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Items: 1 to 50 of 103

1.

Loss of Mecp2 Causes Atypical Synaptic and Molecular Plasticity of Parvalbumin-Expressing Interneurons Reflecting Rett Syndrome-Like Sensorimotor Defects.

Morello N, Schina R, Pilotto F, Phillips M, Melani R, Plicato O, Pizzorusso T, Pozzo-Miller L, Giustetto M.

eNeuro. 2018 Sep 24;5(5). pii: ENEURO.0086-18.2018. doi: 10.1523/ENEURO.0086-18.2018. eCollection 2018 Sep-Oct.

2.

iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome.

Landucci E, Brindisi M, Bianciardi L, Catania LM, Daga S, Croci S, Frullanti E, Fallerini C, Butini S, Brogi S, Furini S, Melani R, Molinaro A, Lorenzetti FC, Imperatore V, Amabile S, Mariani J, Mari F, Ariani F, Pizzorusso T, Pinto AM, Vaccarino FM, Renieri A, Campiani G, Meloni I.

Exp Cell Res. 2018 Jul 15;368(2):225-235. doi: 10.1016/j.yexcr.2018.05.001. Epub 2018 May 4.

PMID:
29730163
3.

Fluoxetine Modulates the Activity of Hypothalamic POMC Neurons via mTOR Signaling.

Barone I, Melani R, Mainardi M, Scabia G, Scali M, Dattilo A, Ceccarini G, Vitti P, Santini F, Maffei L, Pizzorusso T, Maffei M.

Mol Neurobiol. 2018 Apr 16. doi: 10.1007/s12035-018-1052-6. [Epub ahead of print]

PMID:
29663284
4.

CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder.

Trazzi S, De Franceschi M, Fuchs C, Bastianini S, Viggiano R, Lupori L, Mazziotti R, Medici G, Lo Martire V, Ren E, Rimondini R, Zoccoli G, Bartesaghi R, Pizzorusso T, Ciani E.

Hum Mol Genet. 2018 May 1;27(9):1572-1592. doi: 10.1093/hmg/ddy064.

PMID:
29474534
5.

The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF.

Scabia G, Barone I, Mainardi M, Ceccarini G, Scali M, Buzzigoli E, Dattilo A, Vitti P, Gastaldelli A, Santini F, Pizzorusso T, Maffei L, Maffei M.

Sci Rep. 2018 Jan 29;8(1):1781. doi: 10.1038/s41598-018-19886-x.

6.

Focal Stroke in the Developing Rat Motor Cortex Induces Age- and Experience-Dependent Maladaptive Plasticity of Corticospinal System.

Gennaro M, Mattiello A, Mazziotti R, Antonelli C, Gherardini L, Guzzetta A, Berardi N, Cioni G, Pizzorusso T.

Front Neural Circuits. 2017 Jun 29;11:47. doi: 10.3389/fncir.2017.00047. eCollection 2017.

7.

Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception.

Mazziotti R, Baroncelli L, Ceglia N, Chelini G, Sala GD, Magnan C, Napoli D, Putignano E, Silingardi D, Tola J, Tognini P, Arthur JSC, Baldi P, Pizzorusso T.

Nat Commun. 2017 May 23;8:15488. doi: 10.1038/ncomms15488.

8.

Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice.

Mazziotti R, Lupori L, Sagona G, Gennaro M, Della Sala G, Putignano E, Pizzorusso T.

Hum Mol Genet. 2017 Jun 15;26(12):2290-2298. doi: 10.1093/hmg/ddx119.

9.

A mouse model for creatine transporter deficiency reveals early onset cognitive impairment and neuropathology associated with brain aging.

Baroncelli L, Molinaro A, Cacciante F, Alessandrì MG, Napoli D, Putignano E, Tola J, Leuzzi V, Cioni G, Pizzorusso T.

Hum Mol Genet. 2016 Oct 1;25(19):4186-4200. doi: 10.1093/hmg/ddw252. Epub 2016 Jul 27.

PMID:
27466184
10.

Visual impairment in FOXG1-mutated individuals and mice.

Boggio EM, Pancrazi L, Gennaro M, Lo Rizzo C, Mari F, Meloni I, Ariani F, Panighini A, Novelli E, Biagioni M, Strettoi E, Hayek J, Rufa A, Pizzorusso T, Renieri A, Costa M.

Neuroscience. 2016 Jun 2;324:496-508. doi: 10.1016/j.neuroscience.2016.03.027. Epub 2016 Mar 19.

PMID:
27001178
11.

Perineuronal Nets and CNS Plasticity and Repair.

Carulli D, Kwok JC, Pizzorusso T.

