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Items: 1 to 50 of 165

1.

Capillary flow disturbances after experimental subarachnoid hemorrhage: a contributor to delayed cerebral ischemia?

Anzabi M, Angleys H, Aamand R, Ardalan M, Mouridsen K, Rasmussen PM, Sørensen JCH, Plesnila N, Østergaard L, Iversen NK.

Microcirculation. 2018 Nov 15:e12516. doi: 10.1111/micc.12516. [Epub ahead of print]

PMID:
30431201
2.

Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury.

Frik J, Merl-Pham J, Plesnila N, Mattugini N, Kjell J, Kraska J, Gómez RM, Hauck SM, Sirko S, Götz M.

EMBO Rep. 2018 May;19(5). pii: e45294. doi: 10.15252/embr.201745294. Epub 2018 Apr 9.

3.

Microvasospasms After Experimental Subarachnoid Hemorrhage Do Not Depend on Endothelin A Receptors.

Liu H, Dienel A, Schöller K, Schwarzmaier SM, Nehrkorn K, Plesnila N, Terpolilli NA.

Stroke. 2018 Mar;49(3):693-699. doi: 10.1161/STROKEAHA.117.020028. Epub 2018 Feb 8.

PMID:
29438081
4.

Cylindromatosis mediates neuronal cell death in vitro and in vivo.

Ganjam GK, Terpolilli NA, Diemert S, Eisenbach I, Hoffmann L, Reuther C, Herden C, Roth J, Plesnila N, Culmsee C.

Cell Death Differ. 2018 Aug;25(8):1394-1407. doi: 10.1038/s41418-017-0046-7. Epub 2018 Jan 19.

PMID:
29352268
5.

Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.

Bischof H, Rehberg M, Stryeck S, Artinger K, Eroglu E, Waldeck-Weiermair M, Gottschalk B, Rost R, Deak AT, Niedrist T, Vujic N, Lindermuth H, Prassl R, Pelzmann B, Groschner K, Kratky D, Eller K, Rosenkranz AR, Madl T, Plesnila N, Graier WF, Malli R.

Nat Commun. 2017 Nov 10;8(1):1422. doi: 10.1038/s41467-017-01615-z.

6.

Decreased Secondary Lesion Growth and Attenuated Immune Response after Traumatic Brain Injury in Tlr2/4-/- Mice.

Krieg SM, Voigt F, Knuefermann P, Kirschning CJ, Plesnila N, Ringel F.

Front Neurol. 2017 Aug 30;8:455. doi: 10.3389/fneur.2017.00455. eCollection 2017.

7.

The choroid plexus is a key cerebral invasion route for T cells after stroke.

Llovera G, Benakis C, Enzmann G, Cai R, Arzberger T, Ghasemigharagoz A, Mao X, Malik R, Lazarevic I, Liebscher S, Ertürk A, Meissner L, Vivien D, Haffner C, Plesnila N, Montaner J, Engelhardt B, Liesz A.

Acta Neuropathol. 2017 Dec;134(6):851-868. doi: 10.1007/s00401-017-1758-y. Epub 2017 Jul 31.

PMID:
28762187
8.

RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke.

Tiedt S, Prestel M, Malik R, Schieferdecker N, Duering M, Kautzky V, Stoycheva I, Böck J, Northoff BH, Klein M, Dorn F, Krohn K, Teupser D, Liesz A, Plesnila N, Holdt LM, Dichgans M.

Circ Res. 2017 Sep 29;121(8):970-980. doi: 10.1161/CIRCRESAHA.117.311572. Epub 2017 Jul 19.

PMID:
28724745
9.

Inversion of neurovascular coupling after subarachnoid hemorrhage in vivo.

Balbi M, Koide M, Wellman GC, Plesnila N.

J Cereb Blood Flow Metab. 2017 Nov;37(11):3625-3634. doi: 10.1177/0271678X16686595. Epub 2017 Jan 23.

10.

Recent progress in translational research on neurovascular and neurodegenerative disorders.

Demuth HU, Dijkhuizen RM, Farr TD, Gelderblom M, Horsburgh K, Iadecola C, Mcleod DD, Michalski D, Murphy TH, Orbe J, Otte WM, Petzold GC, Plesnila N, Reiser G, Reymann KG, Rueger MA, Saur D, Savitz SI, Schilling S, Spratt NJ, Turner RJ, Vemuganti R, Vivien D, Yepes M, Zille M, Boltze J; ISN&N meeting contributors.

Restor Neurol Neurosci. 2017;35(1):87-103. doi: 10.3233/RNN-160690. Review.

11.

Time-Dependent Effects of Arginine-Vasopressin V1 Receptor Inhibition on Secondary Brain Damage after Traumatic Brain Injury.

