Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 73

1.

Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview.

Mostafa A, Abdelwhab EM, Mettenleiter TC, Pleschka S.

Viruses. 2018 Sep 13;10(9). pii: E497. doi: 10.3390/v10090497. Review.

2.

NS Segment of a 1918 Influenza A Virus-Descendent Enhances Replication of H1N1pdm09 and Virus-Induced Cellular Immune Response in Mammalian and Avian Systems.

Petersen H, Mostafa A, Tantawy MA, Iqbal AA, Hoffmann D, Tallam A, Selvakumar B, Pessler F, Beer M, Rautenschlein S, Pleschka S.

Front Microbiol. 2018 Mar 22;9:526. doi: 10.3389/fmicb.2018.00526. eCollection 2018.

3.

Targeting intracellular signaling as an antiviral strategy: aerosolized LASAG for the treatment of influenza in hospitalized patients.

Scheuch G, Canisius S, Nocker K, Hofmann T, Naumann R, Pleschka S, Ludwig S, Welte T, Planz O.

Emerg Microbes Infect. 2018 Mar 7;7(1):21. doi: 10.1038/s41426-018-0023-3.

4.

Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells.

Shah Mahmud R, Mostafa A, Müller C, Kanrai P, Ulyanova V, Sokurenko Y, Dzieciolowski J, Kuznetsova I, Ilinskaya O, Pleschka S.

Virol J. 2018 Jan 5;15(1):5. doi: 10.1186/s12985-017-0915-1.

5.

Influenza H3N2 Vaccines: Recent Challenges.

Mostafa A, Pleschka S.

Trends Microbiol. 2018 Feb;26(2):87-89. doi: 10.1016/j.tim.2017.12.003.

PMID:
29268980
6.

Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.

Müller C, Schulte FW, Lange-Grünweller K, Obermann W, Madhugiri R, Pleschka S, Ziebuhr J, Hartmann RK, Grünweller A.

Antiviral Res. 2018 Feb;150:123-129. doi: 10.1016/j.antiviral.2017.12.010. Epub 2017 Dec 16.

PMID:
29258862
7.

Inhibition of Cytosolic Phospholipase A2α Impairs an Early Step of Coronavirus Replication in Cell Culture.

Müller C, Hardt M, Schwudke D, Neuman BW, Pleschka S, Ziebuhr J.

J Virol. 2018 Jan 30;92(4). pii: e01463-17. doi: 10.1128/JVI.01463-17. Print 2018 Feb 15.

8.

Targeting an Oncolytic Influenza A Virus to Tumor Tissue by Elastase.

Kuznetsova I, Arnold T, Aschacher T, Schwager C, Hegedus B, Garay T, Stukova M, Pisareva M, Pleschka S, Bergmann M, Egorov A.

Mol Ther Oncolytics. 2017 Sep 8;7:37-44. doi: 10.1016/j.omto.2017.09.002. eCollection 2017 Dec 15.

9.

Ribonuclease from Bacillus Acts as an Antiviral Agent against Negative- and Positive-Sense Single Stranded Human Respiratory RNA Viruses.

Shah Mahmud R, Müller C, Romanova Y, Mostafa A, Ulyanova V, Pleschka S, Ilinskaya O.

Biomed Res Int. 2017;2017:5279065. doi: 10.1155/2017/5279065. Epub 2017 May 4.

10.

The MEK-inhibitor CI-1040 displays a broad anti-influenza virus activity in vitro and provides a prolonged treatment window compared to standard of care in vivo.

Haasbach E, Müller C, Ehrhardt C, Schreiber A, Pleschka S, Ludwig S, Planz O.

Antiviral Res. 2017 Jun;142:178-184. doi: 10.1016/j.antiviral.2017.03.024. Epub 2017 Apr 2.

11.

Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR.

Schierhorn KL, Jolmes F, Bespalowa J, Saenger S, Peteranderl C, Dzieciolowski J, Mielke M, Budt M, Pleschka S, Herrmann A, Herold S, Wolff T.

J Virol. 2017 Apr 28;91(10). pii: e00198-17. doi: 10.1128/JVI.00198-17. Print 2017 May 15.

12.

Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems.

Kanrai P, Mostafa A, Madhugiri R, Lechner M, Wilk E, Schughart K, Ylösmäki L, Saksela K, Ziebuhr J, Pleschka S.