Neural Plast. 2016;2016:4327082. doi: 10.1155/2016/4327082. Epub 2016 Feb 16. No abstract available.

12.

Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1.

Della Sala G, Putignano E, Chelini G, Melani R, Calcagno E, Michele Ratto G, Amendola E, Gross CT, Giustetto M, Pizzorusso T.

Biol Psychiatry. 2016 Aug 15;80(4):302-311. doi: 10.1016/j.biopsych.2015.08.028. Epub 2015 Sep 3.

13.

Dynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticity.

Tognini P, Napoli D, Pizzorusso T.

Front Cell Neurosci. 2015 Aug 25;9:331. doi: 10.3389/fncel.2015.00331. eCollection 2015. Review.

14.

Experience-dependent DNA methylation regulates plasticity in the developing visual cortex.

Tognini P, Napoli D, Tola J, Silingardi D, Della Ragione F, D'Esposito M, Pizzorusso T.

Nat Neurosci. 2015 Jul;18(7):956-8. doi: 10.1038/nn.4026. Epub 2015 May 25.

PMID:
26005848
15.

Editorial for "Regulatory RNAs in the nervous system".

Cellerino A, Bally-Cuif L, Pizzorusso T.

Front Cell Neurosci. 2015 Feb 10;9:38. doi: 10.3389/fncel.2015.00038. eCollection 2015. No abstract available.

16.

A novel mouse model of creatine transporter deficiency.

Baroncelli L, Alessandrì MG, Tola J, Putignano E, Migliore M, Amendola E, Gross C, Leuzzi V, Cioni G, Pizzorusso T.

F1000Res. 2014 Sep 29;3:228. doi: 10.12688/f1000research.5369.1. eCollection 2014.

17.

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology.

Yang S, Cacquevel M, Saksida LM, Bussey TJ, Schneider BL, Aebischer P, Melani R, Pizzorusso T, Fawcett JW, Spillantini MG.

Exp Neurol. 2015 Mar;265:48-58. doi: 10.1016/j.expneurol.2014.11.013. Epub 2014 Dec 4.

18.

Mapping pathological phenotypes in a mouse model of CDKL5 disorder.

Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Vyssotski AL, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross CT.

PLoS One. 2014 May 16;9(5):e91613. doi: 10.1371/journal.pone.0091613. eCollection 2014.

19.

Inflammatory lung disease in Rett syndrome.

De Felice C, Rossi M, Leoncini S, Chisci G, Signorini C, Lonetti G, Vannuccini L, Spina D, Ginori A, Iacona I, Cortelazzo A, Pecorelli A, Valacchi G, Ciccoli L, Pizzorusso T, Hayek J.

Mediators Inflamm. 2014;2014:560120. doi: 10.1155/2014/560120. Epub 2014 Mar 17.

20.

p140Cap regulates memory and synaptic plasticity through Src-mediated and citron-N-mediated actin reorganization.

Repetto D, Camera P, Melani R, Morello N, Russo I, Calcagno E, Tomasoni R, Bianchi F, Berto G, Giustetto M, Berardi N, Pizzorusso T, Matteoli M, Di Stefano P, Missler M, Turco E, Di Cunto F, Defilippi P.

J Neurosci. 2014 Jan 22;34(4):1542-53. doi: 10.1523/JNEUROSCI.2341-13.2014.

21.

Functionalized carbon nanotubes in the brain: cellular internalization and neuroinflammatory responses.

Bardi G, Nunes A, Gherardini L, Bates K, Al-Jamal KT, Gaillard C, Prato M, Bianco A, Pizzorusso T, Kostarelos K.

PLoS One. 2013 Nov 18;8(11):e80964. doi: 10.1371/journal.pone.0080964. eCollection 2013.

22.

Environment, leptin sensitivity, and hypothalamic plasticity.

Mainardi M, Pizzorusso T, Maffei M.

Neural Plast. 2013;2013:438072. doi: 10.1155/2013/438072. Epub 2013 Jul 18. Review.

23.

Perilesional treatment with chondroitinase ABC and motor training promote functional recovery after stroke in rats.

Gherardini L, Gennaro M, Pizzorusso T.

Cereb Cortex. 2015 Jan;25(1):202-12. doi: 10.1093/cercor/bht217. Epub 2013 Aug 19.

PMID:
23960208
24.

System consolidation of spatial memories in mice: effects of enriched environment.

Bonaccorsi J, Cintoli S, Mastrogiacomo R, Baldanzi S, Braschi C, Pizzorusso T, Cenni MC, Berardi N.

Neural Plast. 2013;2013:956312. doi: 10.1155/2013/956312. Epub 2013 Jul 7.

25.

