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Items: 1 to 50 of 134

1.

Sex-specific epigenetic alterations of the hypothalamic Agrp-Pomc system do not explain 'diabesity' in the offspring of high-fat diet (HFD) overfed maternal rats.

Schellong K, Melchior K, Ziska T, Henrich W, Rancourt RC, Plagemann A.

J Nutr Biochem. 2019 Oct 23;75:108257. doi: 10.1016/j.jnutbio.2019.108257. [Epub ahead of print]

PMID:
31710935
2.

Visceral adipose tissue alteration of PI3KR1 expression is associated with gestational diabetes but not promoter DNA methylation.

Rancourt RC, Ott R, Schellong K, Melchior K, Ziska T, Henrich W, Plagemann A.

Adipocyte. 2019 Dec;8(1):339-346. doi: 10.1080/21623945.2019.1675239.

PMID:
31608772
3.

Hypothalamic insulin receptor expression and DNA promoter methylation are sex-specifically altered in adult offspring of high-fat diet (HFD)-overfed mother rats.

Schellong K, Melchior K, Ziska T, Ott R, Henrich W, Rancourt RC, Plagemann A.

J Nutr Biochem. 2019 May;67:28-35. doi: 10.1016/j.jnutbio.2019.01.014. Epub 2019 Feb 10.

PMID:
30849557
4.

Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome.

Ott R, Stupin JH, Melchior K, Schellong K, Ziska T, Dudenhausen JW, Henrich W, Rancourt RC, Plagemann A.

Clin Epigenetics. 2018 Oct 24;10(1):131. doi: 10.1186/s13148-018-0567-z.

5.

Reduced Insulin Receptor Expression and Altered DNA Methylation in Fat Tissues and Blood of Women With GDM and Offspring.

Ott R, Melchior K, Stupin JH, Ziska T, Schellong K, Henrich W, Rancourt RC, Plagemann A.

J Clin Endocrinol Metab. 2019 Jan 1;104(1):137-149. doi: 10.1210/jc.2018-01659.

PMID:
30260402
6.

Sex-specific and lasting effects of a single course of antenatal betamethasone treatment on human placental 11β-HSD2.

Braun F, Hardt AK, Ehrlich L, Sloboda DM, Challis JRG, Plagemann A, Henrich W, Braun T.

Placenta. 2018 Sep;69:9-19. doi: 10.1016/j.placenta.2018.07.007. Epub 2018 Jul 11.

PMID:
30213491
7.

DNA methylation and expression of proopiomelanocortin (POMC) gene in the hypothalamus of three-week-old chickens show sex-specific differences.

Rancourt RC, Schellong K, Tzschentke B, Henrich W, Plagemann A.

FEBS Open Bio. 2018 Apr 27;8(6):932-939. doi: 10.1002/2211-5463.12427. eCollection 2018 Jun.

8.

Maternal overweight is not an independent risk factor for increased birth weight, leptin and insulin in newborns of gestational diabetic women: observations from the prospective 'EaCH' cohort study.

Ott R, Stupin JH, Loui A, Eilers E, Melchior K, Rancourt RC, Schellong K, Ziska T, Dudenhausen JW, Henrich W, Plagemann A.

BMC Pregnancy Childbirth. 2018 Jun 20;18(1):250. doi: 10.1186/s12884-018-1889-8.

9.

The importance of selecting the right internal control gene to study the effects of antenatal glucocorticoid administration in human placenta.

Gütling H, Bionaz M, Sloboda DM, Ehrlich L, Braun F, Gramzow AK, Henrich W, Plagemann A, Braun T.

Placenta. 2016 Aug;44:19-22. doi: 10.1016/j.placenta.2016.05.011. Epub 2016 May 27.

PMID:
27452434
10.

Fetal and neonatal outcomes after term and preterm delivery following betamethasone administration in twin pregnancies.

Braun T, Weichert A, Gil HC, Sloboda DM, Tutschek B, Harder T, Dudenhausen JW, Plagemann A, Henrich W.

Int J Gynaecol Obstet. 2016 Sep;134(3):329-35. doi: 10.1016/j.ijgo.2016.02.016. Epub 2016 May 24.

PMID:
27365289
11.

Temporary prenatal hyperglycemia leads to postnatal neuronal 'glucose-resistance' in the chicken hypothalamus.

Tzschentke B, Bogatyrev S, Schellong K, Rancourt RC, Plagemann A.

