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Items: 1 to 50 of 54

1.

Shortening heparan sulfate chains prolongs survival and reduces parenchymal plaques in prion disease caused by mobile, ADAM10-cleaved prions.

Aguilar-Calvo P, Sevillano AM, Bapat J, Soldau K, Sandoval DR, Altmeppen HC, Linsenmeier L, Pizzo DP, Geschwind MD, Sanchez H, Appleby BS, Cohen ML, Safar JG, Edland SD, Glatzel M, Nilsson KPR, Esko JD, Sigurdson CJ.

Acta Neuropathol. 2019 Oct 31. doi: 10.1007/s00401-019-02085-x. [Epub ahead of print]

PMID:
31673874
2.

Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability.

Hingorani DV, Doan MK, Camargo MF, Aguilera J, Song SM, Pizzo D, Scanderbeg DJ, Cohen EEW, Lowy AM, Adams SR, Advani SJ.

Mol Cancer Ther. 2020 Jan;19(1):157-167. doi: 10.1158/1535-7163.MCT-18-1302. Epub 2019 Oct 9.

3.

Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting ONECUT2.

Shen M, Dong C, Ruan X, Yan W, Cao M, Pizzo D, Wu X, Yang L, Liu L, Ren X, Wang SE.

Cancer Res. 2019 Jul 15;79(14):3608-3621. doi: 10.1158/0008-5472.CAN-18-4055. Epub 2019 May 22.

PMID:
31118200
4.

Reply to: "Finding fibroblast growth factor 19 during cholestasis: Does x mark the spot?

Brandl K, Hartmann P, Jih LJ, Pizzo DP, Schnabl B.

J Hepatol. 2018 Dec;69(6):1400-1401. doi: 10.1016/j.jhep.2018.09.017. Epub 2018 Oct 6. No abstract available.

PMID:
30301625
5.

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.

Yan W, Wu X, Zhou W, Fong MY, Cao M, Liu J, Liu X, Chen CH, Fadare O, Pizzo DP, Wu J, Liu L, Liu X, Chin AR, Ren X, Chen Y, Locasale JW, Wang SE.

Nat Cell Biol. 2018 May;20(5):597-609. doi: 10.1038/s41556-018-0083-6. Epub 2018 Apr 16.

6.

Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis.

Brandl K, Hartmann P, Jih LJ, Pizzo DP, Argemi J, Ventura-Cots M, Coulter S, Liddle C, Ling L, Rossi SJ, DePaoli AM, Loomba R, Mehal WZ, Fouts DE, Lucey MR, Bosques-Padilla F, Mathurin P, Louvet A, Garcia-Tsao G, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross D, Stärkel P, Ho SB, Bataller R, Schnabl B.

J Hepatol. 2018 Aug;69(2):396-405. doi: 10.1016/j.jhep.2018.03.031. Epub 2018 Apr 12.

7.

Chemotherapy Induces Breast Cancer Stemness in Association with Dysregulated Monocytosis.

Liu L, Yang L, Yan W, Zhai J, Pizzo DP, Chu P, Chin AR, Shen M, Dong C, Ruan X, Ren X, Somlo G, Wang SE.

Clin Cancer Res. 2018 May 15;24(10):2370-2382. doi: 10.1158/1078-0432.CCR-17-2545. Epub 2018 Mar 2.

8.

The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres.

Gilder AS, Natali L, Van Dyk DM, Zalfa C, Banki MA, Pizzo DP, Wang H, Klemke RL, Mantuano E, Gonias SL.

Sci Rep. 2018 Feb 14;8(1):2982. doi: 10.1038/s41598-018-21358-1.

9.

Sirtuin1 is required for proper trophoblast differentiation and placental development in mice.

Arul Nambi Rajan K, Khater M, Soncin F, Pizzo D, Moretto-Zita M, Pham J, Stus O, Iyer P, Tache V, Laurent LC, Parast MM.

Placenta. 2018 Feb;62:1-8. doi: 10.1016/j.placenta.2017.12.002. Epub 2017 Dec 7.

10.

Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development.

