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Items: 1 to 50 of 301

1.

Fetal hemoglobin induction during decitabine treatment of elderly high-risk myelodysplastic syndrome and acute myeloid leukemia patients: a potential dynamic biomarker for outcome.

Stomper J, Ihorst G, Suciu S, Sander PN, Becker H, Wijermans PW, Plass C, Weichenhan D, Bissé E, Claus R, Lübbert M.

Haematologica. 2018 Aug 31. pii: haematol.2017.187278. doi: 10.3324/haematol.2017.187278. [Epub ahead of print]

2.

Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma.

Majumder S, Ghoshal K, Datta J, Bai S, Dong X, Quan N, Plass C, Jacob ST.

J Biol Chem. 2018 Aug 17;293(33):12948. doi: 10.1074/jbc.W118.004970. No abstract available.

3.

Introduction: Epigenetics in cancer.

Rosenquist R, Esteller M, Plass C.

Semin Cancer Biol. 2018 Aug;51:iv-v. doi: 10.1016/j.semcancer.2018.07.002. Epub 2018 Jul 7. No abstract available.

PMID:
29990621
4.

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.

Melnik S, Dvornikov D, Müller-Decker K, Depner S, Stannek P, Meister M, Warth A, Thomas M, Muley T, Risch A, Plass C, Klingmüller U, Niehrs C, Glinka A.

Cell Discov. 2018 Jul 3;4:37. doi: 10.1038/s41421-018-0033-2. eCollection 2018.

5.

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium.

Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, Jaeger S, Schlesner M, Aloy P, Eils R, Plass C, Augustin HG.

Elife. 2018 May 11;7. pii: e34423. doi: 10.7554/eLife.34423.

6.

Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors.

Daskalakis M, Brocks D, Sheng YH, Islam MS, Ressnerova A, Assenov Y, Milde T, Oehme I, Witt O, Goyal A, Kühn A, Hartmann M, Weichenhan D, Jung M, Plass C.

Cell Cycle. 2018;17(7):811-822. doi: 10.1080/15384101.2018.1442623. Epub 2018 Apr 30.

PMID:
29633898
7.

A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas.

Wirthschaft P, Bode J, Simon AEM, Hoffmann E, van Laack R, Krüwel T, Dietrich F, Bucher D, Hahn A, Sahm F, Breckwoldt MO, Kurz FT, Hielscher T, Fischer B, Dross N, Ruiz de Almodovar C, von Deimling A, Herold-Mende C, Plass C, Boulant S, Wiestler B, Reifenberger G, Lichter P, Wick W, Tews B.

Int J Cancer. 2018 Sep 1;143(5):1176-1187. doi: 10.1002/ijc.31404. Epub 2018 Apr 16.

PMID:
29582423
8.

Epigenetic deregulation in chronic lymphocytic leukemia: Clinical and biological impact.

Mansouri L, Wierzbinska JA, Plass C, Rosenquist R.

Semin Cancer Biol. 2018 Aug;51:1-11. doi: 10.1016/j.semcancer.2018.02.001. Epub 2018 Feb 7. Review.

PMID:
29427646
9.

Enrichment analysis with EpiAnnotator.

Pageaud Y, Plass C, Assenov Y.

Bioinformatics. 2018 May 15;34(10):1781-1783. doi: 10.1093/bioinformatics/bty007.

10.

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C.

Nat Commun. 2017 Dec 19;8(1):2126. doi: 10.1038/s41467-017-02177-w.

11.

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.

Stieglitz E, Mazor T, Olshen AB, Geng H, Gelston LC, Akutagawa J, Lipka DB, Plass C, Flotho C, Chehab FF, Braun BS, Costello JF, Loh ML.

Nat Commun. 2017 Dec 19;8(1):2127. doi: 10.1038/s41467-017-02178-9.

12.

Early-onset childhood atopic dermatitis is related to NLRP2 repression.