Brain Res. 2015 Aug 27;1618:231-40. doi: 10.1016/j.brainres.2015.05.037. Epub 2015 Jun 6.

PMID:
26054304
12.

The dilution effect and the importance of selecting the right internal control genes for RT-qPCR: a paradigmatic approach in fetal sheep.

Xu H, Bionaz M, Sloboda DM, Ehrlich L, Li S, Newnham JP, Dudenhausen JW, Henrich W, Plagemann A, Challis JR, Braun T.

BMC Res Notes. 2015 Feb 27;8:58. doi: 10.1186/s13104-015-0973-7.

13.

Fetal and neonatal outcomes after term and preterm delivery following betamethasone administration.

Braun T, Sloboda DM, Tutschek B, Harder T, Challis JR, Dudenhausen JW, Plagemann A, Henrich W.

Int J Gynaecol Obstet. 2015 Jul;130(1):64-9. doi: 10.1016/j.ijgo.2015.01.013. Epub 2015 Mar 31.

PMID:
25872453
14.

Acquired alterations of hypothalamic gene expression of insulin and leptin receptors and glucose transporters in prenatally high-glucose exposed three-week old chickens do not coincide with aberrant promoter DNA methylation.

Rancourt RC, Schellong K, Ott R, Bogatyrev S, Tzschentke B, Plagemann A.

PLoS One. 2015 Mar 26;10(3):e0119213. doi: 10.1371/journal.pone.0119213. eCollection 2015.

15.

Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?

Justus G, Sloboda DM, Henrich W, Plagemann A, Dudenhausen JW, Braun T.

J Perinat Med. 2015 Sep;43(5):503-23. doi: 10.1515/jpm-2014-0295. Review.

PMID:
25405717
16.

Effects of maternal dexamethasone treatment early in pregnancy on glucocorticoid receptors in the ovine placenta.

Shang H, Meng W, Sloboda DM, Li S, Ehrlich L, Plagemann A, Dudenhausen JW, Henrich W, Newnham JP, Challis JR, Braun T.

Reprod Sci. 2015 May;22(5):534-44. doi: 10.1177/1933719114553452. Epub 2014 Oct 20.

17.

Detection of long-term influence of prenatal temperature stimulation on hypothalamic type-II iodothyronine deiodinase in juvenile female broiler chickens using a novel immunohistochemical amplification protocol.

Nassar M, Halle I, Plagemann A, Tzschentke B.

Comp Biochem Physiol A Mol Integr Physiol. 2015 Jan;179:120-4. doi: 10.1016/j.cbpa.2014.09.038. Epub 2014 Oct 5.

PMID:
25289994
18.

Early dexamethasone treatment induces placental apoptosis in sheep.

Braun T, Meng W, Shang H, Li S, Sloboda DM, Ehrlich L, Lange K, Xu H, Henrich W, Dudenhausen JW, Plagemann A, Newnham JP, Challis JR.

Reprod Sci. 2015 Jan;22(1):47-59. doi: 10.1177/1933719114542028. Epub 2014 Jul 25.

19.

Increase of long-term 'diabesity' risk, hyperphagia, and altered hypothalamic neuropeptide expression in neonatally overnourished 'small-for-gestational-age' (SGA) rats.

Schellong K, Neumann U, Rancourt RC, Plagemann A.

PLoS One. 2013 Nov 12;8(11):e78799. doi: 10.1371/journal.pone.0078799. eCollection 2013.

20.

Growth restricting effects of a single course of antenatal betamethasone treatment and the role of human placental lactogen.

Braun T, Husar A, Challis JR, Dudenhausen JW, Henrich W, Plagemann A, Sloboda DM.

Placenta. 2013 May;34(5):407-15. doi: 10.1016/j.placenta.2013.02.002. Epub 2013 Mar 5.

PMID:
23465880
21.

Rapid neonatal weight gain increases risk of childhood overweight in offspring of diabetic mothers.

Plagemann A, Harder T, Rodekamp E, Kohlhoff R.

J Perinat Med. 2012 Sep;40(5):557-63. doi: 10.1515/jpm-2011-0270.

PMID:
23104799
22.

Birth weight and long-term overweight risk: systematic review and a meta-analysis including 643,902 persons from 66 studies and 26 countries globally.

Schellong K, Schulz S, Harder T, Plagemann A.

