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Items: 39

1.

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells.

Ettari R, Pallio G, Pizzino G, Irrera N, Zappalà M, Maiorana S, Di Chio C, Altavilla D, Squadrito F, Bitto A.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1307-1313. doi: 10.1080/14756366.2019.1594802.

PMID:
31307247
2.

Cadmium-Induced Oxidative Stress Impairs Glycemic Control in Adolescents.

Pizzino G, Irrera N, Bitto A, Pallio G, Mannino F, Arcoraci V, Aliquò F, Minutoli L, De Ponte C, D'andrea P, Squadrito F, Altavilla D.

Oxid Med Cell Longev. 2017;2017:6341671. doi: 10.1155/2017/6341671. Epub 2017 Dec 12.

3.

Dual αvβ3 and αvβ5 blockade attenuates fibrotic and vascular alterations in a murine model of systemic sclerosis.

Bagnato GL, Irrera N, Pizzino G, Santoro D, Roberts WN, Bagnato G, Pallio G, Vaccaro M, Squadrito F, Saitta A, Altavilla D, Bitto A.

Clin Sci (Lond). 2018 Jan 19;132(2):231-242. doi: 10.1042/CS20171426. Print 2018 Jan 31.

PMID:
29237724
4.

Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes.

Bitto A, Irrera N, Pizzino G, Pallio G, Mannino F, Vaccaro M, Arcoraci V, Aliquò F, Minutoli L, Colonna MR, Galeano MR, Brines M, De Ponte C, Collino M, Squadrito F, Altavilla D.

Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):632-639. doi: 10.1016/j.bbadis.2017.12.006. Epub 2017 Dec 7.

5.

Effects of the antagomiRs 15b and 200b on the altered healing pattern of diabetic mice.

Pizzino G, Irrera N, Galfo F, Pallio G, Mannino F, D'amore A, Pellegrino E, Ieni A, Russo GT, Calapai M, Altavilla D, Squadrito F, Bitto A.

Br J Pharmacol. 2018 Feb;175(4):644-655. doi: 10.1111/bph.14113. Epub 2018 Jan 18.

6.

Impairment of elastic properties of the aorta in bicuspid aortic valve: relationship between biomolecular and aortic strain patterns.

Longobardo L, Carerj ML, Pizzino G, Bitto A, Piccione MC, Zucco M, Oreto L, Todaro MC, Calabrò MP, Squadrito F, Di Bella G, Oreto G, Khandheria BK, Carerj S, Zito C.

Eur Heart J Cardiovasc Imaging. 2018 Aug 1;19(8):879-887. doi: 10.1093/ehjci/jex224.

PMID:
29029085
7.

Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model.

Pizzino G, Irrera N, Galfo F, Oteri G, Atteritano M, Pallio G, Mannino F, D'Amore A, Pellegrino E, Aliquò F, Anastasi GP, Cutroneo G, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2017 Sep 5;8:558. doi: 10.3389/fphar.2017.00558. eCollection 2017.

8.

Oxidative Stress: Harms and Benefits for Human Health.

Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A.

Oxid Med Cell Longev. 2017;2017:8416763. doi: 10.1155/2017/8416763. Epub 2017 Jul 27. Review.

9.

Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury.

Irrera N, Pizzino G, Calò M, Pallio G, Mannino F, Famà F, Arcoraci V, Fodale V, David A, Francesca C, Minutoli L, Mazzon E, Bramanti P, Squadrito F, Altavilla D, Bitto A.

Front Pharmacol. 2017 Jul 14;8:459. doi: 10.3389/fphar.2017.00459. eCollection 2017.

10.

Dietary Management of Skin Health: The Role of Genistein.

Irrera N, Pizzino G, D'Anna R, Vaccaro M, Arcoraci V, Squadrito F, Altavilla D, Bitto A.

Nutrients. 2017 Jun 17;9(6). pii: E622. doi: 10.3390/nu9060622. Review.