Soncin F, Khater M, To C, Pizzo D, Farah O, Wakeland A, Arul Nambi Rajan K, Nelson KK, Chang CW, Moretto-Zita M, Natale DR, Laurent LC, Parast MM.

Development. 2018 Jan 29;145(2). pii: dev156273. doi: 10.1242/dev.156273.

11.

Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.

Saberi S, Stauffer JE, Jiang J, Garcia SD, Taylor AE, Schulte D, Ohkubo T, Schloffman CL, Maldonado M, Baughn M, Rodriguez MJ, Pizzo D, Cleveland D, Ravits J.

Acta Neuropathol. 2018 Mar;135(3):459-474. doi: 10.1007/s00401-017-1793-8. Epub 2017 Dec 1.

12.

Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.

Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S.

Acta Neuropathol. 2017 Jun;133(6):907-922. doi: 10.1007/s00401-017-1698-6. Epub 2017 Mar 29.

13.

Misfolded SOD1 is not a primary component of sporadic ALS.

Da Cruz S, Bui A, Saberi S, Lee SK, Stauffer J, McAlonis-Downes M, Schulte D, Pizzo DP, Parone PA, Cleveland DW, Ravits J.

Acta Neuropathol. 2017 Jul;134(1):97-111. doi: 10.1007/s00401-017-1688-8. Epub 2017 Feb 28.

14.

Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner.

Wakeland AK, Soncin F, Moretto-Zita M, Chang CW, Horii M, Pizzo D, Nelson KK, Laurent LC, Parast MM.

Am J Pathol. 2017 Apr;187(4):767-780. doi: 10.1016/j.ajpath.2016.11.018. Epub 2017 Feb 4.

15.

Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells.

Campana WM, Mantuano E, Azmoon P, Henry K, Banki MA, Kim JH, Pizzo DP, Gonias SL.

FASEB J. 2017 Apr;31(4):1744-1755. doi: 10.1096/fj.201601121R. Epub 2017 Jan 10.

16.

Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease.

Horii M, Li Y, Wakeland AK, Pizzo DP, Nelson KK, Sabatini K, Laurent LC, Liu Y, Parast MM.

Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):E3882-91. doi: 10.1073/pnas.1604747113. Epub 2016 Jun 20.

17.

Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.

Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp J, Kritzik M, Sicklick J, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek M, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T.

Nature. 2016 Jun 16;534(7607):407-411. doi: 10.1038/nature17988. Epub 2016 Jun 6.

18.

Maternal obesity and sex-specific differences in placental pathology.

Leon-Garcia SM, Roeder HA, Nelson KK, Liao X, Pizzo DP, Laurent LC, Parast MM, LaCoursiere DY.

Placenta. 2016 Feb;38:33-40. doi: 10.1016/j.placenta.2015.12.006. Epub 2015 Dec 15.

PMID:
26907380
19.

Gene Expression Profiling Reveals a Novel Regulatory Role for Sox21 Protein in Mouse Trophoblast Stem Cell Differentiation.

Moretto Zita M, Soncin F, Natale D, Pizzo D, Parast M.

J Biol Chem. 2015 Dec 11;290(50):30152-62. doi: 10.1074/jbc.M115.659094. Epub 2015 Oct 21.

20.

Selective coexpression of VEGF receptor 2 in EGFRvIII-positive glioblastoma cells prevents cellular senescence and contributes to their aggressive nature.

Jones KA, Gilder AS, Lam MS, Du N, Banki MA, Merati A, Pizzo DP, VandenBerg SR, Gonias SL.

Neuro Oncol. 2016 May;18(5):667-78. doi: 10.1093/neuonc/nov243. Epub 2015 Sep 29.

21.

Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.

Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4055-64. doi: 10.1073/pnas.1501967112. Epub 2015 Jul 9.

22.

Integrin α4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma.

Young SA, McCabe KE, Bartakova A, Delaney J, Pizzo DP, Newbury RO, Varner JA, Schlaepfer DD, Stupack DG.

PLoS One. 2015 May 14;10(5):e0120815. doi: 10.1371/journal.pone.0120815. eCollection 2015.

23.

A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.

Wykosky J, Hu J, Gomez GG, Taylor T, Villa GR, Pizzo D, VandenBerg SR, Thorne AH, Chen CC, Mischel PS, Gonias SL, Cavenee WK, Furnari FB.

