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Items: 1 to 50 of 94

1.

Estrogen Receptor α Loss-of-Function Protects Female Mice From DSS-Induced Experimental Colitis.

Goodman WA, Havran HL, Quereshy HA, Kuang S, De Salvo C, Pizarro TT.

Cell Mol Gastroenterol Hepatol. 2017 Dec 15;5(4):630-633.e1. doi: 10.1016/j.jcmgh.2017.12.003. eCollection 2018. No abstract available.

2.

The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn's Disease-Like Ileitis.

Rodriguez-Palacios A, Harding A, Menghini P, Himmelman C, Retuerto M, Nickerson KP, Lam M, Croniger CM, McLean MH, Durum SK, Pizarro TT, Ghannoum MA, Ilic S, McDonald C, Cominelli F.

Inflamm Bowel Dis. 2018 Apr 23;24(5):1005-1020. doi: 10.1093/ibd/izy060.

PMID:
29554272
3.

Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn's Disease-Like Ileitis.

Li Z, Buttó LF, Buela KA, Jia LG, Lam M, Ward JD, Pizarro TT, Cominelli F.

Front Immunol. 2018 Mar 1;9:362. doi: 10.3389/fimmu.2018.00362. eCollection 2018.

4.

Uncovering Pathogenic Mechanisms of Inflammatory Bowel Disease Using Mouse Models of Crohn's Disease-Like Ileitis: What is the Right Model?

Cominelli F, Arseneau KO, Rodriguez-Palacios A, Pizarro TT.

Cell Mol Gastroenterol Hepatol. 2017 Mar 6;4(1):19-32. doi: 10.1016/j.jcmgh.2017.02.010. eCollection 2017 Jul. Review.

5.

A novel model of colitis-associated cancer in SAMP1/YitFc mice with Crohn's disease-like ileitis.

Menghini P, Di Martino L, Lopetuso LR, Corridoni D, Webster JC, Xin W, Arseneau KO, Lam M, Pizarro TT, Cominelli F.

PLoS One. 2017 Mar 16;12(3):e0174121. doi: 10.1371/journal.pone.0174121. eCollection 2017.

6.

Interleukin-37: A Peacekeeper at the Intestinal Borders.

Pastorelli L, Pizarro TT.

Dig Dis Sci. 2017 May;62(5):1103-1106. doi: 10.1007/s10620-017-4523-0. No abstract available.

PMID:
28289924
7.

A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach.

Petersen CP, Meyer AR, De Salvo C, Choi E, Schlegel C, Petersen A, Engevik AC, Prasad N, Levy SE, Peebles RS, Pizarro TT, Goldenring JR.

Gut. 2018 May;67(5):805-817. doi: 10.1136/gutjnl-2016-312779. Epub 2017 Feb 14.

8.

Epithelial-specific Toll-like Receptor (TLR)5 Activation Mediates Barrier Dysfunction in Experimental Ileitis.

Lopetuso LR, Jia R, Wang XM, Jia LG, Petito V, Goodman WA, Meddings JB, Cominelli F, Reuter BK, Pizarro TT.

Inflamm Bowel Dis. 2017 Mar;23(3):392-403. doi: 10.1097/MIB.0000000000001035.

PMID:
28146004
9.

γδ T Cells Coexpressing Gut Homing α4β7 and αE Integrins Define a Novel Subset Promoting Intestinal Inflammation.

Do JS, Kim S, Keslar K, Jang E, Huang E, Fairchild RL, Pizarro TT, Min B.

J Immunol. 2017 Jan 15;198(2):908-915. doi: 10.4049/jimmunol.1601060. Epub 2016 Dec 7.

10.

Genetic deletion of the bacterial sensor NOD2 improves murine Crohn's disease-like ileitis independent of functional dysbiosis.

Corridoni D, Rodriguez-Palacios A, Di Stefano G, Di Martino L, Antonopoulos DA, Chang EB, Arseneau KO, Pizarro TT, Cominelli F.

