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Items: 1 to 50 of 57

1.

A higher degree of expression of DNA methyl transferase 1 in cervical cancer is associated with poor survival outcome.

Piyathilake CJ, Badiga S, Borak SG, Weragoda J, Bae S, Matthews R, Bell WC, Partridge EE.

Int J Womens Health. 2017 Jun 8;9:413-420. doi: 10.2147/IJWH.S133441. eCollection 2017.

2.

Urinary Microbiota Associated with Preterm Birth: Results from the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) Study.

Ollberding NJ, Völgyi E, Macaluso M, Kumar R, Morrow C, Tylavsky FA, Piyathilake CJ.

PLoS One. 2016 Sep 9;11(9):e0162302. doi: 10.1371/journal.pone.0162302. eCollection 2016.

3.

Expression of p16INK4A in cervical precancerous lesions that is unlikely to be preventable by human papillomavirus vaccines.

Badiga S, Chambers MM, Huh W, Eltoum IA, Piyathilake CJ.

Cancer. 2016 Dec 1;122(23):3615-3623. doi: 10.1002/cncr.30229. Epub 2016 Aug 1. Erratum in: Cancer. 2017 Aug 15;123(16):3198.

4.

Accuracy of urinary human papillomavirus testing for the presence of cervical human papillomaviruses and higher grades of cervical intraepithelial neoplasia.

Piyathilake CJ, Badiga S, Chambers MM, Brill IK, Matthews R, Partridge EE.

Cancer. 2016 Sep 15;122(18):2836-44. doi: 10.1002/cncr.30123. Epub 2016 May 31.

5.

Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification Era.

Badiga S, Siddiqui NR, Macaluso M, Johanning GL, Piyathilake CJ.

Nutr Cancer. 2016;68(3):446-55. doi: 10.1080/01635581.2016.1152388. Epub 2016 Mar 23.

PMID:
27008272
6.

Cervical Microbiota Associated with Higher Grade Cervical Intraepithelial Neoplasia in Women Infected with High-Risk Human Papillomaviruses.

Piyathilake CJ, Ollberding NJ, Kumar R, Macaluso M, Alvarez RD, Morrow CD.

Cancer Prev Res (Phila). 2016 May;9(5):357-66. doi: 10.1158/1940-6207.CAPR-15-0350. Epub 2016 Mar 2.

7.

A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification era.

Badiga S, Johanning GL, Macaluso M, Azuero A, Chambers MM, Siddiqui NR, Piyathilake CJ.

PLoS One. 2014 Oct 10;9(10):e110093. doi: 10.1371/journal.pone.0110093. eCollection 2014.

8.

Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infection.

Sudenga SL, Shrestha S, Macaluso M, Partridge EE, Johanning GL, Piyathilake CJ.

Gynecol Oncol. 2014 Dec;135(3):560-4. doi: 10.1016/j.ygyno.2014.09.015. Epub 2014 Oct 1.

9.

Folate and vitamin B12 may play a critical role in lowering the HPV 16 methylation-associated risk of developing higher grades of CIN.

Piyathilake CJ, Macaluso M, Chambers MM, Badiga S, Siddiqui NR, Bell WC, Edberg JC, Partridge EE, Alvarez RD, Johanning GL.

Cancer Prev Res (Phila). 2014 Nov;7(11):1128-37. doi: 10.1158/1940-6207.CAPR-14-0143. Epub 2014 Aug 21.

10.

Excess body weight during pregnancy and offspring obesity: potential mechanisms.

Paliy O, Piyathilake CJ, Kozyrskyj A, Celep G, Marotta F, Rastmanesh R.

Nutrition. 2014 Mar;30(3):245-51. doi: 10.1016/j.nut.2013.05.011. Epub 2013 Oct 6. Review.

PMID:
24103493
11.

Mild obesity, physical activity, calorie intake, and the risks of cervical intraepithelial neoplasia and cervical cancer.

Lee JK, So KA, Piyathilake CJ, Kim MK.

PLoS One. 2013 Jun 12;8(6):e66555. doi: 10.1371/journal.pone.0066555. Print 2013.

12.

Intake and blood concentrations of folate and their association with health-related behaviors in Korean college students.

Jang HB, Han YH, Piyathilake CJ, Kim H, Hyun T.

Nutr Res Pract. 2013 Jun;7(3):216-23. doi: 10.4162/nrp.2013.7.3.216. Epub 2013 Jun 3.

13.

A lower degree of PBMC L1 methylation is associated with excess body weight and higher HOMA-IR in the presence of lower concentrations of plasma folate.

Piyathilake CJ, Badiga S, Alvarez RD, Partridge EE, Johanning GL.

PLoS One. 2013;8(1):e54544. doi: 10.1371/journal.pone.0054544. Epub 2013 Jan 24.

14.

Triple Negative Breast Cancer - An Overview.

