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Items: 1 to 50 of 121

1.

Anti-GluA3 antibodies in frontotemporal dementia: effects on glutamatergic neurotransmission and synaptic failure.

Palese F, Bonomi E, Nuzzo T, Benussi A, Mellone M, Zianni E, Cisani F, Casamassa A, Alberici A, Scheggia D, Padovani A, Marcello E, Di Luca M, Pittaluga A, Usiello A, Borroni B, Gardoni F.

Neurobiol Aging. 2020 Feb;86:143-155. doi: 10.1016/j.neurobiolaging.2019.10.015. Epub 2019 Nov 1.

PMID:
31784278
2.

Presynaptic Release-Regulating Metabotropic Glutamate Receptors: An Update.

Olivero G, Vergassola M, Cisani F, Rogger A, Pittaluga A.

Curr Neuropharmacol. 2019 Nov 26. doi: 10.2174/1570159X17666191127112339. [Epub ahead of print]

PMID:
31775600
4.

Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review.

Alfei S, Turrini F, Catena S, Zunin P, Grilli M, Pittaluga AM, Boggia R.

Eur J Med Chem. 2019 Dec 1;183:111724. doi: 10.1016/j.ejmech.2019.111724. Epub 2019 Sep 20. Review.

PMID:
31563012
5.

Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and Cognition.

Franchini L, Stanic J, Ponzoni L, Mellone M, Carrano N, Musardo S, Zianni E, Olivero G, Marcello E, Pittaluga A, Sala M, Bellone C, Racca C, Di Luca M, Gardoni F.

iScience. 2019 Sep 27;19:927-939. doi: 10.1016/j.isci.2019.08.036. Epub 2019 Aug 27.

6.

Acute Functional Adaptations in Isolated Presynaptic Terminals Unveil Synaptosomal Learning and Memory.

Pittaluga A.

Int J Mol Sci. 2019 Jul 25;20(15). pii: E3641. doi: 10.3390/ijms20153641. Review.

7.

The selective disruption of presynaptic JNK2/STX1a interaction reduces NMDA receptor-dependent glutamate release.

Marcelli S, Iannuzzi F, Ficulle E, Mango D, Pieraccini S, Pellegrino S, Corbo M, Sironi M, Pittaluga A, Nisticò R, Feligioni M.

Sci Rep. 2019 May 9;9(1):7146. doi: 10.1038/s41598-019-43709-2.

8.

Prolonged activation of CXCR4 hampers the release-regulating activity of presynaptic NMDA receptors in rat hippocampal synaptosomes.

Olivero G, Cisani F, Vergassola M, Pittaluga A.

Neurochem Int. 2019 Jun;126:59-63. doi: 10.1016/j.neuint.2019.03.003. Epub 2019 Mar 8.

PMID:
30858017
9.

Immuno-Pharmacological Characterization of Presynaptic GluN3A-Containing NMDA Autoreceptors: Relevance to Anti-NMDA Receptor Autoimmune Diseases.

Olivero G, Vergassola M, Cisani F, Usai C, Pittaluga A.

Mol Neurobiol. 2019 Sep;56(9):6142-6155. doi: 10.1007/s12035-019-1511-8. Epub 2019 Feb 7.

PMID:
30734226
10.

An innovative green extraction and re-use strategy to valorize food supplement by-products: Castanea sativa bud preparations as case study.

Turrini F, Donno D, Boggia R, Beccaro GL, Zunin P, Leardi R, Pittaluga AM.

Food Res Int. 2019 Jan;115:276-282. doi: 10.1016/j.foodres.2018.12.018. Epub 2018 Dec 17.

PMID:
30599942
11.

Presynaptic mGlu1 Receptors Control GABAB Receptors in an Antagonist-Like Manner in Mouse Cortical GABAergic and Glutamatergic Nerve Endings.

Vergassola M, Olivero G, Cisani F, Usai C, Bossi S, Puliti A, Pittaluga A.

Front Mol Neurosci. 2018 Sep 18;11:324. doi: 10.3389/fnmol.2018.00324. eCollection 2018.

12.

