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Items: 41


Inactivation of Proprotein Convertases in T Cells Inhibits PD-1 Expression and Creates a Favorable Immune Microenvironment in Colorectal Cancer.

Tomé M, Pappalardo A, Soulet F, López JJ, Olaizola J, Leger Y, Dubreuil M, Mouchard A, Fessart D, Delom F, Pitard V, Bechade D, Fonck M, Rosado JA, Ghiringhelli F, Déchanet-Merville J, Soubeyran I, Siegfried G, Evrard S, Khatib AM.

Cancer Res. 2019 Oct 1;79(19):5008-5021. doi: 10.1158/0008-5472.CAN-19-0086. Epub 2019 Jul 29.


Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2.

Marlin R, Pappalardo A, Kaminski H, Willcox CR, Pitard V, Netzer S, Khairallah C, Lomenech AM, Harly C, Bonneville M, Moreau JF, Scotet E, Willcox BE, Faustin B, Déchanet-Merville J.

Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3163-3168. doi: 10.1073/pnas.1621052114. Epub 2017 Mar 7.


TCR-dependent sensitization of human γδ T cells to non-myeloid IL-18 in cytomegalovirus and tumor stress surveillance.

Guerville F, Daburon S, Marlin R, Lartigue L, Loizon S, Pitard V, Couzi L, Moreau JF, Déchanet-Merville J, Faustin B.

Oncoimmunology. 2015 Feb 3;4(5):e1003011. eCollection 2015 May.


Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation.

Couzi L, Pitard V, Moreau JF, Merville P, Déchanet-Merville J.

Front Immunol. 2015 Jan 21;6:3. doi: 10.3389/fimmu.2015.00003. eCollection 2015. Review.


Role of Campylobacter jejuni gamma-glutamyl transpeptidase on epithelial cell apoptosis and lymphocyte proliferation.

Floch P, Pey V, Castroviejo M, Dupuy JW, Bonneu M, de la Guardia AH, Pitard V, Mégraud F, Lehours P.

Gut Pathog. 2014 Jun 12;6:20. doi: 10.1186/1757-4749-6-20. eCollection 2014.


Cytomegalovirus-responsive γδ T cells: novel effector cells in antibody-mediated kidney allograft microcirculation lesions.

Bachelet T, Couzi L, Pitard V, Sicard X, Rigothier C, Lepreux S, Moreau JF, Taupin JL, Merville P, Déchanet-Merville J.

J Am Soc Nephrol. 2014 Nov;25(11):2471-82. doi: 10.1681/ASN.2013101052. Epub 2014 Apr 17.


Anti-metastatic potential of human Vδ1(+) γδ T cells in an orthotopic mouse xenograft model of colon carcinoma.

Devaud C, Rousseau B, Netzer S, Pitard V, Paroissin C, Khairallah C, Costet P, Moreau JF, Couillaud F, Dechanet-Merville J, Capone M.

Cancer Immunol Immunother. 2013 Jul;62(7):1199-210. doi: 10.1007/s00262-013-1402-1. Epub 2013 Apr 26.


Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor.

Willcox CR, Pitard V, Netzer S, Couzi L, Salim M, Silberzahn T, Moreau JF, Hayday AC, Willcox BE, Déchanet-Merville J.

Nat Immunol. 2012 Sep;13(9):872-9. doi: 10.1038/ni.2394. Epub 2012 Aug 12.


A functional screening identifies five microRNAs controlling glypican-3: role of miR-1271 down-regulation in hepatocellular carcinoma.

Maurel M, Jalvy S, Ladeiro Y, Combe C, Vachet L, Sagliocco F, Bioulac-Sage P, Pitard V, Jacquemin-Sablon H, Zucman-Rossi J, Laloo B, Grosset CF.

Hepatology. 2013 Jan;57(1):195-204. doi: 10.1002/hep.25994.


Antibody-dependent anti-cytomegalovirus activity of human γδ T cells expressing CD16 (FcγRIIIa).

Couzi L, Pitard V, Sicard X, Garrigue I, Hawchar O, Merville P, Moreau JF, Déchanet-Merville J.

