Extent of microinvasion in ductal carcinoma in situ is not associated with sentinel lymph node metastases.

Matsen CB, Hirsch A, Eaton A, Stempel M, Heerdt A, Van Zee KJ, Cody HS 3rd, Morrow M, Plitas G.

Ann Surg Oncol. 2014 Oct;21(10):3330-5. doi: 10.1245/s10434-014-3920-2. Epub 2014 Aug 5.


Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy.

Bos PD, Plitas G, Rudra D, Lee SY, Rudensky AY.

J Exp Med. 2013 Oct 21;210(11):2435-66. doi: 10.1084/jem.20130762. Epub 2013 Oct 14.


Axillary dissection can be avoided in the majority of clinically node-negative patients undergoing breast-conserving therapy.

Dengel LT, Van Zee KJ, King TA, Stempel M, Cody HS, El-Tamer M, Gemignani ML, Sclafani LM, Sacchini VS, Heerdt AS, Plitas G, Junqueira M, Capko D, Patil S, Morrow M.

Ann Surg Oncol. 2014 Jan;21(1):22-7. doi: 10.1245/s10434-013-3200-6. Epub 2013 Aug 22.


Controversies in the management of regional nodes in melanoma.

Plitas G, Ariyan CE.

J Natl Compr Canc Netw. 2012 Mar;10(3):414-21. Review.


Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis.

Katz SC, Ryan K, Ahmed N, Plitas G, Chaudhry UI, Kingham TP, Naheed S, Nguyen C, Somasundar P, Espat NJ, Junghans RP, Dematteo RP.

J Immunol. 2011 Aug 1;187(3):1150-6. doi: 10.4049/jimmunol.1004077. Epub 2011 Jun 22.


Neutrophil IL-10 suppresses peritoneal inflammatory monocytes during polymicrobial sepsis.

Ocuin LM, Bamboat ZM, Balachandran VP, Cavnar MJ, Obaid H, Plitas G, DeMatteo RP.

J Leukoc Biol. 2011 Mar;89(3):423-32. doi: 10.1189/jlb.0810479. Epub 2010 Nov 24.


Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion.

Bamboat ZM, Ocuin LM, Balachandran VP, Obaid H, Plitas G, DeMatteo RP.

J Clin Invest. 2010 Feb;120(2):559-69. doi: 10.1172/JCI40008. Epub 2010 Jan 19.


Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury.

Bamboat ZM, Balachandran VP, Ocuin LM, Obaid H, Plitas G, DeMatteo RP.

Hepatology. 2010 Feb;51(2):621-32. doi: 10.1002/hep.23365.


The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors.

Burt BM, Plitas G, Zhao Z, Bamboat ZM, Nguyen HM, Dupont B, DeMatteo RP.

J Immunol. 2009 Aug 1;183(3):1789-96. doi: 10.4049/jimmunol.0900541. Epub 2009 Jul 8.


Human liver dendritic cells promote T cell hyporesponsiveness.

Bamboat ZM, Stableford JA, Plitas G, Burt BM, Nguyen HM, Welles AP, Gonen M, Young JW, DeMatteo RP.

J Immunol. 2009 Feb 15;182(4):1901-11. doi: 10.4049/jimmunol.0803404.


Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits.

Brandl K, Plitas G, Mihu CN, Ubeda C, Jia T, Fleisher M, Schnabl B, DeMatteo RP, Pamer EG.

Nature. 2008 Oct 9;455(7214):804-7. doi: 10.1038/nature07250. Epub 2008 Aug 24.


CD11c identifies a subset of murine liver natural killer cells that responds to adenoviral hepatitis.

Burt BM, Plitas G, Stableford JA, Nguyen HM, Bamboat ZM, Pillarisetty VG, DeMatteo RP.

J Leukoc Biol. 2008 Oct;84(4):1039-46. doi: 10.1189/jlb.0408256. Epub 2008 Jul 29.


Circulating HLA-DR(+) natural killer cells have potent lytic ability and weak antigen-presenting cell function.

Burt BM, Plitas G, Nguyen HM, Stableford JA, Bamboat ZM, Dematteo RP.

Hum Immunol. 2008 Aug;69(8):469-74. doi: 10.1016/j.humimm.2008.06.009. Epub 2008 Jul 18.


Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis.

Plitas G, Burt BM, Nguyen HM, Bamboat ZM, DeMatteo RP.

J Exp Med. 2008 Jun 9;205(6):1277-83. doi: 10.1084/jem.20080162. Epub 2008 May 12.


Dendritic cells are required for effective cross-presentation in the murine liver.

Plitas G, Burt BM, Stableford JA, Nguyen HM, Welles AP, DeMatteo RP.

Hepatology. 2008 Apr;47(4):1343-51. doi: 10.1002/hep.22167.


NK dendritic cells expanded in IL-15 exhibit antitumor responses in vivo.

Chaudhry UI, Plitas G, Burt BM, Kingham TP, Raab JR, DeMatteo RP.

J Immunol. 2007 Oct 1;179(7):4654-60.


MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection.

Brandl K, Plitas G, Schnabl B, DeMatteo RP, Pamer EG.

J Exp Med. 2007 Aug 6;204(8):1891-900. Epub 2007 Jul 16.


NK dendritic cells are innate immune responders to Listeria monocytogenes infection.

Plitas G, Chaudhry UI, Kingham TP, Raab JR, DeMatteo RP.

J Immunol. 2007 Apr 1;178(7):4411-6.


Murine liver plasmacytoid dendritic cells become potent immunostimulatory cells after Flt-3 ligand expansion.

Kingham TP, Chaudhry UI, Plitas G, Katz SC, Raab J, DeMatteo RP.

Hepatology. 2007 Feb;45(2):445-54.


Combined stimulation with interleukin-18 and CpG induces murine natural killer dendritic cells to produce IFN-gamma and inhibit tumor growth.

Chaudhry UI, Kingham TP, Plitas G, Katz SC, Raab JR, DeMatteo RP.

Cancer Res. 2006 Nov 1;66(21):10497-504.


Left renal vein reconstruction after right nephrectomy and inadvertent left renal vein ligation: a case report and review of the literature.

Powell AC, Plitas G, Muhs BE, Stifelman M, Maldonado TS.

Vasc Endovascular Surg. 2006 Oct-Nov;40(5):421-4. Review.


Temporal expression and activation of matrix metalloproteinases-2, -9, and membrane type 1-matrix metalloproteinase following acute hindlimb ischemia.

Muhs BE, Plitas G, Delgado Y, Ianus I, Shaw JP, Adelman MA, Lamparello P, Shamamian P, Gagne P.

J Surg Res. 2003 May 1;111(1):8-15.


Experimental hindlimb ischemia increases neutrophil-mediated matrix metalloproteinase activity: a potential mechanism for lung injury after limb ischemia.

Plitas G, Gagne PJ, Muhs BE, Ianus IA, Shaw JP, Beudjekian M, Delgado Y, Jacobowitz G, Rockman C, Shamamian P.

J Am Coll Surg. 2003 May;196(5):761-7.


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