Thürmann L, Grützmann K, Klös M, Bieg M, Winter M, Polte T, Bauer T, Schick M, Bewerunge-Hudler M, Röder S, Bauer M, Wissenbach DK, Sack U, Weichenhan D, Mücke O, Plass C, Borte M, von Bergen M, Lehmann I, Eils R, Trump S.

J Allergy Clin Immunol. 2018 Apr;141(4):1482-1485.e16. doi: 10.1016/j.jaci.2017.11.018. Epub 2017 Dec 9. No abstract available.

13.

Drug-perturbation-based stratification of blood cancer.

Dietrich S, Oleś M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, Oleś AK, Słabicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T.

J Clin Invest. 2018 Jan 2;128(1):427-445. doi: 10.1172/JCI93801. Epub 2017 Dec 11.

14.

Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing.

Weichenhan D, Wang Q, Adey A, Wolf S, Shendure J, Eils R, Plass C.

Methods Mol Biol. 2018;1708:105-122. doi: 10.1007/978-1-4939-7481-8_6.

PMID:
29224141
15.

Melatonin attenuates thiocyanate-induced vasoconstriction in aortic rings.

Prusa AM, Plass CA.

Saudi Pharm J. 2017 Nov;25(7):993-998. doi: 10.1016/j.jsps.2017.03.007. Epub 2017 Mar 25.

16.

Corrigendum: Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Nov 16;18(12):1361. doi: 10.1038/ni1217-1361b.

PMID:
29144491
17.

Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability.

Jäkel C, Bergmann F, Toth R, Assenov Y, van der Duin D, Strobel O, Hank T, Klöppel G, Dorrell C, Grompe M, Moss J, Dor Y, Schirmacher P, Plass C, Popanda O, Schmezer P.

Nat Commun. 2017 Nov 6;8(1):1323. doi: 10.1038/s41467-017-01118-x.

18.

Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Oct 27;49(11):1661. doi: 10.1038/ng1117-1661c.

PMID:
29074949
19.

The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing.

Lim J, Park JH, Baude A, Yoo Y, Lee YK, Schmidt CR, Park JB, Fellenberg J, Zustin J, Haller F, Krücken I, Kang HG, Park YJ, Plass C, Lindroth AM.

Sci Rep. 2017 Oct 18;7(1):13459. doi: 10.1038/s41598-017-13887-y.

20.

Mitochondrial mutations drive prostate cancer aggression.

Hopkins JF, Sabelnykova VY, Weischenfeldt J, Simon R, Aguiar JA, Alkallas R, Heisler LE, Zhang J, Watson JD, Chua MLK, Fraser M, Favero F, Lawerenz C, Plass C, Sauter G, McPherson JD, van der Kwast T, Korbel J, Schlomm T, Bristow RG, Boutros PC.

Nat Commun. 2017 Sep 22;8(1):656. doi: 10.1038/s41467-017-00377-y.

21.

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib.

Wolf C, Garding A, Filarsky K, Bahlo J, Robrecht S, Becker N, Zucknick M, Rouhi A, Weigel A, Claus R, Weichenhan D, Eichhorst B, Fischer K, Hallek M, Kuchenbauer F, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Int J Cancer. 2018 Jan 15;142(2):322-333. doi: 10.1002/ijc.31057. Epub 2017 Oct 9.

PMID:
28921505
22.

BET-bromodomain inhibitors modulate epigenetic patterns at the diacylglycerol kinase alpha enhancer associated with radiation-induced fibrosis.

Valinciute G, Weigel C, Veldwijk MR, Oakes CC, Herskind C, Wenz F, Plass C, Schmezer P, Popanda O.

Radiother Oncol. 2017 Oct;125(1):168-174. doi: 10.1016/j.radonc.2017.08.028. Epub 2017 Sep 12.

PMID:
28916223
23.

Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.

Meder B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Frese K, Lai A, Nietsch R, Scheiner C, Mester S, Bordalo DM, Amr A, Dietrich C, Pils D, Siede D, Hund H, Bauer A, Holzer DB, Ruhparwar A, Mueller-Hennessen M, Weichenhan D, Plass C, Weis T, Backs J, Wuerstle M, Keller A, Katus HA, Posch AE.