Mucosal Immunol. 2017 Jul;10(4):971-982. doi: 10.1038/mi.2016.98. Epub 2016 Nov 16.

11.

Protective Role for TWEAK/Fn14 in Regulating Acute Intestinal Inflammation and Colitis-Associated Tumorigenesis.

Di Martino L, Dave M, Menghini P, Xin W, Arseneau KO, Pizarro TT, Cominelli F.

Cancer Res. 2016 Nov 15;76(22):6533-6542. doi: 10.1158/0008-5472.CAN-16-0400. Epub 2016 Sep 9.

12.

A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.

Jia LG, Bamias G, Arseneau KO, Burkly LC, Wang EC, Gruszka D, Pizarro TT, Cominelli F.

J Immunol. 2016 Jul 1;197(1):377-86. doi: 10.4049/jimmunol.1502466. Epub 2016 May 27.

13.

Does the association between birth weight and blood pressure increase with age? A longitudinal study in young adults.

Bustos P, Amigo H, Bangdiwala SI, Pizarro T, Rona RJ.

J Hypertens. 2016 Jun;34(6):1062-7. doi: 10.1097/HJH.0000000000000912.

PMID:
27077730
14.

IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.

De Salvo C, Wang XM, Pastorelli L, Mattioli B, Omenetti S, Buela KA, Chowdhry S, Garg RR, Goodman WA, Rodriguez-Palacios A, Smith DE, Abbott DW, Cominelli F, Bamias G, Xin W, Lee JJ, Vecchi M, Pizarro TT.

Am J Pathol. 2016 Apr;186(4):885-98. doi: 10.1016/j.ajpath.2015.11.028. Epub 2016 Feb 22.

15.

KLF6 contributes to myeloid cell plasticity in the pathogenesis of intestinal inflammation.

Goodman WA, Omenetti S, Date D, Di Martino L, De Salvo C, Kim GD, Chowdhry S, Bamias G, Cominelli F, Pizarro TT, Mahabeleshwar GH.

Mucosal Immunol. 2016 Sep;9(5):1250-62. doi: 10.1038/mi.2016.1. Epub 2016 Feb 3.

16.

The Treg/Th17 Axis: A Dynamic Balance Regulated by the Gut Microbiome.

Omenetti S, Pizarro TT.

Front Immunol. 2015 Dec 17;6:639. doi: 10.3389/fimmu.2015.00639. eCollection 2015. Review.

17.

Pathway-based approaches to the treatment of inflammatory bowel disease.

Bamias G, Pizarro TT, Cominelli F.

Transl Res. 2016 Jan;167(1):104-15. doi: 10.1016/j.trsl.2015.09.002. Epub 2015 Sep 7. Review.

18.

Cross-talk between type 3 innate lymphoid cells and the gut microbiota in inflammatory bowel disease.

Buela KA, Omenetti S, Pizarro TT.

Curr Opin Gastroenterol. 2015 Nov;31(6):449-55. doi: 10.1097/MOG.0000000000000217. Review.

19.

Dysregulated intrahepatic CD4+ T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice.

Omenetti S, Brogi M, Goodman WA, Croniger CM, Eid S, Huang AY, Laffi G, Roskams T, Cominelli F, Pinzani M, Pizarro TT.

Cell Mol Gastroenterol Hepatol. 2015 Jul 1;1(4):406-419.

20.

Stereomicroscopic 3D-pattern profiling of murine and human intestinal inflammation reveals unique structural phenotypes.

Rodriguez-Palacios A, Kodani T, Kaydo L, Pietropaoli D, Corridoni D, Howell S, Katz J, Xin W, Pizarro TT, Cominelli F.

Nat Commun. 2015 Jul 8;6:7577. doi: 10.1038/ncomms8577.

21.

IL-33 activates tumor stroma to promote intestinal polyposis.

