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Items: 28

1.

Childhood exposure to passive smoking and bone health in adulthood. The Cardiovascular Risk in Young Finns Study.

Juonala M, Pitkänen N, Tolonen S, Laaksonen M, Sievänen H, Jokinen E, Laitinen T, Sabin MA, Hutri-Kähönen N, Lehtimäki T, Taittonen L, Jula A, Loo BM, Impivaara O, Kähönen M, Magnussen CG, Viikari JSA, Raitakari OT.

J Clin Endocrinol Metab. 2019 Feb 1. doi: 10.1210/jc.2018-02501. [Epub ahead of print]

PMID:
30715377
2.

Youth and long-term dietary calcium intake with risk of impaired glucose metabolism and type 2 diabetes in adulthood.

Wu F, Juonala M, Pahkala K, Buscot MJ, Sabin MA, Pitkänen N, Rönnemaa T, Jula A, Lehtimäki T, Hutri-Kähönen N, Kähönen M, Laitinen T, Viikari JSA, Raitakari OT, Magnussen CG.

J Clin Endocrinol Metab. 2019 Jan 9. doi: 10.1210/jc.2018-02321. [Epub ahead of print]

PMID:
30629189
3.

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, Nolte IM, Lu L, Scholz M, Sargurupremraj M, Pitkänen N, Franzén O, Joshi PK, Noordam R, Marioni RE, Hwang SJ, Musani SK, Schminke U, Palmas W, Isaacs A, Correa A, Zonderman AB, Hofman A, Teumer A, Cox AJ, Uitterlinden AG, Wong A, Smit AJ, Newman AB, Britton A, Ruusalepp A, Sennblad B, Hedblad B, Pasaniuc B, Penninx BW, Langefeld CD, Wassel CL, Tzourio C, Fava C, Baldassarre D, O'Leary DH, Teupser D, Kuh D, Tremoli E, Mannarino E, Grossi E, Boerwinkle E, Schadt EE, Ingelsson E, Veglia F, Rivadeneira F, Beutner F, Chauhan G, Heiss G, Snieder H, Campbell H, Völzke H, Markus HS, Deary IJ, Jukema JW, de Graaf J, Price J, Pott J, Hopewell JC, Liang J, Thiery J, Engmann J, Gertow K, Rice K, Taylor KD, Dhana K, Kiemeney LALM, Lind L, Raffield LM, Launer LJ, Holdt LM, Dörr M, Dichgans M, Traylor M, Sitzer M, Kumari M, Kivimaki M, Nalls MA, Melander O, Raitakari O, Franco OH, Rueda-Ochoa OL, Roussos P, Whincup PH, Amouyel P, Giral P, Anugu P, Wong Q, Malik R, Rauramaa R, Burkhardt R, Hardy R, Schmidt R, de Mutsert R, Morris RW, Strawbridge RJ, Wannamethee SG, Hägg S, Shah S, McLachlan S, Trompet S, Seshadri S, Kurl S, Heckbert SR, Ring S, Harris TB, Lehtimäki T, Galesloot TE, Shah T, de Faire U, Plagnol V, Rosamond WD, Post W, Zhu X, Zhang X, Guo X, Saba Y; MEGASTROKE Consortium, Dehghan A, Seldenrijk A, Morrison AC, Hamsten A, Psaty BM, van Duijn CM, Lawlor DA, Mook-Kanamori DO, Bowden DW, Schmidt H, Wilson JF, Wilson JG, Rotter JI, Wardlaw JM, Deanfield J, Halcox J, Lyytikäinen LP, Loeffler M, Evans MK, Debette S, Humphries SE, Völker U, Gudnason V, Hingorani AD, Björkegren JLM, Casas JP, O'Donnell CJ.

Nat Commun. 2018 Dec 3;9(1):5141. doi: 10.1038/s41467-018-07340-5.

4.

Does education protect against depression? Evidence from the Young Finns Study using Mendelian randomization.

Viinikainen J, Bryson A, Böckerman P, Elovainio M, Pitkänen N, Pulkki-Råback L, Lehtimäki T, Raitakari O, Pehkonen J.

Prev Med. 2018 Oct;115:134-139. doi: 10.1016/j.ypmed.2018.08.026. Epub 2018 Aug 23.

PMID:
30145350
5.

Serum Proteomic Profiling to Identify Biomarkers of Premature Carotid Atherosclerosis.