The reduction in glutamate release is predictive of cognitive and emotional alterations that are corrected by the positive modulator of AMPA receptors S 47445 in perinatal stressed rats.

Morley-Fletcher S, Zuena AR, Mairesse J, Gatta E, Van Camp G, Bouwalerh H, Riozzi B, Battaglia G, Pittaluga A, Olivero G, Mocaer E, Bretin S, Nicoletti F, Maccari S.

Neuropharmacology. 2018 Jun;135:284-296. doi: 10.1016/j.neuropharm.2018.03.018. Epub 2018 Mar 23.

PMID:
29578034
13.

5-HT2A-mGlu2/3 receptor complex in rat spinal cord glutamatergic nerve endings: A 5-HT2A to mGlu2/3 signalling to amplify presynaptic mechanism of auto-control of glutamate exocytosis.

Olivero G, Grilli M, Vergassola M, Bonfiglio T, Padolecchia C, Garrone B, Di Giorgio FP, Tongiani S, Usai C, Marchi M, Pittaluga A.

Neuropharmacology. 2018 May 1;133:429-439. doi: 10.1016/j.neuropharm.2018.02.030. Epub 2018 Feb 27.

PMID:
29499271
14.

Environmental Training and Synaptic Functions in Young and Old Brain: A Presynaptic Perspective.

Bonfiglio T, Vergassola M, Olivero G, Pittaluga A.

Curr Med Chem. 2019;26(20):3670-3684. doi: 10.2174/0929867325666180228170450. Review.

PMID:
29493441
15.

Environmental training is beneficial to clinical symptoms and cortical presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis.

Bonfiglio T, Olivero G, Vergassola M, Di Cesare Mannelli L, Pacini A, Iannuzzi F, Summa M, Bertorelli R, Feligioni M, Ghelardini C, Pittaluga A.

Neuropharmacology. 2019 Feb;145(Pt A):75-86. doi: 10.1016/j.neuropharm.2018.01.026. Epub 2018 Feb 2.

PMID:
29402503
16.

Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies.

Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Maria Sciacca MF, Sinopoli A, Milardi D, Pappalardo G, Marco S, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G.

Oncotarget. 2017 Apr 22;8(39):64745-64778. doi: 10.18632/oncotarget.17371. eCollection 2017 Sep 12.

17.

Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.

Bossi S, Musante I, Bonfiglio T, Bonifacino T, Emionite L, Cerminara M, Cervetto C, Marcoli M, Bonanno G, Ravazzolo R, Pittaluga A, Puliti A.

Neurobiol Dis. 2018 Jan;109(Pt A):44-53. doi: 10.1016/j.nbd.2017.10.001. Epub 2017 Oct 2.

PMID:
28982591
18.

Immuno-pharmacological characterization of group II metabotropic glutamate receptors controlling glutamate exocytosis in mouse cortex and spinal cord.

Olivero G, Bonfiglio T, Vergassola M, Usai C, Riozzi B, Battaglia G, Nicoletti F, Pittaluga A.

Br J Pharmacol. 2017 Dec;174(24):4785-4796. doi: 10.1111/bph.14061. Epub 2017 Oct 29.

19.

CCL5-Glutamate Cross-Talk in Astrocyte-Neuron Communication in Multiple Sclerosis.

Pittaluga A.

Front Immunol. 2017 Sep 4;8:1079. doi: 10.3389/fimmu.2017.01079. eCollection 2017. Review.

20.

Prophylactic versus Therapeutic Fingolimod: Restoration of Presynaptic Defects in Mice Suffering from Experimental Autoimmune Encephalomyelitis.

Bonfiglio T, Olivero G, Merega E, Di Prisco S, Padolecchia C, Grilli M, Milanese M, Di Cesare Mannelli L, Ghelardini C, Bonanno G, Marchi M, Pittaluga A.

PLoS One. 2017 Jan 26;12(1):e0170825. doi: 10.1371/journal.pone.0170825. eCollection 2017.

21.

Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner.

Reynaert ML, Marrocco J, Mairesse J, Lionetto L, Simmaco M, Deruyter L, Allorge D, Moles A, Pittaluga A, Maccari S, Morley-Fletcher S, Van Camp G, Nicoletti F.