Circulation. 2017 Oct 17;136(16):1528-1544. doi: 10.1161/CIRCULATIONAHA.117.027355. Epub 2017 Aug 24.

PMID:
28838933
24.

Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.

Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.

Nat Immunol. 2017 Oct;18(10):1160-1172. doi: 10.1038/ni.3799. Epub 2017 Aug 7. Erratum in: Nat Immunol. 2017 Nov 16;18(12 ):1361.

25.

Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer.

Heilmann K, Toth R, Bossmann C, Klimo K, Plass C, Gerhauser C.

Oncogene. 2017 Nov 16;36(46):6446-6461. doi: 10.1038/onc.2017.246. Epub 2017 Jul 31.

26.

Epigenetic dysregulation of the erythropoietic transcription factor KLF1 and the β-like globin locus in juvenile myelomonocytic leukemia.

Fluhr S, Krombholz CF, Meier A, Epting T, Mücke O, Plass C, Niemeyer CM, Flotho C.

Epigenetics. 2017 Aug;12(8):715-723. doi: 10.1080/15592294.2017.1356959. Epub 2017 Jul 27.

27.

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889. Epub 2017 Jun 12. Erratum in: Nat Genet. 2017 Oct 27;49(11):1661.

28.

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases.

Koelsche C, Schrimpf D, Tharun L, Roth E, Sturm D, Jones DTW, Renker EK, Sill M, Baude A, Sahm F, Capper D, Bewerunge-Hudler M, Hartmann W, Kulozik AE, Petersen I, Flucke U, Schreuder HWB, Büttner R, Weber MA, Schirmacher P, Plass C, Pfister SM, von Deimling A, Mechtersheimer G.

Clin Sarcoma Res. 2017 May 4;7:9. doi: 10.1186/s13569-017-0075-5. eCollection 2017.

29.

Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.

Jahreis S, Trump S, Bauer M, Bauer T, Thürmann L, Feltens R, Wang Q, Gu L, Grützmann K, Röder S, Averbeck M, Weichenhan D, Plass C, Sack U, Borte M, Dubourg V, Schüürmann G, Simon JC, von Bergen M, Hackermüller J, Eils R, Lehmann I, Polte T.

J Allergy Clin Immunol. 2018 Feb;141(2):741-753. doi: 10.1016/j.jaci.2017.03.017. Epub 2017 Apr 6.

30.

Melanoma-Derived iPCCs Show Differential Tumorigenicity and Therapy Response.

Bernhardt M, Novak D, Assenov Y, Orouji E, Knappe N, Weina K, Reith M, Larribere L, Gebhardt C, Plass C, Umansky V, Utikal J.

Stem Cell Reports. 2017 May 9;8(5):1379-1391. doi: 10.1016/j.stemcr.2017.03.007. Epub 2017 Apr 6.

31.

Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer.

Dewi DL, Mohapatra SR, Blanco Cabañes S, Adam I, Somarribas Patterson LF, Berdel B, Kahloon M, Thürmann L, Loth S, Heilmann K, Weichenhan D, Mücke O, Heiland I, Wimberger P, Kuhlmann JD, Kellner KH, Schott S, Plass C, Platten M, Gerhäuser C, Trump S, Opitz CA.

Oncoimmunology. 2017 Jan 3;6(2):e1274477. doi: 10.1080/2162402X.2016.1274477. eCollection 2017.

32.

TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation.

Yoo Y, Park JH, Weigel C, Liesenfeld DB, Weichenhan D, Plass C, Seo DG, Lindroth AM, Park YJ.

Int J Obes (Lond). 2017 Apr;41(4):652-659. doi: 10.1038/ijo.2017.8. Epub 2017 Feb 21.

PMID:
28100914
33.

Stability of the human sperm DNA methylome to folic acid fortification and short-term supplementation.

