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Items: 1 to 50 of 167

1.

IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.

Liu Q, Dwyer GK, Zhao Y, Li H, Mathews LR, Chakka AB, Chandran UR, Demetris JA, Alcorn JF, Robinson KM, Ortiz LA, Pitt BR, Thomson AW, Fan MH, Billiar TR, Turnquist HR.

JCI Insight. 2019 Mar 21;4(6). pii: 123919. doi: 10.1172/jci.insight.123919. eCollection 2019 Mar 21.

2.

Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1-αvβ5 integrin pathway in TLR4-mediated inflammation and injury.

Ding X, Tong Y, Jin S, Chen Z, Li T, Billiar TR, Pitt BR, Li Q, Zhang LM.

Crit Care. 2018 Nov 16;22(1):302. doi: 10.1186/s13054-018-2237-0.

3.

The IL-33-ST2 Pathway Contributes to Ventilator-Induced Lung Injury in Septic Mice in a Tidal Volume-Dependent Manner.

Ding X, Jin S, Shao Z, Xu L, Yu Z, Tong Y, Chen Z, Turnquist H, Pitt BR, Billiar TR, Zhang LM, Li Q.

Shock. 2018 Sep 5. doi: 10.1097/SHK.0000000000001260. [Epub ahead of print]

PMID:
30192340
4.

Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.

Buland JR, Wasserloos KJ, Tyurin VA, Tyurina YY, Amoscato AA, Mallampalli RK, Chen BB, Zhao J, Zhao Y, Ofori-Acquah S, Kagan VE, Pitt BR.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L303-16. doi: 10.1152/ajplung.00038.2016. Epub 2016 May 27.

5.

Are plasma mineral levels related to antibody response to influenza vaccination in older adults?

Kaynar AM, Nowalk MP, Lin CJ, Moehling KK, Susick M, Bakalov V, Pitt BR, Bain DJ, Ross TM, Saul SG, Raymund M, Zimmerman RK.

Hum Vaccin Immunother. 2016 Apr 2;12(4):1003-8. doi: 10.1080/21645515.2015.1113358. Epub 2016 Jan 11.

6.

Perinatal outcomes and unconventional natural gas operations in Southwest Pennsylvania.

Stacy SL, Brink LL, Larkin JC, Sadovsky Y, Goldstein BD, Pitt BR, Talbott EO.

PLoS One. 2015 Jun 3;10(6):e0126425. doi: 10.1371/journal.pone.0126425. eCollection 2015.

7.

A mitochondrial pathway for biosynthesis of lipid mediators.

Tyurina YY, Poloyac SM, Tyurin VA, Kapralov AA, Jiang J, Anthonymuthu TS, Kapralova VI, Vikulina AS, Jung MY, Epperly MW, Mohammadyani D, Klein-Seetharaman J, Jackson TC, Kochanek PM, Pitt BR, Greenberger JS, Vladimirov YA, Bayır H, Kagan VE.

Nat Chem. 2014 Jun;6(6):542-52. doi: 10.1038/nchem.1924. Epub 2014 Apr 20.

8.

Improved spatial resolution of matrix-assisted laser desorption/ionization imaging of lipids in the brain by alkylated derivatives of 2,5-dihydroxybenzoic acid.

Stoyanovsky DA, Sparvero LJ, Amoscato AA, He RR, Watkins S, Pitt BR, Bayir H, Kagan VE.

Rapid Commun Mass Spectrom. 2014 Mar 15;28(5):403-12. doi: 10.1002/rcm.6796.

9.

Protein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular endothelial growth factor signaling and enables endothelial cell motility.

Zimmerman MW, McQueeney KE, Isenberg JS, Pitt BR, Wasserloos KA, Homanics GE, Lazo JS.

J Biol Chem. 2014 Feb 28;289(9):5904-13. doi: 10.1074/jbc.M113.480038. Epub 2014 Jan 8.

10.

Caveolae-dependent and -independent uptake of albumin in cultured rodent pulmonary endothelial cells.

Li HH, Li J, Wasserloos KJ, Wallace C, Sullivan MG, Bauer PM, Stolz DB, Lee JS, Watkins SC, St Croix CM, Pitt BR, Zhang LM.

PLoS One. 2013 Nov 27;8(11):e81903. doi: 10.1371/journal.pone.0081903. eCollection 2013.

11.

Functional role of intracellular labile zinc in pulmonary endothelium.