J Gen Virol. 2016 Sep;97(9):2135-48. doi: 10.1099/jgv.0.000542. Epub 2016 Jul 12.

PMID:
27405649
13.

The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB.

Dam S, Kracht M, Pleschka S, Schmitz ML.

J Virol. 2016 Aug 12;90(17):7980-90. doi: 10.1128/JVI.00946-16. Print 2016 Sep 1.

14.

Correction: Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia.

Högner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S.

PLoS Pathog. 2016 Jun 15;12(6):e1005716. doi: 10.1371/journal.ppat.1005716. eCollection 2016 Jun.

15.

Macrophage-epithelial paracrine crosstalk inhibits lung edema clearance during influenza infection.

Peteranderl C, Morales-Nebreda L, Selvakumar B, Lecuona E, Vadász I, Morty RE, Schmoldt C, Bespalowa J, Wolff T, Pleschka S, Mayer K, Gattenloehner S, Fink L, Lohmeyer J, Seeger W, Sznajder JI, Mutlu GM, Budinger GR, Herold S.

J Clin Invest. 2016 Apr 1;126(4):1566-80. doi: 10.1172/JCI83931. Epub 2016 Mar 21.

16.

Phylogenetic analysis of human influenza A/H3N2 viruses isolated in 2015 in Germany indicates significant genetic divergence from vaccine strains.

Mostafa A, Abdelwhab el-SM, Slanina H, Hussein MA, Kuznetsova I, Schüttler CG, Ziebuhr J, Pleschka S.

Arch Virol. 2016 Jun;161(6):1505-15. doi: 10.1007/s00705-016-2815-x. Epub 2016 Mar 14.

PMID:
26973232
17.

Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on.

Abdelwhab EM, Hassan MK, Abdel-Moneim AS, Naguib MM, Mostafa A, Hussein ITM, Arafa A, Erfan AM, Kilany WH, Agour MG, El-Kanawati Z, Hussein HA, Selim AA, Kholousy S, El-Naggar H, El-Zoghby EF, Samy A, Iqbal M, Eid A, Ibraheem EM, Pleschka S, Veits J, Nasef SA, Beer M, Mettenleiter TC, Grund C, Ali MM, Harder TC, Hafez HM.

Infect Genet Evol. 2016 Jun;40:80-90. doi: 10.1016/j.meegid.2016.02.023. Epub 2016 Feb 23. Review.

PMID:
26917362
18.

The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs.

Mostafa A, Kanrai P, Ziebuhr J, Pleschka S.

J Gen Virol. 2016 Mar;97(3):620-31. doi: 10.1099/jgv.0.000390. Epub 2016 Jan 7.

PMID:
26743314
19.

Effect of an Echinacea-Based Hot Drink Versus Oseltamivir in Influenza Treatment: A Randomized, Double-Blind, Double-Dummy, Multicenter, Noninferiority Clinical Trial.

Rauš K, Pleschka S, Klein P, Schoop R, Fisher P.

Curr Ther Res Clin Exp. 2015 Apr 20;77:66-72. doi: 10.1016/j.curtheres.2015.04.001. eCollection 2015 Dec.

20.

In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses.

Schmier S, Mostafa A, Haarmann T, Bannert N, Ziebuhr J, Veljkovic V, Dietrich U, Pleschka S.

Sci Rep. 2015 Jun 19;5:11434. doi: 10.1038/srep11434.

21.

Influenza virus-induced caspase-dependent enlargement of nuclear pores promotes nuclear export of viral ribonucleoprotein complexes.

Mühlbauer D, Dzieciolowski J, Hardt M, Hocke A, Schierhorn KL, Mostafa A, Müller C, Wisskirchen C, Herold S, Wolff T, Ziebuhr J, Pleschka S.

J Virol. 2015 Jun;89(11):6009-21. doi: 10.1128/JVI.03531-14. Epub 2015 Mar 25.

22.

Efficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments.

Mostafa A, Kanrai P, Petersen H, Ibrahim S, Rautenschlein S, Pleschka S.

PLoS One. 2015 Jan 23;10(1):e0116917. doi: 10.1371/journal.pone.0116917. eCollection 2015.

23.

Origin of the European avian-like swine influenza viruses.

Krumbholz A, Lange J, Sauerbrei A, Groth M, Platzer M, Kanrai P, Pleschka S, Scholtissek C, Büttner M, Dürrwald R, Zell R.