Krieg SM, Trabold R, Plesnila N.

J Neurotrauma. 2017 Apr 1;34(7):1329-1336. doi: 10.1089/neu.2016.4514. Epub 2016 Dec 6.

PMID:
27762660
12.

Shrinkage-mediated imaging of entire organs and organisms using uDISCO.

Pan C, Cai R, Quacquarelli FP, Ghasemigharagoz A, Lourbopoulos A, Matryba P, Plesnila N, Dichgans M, Hellal F, Ertürk A.

Nat Methods. 2016 Oct;13(10):859-67. doi: 10.1038/nmeth.3964. Epub 2016 Aug 22.

PMID:
27548807
13.

Inadequate food and water intake determine mortality following stroke in mice.

Lourbopoulos A, Mamrak U, Roth S, Balbi M, Shrouder J, Liesz A, Hellal F, Plesnila N.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2084-2097. doi: 10.1177/0271678X16660986. Epub 2016 Jan 1.

14.

Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines.

Boltze J, Wagner DC, Henninger N, Plesnila N, Ayata C.

Transl Stroke Res. 2016 Aug;7(4):241-7. doi: 10.1007/s12975-016-0474-6. Epub 2016 Jun 14.

15.

Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons.

Osterstock G, Mitutsova V, Barre A, Granier M, Fontanaud P, Chazalon M, Carmignac D, Robinson IC, Low MJ, Plesnila N, Hodson DJ, Mollard P, Méry PF.

Sci Rep. 2016 Apr 13;6:24394. doi: 10.1038/srep24394.

16.

The Formation of Microthrombi in Parenchymal Microvessels after Traumatic Brain Injury Is Independent of Coagulation Factor XI.

Schwarzmaier SM, de Chaumont C, Balbi M, Terpolilli NA, Kleinschnitz C, Gruber A, Plesnila N.

J Neurotrauma. 2016 Sep 1;33(17):1634-44. doi: 10.1089/neu.2015.4173. Epub 2016 Feb 17.

17.

Acute changes in neurovascular reactivity after subarachnoid hemorrhage in vivo.

Balbi M, Koide M, Schwarzmaier SM, Wellman GC, Plesnila N.

J Cereb Blood Flow Metab. 2017 Jan;37(1):178-187. Epub 2015 Dec 16.

18.

Nitric oxide inhalation reduces brain damage, prevents mortality, and improves neurological outcome after subarachnoid hemorrhage by resolving early pial microvasospasms.

Terpolilli NA, Feiler S, Dienel A, Müller F, Heumos N, Friedrich B, Stover J, Thal S, Schöller K, Plesnila N.

J Cereb Blood Flow Metab. 2016 Dec;36(12):2096-2107. Epub 2015 Nov 2.

19.

The immune system in traumatic brain injury.

Plesnila N.

Curr Opin Pharmacol. 2016 Feb;26:110-7. doi: 10.1016/j.coph.2015.10.008. Epub 2015 Nov 21. Review.

PMID:
26613129
20.

Temporal Profile of MicroRNA Expression in Contused Cortex after Traumatic Brain Injury in Mice.

Meissner L, Gallozzi M, Balbi M, Schwarzmaier S, Tiedt S, Terpolilli NA, Plesnila N.

J Neurotrauma. 2016 Apr 15;33(8):713-20. doi: 10.1089/neu.2015.4077. Epub 2015 Dec 23.

PMID:
26426744
21.

Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

Ghosh M, Balbi M, Hellal F, Dichgans M, Lindauer U, Plesnila N.

Ann Neurol. 2015 Dec;78(6):887-900. doi: 10.1002/ana.24512. Epub 2015 Oct 7.

PMID:
26312599
22.

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.

Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A.

Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853.

PMID:
26246166
23.

Are We Barking Up the Wrong Vessels? Cerebral Microcirculation After Subarachnoid Hemorrhage.

Terpolilli NA, Brem C, Bühler D, Plesnila N.

Stroke. 2015 Oct;46(10):3014-9. doi: 10.1161/STROKEAHA.115.006353. Epub 2015 Jul 7. Review. No abstract available.

PMID:
26152299
24.

Dysfunction of mouse cerebral arteries during early aging.

Balbi M, Ghosh M, Longden TA, Jativa Vega M, Gesierich B, Hellal F, Lourbopoulos A, Nelson MT, Plesnila N.

J Cereb Blood Flow Metab. 2015 Sep;35(9):1445-53. doi: 10.1038/jcbfm.2015.107. Epub 2015 Jun 10.

25.

Applying the retro-enantio approach to obtain a peptide capable of overcoming the blood-brain barrier.