Maywald RL, Doerner SK, Pastorelli L, De Salvo C, Benton SM, Dawson EP, Lanza DG, Berger NA, Markowitz SD, Lenz HJ, Nadeau JH, Pizarro TT, Heaney JD.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):E2487-96. doi: 10.1073/pnas.1422445112. Epub 2015 Apr 27.

22.

SAMP1/YitFc mice develop ileitis via loss of CCL21 and defects in dendritic cell migration.

Mikulski Z, Johnson R, Shaked I, Kim G, Nowyhed H, Goodman W, Chodaczek G, Pizarro TT, Cominelli F, Ley K.

Gastroenterology. 2015 Apr;148(4):783-793.e5. doi: 10.1053/j.gastro.2015.01.027. Epub 2015 Jan 22.

23.

Impact of left ventricular hypertrophy on troponin release during acute myocardial infarction: new insights from a comprehensive translational study.

Fernández-Jiménez R, Silva J, Martínez-Martínez S, López-Maderuelo MD, Nuno-Ayala M, García-Ruiz JM, García-Álvarez A, Fernández-Friera L, Pizarro TG, García-Prieto J, Sanz-Rosa D, López-Martin G, Fernández-Ortiz A, Macaya C, Fuster V, Redondo JM, Ibanez B.

J Am Heart Assoc. 2015 Jan 21;4(1):e001218. doi: 10.1161/JAHA.114.001218.

24.

Mechanisms and models for intestinal fibrosis in IBD.

De Salvo C, Ray S, Pizarro TT.

Dig Dis. 2014;32 Suppl 1:26-34. doi: 10.1159/000367822. Epub 2014 Dec 17. Review.

PMID:
25531350
25.

Central role of IL-17/Th17 immune responses and the gut microbiota in the pathogenesis of intestinal fibrosis.

Ray S, De Salvo C, Pizarro TT.

Curr Opin Gastroenterol. 2014 Nov;30(6):531-8. doi: 10.1097/MOG.0000000000000119. Review.

26.

In vivo inhibition of RIPK2 kinase alleviates inflammatory disease.

Tigno-Aranjuez JT, Benderitter P, Rombouts F, Deroose F, Bai X, Mattioli B, Cominelli F, Pizarro TT, Hoflack J, Abbott DW.

J Biol Chem. 2014 Oct 24;289(43):29651-64. doi: 10.1074/jbc.M114.591388. Epub 2014 Sep 11.

27.

Immunosuppressive monocytes: possible homeostatic mechanism to restrain chronic intestinal inflammation.

Kurmaeva E, Bhattacharya D, Goodman W, Omenetti S, Merendino A, Berney S, Pizarro T, Ostanin DV.

J Leukoc Biol. 2014 Sep;96(3):377-89. doi: 10.1189/jlb.3HI0613-340RR. Epub 2014 Apr 2.

28.

Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn's-like ileitis.

Goodman WA, Garg RR, Reuter BK, Mattioli B, Rissman EF, Pizarro TT.

Mucosal Immunol. 2014 Sep;7(5):1255-65. doi: 10.1038/mi.2014.15. Epub 2014 Mar 12.

29.

Chilean complementary feeding program reduces anemia and improves iron status in children aged 11 to 18 months.

Brito A, Olivares M, Pizarro T, Rodríguez L, Hertrampf E.

Food Nutr Bull. 2013 Dec;34(4):378-85.

PMID:
24605687
30.

Administration of reconstituted polyphenol oil bodies efficiently suppresses dendritic cell inflammatory pathways and acute intestinal inflammation.

Cavalcanti E, Vadrucci E, Delvecchio FR, Addabbo F, Bettini S, Liou R, Monsurrò V, Huang AY, Pizarro TT, Santino A, Chieppa M.

PLoS One. 2014 Feb 18;9(2):e88898. doi: 10.1371/journal.pone.0088898. eCollection 2014.

31.

Flexible colonoscopy in mice to evaluate the severity of colitis and colorectal tumors using a validated endoscopic scoring system.