Cancer Res. 2015 Jan 15;75(2):394-404. doi: 10.1158/0008-5472.CAN-14-2004. Epub 2014 Nov 28.

24.

Intracerebroventricular administration of nerve growth factor induces gliogenesis in sensory ganglia, dorsal root, and within the dorsal root entry zone.

Schlachetzki JC, Pizzo DP, Morrissette DA, Winkler J.

Biomed Res Int. 2014;2014:704259. doi: 10.1155/2014/704259. Epub 2014 Mar 16.

25.

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration.

Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, Drenner K, Artates JW, McAlonis-Downes M, Markmiller S, Hutt KR, Pizzo DP, Cady J, Harms MB, Baloh RH, Vandenberg SR, Yeo GW, Fu XD, Bennett CF, Cleveland DW, Ravits J.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4530-9. doi: 10.1073/pnas.1318835110. Epub 2013 Oct 29.

26.

BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state.

Li Y, Moretto-Zita M, Soncin F, Wakeland A, Wolfe L, Leon-Garcia S, Pandian R, Pizzo D, Cui L, Nazor K, Loring JF, Crum CP, Laurent LC, Parast MM.

Development. 2013 Oct;140(19):3965-76. doi: 10.1242/dev.092155. Epub 2013 Sep 4.

27.

Myeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors.

Staudt ND, Jo M, Hu J, Bristow JM, Pizzo DP, Gaultier A, VandenBerg SR, Gonias SL.

Cancer Res. 2013 Jul 1;73(13):3902-12. doi: 10.1158/0008-5472.CAN-12-4233. Epub 2013 Apr 30.

28.

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice.

Li N, Wu X, Holzer RG, Lee JH, Todoric J, Park EJ, Ogata H, Gukovskaya AS, Gukovsky I, Pizzo DP, VandenBerg S, Tarin D, Atay C, Arkan MC, Deerinck TJ, Moscat J, Diaz-Meco M, Dawson D, Erkan M, Kleeff J, Karin M.

J Clin Invest. 2013 May;123(5):2231-43. doi: 10.1172/JCI64498. Epub 2013 Apr 8.

29.

Role of connexins in metastatic breast cancer and melanoma brain colonization.

Stoletov K, Strnadel J, Zardouzian E, Momiyama M, Park FD, Kelber JA, Pizzo DP, Hoffman R, VandenBerg SR, Klemke RL.

J Cell Sci. 2013 Feb 15;126(Pt 4):904-13. doi: 10.1242/jcs.112748. Epub 2013 Jan 15.

30.

Spongiform change in dementia with Lewy bodies and Alzheimer disease.

Sherzai A, Edland SD, Masliah E, Hansen L, Pizzo DP, Sherzai A, Corey-Bloom J.

Alzheimer Dis Assoc Disord. 2013 Apr-Jun;27(2):157-61. doi: 10.1097/WAD.0b013e318256d507.

PMID:
22546782
31.

Predictors of diagnostic success with renal artery duplex ultrasonography.

Hedayati N, Del Pizzo DJ, Harris SE, Kuskowski M, Pevec WC, Lee ES, Pifer C, Dawson DL.

Ann Vasc Surg. 2011 May;25(4):515-9. doi: 10.1016/j.avsg.2011.02.008.

PMID:
21549921
32.

A rare cause of recurrent spontaneous pneumothorax.

Savasta S, Leoni MC, Strocchio L, Pizzo D, Spartà MV, Lima M, Valli M, Marchi A.

Clin Pediatr (Phila). 2011 May;50(5):456-8. doi: 10.1177/0009922810385571. No abstract available.

PMID:
21525091
33.

TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1.

Morse E, Schroth J, You YH, Pizzo DP, Okada S, Ramachandrarao S, Vallon V, Sharma K, Cunard R.

Am J Physiol Renal Physiol. 2010 Nov;299(5):F965-72. doi: 10.1152/ajprenal.00236.2010. Epub 2010 Jul 21.

34.

[Adipocytokines: potential biomarkers for childhood obesity and anorexia nervosa].