11.

Pharmacological Activity and Clinical Use of PDRN.

Squadrito F, Bitto A, Irrera N, Pizzino G, Pallio G, Minutoli L, Altavilla D.

Front Pharmacol. 2017 Apr 26;8:224. doi: 10.3389/fphar.2017.00224. eCollection 2017. Review.

12.

Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury.

Squadrito F, Micali A, Rinaldi M, Irrera N, Marini H, Puzzolo D, Pisani A, Lorenzini C, Valenti A, Laurà R, Germanà A, Bitto A, Pizzino G, Pallio G, Altavilla D, Minutoli L.

Front Pharmacol. 2017 Jan 10;7:537. doi: 10.3389/fphar.2016.00537. eCollection 2016.

13.

Takotsubo syndrome and estrogen receptor genes: partners in crime?

Pizzino G, Bitto A, Crea P, Khandheria B, Vriz O, Carerj S, Squadrito F, Minisini R, Citro R, Cusmà-Piccione M, Madaffari A, Andò G, Altavilla D, Zito C.

J Cardiovasc Med (Hagerstown). 2017 Apr;18(4):268-276. doi: 10.2459/JCM.0000000000000500.

PMID:
28118181
14.

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis.

Irrera N, Vaccaro M, Bitto A, Pallio G, Pizzino G, Lentini M, Arcoraci V, Minutoli L, Scuruchi M, Cutroneo G, Anastasi GP, Ettari R, Squadrito F, Altavilla D.

Clin Sci (Lond). 2017 Mar 1;131(6):487-498. doi: 10.1042/CS20160645. Epub 2017 Jan 17.

PMID:
28096316
15.

Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis.

Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Squadrito F, Squadrito G, Pallio S, Anastasi GP, Cutroneo G, Macrì A, Altavilla D.

Front Pharmacol. 2016 Aug 23;7:273. doi: 10.3389/fphar.2016.00273. eCollection 2016.

16.

Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.

Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Minutoli L, Arcoraci V, Squadrito G, Macrì A, Squadrito F, Altavilla D.

Eur J Pharmacol. 2016 Oct 15;789:152-162. doi: 10.1016/j.ejphar.2016.07.033. Epub 2016 Jul 21.

PMID:
27450484
17.

Increased Serum HMGB-1, ICAM-1 and Metalloproteinase-9 Levels in Buerger's Patients.

De Caridi G, Bitto A, Massara M, Pallio G, Pizzino G, Serra R, Altavilla D, Squadrito F, Spinelli F.

Curr Vasc Pharmacol. 2016;14(4):382-7.

PMID:
26935815
18.

Genomic Variations Affecting Biological Effects of Statins.

Bitto A, Pallio G, Messina S, Arcoraci V, Pizzino G, Russo GT, Pallio S, Squadrito F, Altavilla D.

Curr Drug Metab. 2016;17(6):566-72. Review.

PMID:
26892732
19.

Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis.

Bitto A, Bagnato GL, Pizzino G, Roberts WN, Irrera N, Minutoli L, Russo G, Squadrito F, Saitta A, Bagnato GF, Altavilla D.

Free Radic Res. 2016;50(5):514-22. doi: 10.3109/10715762.2016.1149171. Epub 2016 Mar 17.

PMID:
26846205
20.

Erratum: Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood-Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice.

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2016 Jan;149(1):270. doi: 10.1093/toxsci/kfv247. Epub 2015 Dec 3. No abstract available.

PMID:
26637550
21.

Flavocoxid Protects Against Cadmium-Induced Disruption of the Blood–Testis Barrier and Improves Testicular Damage and Germ Cell Impairment in Mice [corrected].

Minutoli L, Micali A, Pisani A, Puzzolo D, Bitto A, Rinaldi M, Pizzino G, Irrera N, Galfo F, Arena S, Pallio G, Mecchio A, Germanà A, Bruschetta D, Laurà R, Magno C, Marini H, Squadrito F, Altavilla D.