Addict Biol. 2016 Nov;21(6):1072-1085. doi: 10.1111/adb.12270. Epub 2015 May 26.

PMID:
26011513
22.

Presynaptic Release-Regulating mGlu1 Receptors in Central Nervous System.

Pittaluga A.

Front Pharmacol. 2016 Aug 31;7:295. doi: 10.3389/fphar.2016.00295. eCollection 2016. Review.

23.

Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats.

Zamberletti E, Gabaglio M, Grilli M, Prini P, Catanese A, Pittaluga A, Marchi M, Rubino T, Parolaro D.

Pharmacol Res. 2016 Sep;111:459-470. doi: 10.1016/j.phrs.2016.07.008. Epub 2016 Jul 12.

PMID:
27422357
24.

CXCR4 and NMDA Receptors Are Functionally Coupled in Rat Hippocampal Noradrenergic and Glutamatergic Nerve Endings.

Di Prisco S, Olivero G, Merega E, Bonfiglio T, Marchi M, Pittaluga A.

J Neuroimmune Pharmacol. 2016 Dec;11(4):645-656. Epub 2016 May 5.

PMID:
27147258
25.

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.

Brindisi M, Maramai S, Gemma S, Brogi S, Grillo A, Di Cesare Mannelli L, Gabellieri E, Lamponi S, Saponara S, Gorelli B, Tedesco D, Bonfiglio T, Landry C, Jung KM, Armirotti A, Luongo L, Ligresti A, Piscitelli F, Bertucci C, Dehouck MP, Campiani G, Maione S, Ghelardini C, Pittaluga A, Piomelli D, Di Marzo V, Butini S.

J Med Chem. 2016 Mar 24;59(6):2612-32. doi: 10.1021/acs.jmedchem.5b01812. Epub 2016 Mar 7.

26.

Presynaptic, release-regulating mGlu2 -preferring and mGlu3 -preferring autoreceptors in CNS: pharmacological profiles and functional roles in demyelinating disease.

Di Prisco S, Merega E, Bonfiglio T, Olivero G, Cervetto C, Grilli M, Usai C, Marchi M, Pittaluga A.

Br J Pharmacol. 2016 May;173(9):1465-77. doi: 10.1111/bph.13442. Epub 2016 Mar 3.

27.

Inhibition of hippocampal plasticity in rats performing contrafreeloading for water under repeated administrations of pramipexole.

Schepisi C, Pignataro A, Doronzio SS, Piccinin S, Ferraina C, Di Prisco S, Feligioni M, Pittaluga A, Mercuri NB, Ammassari-Teule M, Nisticò R, Nencini P.

Psychopharmacology (Berl). 2016 Feb;233(4):727-37. doi: 10.1007/s00213-015-4150-4. Epub 2015 Nov 17.

PMID:
26572895
28.

Activation of presynaptic oxytocin receptors enhances glutamate release in the ventral hippocampus of prenatally restraint stressed rats.

Mairesse J, Gatta E, Reynaert ML, Marrocco J, Morley-Fletcher S, Soichot M, Deruyter L, Camp GV, Bouwalerh H, Fagioli F, Pittaluga A, Allorge D, Nicoletti F, Maccari S.

Psychoneuroendocrinology. 2015 Dec;62:36-46. doi: 10.1016/j.psyneuen.2015.07.005. Epub 2015 Jul 18.

PMID:
26231445
29.

Antibody/receptor protein immunocomplex in human and mouse cortical nerve endings amplifies complement-induced glutamate release.

Merega E, Prisco SD, Severi P, Kalfas F, Pittaluga A.

Neurosci Lett. 2015 Jul 23;600:50-5. doi: 10.1016/j.neulet.2015.06.001. Epub 2015 Jun 3.

PMID:
26049008
30.

Nicotinic modulation of glutamate receptor function at nerve terminal level: a fine-tuning of synaptic signals.

Marchi M, Grilli M, Pittaluga AM.

Front Pharmacol. 2015 Apr 29;6:89. doi: 10.3389/fphar.2015.00089. eCollection 2015. Review.

