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Items: 21


Human γδ T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation.

Sant S, Jenkins MR, Dash P, Watson KA, Wang Z, Pizzolla A, Koutsakos M, Nguyen TH, Lappas M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Kotsimbos TC, Cheng AC, Wakim L, Doherty PC, Thomas PG, Loh L, Kedzierska K.

Clin Transl Immunology. 2019 Sep 23;8(9):e1079. doi: 10.1002/cti2.1079. eCollection 2019.


Zymosan by-passes the requirement for pulmonary antigen encounter in lung tissue-resident memory CD8+ T cell development.

Caminschi I, Lahoud MH, Pizzolla A, Wakim LM.

Mucosal Immunol. 2019 Mar;12(2):403-412. doi: 10.1038/s41385-018-0124-2. Epub 2019 Jan 21.


Memory T Cell Dynamics in the Lung during Influenza Virus Infection.

Pizzolla A, Wakim LM.

J Immunol. 2019 Jan 15;202(2):374-381. doi: 10.4049/jimmunol.1800979. Review.


Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice.

Fuglsang E, Pizzolla A, Krych L, Nielsen DS, Brooks AG, Frøkiær H, Reading PC.

Front Cell Infect Microbiol. 2018 Sep 12;8:319. doi: 10.3389/fcimb.2018.00319. eCollection 2018.


Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Sant S, Grzelak L, Wang Z, Pizzolla A, Koutsakos M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Wakim LM, Rossjohn J, Gras S, Richards M, Xu J, Thomas PG, Loh L, Nguyen THO, Kedzierska K.

Front Immunol. 2018 Jun 27;9:1453. doi: 10.3389/fimmu.2018.01453. eCollection 2018.


Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Pizzolla A, Nguyen TH, Sant S, Jaffar J, Loudovaris T, Mannering SI, Thomas PG, Westall GP, Kedzierska K, Wakim LM.

J Clin Invest. 2018 Feb 1;128(2):721-733. doi: 10.1172/JCI96957. Epub 2018 Jan 8.


Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Pizzolla A, Nguyen THO, Smith JM, Brooks AG, Kedzieska K, Heath WR, Reading PC, Wakim LM.

Sci Immunol. 2017 Jun 2;2(12). pii: eaam6970. doi: 10.1126/sciimmunol.aam6970.


Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells.

Pizzolla A, Wang Z, Groom JR, Kedzierska K, Brooks AG, Reading PC, Wakim LM.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5225-5230. doi: 10.1073/pnas.1620194114. Epub 2017 May 1.


Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus.

Pizzolla A, Smith JM, Brooks AG, Reading PC.

J Leukoc Biol. 2017 Apr;101(4):851-861. doi: 10.1189/jlb.4MR0716-290R. Epub 2016 Nov 3. Review.


High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance.

Pizzolla A, Oh DY, Luong S, Prickett SR, Henstridge DC, Febbraio MA, O'Hehir RE, Rolland JM, Hardy CL.

PLoS One. 2016 Aug 2;11(8):e0160407. doi: 10.1371/journal.pone.0160407. eCollection 2016.


Neutralizing inhibitors in the airways of naïve ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses.

Job ER, Pizzolla A, Nebl T, Short KR, Deng YM, Carolan L, Laurie KL, Brooks AG, Reading PC.

Virology. 2016 Jul;494:143-57. doi: 10.1016/j.virol.2016.01.024. Epub 2016 Apr 26.


Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8+ T Cell Priming.

Infusini G, Smith JM, Yuan H, Pizzolla A, Ng WC, Londrigan SL, Haque A, Reading PC, Villadangos JA, Wakim LM.

PLoS One. 2015 Nov 23;10(11):e0143539. doi: 10.1371/journal.pone.0143539. eCollection 2015.


Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.

Khmaladze Ia, Kelkka T, Guerard S, Wing K, Pizzolla A, Saxena A, Lundqvist K, Holmdahl M, Nandakumar KS, Holmdahl R.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3669-78. doi: 10.1073/pnas.1405798111. Epub 2014 Aug 18.


Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

Kelkka T, Pizzolla A, Laurila JP, Friman T, Gustafsson R, Källberg E, Olsson O, Leanderson T, Rubin K, Salmi M, Jalkanen S, Holmdahl R.

PLoS One. 2013 Dec 16;8(12):e84148. doi: 10.1371/journal.pone.0084148. eCollection 2013.


A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement.

Pizzolla A, Wing K, Holmdahl R.

Am J Pathol. 2013 Oct;183(4):1144-1155. doi: 10.1016/j.ajpath.2013.06.019. Epub 2013 Jul 30.


Hydrogen peroxide as an immunological transmitter regulating autoreactive T cells.

Holmdahl R, Sareila O, Pizzolla A, Winter S, Hagert C, Jaakkola N, Kelkka T, Olsson LM, Wing K, Bäckdahl L.

Antioxid Redox Signal. 2013 Apr 20;18(12):1463-74. doi: 10.1089/ars.2012.4734. Epub 2012 Aug 17. Review.


Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections.

Pizzolla A, Hultqvist M, Nilson B, Grimm MJ, Eneljung T, Jonsson IM, Verdrengh M, Kelkka T, Gjertsson I, Segal BH, Holmdahl R.

J Immunol. 2012 May 15;188(10):5003-11. doi: 10.4049/jimmunol.1103430. Epub 2012 Apr 9.


CD68-expressing cells can prime T cells and initiate autoimmune arthritis in the absence of reactive oxygen species.

Pizzolla A, Gelderman KA, Hultqvist M, Vestberg M, Gustafsson K, Mattsson R, Holmdahl R.

Eur J Immunol. 2011 Feb;41(2):403-12. doi: 10.1002/eji.201040598. Epub 2010 Dec 23.


NOX2 complex-derived ROS as immune regulators.

Sareila O, Kelkka T, Pizzolla A, Hultqvist M, Holmdahl R.

Antioxid Redox Signal. 2011 Oct 15;15(8):2197-208. doi: 10.1089/ars.2010.3635. Epub 2011 Apr 11. Review.


Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species.

Gelderman KA, Hultqvist M, Pizzolla A, Zhao M, Nandakumar KS, Mattsson R, Holmdahl R.

J Clin Invest. 2007 Oct;117(10):3020-8.


Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.

Gelderman KA, Hultqvist M, Olsson LM, Bauer K, Pizzolla A, Olofsson P, Holmdahl R.

Antioxid Redox Signal. 2007 Oct;9(10):1541-67. Review.


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