Bhosale SD, Moulder R, Venäläinen MS, Koskinen JS, Pitkänen N, Juonala MT, Kähönen MAP, Lehtimäki TJ, Viikari JSA, Elo LL, Goodlett DR, Lahesmaa R, Raitakari OT.

Sci Rep. 2018 Jun 15;8(1):9209. doi: 10.1038/s41598-018-27265-9.

6.

Genetic polymorphism of sterol transporters in children with future gallstones.

Nissinen MJ, Pitkänen N, Simonen P, Gylling H, Viikari J, Raitakari O, Lehtimäki T, Juonala M, Pakarinen MP.

Dig Liver Dis. 2018 Sep;50(9):954-960. doi: 10.1016/j.dld.2018.04.007. Epub 2018 Apr 26.

PMID:
29764733
7.

Low childhood high density lipoprotein cholesterol levels and subsequent risk for chronic inflammatory bowel disease.

Voutilainen M, Hutri-Kähönen N, Tossavainen P, Sipponen T, Pitkänen N, Laitinen T, Jokinen E, Rönnemaa T, Viikari JSA, Raitakari OT, Juonala M.

Dig Liver Dis. 2018 Apr;50(4):348-352. doi: 10.1016/j.dld.2018.01.121. Epub 2018 Jan 31.

PMID:
29426615
8.

Both youth and long-term vitamin D status is associated with risk of type 2 diabetes mellitus in adulthood: a cohort study.

Wu F, Juonala M, Pitkänen N, Jula A, Lehtimäki T, Sabin MA, Pahkala K, Hutri-Kähönen N, Kähönen M, Laitinen T, Viikari JSA, Magnussen CG, Raitakari OT.

Ann Med. 2018 Feb;50(1):74-82. doi: 10.1080/07853890.2017.1399446. Epub 2017 Nov 7.

PMID:
29113496
9.

Gene-environment interactions between education and body mass: Evidence from the UK and Finland.

Amin V, Böckerman P, Viinikainen J, Smart MC, Bao Y, Kumari M, Pitkänen N, Lehtimäki T, Raitakari O, Pehkonen J.

Soc Sci Med. 2017 Dec;195:12-16. doi: 10.1016/j.socscimed.2017.10.027. Epub 2017 Nov 3.

PMID:
29102742
10.

Maternal and fetal genetic contribution to gestational weight gain.

Warrington NM, Richmond R, Fenstra B, Myhre R, Gaillard R, Paternoster L, Wang CA, Beaumont RN, Das S, Murcia M, Barton SJ, Espinosa A, Thiering E, Atalay M, Pitkänen N, Ntalla I, Jonsson AE, Freathy R, Karhunen V, Tiesler CMT, Allard C, Crawford A, Ring SM, Melbye M, Magnus P, Rivadeneira F, Skotte L, Hansen T, Marsh J, Guxens M, Holloway JW, Grallert H, Jaddoe VWV, Lowe WL Jr, Roumeliotaki T, Hattersley AT, Lindi V, Pahkala K, Panoutsopoulou K, Standl M, Flexeder C, Bouchard L, Aagaard Nohr E, Marina LS, Kogevinas M, Niinikoski H, Dedoussis G, Heinrich J, Reynolds RM, Lakka T, Zeggini E, Raitakari OT, Chatzi L, Inskip HM, Bustamante M, Hivert MF, Jarvelin MR, Sørensen TIA, Pennell C, Felix JF, Jacobsson B, Geller F, Evans DM, Lawlor DA.

Int J Obes (Lond). 2018 Apr;42(4):775-784. doi: 10.1038/ijo.2017.248. Epub 2017 Oct 9.

11.

Fasting Glucose and the Risk of Depressive Symptoms: Instrumental-Variable Regression in the Cardiovascular Risk in Young Finns Study.

Wesołowska K, Elovainio M, Hintsa T, Jokela M, Pulkki-Råback L, Pitkänen N, Lipsanen J, Tukiainen J, Lyytikäinen LP, Lehtimäki T, Juonala M, Raitakari O, Keltikangas-Järvinen L.

Int J Behav Med. 2017 Dec;24(6):901-907. doi: 10.1007/s12529-017-9639-2.

PMID:
28779468
12.

Education as a moderator of genetic risk for higher body mass index: prospective cohort study from childhood to adulthood.