J Gen Virol. 2014 Nov;95(Pt 11):2372-6. doi: 10.1099/vir.0.068569-0. Epub 2014 Jul 29.

PMID:
25073465
24.

Activation of c-jun N-terminal kinase upon influenza A virus (IAV) infection is independent of pathogen-related receptors but dependent on amino acid sequence variations of IAV NS1.

Nacken W, Anhlan D, Hrincius ER, Mostafa A, Wolff T, Sadewasser A, Pleschka S, Ehrhardt C, Ludwig S.

J Virol. 2014 Aug;88(16):8843-52. doi: 10.1128/JVI.00424-14. Epub 2014 May 28.

25.

The genome of an influenza virus from a pilot whale: relation to influenza viruses of gulls and marine mammals.

Groth M, Lange J, Kanrai P, Pleschka S, Scholtissek C, Krumbholz A, Platzer M, Sauerbrei A, Zell R.

Infect Genet Evol. 2014 Jun;24:183-6. doi: 10.1016/j.meegid.2014.03.026. Epub 2014 Apr 3.

PMID:
24704761
26.

The NS segment of H5N1 avian influenza viruses (AIV) enhances the virulence of an H7N1 AIV in chickens.

Vergara-Alert J, Busquets N, Ballester M, Chaves AJ, Rivas R, Dolz R, Wang Z, Pleschka S, Majó N, Rodríguez F, Darji A.

Vet Res. 2014 Jan 25;45:7. doi: 10.1186/1297-9716-45-7.

27.

Circulation of classical swine influenza virus in Europe between the wars?

Lange J, Groth M, Kanrai P, Pleschka S, Scholtissek C, Dürrwald R, Platzer M, Sauerbrei A, Zell R.

Arch Virol. 2014 Jun;159(6):1467-73. doi: 10.1007/s00705-013-1950-x. Epub 2013 Dec 15.

PMID:
24337721
28.

Improved dual promotor-driven reverse genetics system for influenza viruses.

Mostafa A, Kanrai P, Ziebuhr J, Pleschka S.

J Virol Methods. 2013 Nov;193(2):603-10. doi: 10.1016/j.jviromet.2013.07.021. Epub 2013 Jul 22.

PMID:
23886561
29.

Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.

Högner K, Wolff T, Pleschka S, Plog S, Gruber AD, Kalinke U, Walmrath HD, Bodner J, Gattenlöhner S, Lewe-Schlosser P, Matrosovich M, Seeger W, Lohmeyer J, Herold S.

PLoS Pathog. 2013 Feb;9(2):e1003188. doi: 10.1371/journal.ppat.1003188. Epub 2013 Feb 28. Erratum in: PLoS Pathog. 2016 Jun;12(6):e1005716.

30.

Reassortment of NS segments modifies highly pathogenic avian influenza virus interaction with avian hosts and host cells.

Petersen H, Wang Z, Lenz E, Pleschka S, Rautenschlein S.

J Virol. 2013 May;87(10):5362-71. doi: 10.1128/JVI.02969-12. Epub 2013 Mar 6.

31.

Overview of influenza viruses.

Pleschka S.

Curr Top Microbiol Immunol. 2013;370:1-20. doi: 10.1007/82_2012_272. Review.

PMID:
23124938
32.

Replication and adaptive mutations of low pathogenic avian influenza viruses in tracheal organ cultures of different avian species.

Petersen H, Matrosovich M, Pleschka S, Rautenschlein S.

PLoS One. 2012;7(8):e42260. doi: 10.1371/journal.pone.0042260. Epub 2012 Aug 13.

33.

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury.

Herold S, Ludwig S, Pleschka S, Wolff T.

J Leukoc Biol. 2012 Jul;92(1):75-82. doi: 10.1189/jlb.1011530. Epub 2012 Feb 17. Review.

PMID:
22345705
34.

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo.

Droebner K, Pleschka S, Ludwig S, Planz O.

Antiviral Res. 2011 Nov;92(2):195-203. doi: 10.1016/j.antiviral.2011.08.002. Epub 2011 Aug 11.

PMID:
21854809
35.

Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo.

Pinto R, Herold S, Cakarova L, Hoegner K, Lohmeyer J, Planz O, Pleschka S.