Synaptic plasticity and signaling in Rett syndrome.

Della Sala G, Pizzorusso T.

Dev Neurobiol. 2014 Feb;74(2):178-96. doi: 10.1002/dneu.22114. Epub 2013 Oct 21.

26.

Vascular dysfunction in a mouse model of Rett syndrome and effects of curcumin treatment.

Panighini A, Duranti E, Santini F, Maffei M, Pizzorusso T, Funel N, Taddei S, Bernardini N, Ippolito C, Virdis A, Costa M.

PLoS One. 2013 May 21;8(5):e64863. doi: 10.1371/journal.pone.0064863. Print 2013.

27.

Depletion of perineuronal nets enhances recognition memory and long-term depression in the perirhinal cortex.

Romberg C, Yang S, Melani R, Andrews MR, Horner AE, Spillantini MG, Bussey TJ, Fawcett JW, Pizzorusso T, Saksida LM.

J Neurosci. 2013 Apr 17;33(16):7057-65. doi: 10.1523/JNEUROSCI.6267-11.2013.

28.

Novel siRNA delivery strategy: a new "strand" in CNS translational medicine?

Gherardini L, Bardi G, Gennaro M, Pizzorusso T.

Cell Mol Life Sci. 2014 Jan;71(1):1-20. doi: 10.1007/s00018-013-1310-8. Epub 2013 Mar 19. Review.

PMID:
23508806
29.

Extracellular matrix inhibits structural and functional plasticity of dendritic spines in the adult visual cortex.

de Vivo L, Landi S, Panniello M, Baroncelli L, Chierzi S, Mariotti L, Spolidoro M, Pizzorusso T, Maffei L, Ratto GM.

Nat Commun. 2013;4:1484. doi: 10.1038/ncomms2491.

PMID:
23403561
30.

Molecular mechanisms at the basis of plasticity in the developing visual cortex: epigenetic processes and gene programs.

Maya-Vetencourt JF, Pizzorusso T.

J Exp Neurosci. 2013 Oct 9;7:75-83. doi: 10.4137/JEN.S12958. eCollection 2013. Review.

31.

In vivo distribution and toxicity of PAMAM dendrimers in the central nervous system depend on their surface chemistry.

Albertazzi L, Gherardini L, Brondi M, Sulis Sato S, Bifone A, Pizzorusso T, Ratto GM, Bardi G.

Mol Pharm. 2013 Jan 7;10(1):249-60. doi: 10.1021/mp300391v. Epub 2012 Dec 4.

PMID:
23163881
32.

In vivo degradation of functionalized carbon nanotubes after stereotactic administration in the brain cortex.

Nunes A, Bussy C, Gherardini L, Meneghetti M, Herrero MA, Bianco A, Prato M, Pizzorusso T, Al-Jamal KT, Kostarelos K.

Nanomedicine (Lond). 2012 Oct;7(10):1485-94. doi: 10.2217/nnm.12.33. Epub 2012 Jun 19.

PMID:
22712575
33.

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome.

Landi S, Putignano E, Boggio EM, Giustetto M, Pizzorusso T, Ratto GM.

Sci Rep. 2011;1:45. doi: 10.1038/srep00045. Epub 2011 Jul 25.

34.

ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex.

Silingardi D, Angelucci A, De Pasquale R, Borsotti M, Squitieri G, Brambilla R, Putignano E, Pizzorusso T, Berardi N.

Front Behav Neurosci. 2011 Dec 28;5:84. doi: 10.3389/fnbeh.2011.00084. eCollection 2011.

35.

Carbon nanotube-mediated wireless cell permeabilization: drug and gene uptake.

Raffa V, Gherardini L, Vittorio O, Bardi G, Ziaei A, Pizzorusso T, Riggio C, Nitodas S, Karachalios T, Al-Jamal KT, Kostarelos K, Costa M, Cuschieri A.

Nanomedicine (Lond). 2011 Dec;6(10):1709-18. doi: 10.2217/nnm.11.62.

PMID:
22122583
36.

MicroRNA212/132 family: molecular transducer of neuronal function and plasticity.

Tognini P, Pizzorusso T.

Int J Biochem Cell Biol. 2012 Jan;44(1):6-10. doi: 10.1016/j.biocel.2011.10.015. Epub 2011 Nov 2. Review.

PMID:
22062950
37.

GABAergic circuit development and its implication for CNS disorders.

Di Cristo G, Pizzorusso T, Cancedda L, Sernagor E.

Neural Plast. 2011;2011:623705. doi: 10.1155/2011/623705. Epub 2011 Oct 17. No abstract available.

38.

Experience-dependent expression of miR-132 regulates ocular dominance plasticity.