Toxicol Sci. 2015 Nov;148(1):311-29. doi: 10.1093/toxsci/kfv185. Epub 2015 Sep 30. Erratum in: Toxicol Sci. 2015 Dec 3;149(1):270.

PMID:
26424772
22.

NLRP3 Inflammasome Involvement in the Organ Damage and Impaired Spermatogenesis Induced by Testicular Ischemia and Reperfusion in Mice.

Minutoli L, Antonuccio P, Irrera N, Rinaldi M, Bitto A, Marini H, Pizzino G, Romeo C, Pisani A, Santoro G, Puzzolo D, Magno C, Squadrito F, Micali A, Altavilla D.

J Pharmacol Exp Ther. 2015 Dec;355(3):370-80. doi: 10.1124/jpet.115.226936. Epub 2015 Sep 25.

PMID:
26407722
23.

Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.

Minutoli L, Arena S, Antonuccio P, Romeo C, Bitto A, Magno C, Rinaldi M, Micali A, Irrera N, Pizzino G, Galfo F, Squadrito F, Altavilla D, Marini H.

Biomed Res Int. 2015;2015:248976. doi: 10.1155/2015/248976. Epub 2015 Aug 4.

24.

Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury.

Irrera N, Bitto A, Pizzino G, Vaccaro M, Squadrito F, Galeano M, Stagno d'Alcontres F, Stagno d'Alcontres F, Buemi M, Minutoli L, Colonna MR, Altavilla D.

Biomed Res Int. 2015;2015:968927. doi: 10.1155/2015/968927. Epub 2015 Jun 4.

25.

A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury.

Minutoli L, Marini H, Rinaldi M, Bitto A, Irrera N, Pizzino G, Pallio G, Calò M, Adamo EB, Trichilo V, Interdonato M, Galfo F, Squadrito F, Altavilla D.

Neuromolecular Med. 2015 Jun;17(2):192-201. doi: 10.1007/s12017-015-8351-0. Epub 2015 Apr 19.

PMID:
25893744
26.

Blockade of the JNK signalling as a rational therapeutic approach to modulate the early and late steps of the inflammatory cascade in polymicrobial sepsis.

Pizzino G, Bitto A, Pallio G, Irrera N, Galfo F, Interdonato M, Mecchio A, De Luca F, Minutoli L, Squadrito F, Altavilla D.

Mediators Inflamm. 2015;2015:591572. doi: 10.1155/2015/591572. Epub 2015 Mar 22.

27.

Propylthiouracil modulates aortic vasculopathy in the oxidative stress model of systemic sclerosis.

Bagnato G, Bitto A, Pizzino G, Roberts WN, Squadrito F, Altavilla D, Bagnato G, Saitta A.

Vascul Pharmacol. 2015 Aug;71:79-83. doi: 10.1016/j.vph.2014.12.006. Epub 2015 Apr 11.

PMID:
25869518
28.

CO2 pneumoperitoneum preserves β-arrestin 2 content and reduces high mobility group box-1 (HMGB-1) expression in an animal model of peritonitis.

Montalto AS, Bitto A, Minutoli L, Impellizzeri P, Costa G, Irrera N, Pizzino G, Squadrito F, Altavilla D, Romeo C.

Oxid Med Cell Longev. 2015;2015:160568. doi: 10.1155/2015/160568. Epub 2015 Feb 24.

29.

Epigenetic modifications due to heavy metals exposure in children living in polluted areas.

Bitto A, Pizzino G, Irrera N, Galfo F, Squadrito F.

Curr Genomics. 2014 Dec;15(6):464-8. doi: 10.2174/138920291506150106153336.

30.

Cadmium delays puberty onset and testis growth in adolescents.

