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Items: 35

1.

Vasodilator-Stimulated Phosphoprotein Biomarkers Are Associated with Invasion and Metastasis in Colorectal Cancer.

Pitari GM, Cotzia P, Ali M, Birbe R, Rizzo W, Bombonati A, Palazzo J, Solomides C, Shuber AP, Sinicrope FA, Zuzga DS.

Biomark Cancer. 2018 Jun 5;10:1179299X18774551. doi: 10.1177/1179299X18774551. eCollection 2018.

2.

Serine phosphorylation of vasodilator-stimulated phosphoprotein (VASP) regulates colon cancer cell survival and apoptosis.

Ali M, Rogers LK, Pitari GM.

Life Sci. 2015 Feb 15;123:1-8. doi: 10.1016/j.lfs.2014.12.018. Epub 2014 Dec 24.

PMID:
25543053
3.

Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.

Pitari GM.

Drug Des Devel Ther. 2013 Apr 19;7:351-60. doi: 10.2147/DDDT.S32252. Print 2013. Review.

4.

Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer.

Zuzga DS, Pelta-Heller J, Li P, Bombonati A, Waldman SA, Pitari GM.

Int J Cancer. 2012 Jun 1;130(11):2539-48. doi: 10.1002/ijc.26257. Epub 2011 Aug 12.

5.

Can colorectal cancer be prevented or treated by oral hormone replacement therapy?

Li P, Lin JE, Schulz S, Pitari GM, Waldman SA.

Curr Mol Pharmacol. 2009 Nov;2(3):285-92. Review.

6.

GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?

Li P, Lin JE, Marszlowicz GP, Valentino MA, Chang C, Schulz S, Pitari GM, Waldman SA.

Drug News Perspect. 2009 Jul-Aug;22(6):313-8. doi: 10.1358/dnp.2009.22.6.1395254. Review.

7.

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

Lin JE, Li P, Snook AE, Schulz S, Dasgupta A, Hyslop TM, Gibbons AV, Marszlowicz G, Pitari GM, Waldman SA.

Gastroenterology. 2010 Jan;138(1):241-54. doi: 10.1053/j.gastro.2009.08.064. Epub 2009 Sep 6.

8.

Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy.

Li P, Lin JE, Snook AE, Gibbons AV, Zuzga DS, Schulz S, Pitari GM, Waldman SA.

Clin Transl Sci. 2008 Sep;1(2):163-7. doi: 10.1111/j.1752-8062.2008.00040.x.

9.

Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.

Lin JE, Li P, Pitari GM, Schulz S, Waldman SA.

Future Oncol. 2009 May;5(4):509-22. doi: 10.2217/fon.09.14. Review.

10.

Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.

Lubbe WJ, Zuzga DS, Zhou Z, Fu W, Pelta-Heller J, Muschel RJ, Waldman SA, Pitari GM.

Cancer Res. 2009 Apr 15;69(8):3529-36. doi: 10.1158/0008-5472.CAN-09-0067. Epub 2009 Mar 31.

11.

Sex modulates intestinal transformation by the tumor-suppressor GCC.

Li P, Schulz S, Pitari GM, Waldman SA.

Clin Transl Sci. 2008 Sep;1(2):150. doi: 10.1111/j.1752-8062.2008.00010.x. No abstract available.

12.

Sex modulates intestinal transformation by the tumor-suppressor GCC.

Li P, Schulz S, Pitari GM, Waldman SA.

Clin Transl Sci. 2008 Sep;1(2):146-50. doi: 10.1111/j.1752-8062.2008.00029.x.

13.

Overexpression of matrix metalloproteinase 9 in tumor epithelial cells correlates with colorectal cancer metastasis.

Zuzga DS, Gibbons AV, Li P, Lubbe WJ, Chervoneva I, Pitari GM.

Clin Transl Sci. 2008 Sep;1(2):136-41. doi: 10.1111/j.1752-8062.2008.00037.x.

14.

Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells.

Pitari GM, Lin JE, Shah FJ, Lubbe WJ, Zuzga DS, Li P, Schulz S, Waldman SA.

Carcinogenesis. 2008 Aug;29(8):1601-7. doi: 10.1093/carcin/bgn148. Epub 2008 Jun 19.

15.

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

Li P, Lin JE, Chervoneva I, Schulz S, Waldman SA, Pitari GM.

Am J Pathol. 2007 Dec;171(6):1847-58. Epub 2007 Nov 1.

16.

The paracrine hormone hypothesis of colorectal cancer.