Leoni MC, Pizzo D, Marchi A.

Minerva Pediatr. 2010 Apr;62(2):171-8. Review. Italian.

PMID:
20440237
35.

The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis.

Arndt MA, Battaglia V, Parisi E, Lortie MJ, Isome M, Baskerville C, Pizzo DP, Ientile R, Colombatto S, Toninello A, Satriano J.

Am J Physiol Cell Physiol. 2009 Jun;296(6):C1411-9. doi: 10.1152/ajpcell.00529.2008. Epub 2009 Mar 25.

36.

Nerve growth factor promotes survival of new neurons in the adult hippocampus.

Frielingsdorf H, Simpson DR, Thal LJ, Pizzo DP.

Neurobiol Dis. 2007 Apr;26(1):47-55. Epub 2006 Dec 20.

PMID:
17270453
37.

High-fat diet impairs hippocampal neurogenesis in male rats.

Lindqvist A, Mohapel P, Bouter B, Frielingsdorf H, Pizzo D, Brundin P, Erlanson-Albertsson C.

Eur J Neurol. 2006 Dec;13(12):1385-8.

PMID:
17116226
38.

The septohippocampal cholinergic system and spatial working memory in the Morris water maze.

Frielingsdorf H, Thal LJ, Pizzo DP.

Behav Brain Res. 2006 Mar 15;168(1):37-46. Epub 2005 Dec 5.

PMID:
16330106
39.

Regulatable acetylcholine-producing fibroblasts enhance cognitive performance.

Pizzo DP, Coufal NG, Lortie MJ, Gage FH, Thal LJ.

Mol Ther. 2006 Jan;13(1):175-82. Epub 2005 Sep 26.

40.

Apoptotic signals within the basal forebrain cholinergic neurons in Alzheimer's disease.

Wu CK, Thal L, Pizzo D, Hansen L, Masliah E, Geula C.

Exp Neurol. 2005 Oct;195(2):484-96.

PMID:
16085017
41.

Production of arginine by the kidney is impaired in a model of sepsis: early events following LPS.

Lortie MJ, Satriano J, Gabbai FB, Thareau S, Khang S, Deng A, Pizzo DP, Thomson SC, Blantz RC, Munger KA.

Am J Physiol Regul Integr Comp Physiol. 2004 Dec;287(6):R1434-40. Epub 2004 Aug 12.

42.

Long-term production of choline acetyltransferase in the CNS after transplantation of fibroblasts modified with a regulatable vector.

Pizzo DP, Paban V, Coufal NG, Gage FH, Thal LJ.

Brain Res Mol Brain Res. 2004 Jul 5;126(1):1-13.

PMID:
15207910
43.

Choline transporter 1 maintains cholinergic function in choline acetyltransferase haploinsufficiency.

Brandon EP, Mellott T, Pizzo DP, Coufal N, D'Amour KA, Gobeske K, Lortie M, López-Coviella I, Berse B, Thal LJ, Gage FH, Blusztajn JK.

J Neurosci. 2004 Jun 16;24(24):5459-66.

45.

Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice.

Brandon EP, Lin W, D'Amour KA, Pizzo DP, Dominguez B, Sugiura Y, Thode S, Ko CP, Thal LJ, Gage FH, Lee KF.

J Neurosci. 2003 Jan 15;23(2):539-49.

46.
47.

Mnemonic deficits in animals depend upon the degree of cholinergic deficit and task complexity.

Pizzo DP, Thal LJ, Winkler J.

Exp Neurol. 2002 Sep;177(1):292-305.

PMID:
12429231
48.
49.

Effects of intraventricular transplantation of NGF-secreting cells on cholinergic basal forebrain neurons after partial immunolesion.

Rossner S, Yu J, Pizzo D, Werrbach-Perez K, Schliebs R, Bigl V, Perez-Polo JR.

J Neurosci Res. 1996 Jul 1;45(1):40-56.

PMID:
8811511
50.

Role of the cholinergic system in the regulation of neurotrophin synthesis.

Yu J, Pizzo DP, Hutton LA, Perez-Polo JR.

Brain Res. 1995 Dec 24;705(1-2):247-52.

PMID:
8821756

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