Aysola K, Desai A, Welch C, Xu J, Qin Y, Reddy V, Matthews R, Owens C, Okoli J, Beech DJ, Piyathilake CJ, Reddy SP, Rao VN.

Hereditary Genet. 2013;2013(Suppl 2). pii: 001.

15.

A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasia.

Piyathilake CJ, Badiga S, Kabagambe EK, Azuero A, Alvarez RD, Johanning GL, Partridge EE.

Cancer Prev Res (Phila). 2012 Mar;5(3):385-92. doi: 10.1158/1940-6207.CAPR-11-0387. Epub 2012 Jan 18.

16.

A Simple Distribution-Free Algorithm for Generating Simulated High-Dimensional Correlated Data with an Autoregressive Structure.

Azuero A, Redden DT, Tiwari HK, Asmellash SG, Piyathilake CJ.

Commun Stat Simul Comput. 2012 Jan 1;41(1):89-98.

17.

Aflatoxin levels, plasma vitamins A and E concentrations, and their association with HIV and hepatitis B virus infections in Ghanaians: a cross-sectional study.

Obuseh FA, Jolly PE, Kulczycki A, Ehiri J, Waterbor J, Desmond RA, Preko PO, Jiang Y, Piyathilake CJ.

J Int AIDS Soc. 2011 Nov 11;14:53. doi: 10.1186/1758-2652-14-53.

18.

Aflatoxin B1 albumin adducts in plasma and aflatoxin M1 in urine are associated with plasma concentrations of vitamins A and E.

Obuseh FA, Jolly PE, Jiang Y, Shuaib FM, Waterbor J, Ellis WO, Piyathilake CJ, Desmond RA, Afriyie-Gyawu E, Phillips TD.

Int J Vitam Nutr Res. 2010 Dec;80(6):355-68. doi: 10.1024/0300-9831/a000021.

19.

Usefulness of serum mass spectrometry to identify women diagnosed with higher grades of cervical intraepithelial neoplasia may differ by race.

Matthews R, Azuero A, Asmellash S, Brewster E, Partridge EE, Piyathilake CJ.

Int J Womens Health. 2011;3:185-92. doi: 10.2147/IJWH.S20685. Epub 2011 Jul 12.

20.

A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia.

Piyathilake CJ, Macaluso M, Alvarez RD, Chen M, Badiga S, Siddiqui NR, Edberg JC, Partridge EE, Johanning GL.

Nutrition. 2011 May;27(5):513-9. doi: 10.1016/j.nut.2010.08.018.

21.

Indian women with higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs).

Piyathilake CJ, Badiga S, Paul P, Vijayaraghavan K, Vedantham H, Sudula M, Sowjanya P, Ramakrishna G, Shah KV, Partridge EE, Gravitt PE.

Int J Womens Health. 2010 Aug 9;2:7-12.

22.
23.

A higher degree of methylation of the HPV 16 E6 gene is associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasia.

Piyathilake CJ, Macaluso M, Alvarez RD, Chen M, Badiga S, Edberg JC, Partridge EE, Johanning GL.

Cancer. 2011 Mar 1;117(5):957-63. doi: 10.1002/cncr.25511. Epub 2010 Oct 13.

24.

Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification era.

Piyathilake CJ, Macaluso M, Alvarez RD, Bell WC, Heimburger DC, Partridge EE.

Cancer Prev Res (Phila). 2009 Jul;2(7):658-64. doi: 10.1158/1940-6207.CAPR-08-0175. Epub 2009 Jun 19. Erratum in: Cancer Prev Res (Phila Pa).2009 Sep;2(9):842.

25.

Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients.

Wang-Johanning F, Radvanyi L, Rycaj K, Plummer JB, Yan P, Sastry KJ, Piyathilake CJ, Hunt KK, Johanning GL.

Cancer Res. 2008 Jul 15;68(14):5869-77. doi: 10.1158/0008-5472.CAN-07-6838.

26.

Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervix.

Piyathilake CJ, Celedonio JE, Macaluso M, Bell WC, Azrad M, Grizzle WE.

Nutrition. 2008 Jan;24(1):94-9.

27.

Update on micronutrients and cervical dysplasia.

Piyathilake CJ.

Ethn Dis. 2007 Spring;17(2 Suppl 2):S2-14-7. Review.

PMID:
17684808
28.

Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status.

Piyathilake CJ, Azrad M, Macaluso M, Johanning GL, Cornwell PE, Partridge EE, Heimburger DC.

Nutrition. 2007 Mar;23(3):229-35. Epub 2007 Feb 14.

29.

Lower red blood cell folate enhances the HPV-16-associated risk of cervical intraepithelial neoplasia.

Piyathilake CJ, Macaluso M, Brill I, Heimburger DC, Partridge EE.

