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Items: 1 to 50 of 194

1.

Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke.

Salas-Perdomo A, Miró-Mur F, Gallizioli M, Brait VH, Justicia C, Meissner A, Urra X, Chamorro A, Planas AM.

Sci Rep. 2019 Jun 5;9(1):8309. doi: 10.1038/s41598-019-44845-5.

2.

Location of Neutrophils in Different Compartments of the Damaged Mouse Brain After Severe Ischemia/Reperfusion.

Otxoa-de-Amezaga A, Gallizioli M, Pedragosa J, Justicia C, Miró-Mur F, Salas-Perdomo A, Díaz-Marugan L, Gunzer M, Planas AM.

Stroke. 2019 Jun;50(6):1548-1557. doi: 10.1161/STROKEAHA.118.023837. Epub 2019 May 14.

PMID:
31084324
3.

Uric acid treatment after stroke modulates the Krüppel-like factor 2-VEGF-A axis to protect brain endothelial cell functions: Impact of hypertension.

Vila E, Solé M, Masip N, Puertas-Umbert L, Amaro S, Dantas AP, Unzeta M, D'Ocon P, Planas AM, Chamorro Á, Jiménez-Altayó F.

Biochem Pharmacol. 2019 Jun;164:115-128. doi: 10.1016/j.bcp.2019.04.002. Epub 2019 Apr 4.

PMID:
30954486
4.

CD69 Plays a Beneficial Role in Ischemic Stroke by Dampening Endothelial Activation.

Brait VH, Miró-Mur F, Pérez-de-Puig I, Notario L, Hurtado B, Pedragosa J, Gallizioli M, Jiménez-Altayó F, Arbaizar-Rovirosa M, Otxoa-de-Amezaga A, Monteagudo J, Ferrer-Ferrer M, de la Rosa X, Bonfill-Teixidor E, Salas-Perdomo A, Hernández-Vidal A, Garcia-de-Frutos P, Lauzurica P, Planas AM.

Circ Res. 2019 Jan 18;124(2):279-291. doi: 10.1161/CIRCRESAHA.118.313818.

PMID:
30582456
5.

Microglial cell loss after ischemic stroke favors brain neutrophil accumulation.

Otxoa-de-Amezaga A, Miró-Mur F, Pedragosa J, Gallizioli M, Justicia C, Gaja-Capdevila N, Ruíz-Jaen F, Salas-Perdomo A, Bosch A, Calvo M, Márquez-Kisinousky L, Denes A, Gunzer M, Planas AM.

Acta Neuropathol. 2019 Feb;137(2):321-341. doi: 10.1007/s00401-018-1954-4. Epub 2018 Dec 22.

6.

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD.

Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018.

7.

Role of Immune Cells Migrating to the Ischemic Brain.

Planas AM.

Stroke. 2018 Sep;49(9):2261-2267. doi: 10.1161/STROKEAHA.118.021474. No abstract available.

PMID:
30355002
8.

Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats.

Jiménez-Xarrié E, Pérez B, Dantas AP, Puertas-Umbert L, Martí-Fabregas J, Chamorro Á, Planas AM, Vila E, Jiménez-Altayó F.

Transl Stroke Res. 2018 Sep 15. doi: 10.1007/s12975-018-0661-8. [Epub ahead of print]

PMID:
30219993
9.

CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage.

Pedragosa J, Salas-Perdomo A, Gallizioli M, Cugota R, Miró-Mur F, Briansó F, Justicia C, Pérez-Asensio F, Marquez-Kisinousky L, Urra X, Gieryng A, Kaminska B, Chamorro A, Planas AM.

Acta Neuropathol Commun. 2018 Aug 9;6(1):76. doi: 10.1186/s40478-018-0581-6.

10.

T Cells Prevent Hemorrhagic Transformation in Ischemic Stroke by P-Selectin Binding.

Salas-Perdomo A, Miró-Mur F, Urra X, Justicia C, Gallizioli M, Zhao Y, Brait VH, Laredo C, Tudela R, Hidalgo A, Chamorro Á, Planas AM.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1761-1771. doi: 10.1161/ATVBAHA.118.311284.

PMID:
29903733
11.

Advances in Stroke 2017.

Bernhardt J, Zorowitz RD, Becker KJ, Keller E, Saposnik G, Strbian D, Dichgans M, Woo D, Reeves M, Thrift A, Kidwell CS, Olivot JM, Goyal M, Pierot L, Bennett DA, Howard G, Ford GA, Goldstein LB, Planas AM, Yenari MA, Greenberg SM, Pantoni L, Amin-Hanjani S, Tymianski M.

Stroke. 2018 May;49(5):e174-e199. doi: 10.1161/STROKEAHA.118.021380. Epub 2018 Apr 18. Review. No abstract available.