PLoS One. 2012;7(10):e47776. doi: 10.1371/journal.pone.0047776. Epub 2012 Oct 17. Review.

23.

Early postnatal life as a critical time window for determination of long-term metabolic health.

Plagemann A, Harder T, Schellong K, Schulz S, Stupin JH.

Best Pract Res Clin Endocrinol Metab. 2012 Oct;26(5):641-53. doi: 10.1016/j.beem.2012.03.008. Epub 2012 May 22.

PMID:
22980046
24.

Short-term regulation of the hypothalamic melanocortinergic system under fasting and defined glucose-refeeding conditions in rats: a laser capture microdissection (LMD)-based study.

Landmann EM, Schellong K, Melchior K, Rodekamp E, Ziska T, Harder T, Plagemann A.

Neurosci Lett. 2012 Apr 25;515(1):87-91. doi: 10.1016/j.neulet.2012.03.025. Epub 2012 Mar 20.

PMID:
22450045
25.

Maternal diabetes and perinatal programming.

Plagemann A.

Early Hum Dev. 2011 Nov;87(11):743-7. doi: 10.1016/j.earlhumdev.2011.08.018. Epub 2011 Sep 23.

PMID:
21945359
26.

[Perinatal nutrition and hypertension].

Harder T, Plagemann A.

Klin Padiatr. 2011 Mar;223 Suppl 1:S1-9. doi: 10.1055/s-0030-1255689. Epub 2011 Apr 6. Review. German. No abstract available.

PMID:
21472671
27.

Leptin determination in colostrum and early human milk from mothers of preterm and term infants.

Eilers E, Ziska T, Harder T, Plagemann A, Obladen M, Loui A.

Early Hum Dev. 2011 Jun;87(6):415-9. doi: 10.1016/j.earlhumdev.2011.03.004. Epub 2011 Apr 11.

PMID:
21482454
28.

Intrauterine growth restriction and developmental programming of the metabolic syndrome: a critical appraisal.

Neitzke U, Harder T, Plagemann A.

Microcirculation. 2011 May;18(4):304-11. doi: 10.1111/j.1549-8719.2011.00089.x. Review.

PMID:
21418379
29.

Fuel-mediated teratogenesis and breastfeeding.

Plagemann A, Harder T.

Diabetes Care. 2011 Mar;34(3):779-81. doi: 10.2337/dc10-2369. No abstract available.

30.

Childhood obesity, other cardiovascular risk factors, and premature death.

Plagemann A, Harder T, Dudenhausen JW.

N Engl J Med. 2010 May 13;362(19):1840-1; author reply 1841-2. No abstract available.

PMID:
20468084
31.

Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding.

Plagemann A, Roepke K, Harder T, Brunn M, Harder A, Wittrock-Staar M, Ziska T, Schellong K, Rodekamp E, Melchior K, Dudenhausen JW.

J Perinat Med. 2010 Jul;38(4):393-400. doi: 10.1515/JPM.2010.051.

PMID:
20443665
32.

Birth weight and risk of neuroblastoma: a meta-analysis.

Harder T, Plagemann A, Harder A.

Int J Epidemiol. 2010 Jun;39(3):746-56. doi: 10.1093/ije/dyq040. Epub 2010 Mar 17.

PMID:
20236985
33.

Mitogenic effect of insulin and developmental programming.

Van Assche FA, Devlieger R, Harder T, Plagemann A.

Diabetologia. 2010 Jun;53(6):1243. doi: 10.1007/s00125-010-1712-1. Epub 2010 Mar 12. No abstract available.

PMID:
20225130
34.

Predictors of overweight during childhood in offspring of parents with type 1 diabetes: Response to Hummel et al.

Rodekamp E, Harder T, Dudenhausen JW, Plagemann A.

Diabetes Care. 2009 Nov;32(11):e140. doi: 10.2337/dc09-1234. No abstract available.

PMID:
19875603
35.

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome.

Plagemann A, Harder T, Brunn M, Harder A, Roepke K, Wittrock-Staar M, Ziska T, Schellong K, Rodekamp E, Melchior K, Dudenhausen JW.

J Physiol. 2009 Oct 15;587(Pt 20):4963-76. doi: 10.1113/jphysiol.2009.176156. Epub 2009 Sep 1.

36.

Birth weight and type 2 diabetes in adults.

Plagemann A, Harder T.