Interdonato M, Pizzino G, Bitto A, Galfo F, Irrera N, Mecchio A, Pallio G, Ramistella V, De Luca F, Santamaria A, Minutoli L, Marini H, Squadrito F, Altavilla D.

Clin Endocrinol (Oxf). 2015 Sep;83(3):357-62. doi: 10.1111/cen.12704. Epub 2015 Jan 15.

PMID:
25521350
31.

Levels of heavy metals in adolescents living in the industrialised area of Milazzo-Valle del Mela (northern Sicily).

Interdonato M, Bitto A, Pizzino G, Irrera N, Pallio G, Mecchio A, Cuspilici A, Minutoli L, Altavilla D, Squadrito F.

J Environ Public Health. 2014;2014:326845. doi: 10.1155/2014/326845. Epub 2014 Sep 23.

32.

Polyethylene glycol formulations show different soft tissue remodeling and angiogenesis features.

Oteri G, Pizzino G, Pisano M, Peditto M, Squadrito F, Bitto A.

Tissue Eng Part A. 2015 Feb;21(3-4):580-5. doi: 10.1089/ten.TEA.2014.0260. Epub 2014 Nov 12.

33.

Flavocoxid, a nutraceutical approach to blunt inflammatory conditions.

Bitto A, Squadrito F, Irrera N, Pizzino G, Pallio G, Mecchio A, Galfo F, Altavilla D.

Mediators Inflamm. 2014;2014:790851. doi: 10.1155/2014/790851. Epub 2014 Aug 24. Review.

34.

Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy).

Pizzino G, Bitto A, Interdonato M, Galfo F, Irrera N, Mecchio A, Pallio G, Ramistella V, De Luca F, Minutoli L, Squadrito F, Altavilla D.

Redox Biol. 2014 May 21;2:686-93. doi: 10.1016/j.redox.2014.05.003. eCollection 2014.

35.

Inhibitors of apoptosis proteins in experimental benign prostatic hyperplasia: effects of serenoa repens, selenium and lycopene.

Minutoli L, Altavilla D, Marini H, Rinaldi M, Irrera N, Pizzino G, Bitto A, Arena S, Cimino S, Squadrito F, Russo GI, Morgia G.

J Biomed Sci. 2014 Mar 10;21:19. doi: 10.1186/1423-0127-21-19.

36.

Inhibition of inflammasome activation improves the impaired pattern of healing in genetically diabetic mice.

Bitto A, Altavilla D, Pizzino G, Irrera N, Pallio G, Colonna MR, Squadrito F.

Br J Pharmacol. 2014 May;171(9):2300-7. doi: 10.1111/bph.12557.

37.

Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.

Bagnato G, Bitto A, Irrera N, Pizzino G, Sangari D, Cinquegrani M, Roberts W, Atteritano M, Altavilla D, Squadrito F, Bagnato G, Saitta A.

Arthritis Res Ther. 2013 Sep 16;15(5):R120. doi: 10.1186/ar4300. Erratum in: Arthritis Res Ther. 2014;16(2):406.

38.

Relaxin improves multiple markers of wound healing and ameliorates the disturbed healing pattern of genetically diabetic mice.

Bitto A, Irrera N, Minutoli L, Calò M, Lo Cascio P, Caccia P, Pizzino G, Pallio G, Micali A, Vaccaro M, Saitta A, Squadrito F, Altavilla D.

Clin Sci (Lond). 2013 Dec;125(12):575-85. doi: 10.1042/CS20130105.

39.

Simvastatin attenuates the development of pulmonary and cutaneous fibrosis in a murine model of systemic sclerosis.

Bagnato G, Bitto A, Pizzino G, Irrera N, Sangari D, Cinquegrani M, Roberts WN, Matucci Cerinic M, Squadrito F, Altavilla D, Bagnato G, Saitta A.

Rheumatology (Oxford). 2013 Aug;52(8):1377-86. doi: 10.1093/rheumatology/ket144. Epub 2013 Apr 25.

PMID:
23620550

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