Antiviral Res. 2011 Oct;92(1):45-56. doi: 10.1016/j.antiviral.2011.05.009. Epub 2011 May 27.

PMID:
21641936
36.

CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry.

Liu S, Li R, Zhang R, Chan CC, Xi B, Zhu Z, Yang J, Poon VK, Zhou J, Chen M, Münch J, Kirchhoff F, Pleschka S, Haarmann T, Dietrich U, Pan C, Du L, Jiang S, Zheng B.

Eur J Pharmacol. 2011 Jun 25;660(2-3):460-7. doi: 10.1016/j.ejphar.2011.04.013. Epub 2011 Apr 22.

PMID:
21536025
37.

Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses.

Krawitz C, Mraheil MA, Stein M, Imirzalioglu C, Domann E, Pleschka S, Hain T.

BMC Complement Altern Med. 2011 Feb 25;11:16. doi: 10.1186/1472-6882-11-16.

38.

NS reassortment of an H7-type highly pathogenic avian influenza virus affects its propagation by altering the regulation of viral RNA production and antiviral host response.

Wang Z, Robb NC, Lenz E, Wolff T, Fodor E, Pleschka S.

J Virol. 2010 Nov;84(21):11323-35. doi: 10.1128/JVI.01034-10. Epub 2010 Aug 25.

39.

The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIV.

Ma W, Brenner D, Wang Z, Dauber B, Ehrhardt C, Högner K, Herold S, Ludwig S, Wolff T, Yu K, Richt JA, Planz O, Pleschka S.

J Virol. 2010 Feb;84(4):2122-33. doi: 10.1128/JVI.01668-09. Epub 2009 Dec 9.

41.

Borna disease virus: a unique pathogen and its interaction with intracellular signalling pathways.

Planz O, Pleschka S, Wolff T.

Cell Microbiol. 2009 Jun;11(6):872-9. doi: 10.1111/j.1462-5822.2009.01310.x. Epub 2009 Mar 12. Review.

PMID:
19290912
42.

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand.

Herold S, Steinmueller M, von Wulffen W, Cakarova L, Pinto R, Pleschka S, Mack M, Kuziel WA, Corazza N, Brunner T, Seeger W, Lohmeyer J.

J Exp Med. 2008 Dec 22;205(13):3065-77. doi: 10.1084/jem.20080201. Epub 2008 Dec 8.

43.

RNA viruses and the mitogenic Raf/MEK/ERK signal transduction cascade.

Pleschka S.

Biol Chem. 2008 Oct;389(10):1273-82. doi: 10.1515/BC.2008.145. Review.

PMID:
18713014
44.
45.

Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity.

Mazur I, Wurzer WJ, Ehrhardt C, Pleschka S, Puthavathana P, Silberzahn T, Wolff T, Planz O, Ludwig S.

Cell Microbiol. 2007 Jul;9(7):1683-94. Epub 2007 Feb 23.

PMID:
17324159
46.

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses.

Ehrhardt C, Wolff T, Pleschka S, Planz O, Beermann W, Bode JG, Schmolke M, Ludwig S.

J Virol. 2007 Apr;81(7):3058-67. Epub 2007 Jan 17.

47.

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence.

Ehrhardt C, Marjuki H, Wolff T, Nürnberg B, Planz O, Pleschka S, Ludwig S.

Cell Microbiol. 2006 Aug;8(8):1336-48.

PMID:
16882036
48.

Alveolar epithelial cells direct monocyte transepithelial migration upon influenza virus infection: impact of chemokines and adhesion molecules.

Herold S, von Wulffen W, Steinmueller M, Pleschka S, Kuziel WA, Mack M, Srivastava M, Seeger W, Maus UA, Lohmeyer J.

J Immunol. 2006 Aug 1;177(3):1817-24.

49.

An inducible T7 RNA polymerase-dependent plasmid system.

Hamdorf M, Muckenfuss H, Tschulena U, Pleschka S, Sanzenbacher R, Cichutek K, Flory E.

Mol Biotechnol. 2006 May;33(1):13-21.

PMID:
16691002
50.

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling.

Marjuki H, Alam MI, Ehrhardt C, Wagner R, Planz O, Klenk HD, Ludwig S, Pleschka S.

J Biol Chem. 2006 Jun 16;281(24):16707-15. Epub 2006 Apr 11.

Supplemental Content

Loading ...
Support Center