Nutrition. 2007 Mar;23(3):203-10. Epub 2007 Feb 1.

PMID:
17276035
30.

Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis.

Piyathilake CJ, Azrad M, Jhala D, Macaluso M, Kabagambe EK, Brill I, Niveleau A, Jhala N, Grizzle WE.

Cancer Biomark. 2006;2(6):259-66.

PMID:
17264397
31.

A practical approach to red blood cell folate analysis.

Piyathilake CJ, Robinson CB, Cornwell P.

Anal Chem Insights. 2007 Nov 14;2:107-10.

32.

Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (cin) 1 and 3.

Piyathilake CJ, Oelschlager DK, Meleth S, Partridge EE, Grizzle WE.

Cancer Inform. 2007 Feb 27;2:345-9.

33.

Intrinsic cisplatin resistance in lung and ovarian cancer cells propagating in medium acutely depleted of folate.

Whiteside MA, Piyathilake CJ, Bushell TM, Johanning GL.

Nutr Cancer. 2006;54(2):274-84.

PMID:
16898872
34.

Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.

Owsley C, McGwin G, Jackson GR, Heimburger DC, Piyathilake CJ, Klein R, White MF, Kallies K.

Invest Ophthalmol Vis Sci. 2006 Apr;47(4):1310-8.

PMID:
16565362
35.

Patterns of global DNA and histone methylation appear to be similar in normal, dysplastic and neoplastic oral epithelium of humans.

Piyathilake CJ, Bell WC, Jones J, Henao OL, Heimburger DC, Niveleau A, Grizzle WE.

Dis Markers. 2005;21(3):147-51.

36.

Pattern of nonspecific (or global) DNA methylation in oral carcinogenesis.

Piyathilake CJ, Bell WC, Jones J, Henao OL, Heimburger DC, Niveleau A, Grizzle WE.

Head Neck. 2005 Dec;27(12):1061-7.

37.

Folate is associated with the natural history of high-risk human papillomaviruses.

Piyathilake CJ, Henao OL, Macaluso M, Cornwell PE, Meleth S, Heimburger DC, Partridge EE.

Cancer Res. 2004 Dec 1;64(23):8788-93.

38.

Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3.

Henao OL, Piyathilake CJ, Waterbor JW, Funkhouser E, Johanning GL, Heimburger DC, Partridge EE.

Int J Cancer. 2005 Mar 1;113(6):991-7.

40.

Effect of folic acid fortification of foods on folate intake in female smokers with cervical dysplasia.

Shikany JM, Heimburger DC, Piyathilake CJ, Desmond RA, Greene PG.

Nutrition. 2004 May;20(5):409-14.

PMID:
15105026
41.

Retinoids and epigenetic silencing in cancer.

Johanning GL, Piyathilake CJ.

Nutr Rev. 2003 Aug;61(8):284-9. Review.

PMID:
13677591
42.

Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States).

Piyathilake CJ, Henao O, Frost AR, Macaluso M, Bell WC, Johanning GL, Heimburger DC, Niveleau A, Grizzle WE.

Cancer Causes Control. 2003 Feb;14(1):37-42.

PMID:
12708723
43.

Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers.

Piyathilake CJ, Frost AR, Manne U, Weiss H, Heimburger DC, Grizzle WE.

Chest. 2003 Jan;123(1):181-6.

PMID:
12527620
44.

DNA methylation and diet in cancer.

Johanning GL, Heimburger DC, Piyathilake CJ.

J Nutr. 2002 Dec;132(12):3814S-3818S.

PMID:
12468630
45.

The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavity.

Piyathilake CJ, Bell WC, Oelschlager DK, Heimburger DC, Grizzle WE.

Head Neck. 2002 Sep;24(9):859-67.

PMID:
12211050
46.

Cellular vitamins, DNA methylation and cancer risk.

Piyathilake CJ, Johanning GL.

J Nutr. 2002 Aug;132(8 Suppl):2340S-2344S. doi: 10.1093/jn/132.8.2340S.

PMID:
12163689
47.

Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.

Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.

Clin Cancer Res. 2002 Mar;8(3):734-44.

48.

Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.

Piyathilake CJ, Frost AR, Bell WC, Oelschlager D, Weiss H, Johanning GL, Niveleau A, Heimburger DC, Grizzle WE.

Hum Pathol. 2001 Aug;32(8):856-62.

PMID:
11521231
49.

Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.

Piyathilake CJ, Johanning GL, Frost AR, Whiteside MA, Manne U, Grizzle WE, Heimburger DC, Niveleau A.

Biotech Histochem. 2000 Nov;75(6):251-8.

PMID:
11131565
50.

The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung.

Piyathilake CJ, Frost AR, Manne U, Bell WC, Weiss H, Heimburger DC, Grizzle WE.

Hum Pathol. 2000 Sep;31(9):1068-73.

PMID:
11014573

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