Pitari GM, Li P, Lin JE, Zuzga D, Gibbons AV, Snook AE, Schulz S, Waldman SA.

Clin Pharmacol Ther. 2007 Oct;82(4):441-7. Epub 2007 Aug 8. Review.

PMID:
17687268
17.

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.

Li P, Schulz S, Bombonati A, Palazzo JP, Hyslop TM, Xu Y, Baran AA, Siracusa LD, Pitari GM, Waldman SA.

Gastroenterology. 2007 Aug;133(2):599-607. Epub 2007 Jun 2.

PMID:
17681179
18.
19.

Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.

Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Cell C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA.

Gastroenterology. 2006 Apr;130(4):1191-206.

PMID:
16618413
20.

Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.

Lubbe WJ, Zhou ZY, Fu W, Zuzga D, Schulz S, Fridman R, Muschel RJ, Waldman SA, Pitari GM.

Clin Cancer Res. 2006 Mar 15;12(6):1876-82.

21.
22.

Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer.

Frick GS, Pitari GM, Weinberg DS, Hyslop T, Schulz S, Waldman SA.

Expert Rev Mol Diagn. 2005 Sep;5(5):701-13. Review.

PMID:
16149873
23.

Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.

Kazerounian S, Pitari GM, Shah FJ, Frick GS, Madesh M, Ruiz-Stewart I, Schulz S, Hajnóczky G, Waldman SA.

J Pharmacol Exp Ther. 2005 Sep;314(3):1013-22. Epub 2005 Jun 3.

PMID:
15937149
24.

Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP.

Tiyyagura SR, Kazerounian S, Schulz S, Waldman SA, Pitari GM.

Vitam Horm. 2004;69:69-94. Review.

PMID:
15196879
25.

Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism.

Ruiz-Stewart I, Tiyyagura SR, Lin JE, Kazerounian S, Pitari GM, Schulz S, Martin E, Murad F, Waldman SA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):37-42. Epub 2003 Dec 18.

26.

Nitric oxide signaling: systems integration of oxygen balance in defense of cell integrity.

Gong L, Pitari GM, Schulz S, Waldman SA.

Curr Opin Hematol. 2004 Jan;11(1):7-14. Review.

PMID:
14676622
27.

Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation.

Burke J, Kraft WK, Greenberg HE, Gleave M, Pitari GM, VanBuren S, Wagner JA, Waldman SA.

J Clin Pharmacol. 2003 Sep;43(9):983-9.

PMID:
12971030
28.

Bacterial enterotoxins are associated with resistance to colon cancer.

Pitari GM, Zingman LV, Hodgson DM, Alekseev AE, Kazerounian S, Bienengraeber M, Hajnóczky G, Terzic A, Waldman SA.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2695-9. Epub 2003 Feb 19.

29.

Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta.

Chiarugi A, Pitari GM, Costa R, Ferrante M, Villari L, Amico-Roxas M, Godfraind T, Bianchi A, Salomone S.

Br J Pharmacol. 2002 Aug;136(8):1185-93.

30.

Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides.

Ruiz-Stewart I, Kazerounian S, Pitari GM, Schulz S, Waldman SA.

Eur J Biochem. 2002 Apr;269(8):2186-93.

31.

Nitric oxide activation of soluble guanylyl cyclase reveals high and low affinity sites that mediate allosteric inhibition by calcium.

Kazerounian S, Pitari GM, Ruiz-Stewart I, Schulz S, Waldman SA.

Biochemistry. 2002 Mar 12;41(10):3396-404.

PMID:
11876648
32.

Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.

Pitari GM, Di Guglielmo MD, Park J, Schulz S, Waldman SA.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7846-51.

33.

Comparison of pharmacological treatment versus acupuncture treatment for migraine without aura--analysis of socio-medical parameters.

Liguori A, Petti F, Bangrazi A, Camaioni D, Guccione G, Pitari GM, Bianchi A, Nicoletti WE.

J Tradit Chin Med. 2000 Sep;20(3):231-40.

PMID:
11038990
34.

Guanylyl cyclases and signaling by cyclic GMP.

Lucas KA, Pitari GM, Kazerounian S, Ruiz-Stewart I, Park J, Schulz S, Chepenik KP, Waldman SA.

Pharmacol Rev. 2000 Sep;52(3):375-414. Review.

PMID:
10977868
35.

Nitric oxide plasma levels in patients with chronic and acute cerebrovascular disorders.

Ferlito S, Gallina M, Pitari GM, Bianchi A.

Panminerva Med. 1998 Mar;40(1):51-4.

PMID:
9573755

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