Chan D, McGraw S, Klein K, Wallock LM, Konermann C, Plass C, Chan P, Robaire B, Jacob RA, Greenwood CM, Trasler JM.

Hum Reprod. 2017 Feb;32(2):272-283. doi: 10.1093/humrep/dew308. Epub 2016 Dec 18.

34.

IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus.

Drennan S, D'Avola A, Gao Y, Weigel C, Chrysostomou E, Steele AJ, Zenz T, Plass C, Johnson PW, Williams AP, Packham G, Stevenson FK, Oakes CC, Forconi F.

Leukemia. 2017 Aug;31(8):1686-1694. doi: 10.1038/leu.2016.356. Epub 2016 Nov 28.

PMID:
27890932
35.

Prognostic relevance of miRNA-155 methylation in anaplastic glioma.

Schliesser MG, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, Wiestler B, Hau P, Schramm J, Sahm F, Weiß EK, Weiler M, Baer C, Schmidt-Graf F, Schackert G, Westphal M, Hertenstein A, Roth P, Galldiks N, Hartmann C, Pietsch T, Felsberg J, Reifenberger G, Sabel MC, Winkler F, von Deimling A, Meisner C, Vajkoczy P, Platten M, Weller M, Plass C, Wick W.

Oncotarget. 2016 Dec 13;7(50):82028-82045. doi: 10.18632/oncotarget.13452.

36.

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma.

Goeppert B, Ernst C, Baer C, Roessler S, Renner M, Mehrabi A, Hafezi M, Pathil A, Warth A, Stenzinger A, Weichert W, Bähr M, Will R, Schirmacher P, Plass C, Weichenhan D.

Epigenetics. 2016 Nov;11(11):780-790. Epub 2016 Sep 3.

37.

150 years of Johann Gregor Mendel's "Versuche über Pflanzen-Hybriden".

Hoßfeld U, Jacobsen HJ, Plass C, Brors B, Wackernagel W.

Mol Genet Genomics. 2017 Feb;292(1):1-3. doi: 10.1007/s00438-016-1254-4. Epub 2016 Oct 11. No abstract available.

PMID:
27730306
38.

Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas.

Henrich KO, Bender S, Saadati M, Dreidax D, Gartlgruber M, Shao C, Herrmann C, Wiesenfarth M, Parzonka M, Wehrmann L, Fischer M, Duffy DJ, Bell E, Torkov A, Schmezer P, Plass C, Höfer T, Benner A, Pfister SM, Westermann F.

Cancer Res. 2016 Sep 15;76(18):5523-37. doi: 10.1158/0008-5472.CAN-15-2507. Epub 2016 Sep 7.

39.

Assessment of Promoter Methylation Identifies PTCH as a Putative Tumor-suppressor Gene in Human CLL.

Schmidt-Wolf IG, Plass C, Byrd JC, Frevel K, Pietsch T, Waha A.

Anticancer Res. 2016 Sep;36(9):4515-9.

PMID:
27630290
40.

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.

Moran S, Martínez-Cardús A, Sayols S, Musulén E, Balañá C, Estival-Gonzalez A, Moutinho C, Heyn H, Diaz-Lagares A, de Moura MC, Stella GM, Comoglio PM, Ruiz-Miró M, Matias-Guiu X, Pazo-Cid R, Antón A, Lopez-Lopez R, Soler G, Longo F, Guerra I, Fernandez S, Assenov Y, Plass C, Morales R, Carles J, Bowtell D, Mileshkin L, Sia D, Tothill R, Tabernero J, Llovet JM, Esteller M.

Lancet Oncol. 2016 Oct;17(10):1386-1395. doi: 10.1016/S1470-2045(16)30297-2. Epub 2016 Aug 27.

PMID:
27575023
41.

Dissection of CD20 regulation in lymphoma using RNAi.

Słabicki M, Lee KS, Jethwa A, Sellner L, Sacco F, Walther T, Hüllein J, Dietrich S, Wu B, Lipka DB, Oakes CC, Mamidi S, Pyrzyńska B, Winiarska M, Oleś M, Seifert M, Plass C, Kirschfink M, Boettcher M, Gołąb J, Huber W, Fröhling S, Zenz T.