Tognini P, Putignano E, Coatti A, Pizzorusso T.

Nat Neurosci. 2011 Sep 4;14(10):1237-9. doi: 10.1038/nn.2920.

39.

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

Leo L, Gherardini L, Barone V, De Fusco M, Pietrobon D, Pizzorusso T, Casari G.

PLoS Genet. 2011 Jun;7(6):e1002129. doi: 10.1371/journal.pgen.1002129. Epub 2011 Jun 23.

40.

Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing.

Al-Jamal KT, Gherardini L, Bardi G, Nunes A, Guo C, Bussy C, Herrero MA, Bianco A, Prato M, Kostarelos K, Pizzorusso T.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):10952-7. doi: 10.1073/pnas.1100930108. Epub 2011 Jun 20.

41.

Inhibition of matrix metalloproteinases prevents the potentiation of nondeprived-eye responses after monocular deprivation in juvenile rats.

Spolidoro M, Putignano E, Munafò C, Maffei L, Pizzorusso T.

Cereb Cortex. 2012 Mar;22(3):725-34. doi: 10.1093/cercor/bhr158. Epub 2011 Jun 17.

PMID:
21685398
42.

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

Ricciardi S, Boggio EM, Grosso S, Lonetti G, Forlani G, Stefanelli G, Calcagno E, Morello N, Landsberger N, Biffo S, Pizzorusso T, Giustetto M, Broccoli V.

Hum Mol Genet. 2011 Mar 15;20(6):1182-96. doi: 10.1093/hmg/ddq563. Epub 2011 Jan 6.

PMID:
21212100
43.

A sensitive period for environmental regulation of eating behavior and leptin sensitivity.

Mainardi M, Scabia G, Vottari T, Santini F, Pinchera A, Maffei L, Pizzorusso T, Maffei M.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16673-8. doi: 10.1073/pnas.0911832107. Epub 2010 Sep 7.

44.

Animals lacking link protein have attenuated perineuronal nets and persistent plasticity.

Carulli D, Pizzorusso T, Kwok JC, Putignano E, Poli A, Forostyak S, Andrews MR, Deepa SS, Glant TT, Fawcett JW.

Brain. 2010 Aug;133(Pt 8):2331-47. doi: 10.1093/brain/awq145. Epub 2010 Jun 20.

PMID:
20566484
45.

Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivation.

Silingardi D, Scali M, Belluomini G, Pizzorusso T.

Eur J Neurosci. 2010 Jun;31(12):2185-92. doi: 10.1111/j.1460-9568.2010.07261.x. Epub 2010 Jun 14.

PMID:
20550570
46.

The biocompatibility of amino functionalized CdSe/ZnS quantum-dot-Doped SiO2 nanoparticles with primary neural cells and their gene carrying performance.

Bardi G, Malvindi MA, Gherardini L, Costa M, Pompa PP, Cingolani R, Pizzorusso T.

Biomaterials. 2010 Sep;31(25):6555-66. doi: 10.1016/j.biomaterials.2010.04.063.

PMID:
20537383
47.

In vitro and in vivo biocompatibility testing of functionalized carbon nanotubes.

Ciofani G, Raffa V, Vittorio O, Cuschieri A, Pizzorusso T, Costa M, Bardi G.

Methods Mol Biol. 2010;625:67-83. doi: 10.1007/978-1-60761-579-8_7.

PMID:
20422382
48.

Involvement of the parietal cortex in perceptual learning (Eureka effect): an interference approach using rTMS.

Giovannelli F, Silingardi D, Borgheresi A, Feurra M, Amati G, Pizzorusso T, Viggiano MP, Zaccara G, Berardi N, Cincotta M.

Neuropsychologia. 2010 May;48(6):1807-12. doi: 10.1016/j.neuropsychologia.2010.02.031. Epub 2010 Mar 17.

PMID:
20223254
49.

High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice.

van den Maagdenberg AM, Pizzorusso T, Kaja S, Terpolilli N, Shapovalova M, Hoebeek FE, Barrett CF, Gherardini L, van de Ven RC, Todorov B, Broos LA, Tottene A, Gao Z, Fodor M, De Zeeuw CI, Frants RR, Plesnila N, Plomp JJ, Pietrobon D, Ferrari MD.

Ann Neurol. 2010 Jan;67(1):85-98. doi: 10.1002/ana.21815.

PMID:
20186955
50.

Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.

Lonetti G, Angelucci A, Morando L, Boggio EM, Giustetto M, Pizzorusso T.

Biol Psychiatry. 2010 Apr 1;67(7):657-65. doi: 10.1016/j.biopsych.2009.12.022. Epub 2010 Feb 20.

PMID:
20172507

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