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Items: 5


Exposure of clinical MRSA heterogeneous strains to β-lactams redirects metabolism to optimize energy production through the TCA cycle.

Keaton MA, Rosato RR, Plata KB, Singh CR, Rosato AE.

PLoS One. 2013 Aug 5;8(8):e71025. doi: 10.1371/journal.pone.0071025. Print 2013.


Targeting of PBP1 by β-lactams determines recA/SOS response activation in heterogeneous MRSA clinical strains.

Plata KB, Riosa S, Singh CR, Rosato RR, Rosato AE.

PLoS One. 2013 Apr 23;8(4):e61083. doi: 10.1371/journal.pone.0061083. Print 2013.


β-Lactams increase the antibacterial activity of daptomycin against clinical methicillin-resistant Staphylococcus aureus strains and prevent selection of daptomycin-resistant derivatives.

Mehta S, Singh C, Plata KB, Chanda PK, Paul A, Riosa S, Rosato RR, Rosato AE.

Antimicrob Agents Chemother. 2012 Dec;56(12):6192-200. doi: 10.1128/AAC.01525-12. Epub 2012 Sep 17.


VraSR two-component regulatory system contributes to mprF-mediated decreased susceptibility to daptomycin in in vivo-selected clinical strains of methicillin-resistant Staphylococcus aureus.

Mehta S, Cuirolo AX, Plata KB, Riosa S, Silverman JA, Rubio A, Rosato RR, Rosato AE.

Antimicrob Agents Chemother. 2012 Jan;56(1):92-102. doi: 10.1128/AAC.00432-10. Epub 2011 Oct 10.


Fate of mutation rate depends on agr locus expression during oxacillin-mediated heterogeneous-homogeneous selection in methicillin-resistant Staphylococcus aureus clinical strains.

Plata KB, Rosato RR, Rosato AE.

Antimicrob Agents Chemother. 2011 Jul;55(7):3176-86. doi: 10.1128/AAC.01119-09. Epub 2011 May 2.

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