Kodani T, Rodriguez-Palacios A, Corridoni D, Lopetuso L, Di Martino L, Marks B, Pizarro J, Pizarro T, Chak A, Cominelli F.

J Vis Exp. 2013 Oct 16;(80):e50843. doi: 10.3791/50843.

32.

Regulatory cell populations in the intestinal mucosa.

Goodman WA, Pizarro TT.

Curr Opin Gastroenterol. 2013 Nov;29(6):614-20. doi: 10.1097/MOG.0b013e328365d30f. Review.

PMID:
24100716
33.

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16999-7004. doi: 10.1073/pnas.1311657110. Epub 2013 Sep 30.

34.

Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics.

Pastorelli L, De Salvo C, Mercado JR, Vecchi M, Pizarro TT.

Front Immunol. 2013 Sep 17;4:280. doi: 10.3389/fimmu.2013.00280. Review.

35.

Intestinal-specific TNFα overexpression induces Crohn's-like ileitis in mice.

Bamias G, Dahman MI, Arseneau KO, Guanzon M, Gruska D, Pizarro TT, Cominelli F.

PLoS One. 2013 Aug 20;8(8):e72594. doi: 10.1371/journal.pone.0072594. eCollection 2013.

36.

Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.

Lopetuso LR, Chowdhry S, Pizarro TT.

Front Immunol. 2013 Jul 9;4:181. doi: 10.3389/fimmu.2013.00181. eCollection 2013.

37.

The role of IL-33 in gut mucosal inflammation.

Pastorelli L, De Salvo C, Vecchi M, Pizarro TT.

Mediators Inflamm. 2013;2013:608187. doi: 10.1155/2013/608187. Epub 2013 May 23. Review.

38.

[Willingness to pay for human papillomavirus vaccine in Metropolitan Santiago, Chile].

Cerda AA, Garcia LY, Gaete FI, Pizarro TH.

Rev Med Chil. 2013 Feb;141(2):167-72. doi: 10.4067/S0034-98872013000200004. Spanish.

39.

Associations between genetic polymorphisms in IL-33, IL1R1 and risk for inflammatory bowel disease.

Latiano A, Palmieri O, Pastorelli L, Vecchi M, Pizarro TT, Bossa F, Merla G, Augello B, Latiano T, Corritore G, Settesoldi A, Valvano MR, D'Incà R, Stronati L, Annese V, Andriulli A.

PLoS One. 2013 Apr 25;8(4):e62144. doi: 10.1371/journal.pone.0062144. Print 2013.

40.

Challenges in IBD research: update on progress and prioritization of the CCFA's research agenda.

Denson LA, Long MD, McGovern DP, Kugathasan S, Wu GD, Young VB, Pizarro TT, de Zoeten EF, Stappenbeck TS, Plevy SE, Abraham C, Nusrat A, Jobin C, McCole DF, Siegel CA, Higgins PD, Herfarth HH, Hyams J, Sandborn WJ, Loftus EV Jr, Kappelman MD, Lewis JD, Parkos CA, Sartor RB; Challenges Workgroup.

Inflamm Bowel Dis. 2013 Mar-Apr;19(4):677-82. doi: 10.1097/MIB.0b013e31828134b3. No abstract available.

41.

Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease.

Tlaxca JL, Rychak JJ, Ernst PB, Konkalmatt PR, Shevchenko TI, Pizarro TT, Rivera-Nieves J, Klibanov AL, Lawrence MB.

J Control Release. 2013 Feb 10;165(3):216-25. doi: 10.1016/j.jconrel.2012.10.021. Epub 2012 Nov 8. Erratum in: J Control Release. 2014 Jan 10;173:10. Pizzaro, Theresa T [corrected to Pizarro, Theresa T].

42.

Emerging role of the interleukin (IL)-33/ST2 axis in gut mucosal wound healing and fibrosis.