Komulainen K, Pulkki-Råback L, Jokela M, Lyytikäinen LP, Pitkänen N, Laitinen T, Hintsanen M, Elovainio M, Hintsa T, Jula A, Juonala M, Pahkala K, Viikari J, Lehtimäki T, Raitakari O, Keltikangas-Järvinen L.

Int J Obes (Lond). 2018 Apr;42(4):866-871. doi: 10.1038/ijo.2017.174. Epub 2017 Jul 31.

PMID:
28757641
13.

The challenges of GxE research: A rejoinder.

Pehkonen J, Viinikainen J, Böckerman P, Lehtimäki T, Pitkänen N, Raitakari O.

Soc Sci Med. 2017 Sep;188:204-205. doi: 10.1016/j.socscimed.2017.07.010. Epub 2017 Jul 20. No abstract available.

PMID:
28750726
14.

Does higher education protect against obesity? Evidence using Mendelian randomization.

Böckerman P, Viinikainen J, Pulkki-Råback L, Hakulinen C, Pitkänen N, Lehtimäki T, Pehkonen J, Raitakari OT.

Prev Med. 2017 Aug;101:195-198. doi: 10.1016/j.ypmed.2017.06.015. Epub 2017 Jun 21.

PMID:
28645627
15.

Prediction of Adult Dyslipidemia Using Genetic and Childhood Clinical Risk Factors: The Cardiovascular Risk in Young Finns Study.

Nuotio J, Pitkänen N, Magnussen CG, Buscot MJ, Venäläinen MS, Elo LL, Jokinen E, Laitinen T, Taittonen L, Hutri-Kähönen N, Lyytikäinen LP, Lehtimäki T, Viikari JS, Juonala M, Raitakari OT.

Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001604. doi: 10.1161/CIRCGENETICS.116.001604.

PMID:
28620070
16.

Prediction of Adulthood Obesity Using Genetic and Childhood Clinical Risk Factors in the Cardiovascular Risk in Young Finns Study.

Seyednasrollah F, Mäkelä J, Pitkänen N, Juonala M, Hutri-Kähönen N, Lehtimäki T, Viikari J, Kelly T, Li C, Bazzano L, Elo LL, Raitakari OT.

Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001554. doi: 10.1161/CIRCGENETICS.116.001554.

PMID:
28620069
17.

Genetic endowments, parental resources and adult health: Evidence from the Young Finns Study.

Pehkonen J, Viinikainen J, Böckerman P, Lehtimäki T, Pitkänen N, Raitakari O.

Soc Sci Med. 2017 Sep;188:191-200. doi: 10.1016/j.socscimed.2017.04.030. Epub 2017 Apr 21.

PMID:
28457598
18.

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.

Ahola-Olli AV, Würtz P, Havulinna AS, Aalto K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salomaa V, Salmi M, Kettunen J, Raitakari OT.

Am J Hum Genet. 2017 Jan 5;100(1):40-50. doi: 10.1016/j.ajhg.2016.11.007. Epub 2016 Dec 15.

19.

Stature and long-term labor market outcomes: Evidence using Mendelian randomization.

Böckerman P, Viinikainen J, Vainiomäki J, Hintsanen M, Pitkänen N, Lehtimäki T, Pehkonen J, Rovio S, Raitakari O.

Econ Hum Biol. 2017 Feb;24:18-29. doi: 10.1016/j.ehb.2016.10.009. Epub 2016 Nov 8.

PMID:
27846416
20.

Genome-wide associations for birth weight and correlations with adult disease.

Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ETH, Ntalla I, Pitkänen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RCW, Tam CHT, Tam WH; CHARGE Consortium Hematology Working Group, Ganesh SK, van Rooij FJ, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EVR, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonas-Guarch S, Hougaard DM, Sánchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM; Early Growth Genetics (EGG) Consortium, Lowe WL Jr, Tönjes A, Stumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Körner A, Sørensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Kähönen M, Viikari JS, Lehtimäki T, Vollenweider P, Bønnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hyppönen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Jarvelin MR, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Davey Smith G, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM.

Nature. 2016 Oct 13;538(7624):248-252. doi: 10.1038/nature19806. Epub 2016 Sep 28.

21.

Role of Conventional Childhood Risk Factors Versus Genetic Risk in the Development of Type 2 Diabetes and Impaired Fasting Glucose in Adulthood: The Cardiovascular Risk in Young Finns Study.