PMID:
29669874
12.

Adrenal hormones and circulating leukocyte subtypes in stroke patients treated with reperfusion therapy.

Miró-Mur F, Laredo C, Renú A, Rudilosso S, Zhao Y, Amaro S, Llull L, Urra X, Planas AM, Chamorro Á.

Brain Behav Immun. 2018 May;70:346-353. doi: 10.1016/j.bbi.2018.03.018. Epub 2018 Mar 13.

PMID:
29548995
13.

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.

Gelderblom M, Gallizioli M, Ludewig P, Thom V, Arunachalam P, Rissiek B, Bernreuther C, Glatzel M, Korn T, Arumugam TV, Sedlacik J, Gerloff C, Tolosa E, Planas AM, Magnus T.

Stroke. 2018 Jan;49(1):155-164. doi: 10.1161/STROKEAHA.117.019101. Epub 2017 Dec 6.

PMID:
29212740
14.

Complete reperfusion is required for maximal benefits of mechanical thrombectomy in stroke patients.

Chamorro Á, Blasco J, López A, Amaro S, Román LS, Llull L, Renú A, Rudilosso S, Laredo C, Obach V, Urra X, Planas AM, Leira EC, Macho J.

Sci Rep. 2017 Sep 14;7(1):11636. doi: 10.1038/s41598-017-11946-y.

15.

Intraarterial route increases the risk of cerebral lesions after mesenchymal cell administration in animal model of ischemia.

Argibay B, Trekker J, Himmelreich U, Beiras A, Topete A, Taboada P, Pérez-Mato M, Vieites-Prado A, Iglesias-Rey R, Rivas J, Planas AM, Sobrino T, Castillo J, Campos F.

Sci Rep. 2017 Jan 16;7:40758. doi: 10.1038/srep40758.

16.

Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide.

Bonfill-Teixidor E, Otxoa-de-Amezaga A, Font-Nieves M, Sans-Fons MG, Planas AM.

J Neuroinflammation. 2017 Jan 5;14(1):3. doi: 10.1186/s12974-016-0780-7.

17.

Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension.

Meissner A, Miro F, Jiménez-Altayó F, Jurado A, Vila E, Planas AM.

Cardiovasc Res. 2017 Feb;113(2):123-133. doi: 10.1093/cvr/cvw256. Epub 2017 Jan 12.

PMID:
28082452
18.

Uric Acid Is Protective After Cerebral Ischemia/Reperfusion in Hyperglycemic Mice.

Justicia C, Salas-Perdomo A, Pérez-de-Puig I, Deddens LH, van Tilborg GAF, Castellví C, Dijkhuizen RM, Chamorro Á, Planas AM.

Transl Stroke Res. 2017 Jun;8(3):294-305. doi: 10.1007/s12975-016-0515-1. Epub 2016 Dec 15.

PMID:
27981484
19.

Structural and functional brain alterations in a murine model of Angiotensin II-induced hypertension.

Meissner A, Minnerup J, Soria G, Planas AM.

J Neurochem. 2017 Feb;140(3):509-521. doi: 10.1111/jnc.13905. Epub 2016 Dec 21.

20.

Selective Sphingosine 1-Phosphate Receptor 1 Agonist Is Protective Against Ischemia/Reperfusion in Mice.

Brait VH, Tarrasón G, Gavaldà A, Godessart N, Planas AM.

Stroke. 2016 Dec;47(12):3053-3056. Epub 2016 Nov 8.

PMID:
27827329
21.

Uric Acid Therapy Prevents Early Ischemic Stroke Progression: A Tertiary Analysis of the URICO-ICTUS Trial (Efficacy Study of Combined Treatment With Uric Acid and r-tPA in Acute Ischemic Stroke).

Amaro S, Laredo C, Renú A, Llull L, Rudilosso S, Obach V, Urra X, Planas AM, Chamorro Á; URICO-ICTUS Investigators.

Stroke. 2016 Nov;47(11):2874-2876. Epub 2016 Oct 6.

PMID:
27758945
22.

Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.

Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P.

Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29.

PMID:
27685637
23.

Antigen Presentation After Stroke.

Miró-Mur F, Urra X, Gallizioli M, Chamorro A, Planas AM.

Neurotherapeutics. 2016 Oct;13(4):719-728. doi: 10.1007/s13311-016-0469-8. Review.

24.

Neuroanatomical correlates of stroke-associated infection and stroke-induced immunodepression.

Urra X, Laredo C, Zhao Y, Amaro S, Rudilosso S, Renú A, Prats-Galino A, Planas AM, Oleaga L, Chamorro Á.

Brain Behav Immun. 2017 Feb;60:142-150. doi: 10.1016/j.bbi.2016.10.004. Epub 2016 Oct 11.