31.

Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate release.

Nisticò R, Florenzano F, Mango D, Ferraina C, Grilli M, Di Prisco S, Nobili A, Saccucci S, D'Amelio M, Morbin M, Marchi M, Mercuri NB, Davis RJ, Pittaluga A, Feligioni M.

Sci Rep. 2015 Mar 12;5:9035. doi: 10.1038/srep09035.

32.

Isolation of hydroxyoctaprenyl-1',4'-hydroquinone, a new octaprenylhydroquinone from the marine sponge Sarcotragus spinosulus and evaluation of its pharmacological activity on acetylcholine and glutamate release in the rat central nervous system.

Bisio A, Fedele E, Pittaluga A, Olivero G, Grilli M, Chen J, Mele G, Malafronte N, De Tommasi N, Leddae F, Manconi R, Pronzato R, Marchi M.

Nat Prod Commun. 2014 Nov;9(11):1581-4.

PMID:
25532286
33.

Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbens.

Zappettini S, Grilli M, Olivero G, Chen J, Padolecchia C, Pittaluga A, Tomé AR, Cunha RA, Marchi M.

Front Cell Neurosci. 2014 Oct 16;8:332. doi: 10.3389/fncel.2014.00332. eCollection 2014.

34.

Functional adaptation of presynaptic chemokine receptors in EAE mouse central nervous system.

Di Prisco S, Merega E, Pittaluga A.

Synapse. 2014 Nov;68(11):529-35. doi: 10.1002/syn.21774. Epub 2014 Aug 19.

PMID:
25092801
35.

Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740.

Orlando R, Borro M, Motolese M, Molinaro G, Scaccianoce S, Caruso A, di Nuzzo L, Caraci F, Matrisciano F, Pittaluga A, Mairesse J, Simmaco M, Nisticò R, Monn JA, Nicoletti F.

Neuropharmacology. 2014 Nov;86:133-44. doi: 10.1016/j.neuropharm.2014.07.009. Epub 2014 Jul 22.

PMID:
25063582
36.

Acute desipramine restores presynaptic cortical defects in murine experimental autoimmune encephalomyelitis by suppressing central CCL5 overproduction.

Di Prisco S, Merega E, Lanfranco M, Casazza S, Uccelli A, Pittaluga A.

Br J Pharmacol. 2014 May;171(9):2457-67. doi: 10.1111/bph.12631.

37.

The effects of antidepressant treatment in prenatally stressed rats support the glutamatergic hypothesis of stress-related disorders.

Marrocco J, Reynaert ML, Gatta E, Gabriel C, Mocaër E, Di Prisco S, Merega E, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S, Mairesse J.

J Neurosci. 2014 Feb 5;34(6):2015-24. doi: 10.1523/JNEUROSCI.4131-13.2014.

38.

Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.

Fariello RG, Ghelardini C, Di Cesare Mannelli L, Bonanno G, Pittaluga A, Milanese M, Misiano P, Farina C.

Neuropharmacology. 2014 Jun;81:85-94. doi: 10.1016/j.neuropharm.2014.01.029. Epub 2014 Jan 31.

PMID:
24486381
39.

Complement selectively elicits glutamate release from nerve endings in different regions of mammal central nervous system.

Merega E, Di Prisco S, Lanfranco M, Severi P, Pittaluga A.

J Neurochem. 2014 May;129(3):473-83. doi: 10.1111/jnc.12650. Epub 2014 Jan 25.

40.

Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens.

Salamone A, Zappettini S, Grilli M, Olivero G, Agostinho P, Tomé AR, Chen J, Pittaluga A, Cunha RA, Marchi M.

Neuropharmacology. 2014 Apr;79:488-97. doi: 10.1016/j.neuropharm.2013.12.014. Epub 2013 Dec 25.

PMID:
24373903
41.

Pharmacological characterization of NMDA-like receptors in the single-celled organism Paramecium primaurelia.

Ramoino P, Candiani S, Pittaluga AM, Usai C, Gallus L, Ferrando S, Milanese M, Faimali M, Bonanno G.