JAMA. 2009 Apr 15;301(15):1540; author reply 1540-1. doi: 10.1001/jama.2009.486. No abstract available.

PMID:
19366769
37.

Birth weight, early weight gain, and subsequent risk of type 1 diabetes: systematic review and meta-analysis.

Harder T, Roepke K, Diller N, Stechling Y, Dudenhausen JW, Plagemann A.

Am J Epidemiol. 2009 Jun 15;169(12):1428-36. doi: 10.1093/aje/kwp065. Epub 2009 Apr 10. Review.

PMID:
19363100
38.

[Fetal programming by disturbed intrauterine environment - fundamental mechanisms exemplified by the regulation of body weight and metabolism].

Plagemann A, Harder T, Schellong K, Rodekamp E, Dudenhausen JW.

Gynakol Geburtshilfliche Rundsch. 2008;48(4):215-24. doi: 10.1159/000154805. Epub 2008 Dec 3. Review. German.

PMID:
19096218
39.

Hormonal programming in perinatal life: leptin and beyond.

Plagemann A, Harder T.

Br J Nutr. 2009 Jan;101(2):151-2. doi: 10.1017/S0007114508024021. Epub 2008 Aug 5. No abstract available.

PMID:
18680628
40.

Birth weight and subsequent risk of childhood primary brain tumors: a meta-analysis.

Harder T, Plagemann A, Harder A.

Am J Epidemiol. 2008 Aug 15;168(4):366-73. doi: 10.1093/aje/kwn144. Epub 2008 Jun 25.

PMID:
18579539
41.

Correspondence (letter to the editor): Deceptive Safety.

Plagemann A, Harder T, Dudenhausen JW.

Dtsch Arztebl Int. 2008 May;105(19):362. doi: 10.3238/arztebl.2008.0362. Epub 2008 May 9. No abstract available.

42.

Breast feeding and the risk of obesity and related metabolic diseases in the child.

Plagemann A, Harder T.

Metab Syndr Relat Disord. 2005 Fall;3(3):222-32. doi: 10.1089/met.2005.3.222.

PMID:
18370791
43.

A matter of insulin: developmental programming of body weight regulation.

Plagemann A.

J Matern Fetal Neonatal Med. 2008 Mar;21(3):143-8. doi: 10.1080/14767050801929869. Review.

PMID:
18297568
44.

Intrauterine growth restriction in a rodent model and developmental programming of the metabolic syndrome: a critical appraisal of the experimental evidence.

Neitzke U, Harder T, Schellong K, Melchior K, Ziska T, Rodekamp E, Dudenhausen JW, Plagemann A.

Placenta. 2008 Mar;29(3):246-54. doi: 10.1016/j.placenta.2007.11.014. Epub 2008 Jan 22.

PMID:
18207235
45.

The diabetic pregnancy, macrosomia, and perinatal nutritional programming.

Plagemann A, Harder T, Dudenhausen JW.

Nestle Nutr Workshop Ser Pediatr Program. 2008;61:91-102. doi: 10.1159/0000113179. Review.

PMID:
18196947
46.

Uterine vascular function in a transgenic preeclampsia rat model.

Verlohren S, Niehoff M, Hering L, Geusens N, Herse F, Tintu AN, Plagemann A, LeNoble F, Pijnenborg R, Muller DN, Luft FC, Dudenhausen JW, Gollasch M, Dechend R.

Hypertension. 2008 Feb;51(2):547-53. doi: 10.1161/HYPERTENSIONAHA.107.103176. Epub 2008 Jan 14.

PMID:
18195162
47.

Where is the evidence that low birthweight leads to obesity?

Harder T, Schellong K, Stupin J, Dudenhausen JW, Plagemann A.

Lancet. 2007 Jun 2;369(9576):1859. doi: 10.1016/S0140-6736(07)60847-2. No abstract available.

PMID:
17544762
48.
49.

Insulin resistance of hypothalamic arcuate neurons in neonatally overfed rats.

Davidowa H, Plagemann A.

Neuroreport. 2007 Mar 26;18(5):521-4.

PMID:
17496815
50.

Breast-feeding and risk for childhood obesity: response to Mayer-Davis et al.

Plagemann A, Harder T, Rodekamp E, Dudenhausen JW.

Diabetes Care. 2007 Feb;30(2):451-2; author reply 452. No abstract available.

PMID:
17259539

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