Thambiayya K, Kaynar AM, St Croix CM, Pitt BR.

Pulm Circ. 2012 Oct;2(4):443-51. doi: 10.4103/2045-8932.105032.

12.

Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.

Lee SM, McLaughlin JN, Frederick DR, Zhu L, Thambiayya K, Wasserloos KJ, Kaminski I, Pearce LL, Peterson J, Li J, Latoche JD, Peck Palmer OM, Stolz DB, Fattman CL, Alcorn JF, Oury TD, Angus DC, Pitt BR, Kaynar AM.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L350-60. doi: 10.1152/ajplung.00243.2012. Epub 2012 Dec 28.

13.

Inducible nitric oxide synthase contributes to immune dysfunction following trauma.

Darwiche SS, Pfeifer R, Menzel C, Ruan X, Hoffman M, Cai C, Chanthaphavong RS, Loughran P, Pitt BR, Hoffman R, Pape HC, Billiar TR.

Shock. 2012 Nov;38(5):499-507. doi: 10.1097/SHK.0b013e31826c5afe.

14.

Probing the structural basis of Zn2+ regulation of the epithelial Na+ channel.

Chen J, Winarski KL, Myerburg MM, Pitt BR, Sheng S.

J Biol Chem. 2012 Oct 12;287(42):35589-98. doi: 10.1074/jbc.M112.394734. Epub 2012 Aug 28.

15.

WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury.

Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM.

Am J Respir Cell Mol Biol. 2012 Oct;47(4):528-35. doi: 10.1165/rcmb.2012-0127OC. Epub 2012 Jun 14.

16.

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations.

Sparvero LJ, Amoscato AA, Dixon CE, Long JB, Kochanek PM, Pitt BR, Bayir H, Kagan VE.

Chem Phys Lipids. 2012 Jul;165(5):545-62. doi: 10.1016/j.chemphyslip.2012.06.001. Epub 2012 Jun 9. Review.

17.

Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel.

Cioffi DL, Wu S, Chen H, Alexeyev M, St Croix CM, Pitt BR, Uhlig S, Stevens T.

Circ Res. 2012 May 25;110(11):1435-44. doi: 10.1161/CIRCRESAHA.112.269506. Epub 2012 Apr 24.

18.

A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis.

Thambiayya K, Wasserloos K, Kagan VE, Stoyanovsky D, Pitt BR.

Am J Physiol Lung Cell Mol Physiol. 2012 Jun 15;302(12):L1287-95. doi: 10.1152/ajplung.00385.2011. Epub 2012 Apr 20.

19.

Iron-induced remodeling in cultured rat pulmonary artery endothelial cells.

Gorbunov NV, Atkins JL, Gurusamy N, Pitt BR.

Biometals. 2012 Feb;25(1):203-17. doi: 10.1007/s10534-011-9498-2. Epub 2011 Nov 17.

PMID:
22089858
20.

A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death.

Atkinson J, Kapralov AA, Yanamala N, Tyurina YY, Amoscato AA, Pearce L, Peterson J, Huang Z, Jiang J, Samhan-Arias AK, Maeda A, Feng W, Wasserloos K, Belikova NA, Tyurin VA, Wang H, Fletcher J, Wang Y, Vlasova II, Klein-Seetharaman J, Stoyanovsky DA, Bayîr H, Pitt BR, Epperly MW, Greenberger JS, Kagan VE.

Nat Commun. 2011 Oct 11;2:497. doi: 10.1038/ncomms1499.

21.

Physiology, reductionism, and translational medicine: the right mix.

Pitt BR, Christman JW, Gunst SJ, Matthay MA, Stevens T, Ware LB.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L389-90. doi: 10.1152/ajplung.00270.2011. Epub 2011 Aug 19. No abstract available.

22.

Acute, sublethal cyanide poisoning in mice is ameliorated by nitrite alone: complications arising from concomitant administration of nitrite and thiosulfate as an antidotal combination.

Cambal LK, Swanson MR, Yuan Q, Weitz AC, Li HH, Pitt BR, Pearce LL, Peterson J.

Chem Res Toxicol. 2011 Jul 18;24(7):1104-12. doi: 10.1021/tx2001042. Epub 2011 May 11.

23.

A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium.

Bernal PJ, Bauer EM, Cao R, Maniar S, Mosher M, Chen J, Wang QJ, Glorioso JC, Pitt BR, Watkins SC, St Croix CM.