Prades R, Oller-Salvia B, Schwarzmaier SM, Selva J, Moros M, Balbi M, Grazú V, de La Fuente JM, Egea G, Plesnila N, Teixidó M, Giralt E.

Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3967-72. doi: 10.1002/anie.201411408. Epub 2015 Feb 4.

PMID:
25650865
26.

Bax regulates neuronal Ca2+ homeostasis.

D'Orsi B, Kilbride SM, Chen G, Perez Alvarez S, Bonner HP, Pfeiffer S, Plesnila N, Engel T, Henshall DC, Düssmann H, Prehn JH.

J Neurosci. 2015 Jan 28;35(4):1706-22. doi: 10.1523/JNEUROSCI.2453-14.2015.

27.

Effect of decompressive craniectomy on outcome following subarachnoid hemorrhage in mice.

Bühler D, Azghandi S, Schüller K, Plesnila N.

Stroke. 2015 Mar;46(3):819-26. doi: 10.1161/STROKEAHA.114.007703. Epub 2015 Jan 15.

PMID:
25593134
28.

Identification of the Vascular Source of Vasogenic Brain Edema following Traumatic Brain Injury Using In Vivo 2-Photon Microscopy in Mice.

Schwarzmaier SM, Gallozzi M, Plesnila N.

J Neurotrauma. 2015 Jul 1;32(13):990-1000. doi: 10.1089/neu.2014.3775. Epub 2015 Apr 15.

PMID:
25585052
29.

Contributions of the immune system to the pathophysiology of traumatic brain injury - evidence by intravital microscopy.

Schwarzmaier SM, Plesnila N.

Front Cell Neurosci. 2014 Nov 4;8:358. doi: 10.3389/fncel.2014.00358. eCollection 2014. Review.

30.

Endothelial nitric oxide synthase mediates arteriolar vasodilatation after traumatic brain injury in mice.

Schwarzmaier SM, Terpolilli NA, Dienel A, Gallozzi M, Schinzel R, Tegtmeier F, Plesnila N.

J Neurotrauma. 2015 May 15;32(10):731-8. doi: 10.1089/neu.2014.3650. Epub 2015 Feb 25.

PMID:
25363688
31.

The neuroprotective effect of 17β-estradiol is independent of its antioxidative properties.

Gröger M, Plesnila N.

Brain Res. 2014 Nov 17;1589:61-7. doi: 10.1016/j.brainres.2014.08.029. Epub 2014 Aug 20.

PMID:
25148707
32.

Modeling stroke in mice: permanent coagulation of the distal middle cerebral artery.

Llovera G, Roth S, Plesnila N, Veltkamp R, Liesz A.

J Vis Exp. 2014 Jul 31;(89):e51729. doi: 10.3791/51729.

33.

Protocol for the induction of subarachnoid hemorrhage in mice by perforation of the Circle of Willis with an endovascular filament.

Bühler D, Schüller K, Plesnila N.

Transl Stroke Res. 2014 Dec;5(6):653-9. doi: 10.1007/s12975-014-0366-6. Epub 2014 Aug 16.

34.

Effect of small molecule vasopressin V1a and V2 receptor antagonists on brain edema formation and secondary brain damage following traumatic brain injury in mice.

Krieg SM, Sonanini S, Plesnila N, Trabold R.

J Neurotrauma. 2015 Feb 15;32(4):221-7. doi: 10.1089/neu.2013.3274. Epub 2014 Dec 16.

35.

CO2 has no therapeutic effect on early microvasospasm after experimental subarachnoid hemorrhage.

Friedrich B, Michalik R, Oniszczuk A, Abubaker K, Kozniewska E, Plesnila N.

J Cereb Blood Flow Metab. 2014 Aug;34(8):e1-6. doi: 10.1038/jcbfm.2014.96. Epub 2014 May 28.

36.

Sustained alterations of hypothalamic tanycytes during posttraumatic hypopituitarism in male mice.

Osterstock G, El Yandouzi T, Romanò N, Carmignac D, Langlet F, Coutry N, Guillou A, Schaeffer M, Chauvet N, Vanacker C, Galibert E, Dehouck B, Robinson IC, Prévot V, Mollard P, Plesnila N, Méry PF.

Endocrinology. 2014 May;155(5):1887-98. doi: 10.1210/en.2013-1336. Epub 2014 Mar 6.

PMID:
24601879
37.

Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons.

Dolga AM, de Andrade A, Meissner L, Knaus HG, Höllerhage M, Christophersen P, Zischka H, Plesnila N, Höglinger GU, Culmsee C.

Cell Death Dis. 2014 Jan 16;5:e999. doi: 10.1038/cddis.2013.530.

38.

Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress.