Pitkänen N, Juonala M, Rönnemaa T, Sabin MA, Hutri-Kähönen N, Kähönen M, Lehtimäki T, Viikari JS, Raitakari OT.

Diabetes Care. 2016 Aug;39(8):1393-9. doi: 10.2337/dc16-0167. Epub 2016 Jun 13.

PMID:
27298332
22.

Childhood predictors of adult fatty liver. The Cardiovascular Risk in Young Finns Study.

Suomela E, Oikonen M, Pitkänen N, Ahola-Olli A, Virtanen J, Parkkola R, Jokinen E, Laitinen T, Hutri-Kähönen N, Kähönen M, Lehtimäki T, Taittonen L, Tossavainen P, Jula A, Loo BM, Mikkilä V, Telama R, Viikari JSA, Juonala M, Raitakari OT.

J Hepatol. 2016 Oct;65(4):784-790. doi: 10.1016/j.jhep.2016.05.020. Epub 2016 May 24.

PMID:
27235307
23.

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study.

Buscot MJ, Magnussen CG, Juonala M, Pitkänen N, Lehtimäki T, Viikari JS, Kähönen M, Hutri-Kähönen N, Schork NJ, Raitakari OT, Thomson RJ.

PLoS One. 2016 Jan 5;11(1):e0146081. doi: 10.1371/journal.pone.0146081. eCollection 2016.

24.

Genetic risk clustering increases children's body weight at 2 years of age - the STEPS Study.

Mäkelä J, Lagström H, Pitkänen N, Kuulasmaa T, Kaljonen A, Laakso M, Niinikoski H.

Pediatr Obes. 2016 Dec;11(6):459-467. doi: 10.1111/ijpo.12087. Epub 2015 Dec 11.

PMID:
26663901
25.

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.

Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L; Bone Mineral Density in Childhood Study (BMDCS); Early Genetics and Lifecourse Epidemiology (EAGLE) consortium, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen AL, Haworth CM, Hirschhorn JN, Hofman A, Holm JC, Horikoshi M, Hottenga JJ, Huang J, Kadarmideen HN, Kähönen M, Kiess W, Lakka HM, Lakka TA, Lewin AM, Liang L, Lyytikäinen LP, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfäffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CM, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis GV, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widén E, Boomsma DI, Koppelman GH, Sebert S, Järvelin MR, Hyppönen E, McCarthy MI, Lindi V, Harri N, Körner A, Bønnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sørensen TI, Timpson NJ, Grant SF, Jaddoe VW; Early Growth Genetics (EGG) Consortium; Bone Mineral Density in Childhood Study BMDCS.

Hum Mol Genet. 2016 Jan 15;25(2):389-403. doi: 10.1093/hmg/ddv472. Epub 2015 Nov 24.

26.

Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents.

Qi Q, Downer MK, Kilpeläinen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Körner A, Lakka TA, Liu G, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey ME, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossavar-Rahmani Y, Jaddoe VW, Laitinen J, Lindi V, Melén E, Pitsiladis Y, Pitkänen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis GV, Kaplan RC, Wylie-Rosett J, Loos RJ, Hu FB, Qi L.

Diabetes. 2015 Jul;64(7):2467-76. doi: 10.2337/db14-1629. Epub 2015 Feb 26.

27.

Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children.

Ahola-Olli AV, Pitkänen N, Kettunen J, Oikonen MK, Mikkilä V, Lehtimäki T, Kähönen M, Pahkala K, Niinikoski H, Kangas AJ, Soininen P, Ala-Korpela M, Viikari JS, Rönnemaa T, Simell O, Raitakari OT.

Am J Clin Nutr. 2014 Dec;100(6):1569-77. doi: 10.3945/ajcn.114.085027. Epub 2014 Oct 8.

PMID:
25411292
28.

A novel common variant in DCST2 is associated with length in early life and height in adulthood.

van der Valk RJ, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkänen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Davey Smith G, Bergström A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M; Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG; Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CM, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikäinen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw SM, Holloway JW, Melén E, Grant SF, Feenstra B, Lowe WL, Widén E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, Mccarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bønnelykke K, Jaddoe VW; Early Growth Genetics (EGG) Consortium.

Hum Mol Genet. 2015 Feb 15;24(4):1155-68. doi: 10.1093/hmg/ddu510. Epub 2014 Oct 3.

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