Lopetuso LR, Scaldaferri F, Pizarro TT.

Fibrogenesis Tissue Repair. 2012 Oct 14;5(1):18. doi: 10.1186/1755-1536-5-18.

43.

Probiotic bacteria regulate intestinal epithelial permeability in experimental ileitis by a TNF-dependent mechanism.

Corridoni D, Pastorelli L, Mattioli B, Locovei S, Ishikawa D, Arseneau KO, Chieppa M, Cominelli F, Pizarro TT.

PLoS One. 2012;7(7):e42067. doi: 10.1371/journal.pone.0042067. Epub 2012 Jul 25.

44.

New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation.

Bamias G, Corridoni D, Pizarro TT, Cominelli F.

Cytokine. 2012 Sep;59(3):451-9. doi: 10.1016/j.cyto.2012.06.014. Epub 2012 Jul 12. Review.

45.

Tregs are dysfunctional in vivo in a spontaneous murine model of Crohn's disease.

Ishikawa D, Okazawa A, Corridoni D, Jia LG, Wang XM, Guanzon M, Xin W, Arseneau KO, Pizarro TT, Cominelli F.

Mucosal Immunol. 2013 Mar;6(2):267-75. doi: 10.1038/mi.2012.67. Epub 2012 Jul 11.

46.

Novel cytokine signaling pathways in inflammatory bowel disease: insight into the dichotomous functions of IL-33 during chronic intestinal inflammation.

Pastorelli L, De Salvo C, Cominelli MA, Vecchi M, Pizarro TT.

Therap Adv Gastroenterol. 2011 Sep;4(5):311-23. doi: 10.1177/1756283X11410770.

47.

Spontaneous, immune-mediated gastric inflammation in SAMP1/YitFc mice, a model of Crohn's-like gastritis.

Reuter BK, Pastorelli L, Brogi M, Garg RR, McBride JA, Rowlett RM, Arrieta MC, Wang XM, Keller EJ, Feldman SH, Mize JR, Cominelli F, Meddings JB, Pizarro TT.

Gastroenterology. 2011 Nov;141(5):1709-19. doi: 10.1053/j.gastro.2011.06.041. Epub 2011 Jun 23.

48.

SAMP1/YitFc mouse strain: a spontaneous model of Crohn's disease-like ileitis.

Pizarro TT, Pastorelli L, Bamias G, Garg RR, Reuter BK, Mercado JR, Chieppa M, Arseneau KO, Ley K, Cominelli F.

Inflamm Bowel Dis. 2011 Dec;17(12):2566-84. doi: 10.1002/ibd.21638. Epub 2011 May 6. Review.

49.

IL-1 family nomenclature.

Dinarello C, Arend W, Sims J, Smith D, Blumberg H, O'Neill L, Goldbach-Mansky R, Pizarro T, Hoffman H, Bufler P, Nold M, Ghezzi P, Mantovani A, Garlanda C, Boraschi D, Rubartelli A, Netea M, van der Meer J, Joosten L, Mandrup-Poulsen T, Donath M, Lewis E, Pfeilschifter J, Martin M, Kracht M, Muehl H, Novick D, Lukic M, Conti B, Solinger A, Kelk P, van de Veerdonk F, Gabel C.

Nat Immunol. 2010 Nov;11(11):973. doi: 10.1038/ni1110-973. No abstract available. Erratum in: Nat Immunol. 2011 Mar;12(3):271. Peyman, Kelk [corrected to Kelk, Peyman].

50.

Beta7 integrin deficiency suppresses B cell homing and attenuates chronic ileitis in SAMP1/YitFc mice.

Gorfu G, Rivera-Nieves J, Hoang S, Abbott DW, Arbenz-Smith K, Azar DW, Pizarro TT, Cominelli F, McDuffie M, Ley K.

J Immunol. 2010 Nov 1;185(9):5561-8. doi: 10.4049/jimmunol.0903938. Epub 2010 Oct 6.

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