Doti N, Reuther C, Scognamiglio PL, Dolga AM, Plesnila N, Ruvo M, Culmsee C.

Cell Death Dis. 2014 Jan 16;5:e993. doi: 10.1038/cddis.2013.518.

39.

Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines.

Boltze J, Ayata C, Wagner DC, Plesnila N.

Stroke. 2014 Feb;45(2):357. doi: 10.1161/STROKEAHA.113.004148. Epub 2014 Jan 9. No abstract available.

40.

Inhaled nitric oxide protects males but not females from neonatal mouse hypoxia-ischemia brain injury.

Zhu C, Sun Y, Gao J, Wang X, Plesnila N, Blomgren K.

Transl Stroke Res. 2013 Apr;4(2):201-7. doi: 10.1007/s12975-012-0217-2. Epub 2012 Oct 20.

PMID:
24323275
41.

A murine model of subarachnoid hemorrhage.

Schüller K, Bühler D, Plesnila N.

J Vis Exp. 2013 Nov 21;(81):e50845. doi: 10.3791/50845.

42.

A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies.

Schmitt S, Saathoff F, Meissner L, Schropp EM, Lichtmannegger J, Schulz S, Eberhagen C, Borchard S, Aichler M, Adamski J, Plesnila N, Rothenfusser S, Kroemer G, Zischka H.

Anal Biochem. 2013 Dec 1;443(1):66-74. doi: 10.1016/j.ab.2013.08.007. Epub 2013 Aug 19.

PMID:
23969012
43.

The delayed addition of human mesenchymal stem cells to pre-formed endothelial cell networks results in functional vascularization of a collagen-glycosaminoglycan scaffold in vivo.

McFadden TM, Duffy GP, Allen AB, Stevens HY, Schwarzmaier SM, Plesnila N, Murphy JM, Barry FP, Guldberg RE, O'Brien FJ.

Acta Biomater. 2013 Dec;9(12):9303-16. doi: 10.1016/j.actbio.2013.08.014. Epub 2013 Aug 17.

PMID:
23958783
44.

Pathophysiological Role of Global Cerebral Ischemia following Subarachnoid Hemorrhage: The Current Experimental Evidence.

Plesnila N.

Stroke Res Treat. 2013;2013:651958. doi: 10.1155/2013/651958. Epub 2013 Jun 12.

45.

Bradykinin in blood and cerebrospinal fluid after acute cerebral lesions: correlations with cerebral edema and intracranial pressure.

Kunz M, Nussberger J, Holtmannspötter M, Bitterling H, Plesnila N, Zausinger S.

J Neurotrauma. 2013 Oct 1;30(19):1638-44. doi: 10.1089/neu.2012.2774.

PMID:
23638655
46.

Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected].

Sirko S, Behrendt G, Johansson PA, Tripathi P, Costa M, Bek S, Heinrich C, Tiedt S, Colak D, Dichgans M, Fischer IR, Plesnila N, Staufenbiel M, Haass C, Snapyan M, Saghatelyan A, Tsai LH, Fischer A, Grobe K, Dimou L, Götz M.

Cell Stem Cell. 2013 Apr 4;12(4):426-39. doi: 10.1016/j.stem.2013.01.019. Erratum in: Cell Stem Cell. 2013 May 2;12(5):629.

47.

In vivo temporal and spatial profile of leukocyte adhesion and migration after experimental traumatic brain injury in mice.

Schwarzmaier SM, Zimmermann R, McGarry NB, Trabold R, Kim SW, Plesnila N.

J Neuroinflammation. 2013 Feb 28;10:32. doi: 10.1186/1742-2094-10-32.

48.

Arginine vasopressin V1a receptor-deficient mice have reduced brain edema and secondary brain damage following traumatic brain injury.

Rauen K, Trabold R, Brem C, Terpolilli NA, Plesnila N.

J Neurotrauma. 2013 Aug 15;30(16):1442-8. doi: 10.1089/neu.2012.2807. Epub 2013 Jul 20.

PMID:
23441636
49.

Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.

Dolga AM, Netter MF, Perocchi F, Doti N, Meissner L, Tobaben S, Grohm J, Zischka H, Plesnila N, Decher N, Culmsee C.

J Biol Chem. 2013 Apr 12;288(15):10792-804. doi: 10.1074/jbc.M113.453522. Epub 2013 Feb 19.

50.

Inhaled nitric oxide reduces secondary brain damage after traumatic brain injury in mice.

Terpolilli NA, Kim SW, Thal SC, Kuebler WM, Plesnila N.

J Cereb Blood Flow Metab. 2013 Feb;33(2):311-8. doi: 10.1038/jcbfm.2012.176. Epub 2012 Nov 28.

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