PMID:
27742582
25.

Ficolin-1 Levels in Patients Developing Vasospasm and Cerebral Ischemia After Spontaneous Subarachnoid Hemorrhage.

Llull L, Thiel S, Amaro S, Cervera Á, Planas AM, Chamorro Á.

Mol Neurobiol. 2017 Oct;54(8):6572-6580. doi: 10.1007/s12035-016-0180-0. Epub 2016 Oct 12.

PMID:
27734336
26.

Third European Stroke Science Workshop.

Dichgans M, Planas AM, Biessels GJ, van der Worp B, Sudlow C, Norrving B, Lees K, Mattle HP.

Stroke. 2016 Jul;47(7):e178-86. doi: 10.1161/STROKEAHA.116.013516. Epub 2016 Jun 9.

PMID:
27283200
27.

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation.

Chamorro Á, Dirnagl U, Urra X, Planas AM.

Lancet Neurol. 2016 Jul;15(8):869-881. doi: 10.1016/S1474-4422(16)00114-9. Epub 2016 May 11. Review.

PMID:
27180033
28.

Uric acid therapy improves the outcomes of stroke patients treated with intravenous tissue plasminogen activator and mechanical thrombectomy.

Chamorro Á, Amaro S, Castellanos M, Gomis M, Urra X, Blasco J, Arenillas JF, Román LS, Muñoz R, Macho J, Cánovas D, Marti-Fabregas J, Leira EC, Planas AM; URICO-ICTUS Investigators.

Int J Stroke. 2017 Jun;12(4):377-382. doi: 10.1177/1747493016684354. Epub 2016 Dec 20.

PMID:
28345429
29.

Dendritic cells in brain diseases.

Ludewig P, Gallizioli M, Urra X, Behr S, Brait VH, Gelderblom M, Magnus T, Planas AM.

Biochim Biophys Acta. 2016 Mar;1862(3):352-67. doi: 10.1016/j.bbadis.2015.11.003. Epub 2015 Nov 10. Review. No abstract available.

30.

Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation.

Miró-Mur F, Pérez-de-Puig I, Ferrer-Ferrer M, Urra X, Justicia C, Chamorro A, Planas AM.

Brain Behav Immun. 2016 Mar;53:18-33. doi: 10.1016/j.bbi.2015.08.010. Epub 2015 Aug 12.

PMID:
26275369
31.

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia.

Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, Dirnagl U, Grittner U, Planas AM, Plesnila N, Vivien D, Liesz A.

Sci Transl Med. 2015 Aug 5;7(299):299ra121. doi: 10.1126/scitranslmed.aaa9853.

PMID:
26246166
32.

Immunomodulatory role of IL-33 counteracts brain inflammation in stroke.

Planas AM.

Brain Behav Immun. 2015 Nov;50:39-40. doi: 10.1016/j.bbi.2015.07.027. Epub 2015 Jul 30. No abstract available.

PMID:
26234503
33.

IFN gamma regulates proliferation and neuronal differentiation by STAT1 in adult SVZ niche.

Pereira L, Medina R, Baena M, Planas AM, Pozas E.

Front Cell Neurosci. 2015 Jul 13;9:270. doi: 10.3389/fncel.2015.00270. eCollection 2015.

34.

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke.

Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz HJ, Faust A, Hermann S, Kopka K, Faber C, Dollé F, Pappata S, Planas AM, Tavitian B, Schäfers M, Sorokin LM, Kuhlmann MT, Jacobs AH.

J Cereb Blood Flow Metab. 2015 Nov;35(11):1711-21. doi: 10.1038/jcbfm.2015.149. Epub 2015 Jul 1.

35.

IL-10 regulates adult neurogenesis by modulating ERK and STAT3 activity.

Pereira L, Font-Nieves M, Van den Haute C, Baekelandt V, Planas AM, Pozas E.

Front Cell Neurosci. 2015 Feb 25;9:57. doi: 10.3389/fncel.2015.00057. eCollection 2015.

36.

Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: a target of uric acid treatment.

Onetti Y, Dantas AP, Pérez B, Cugota R, Chamorro A, Planas AM, Vila E, Jiménez-Altayó F.

Am J Physiol Heart Circ Physiol. 2015 Apr 15;308(8):H862-74. doi: 10.1152/ajpheart.00001.2015. Epub 2015 Jan 30.

37.

Uric acid improves glucose-driven oxidative stress in human ischemic stroke.

Amaro S, Llull L, Renú A, Laredo C, Perez B, Vila E, Torres F, Planas AM, Chamorro Á.

Ann Neurol. 2015 May;77(5):775-83. doi: 10.1002/ana.24378. Epub 2015 Mar 13.

PMID:
25627874
38.