Am J Physiol Lung Cell Mol Physiol. 2011 Jun;300(6):L874-86. doi: 10.1152/ajplung.00328.2010. Epub 2011 Mar 4.

24.

Oxidative lipidomics of γ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation.

Tyurina YY, Tyurin VA, Kapralova VI, Wasserloos K, Mosher M, Epperly MW, Greenberger JS, Pitt BR, Kagan VE.

Radiat Res. 2011 May;175(5):610-21. doi: 10.1667/RR2297.1. Epub 2011 Feb 21.

25.

LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells.

Thambiayya K, Wasserloos KJ, Huang Z, Kagan VE, St Croix CM, Pitt BR.

Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L624-32. doi: 10.1152/ajplung.00376.2010. Epub 2011 Jan 14.

26.

Cytoprotective effects of albumin, nitrosated or reduced, in cultured rat pulmonary vascular cells.

Li HH, Xu J, Wasserloos KJ, Li J, Tyurina YY, Kagan VE, Wang X, Chen AF, Liu ZQ, Stoyanovsky D, Pitt BR, Zhang LM.

Am J Physiol Lung Cell Mol Physiol. 2011 Apr;300(4):L526-33. doi: 10.1152/ajplung.00282.2010. Epub 2011 Jan 14.

27.

Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients.

Phillippi JA, Eskay MA, Kubala AA, Pitt BR, Gleason TG.

Ann Thorac Surg. 2010 Dec;90(6):1893-8. doi: 10.1016/j.athoracsur.2010.07.069.

PMID:
21095332
28.

Zinc in innate and adaptive tumor immunity.

John E, Laskow TC, Buchser WJ, Pitt BR, Basse PH, Butterfield LH, Kalinski P, Lotze MT.

J Transl Med. 2010 Nov 18;8:118. doi: 10.1186/1479-5876-8-118. Review.

29.

Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury.

Sparvero LJ, Amoscato AA, Kochanek PM, Pitt BR, Kagan VE, Bayir H.

J Neurochem. 2010 Dec;115(6):1322-36. doi: 10.1111/j.1471-4159.2010.07055.x. Epub 2010 Nov 19. Review.

30.

Nitric oxide and zinc homeostasis in pulmonary endothelium.

Li H, Cao R, Wasserloos KJ, Bernal P, Liu ZQ, Pitt BR, St Croix CM.

Ann N Y Acad Sci. 2010 Aug;1203:73-8. doi: 10.1111/j.1749-6632.2010.05558.x. Review.

PMID:
20716286
31.

Toll-like receptor 4-myeloid differentiation factor 88 signaling contributes to ventilator-induced lung injury in mice.

Li H, Su X, Yan X, Wasserloos K, Chao W, Kaynar AM, Liu ZQ, Leikauf GD, Pitt BR, Zhang LM.

Anesthesiology. 2010 Sep;113(3):619-29. doi: 10.1097/ALN.0b013e3181e89ab2.

32.

S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate.

Szczepaniak WS, Pitt BR, McVerry BJ.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L137-45. doi: 10.1152/ajplung.00233.2009. Epub 2010 Apr 30.

33.

Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation.

Tyurina YY, Tyurin VA, Kaynar AM, Kapralova VI, Wasserloos K, Li J, Mosher M, Wright L, Wipf P, Watkins S, Pitt BR, Kagan VE.

Am J Physiol Lung Cell Mol Physiol. 2010 Jul;299(1):L73-85. doi: 10.1152/ajplung.00035.2010. Epub 2010 Apr 23.

34.

Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions.

Kagan VE, Wipf P, Stoyanovsky D, Greenberger JS, Borisenko G, Belikova NA, Yanamala N, Samhan Arias AK, Tungekar MA, Jiang J, Tyurina YY, Ji J, Klein-Seetharaman J, Pitt BR, Shvedova AA, Bayir H.

Adv Drug Deliv Rev. 2009 Nov 30;61(14):1375-85. doi: 10.1016/j.addr.2009.06.008. Epub 2009 Aug 27. Review.

35.

Specific fluorogenic probes for ozone in biological and atmospheric samples.

Garner AL, St Croix CM, Pitt BR, Leikauf GD, Ando S, Koide K.

Nat Chem. 2009 Jul;1(4):316-21. doi: 10.1038/nchem.240.

36.

Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.

Nemec AA, Leikauf GD, Pitt BR, Wasserloos KJ, Barchowsky A.

Am J Respir Cell Mol Biol. 2009 Jul;41(1):69-75. doi: 10.1165/rcmb.2008-0409OC. Epub 2008 Dec 18.

37.

Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone.

Bernal PJ, Leelavanichkul K, Bauer E, Cao R, Wilson A, Wasserloos KJ, Watkins SC, Pitt BR, St Croix CM.

Circ Res. 2008 Jun 20;102(12):1575-83. doi: 10.1161/CIRCRESAHA.108.171264. Epub 2008 May 15.

38.

Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury.

Kaynar AM, Houghton AM, Lum EH, Pitt BR, Shapiro SD.

Am J Respir Cell Mol Biol. 2008 Jul;39(1):53-60. doi: 10.1165/rcmb.2007-0315OC. Epub 2008 Feb 14.

39.

Epithelial expression of TIMP-1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice.

Fattman CL, Gambelli F, Hoyle G, Pitt BR, Ortiz LA.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L572-81. doi: 10.1152/ajplung.00291.2007. Epub 2008 Jan 4.

40.

Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice.

Kleinschmidt AM, Nassiri M, Stitt MS, Wasserloos K, Watkins SC, Pitt BR, Jahroudi N.

J Biol Chem. 2008 Feb 1;283(5):2741-50. Epub 2007 Nov 28.

41.

FXR-mediated regulation of eNOS expression in vascular endothelial cells.

Li J, Wilson A, Kuruba R, Zhang Q, Gao X, He F, Zhang LM, Pitt BR, Xie W, Li S.

Cardiovasc Res. 2008 Jan;77(1):169-77. Epub 2007 Sep 19.

PMID:
18006476
42.

FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.

Zhang Q, He F, Kuruba R, Gao X, Wilson A, Li J, Billiar TR, Pitt BR, Xie W, Li S.

Cardiovasc Res. 2008 Feb 1;77(3):560-9. Epub 2007 Nov 13.

PMID:
18006431
43.

Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation.

Tyurina YY, Basova LV, Konduru NV, Tyurin VA, Potapovich AI, Cai P, Bayir H, Stoyanovsky D, Pitt BR, Shvedova AA, Fadeel B, Kagan VE.

J Biol Chem. 2007 Mar 16;282(11):8498-509. Epub 2007 Jan 17.

44.

Cell-surface protein disulfide isomerase is required for transnitrosation of metallothionein by S-nitroso-albumin in intact rat pulmonary vascular endothelial cells.

Zhang LM, St Croix C, Cao R, Wasserloos K, Watkins SC, Stevens T, Li S, Tyurin V, Kagan VE, Pitt BR.

Exp Biol Med (Maywood). 2006 Oct;231(9):1507-15.

PMID:
17018873
45.

Perspectives, translational research, and letters to the editor.

Matthay MA, Christman JW, Pitt BR, Schwiebert LM, Stevens T, Ware LB.

Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L621. No abstract available.

46.

Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein.

Stitt MS, Wasserloos KJ, Tang X, Liu X, Pitt BR, St Croix CM.

Vascul Pharmacol. 2006 Mar;44(3):149-55. Epub 2006 Jan 19.

PMID:
16423564
47.

Fluorescence resonance energy transfer-based assays for the real-time detection of nitric oxide signaling.

St Croix CM, Stitt MS, Watkins SC, Pitt BR.

Methods Enzymol. 2005;396:317-26.

PMID:
16291241
48.

Nitric oxide and zinc homeostasis in acute lung injury.

St Croix CM, Leelavaninchkul K, Watkins SC, Kagan VE, Pitt BR.

Proc Am Thorac Soc. 2005;2(3):236-42. Review.

49.

Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis?

Tyurina YY, Tyurin VA, Zhao Q, Djukic M, Quinn PJ, Pitt BR, Kagan VE.

Biochem Biophys Res Commun. 2004 Nov 19;324(3):1059-64.

PMID:
15485662
50.

Nitric oxide-induced modification of protein thiolate clusters as determined by spectral fluorescence resonance energy transfer in live endothelial cells.

St Croix CM, Stitt MS, Leelavanichkul K, Wasserloos KJ, Pitt BR, Watkins SC.

Free Radic Biol Med. 2004 Sep 15;37(6):785-92.

PMID:
15304254

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