J Exp Biol. 2014 Feb 1;217(Pt 3):463-71. doi: 10.1242/jeb.093914. Epub 2013 Oct 18.

42.

CCL5-glutamate interaction in central nervous system: Early and acute presynaptic defects in EAE mice.

Di Prisco S, Merega E, Milanese M, Summa M, Casazza S, Raffaghello L, Pistoia V, Uccelli A, Pittaluga A.

Neuropharmacology. 2013 Dec;75:337-46. doi: 10.1016/j.neuropharm.2013.07.037. Epub 2013 Aug 16.

PMID:
23958452
43.

Dangerous liaisons between beta-amyloid and cholinergic neurotransmission.

Govoni S, Mura E, Preda S, Racchi M, Lanni C, Grilli M, Zappettini S, Salamone A, Olivero G, Pittaluga A, Marchi M.

Curr Pharm Des. 2014;20(15):2525-38. Review.

PMID:
23859550
44.

Increased excitability in tat-transgenic mice: role of tat in HIV-related neurological disorders.

Zucchini S, Pittaluga A, Brocca-Cofano E, Summa M, Fabris M, De Michele R, Bonaccorsi A, Busatto G, Barbanti-Brodano G, Altavilla G, Verlengia G, Cifelli P, Corallini A, Caputo A, Simonato M.

Neurobiol Dis. 2013 Jul;55:110-9. doi: 10.1016/j.nbd.2013.02.004. Epub 2013 Feb 27.

PMID:
23454193
45.

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors.

Nasca C, Xenos D, Barone Y, Caruso A, Scaccianoce S, Matrisciano F, Battaglia G, Mathé AA, Pittaluga A, Lionetto L, Simmaco M, Nicoletti F.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4804-9. doi: 10.1073/pnas.1216100110. Epub 2013 Feb 4.

46.

Effects of the neoclerodane Hardwickiic acid on the presynaptic opioid receptors which modulate noradrenaline and dopamine release in mouse central nervous system.

Pittaluga A, Olivero G, Di Prisco S, Merega E, Bisio A, Romussi G, Grilli M, Marchi M.

Neurochem Int. 2013 Mar;62(4):354-9. doi: 10.1016/j.neuint.2013.01.016. Epub 2013 Jan 26.

PMID:
23357481
47.

Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus.

Marrocco J, Mairesse J, Ngomba RT, Silletti V, Van Camp G, Bouwalerh H, Summa M, Pittaluga A, Nicoletti F, Maccari S, Morley-Fletcher S.

J Neurosci. 2012 Nov 28;32(48):17143-54. doi: 10.1523/JNEUROSCI.1040-12.2012.

48.

Exposure to predator odor and resulting anxiety enhances the expression of the α2 δ subunit of voltage-sensitive calcium channels in the amygdala.

Nasca C, Orlando R, Marchiafava M, Boldrini P, Battaglia G, Scaccianoce S, Matrisciano F, Pittaluga A, Nicoletti F.

J Neurochem. 2013 Jun;125(5):649-56. doi: 10.1111/j.1471-4159.2012.07895.x. Epub 2013 Jan 8.

49.

Compensatory molecular and functional mechanisms in nervous system of the Grm1(crv4) mouse lacking the mGlu1 receptor: a model for motor coordination deficits.

Rossi PI, Musante I, Summa M, Pittaluga A, Emionite L, Ikehata M, Rastaldi MP, Ravazzolo R, Puliti A.

Cereb Cortex. 2013 Sep;23(9):2179-89. doi: 10.1093/cercor/bhs200. Epub 2012 Jul 12.

PMID:
22791805
50.

In vitro exposure to nicotine induces endocytosis of presynaptic AMPA receptors modulating dopamine release in rat nucleus accumbens nerve terminals.

Grilli M, Summa M, Salamone A, Olivero G, Zappettini S, Di Prisco S, Feligioni M, Usai C, Pittaluga A, Marchi M.

Neuropharmacology. 2012 Oct;63(5):916-26. doi: 10.1016/j.neuropharm.2012.06.049. Epub 2012 Jul 5.

PMID:
22771975

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