Neutrophil recruitment to the brain in mouse and human ischemic stroke.

Perez-de-Puig I, Miró-Mur F, Ferrer-Ferrer M, Gelpi E, Pedragosa J, Justicia C, Urra X, Chamorro A, Planas AM.

Acta Neuropathol. 2015 Feb;129(2):239-57. doi: 10.1007/s00401-014-1381-0. Epub 2014 Dec 30.

PMID:
25548073
39.

Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death.

Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Tajes M, Valls-Comamala V, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Gil-Gómez G, Lopez-Vilchez I, Galan AM, Alameda F, Escolar G, Opazo C, Planas AM, Roquer J, Valverde MA, Muñoz FJ.

Biochim Biophys Acta. 2015 Mar;1852(3):421-8. doi: 10.1016/j.bbadis.2014.12.007. Epub 2014 Dec 12.

40.

Antigen-specific immune reactions to ischemic stroke.

Urra X, Miró F, Chamorro A, Planas AM.

Front Cell Neurosci. 2014 Sep 12;8:278. doi: 10.3389/fncel.2014.00278. eCollection 2014. Review.

41.

Infarct volume prediction using apparent diffusion coefficient maps during middle cerebral artery occlusion and soon after reperfusion in the rat.

Tudela R, Soria G, Pérez-De-Puig I, Ros D, Pavía J, Planas AM.

Brain Res. 2014 Oct 2;1583:169-78. doi: 10.1016/j.brainres.2014.08.008. Epub 2014 Aug 14.

PMID:
25128601
42.

DWI and complex brain network analysis predicts vascular cognitive impairment in spontaneous hypertensive rats undergoing executive function tests.

López-Gil X, Amat-Roldan I, Tudela R, Castañé A, Prats-Galino A, Planas AM, Farr TD, Soria G.

Front Aging Neurosci. 2014 Jul 23;6:167. doi: 10.3389/fnagi.2014.00167. eCollection 2014.

43.

Brain tissue hypoxia and oxidative stress induced by obstructive apneas is different in young and aged rats.

Dalmases M, Torres M, Márquez-Kisinousky L, Almendros I, Planas AM, Embid C, Martínez-Garcia MÁ, Navajas D, Farré R, Montserrat JM.

Sleep. 2014 Jul 1;37(7):1249-56. doi: 10.5665/sleep.3848.

44.

Urate and neuroprotection trials--authors' reply.

Chamorro Á, Amaro S, Planas AM.

Lancet Neurol. 2014 Aug;13(8):758-9. doi: 10.1016/S1474-4422(14)70139-5. No abstract available.

PMID:
25030509
45.

Letter to the editor: "Targeting cerebrovascular myogenic dysfunction in stroke".

Jiménez-Altayó F, Planas AM, Vila E.

Am J Physiol Heart Circ Physiol. 2014 May 15;306(10):H1481-2. doi: 10.1152/ajpheart.00178.2014. No abstract available.

46.

Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial.

Chamorro A, Amaro S, Castellanos M, Segura T, Arenillas J, Martí-Fábregas J, Gállego J, Krupinski J, Gomis M, Cánovas D, Carné X, Deulofeu R, Román LS, Oleaga L, Torres F, Planas AM; URICO-ICTUS Investigators.

Lancet Neurol. 2014 May;13(5):453-60. doi: 10.1016/S1474-4422(14)70054-7. Epub 2014 Apr 2.

PMID:
24703208
47.

Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice.

de la Rosa X, Cervera A, Kristoffersen AK, Valdés CP, Varma HM, Justicia C, Durduran T, Chamorro Á, Planas AM.

Stroke. 2014 May;45(5):1453-9. doi: 10.1161/STROKEAHA.113.004111. Epub 2014 Mar 27.

PMID:
24676774
48.

Presence of heat shock protein 70 in secondary lymphoid tissue correlates with stroke prognosis.

Gómez-Choco M, Doucerain C, Urra X, Planas AM, Chamorro A.

J Neuroimmunol. 2014 May 15;270(1-2):67-74. doi: 10.1016/j.jneuroim.2014.03.004. Epub 2014 Mar 12.

PMID:
24656941
49.

Dual-reporter in vivo imaging of transient and inducible heat-shock promoter activation.

Fortin PY, Genevois C, Chapolard M, Santalucía T, Planas AM, Couillaud F.

Biomed Opt Express. 2014 Jan 13;5(2):457-67. doi: 10.1364/BOE.5.000457. eCollection 2014 Feb 1.

50.

SIRT1 regulation modulates stroke outcome.

Petegnief V, Planas AM.

Transl Stroke Res. 2013 Dec;4(6):663-71. doi: 10.1007/s12975-013-0277-y. Epub 2013 Aug 15. Review.

PMID:
24323420

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