Leukemia. 2016 Dec;30(12):2409-2412. doi: 10.1038/leu.2016.230. Epub 2016 Aug 18. No abstract available.

PMID:
27560109
42.

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.

Merkle R, Steiert B, Salopiata F, Depner S, Raue A, Iwamoto N, Schelker M, Hass H, Wäsch M, Böhm ME, Mücke O, Lipka DB, Plass C, Lehmann WD, Kreutz C, Timmer J, Schilling M, Klingmüller U.

PLoS Comput Biol. 2016 Aug 5;12(8):e1005049. doi: 10.1371/journal.pcbi.1005049. eCollection 2016 Aug.

43.

Coating of intravascular balloon with paclitaxel prevents constrictive remodeling of the dilated porcine femoral artery due to inhibition of intimal and media fibrosis.

Pavo N, Samaha E, Sabdyusheva I, von Strandmann RP, Stahnke S, Plass CA, Zlabinger K, Lukovic D, Jambrik Z, Pavo IJ, Bergler-Klein J, Gray WA, Maurer G, Gyöngyösi M.

J Mater Sci Mater Med. 2016 Aug;27(8):131. doi: 10.1007/s10856-016-5737-y. Epub 2016 Jul 7.

44.

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation.

Trump S, Bieg M, Gu Z, Thürmann L, Bauer T, Bauer M, Ishaque N, Röder S, Gu L, Herberth G, Lawerenz C, Borte M, Schlesner M, Plass C, Diessl N, Eszlinger M, Mücke O, Elvers HD, Wissenbach DK, von Bergen M, Herrmann C, Weichenhan D, Wright RJ, Lehmann I, Eils R.

Sci Rep. 2016 Jun 28;6:28616. doi: 10.1038/srep28616.

45.

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL.

D'Avola A, Drennan S, Tracy I, Henderson I, Chiecchio L, Larrayoz M, Rose-Zerilli M, Strefford J, Plass C, Johnson PW, Steele AJ, Packham G, Stevenson FK, Oakes CC, Forconi F.

Blood. 2016 Aug 11;128(6):816-26. doi: 10.1182/blood-2016-03-707786. Epub 2016 Jun 14.

46.

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.

Fluhr S, Boerries M, Busch H, Symeonidi A, Witte T, Lipka DB, Mücke O, Nöllke P, Krombholz CF, Niemeyer CM, Plass C, Flotho C.

Clin Epigenetics. 2016 May 5;8:50. doi: 10.1186/s13148-016-0216-3. eCollection 2016.

47.

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia.

Chen TL, Gupta N, Lehman A, Ruppert AS, Yu L, Oakes CC, Claus R, Plass C, Maddocks KJ, Andritsos L, Jones JA, Lucas DM, Johnson AJ, Byrd JC, Hertlein E.

Oncotarget. 2016 May 10;7(19):28684-96. doi: 10.18632/oncotarget.8760.

48.

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling.

Filarsky K, Garding A, Becker N, Wolf C, Zucknick M, Claus R, Weichenhan D, Plass C, Döhner H, Stilgenbauer S, Lichter P, Mertens D.

Haematologica. 2016 Jun;101(6):e249-53. doi: 10.3324/haematol.2015.138172. Epub 2016 Apr 14. No abstract available.

49.

Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children.

Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R, Lehmann I.

Mol Syst Biol. 2016 Mar 24;12(3):861. doi: 10.15252/msb.20156520.

50.

Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis.

Weigel C, Veldwijk MR, Oakes CC, Seibold P, Slynko A, Liesenfeld DB, Rabionet M, Hanke SA, Wenz F, Sperk E, Benner A, Rösli C, Sandhoff R, Assenov Y, Plass C, Herskind C, Chang-Claude J, Schmezer P, Popanda O.

Nat Commun. 2016 Mar 11;7:10893. doi: 10.1038/ncomms10893.

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