Blood. 2012 Feb 9;119(6):1418-27. doi: 10.1182/blood-2011-06-363655. Epub 2011 Dec 16.


Control of Plasmodium falciparum erythrocytic cycle: γδ T cells target the red blood cell-invasive merozoites.

Costa G, Loizon S, Guenot M, Mocan I, Halary F, de Saint-Basile G, Pitard V, Déchanet-Merville J, Moreau JF, Troye-Blomberg M, Mercereau-Puijalon O, Behr C.

Blood. 2011 Dec 22;118(26):6952-62. doi: 10.1182/blood-2011-08-376111. Epub 2011 Nov 1.


Gamma-delta T cell expansion is closely associated with cytomegalovirus infection in all solid organ transplant recipients.

Couzi L, Lafarge X, Pitard V, Neau-Cransac M, Dromer C, Billes MA, Lacaille F, Moreau JF, Merville P, Déchanet-Merville J.

Transpl Int. 2011 May;24(5):e40-2. doi: 10.1111/j.1432-2277.2010.01181.x. No abstract available.


Modeling of congenital erythropoietic porphyria by RNA interference: a new tool for preclinical gene therapy evaluation.

Robert-Richard E, Lalanne M, Lamrissi-Garcia I, Guyonnet-Duperat V, Richard E, Pitard V, Mazurier F, Moreau-Gaudry F, Ged C, de Verneuil H.

J Gene Med. 2010 Aug;12(8):637-46. doi: 10.1002/jgm.1478.


Common features of gammadelta T cells and CD8(+) alphabeta T cells responding to human cytomegalovirus infection in kidney transplant recipients.

Couzi L, Pitard V, Netzer S, Garrigue I, Lafon ME, Moreau JF, Taupin JL, Merville P, Déchanet-Merville J.

J Infect Dis. 2009 Nov 1;200(9):1415-24. doi: 10.1086/644509.


Cytomegalovirus-induced gammadelta T cells associate with reduced cancer risk after kidney transplantation.

Couzi L, Levaillant Y, Jamai A, Pitard V, Lassalle R, Martin K, Garrigue I, Hawchar O, Siberchicot F, Moore N, Moreau JF, Dechanet-Merville J, Merville P.

J Am Soc Nephrol. 2010 Jan;21(1):181-8. doi: 10.1681/ASN.2008101072. Epub 2009 Aug 27.


Antitumor activity of gammadelta T cells reactive against cytomegalovirus-infected cells in a mouse xenograft tumor model.

Devaud C, Bilhere E, Loizon S, Pitard V, Behr C, Moreau JF, Dechanet-Merville J, Capone M.

Cancer Res. 2009 May 1;69(9):3971-8. doi: 10.1158/0008-5472.CAN-08-3037. Epub 2009 Apr 21.


Long-term expansion of effector/memory Vdelta2-gammadelta T cells is a specific blood signature of CMV infection.

Pitard V, Roumanes D, Lafarge X, Couzi L, Garrigue I, Lafon ME, Merville P, Moreau JF, Déchanet-Merville J.

Blood. 2008 Aug 15;112(4):1317-24. doi: 10.1182/blood-2008-01-136713. Epub 2008 Jun 6.


Modulation of lymphocyte proliferation induced by gastric MALT lymphoma-associated Helicobacter pylori strains.

Ferrand J, Roumanes D, Pitard V, Moreau JF, Mégraud F, Lehours P.

Helicobacter. 2008 Jun;13(3):167-73. doi: 10.1111/j.1523-5378.2008.00596.x.


Shared reactivity of V{delta}2(neg) {gamma}{delta} T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cells.

Halary F, Pitard V, Dlubek D, Krzysiek R, de la Salle H, Merville P, Dromer C, Emilie D, Moreau JF, Déchanet-Merville J.

J Exp Med. 2005 May 16;201(10):1567-78.


Expression of MHC class I receptors confers functional intraclonal heterogeneity to a reactive expansion of gammadelta T cells.

Lafarge X, Pitard V, Ravet S, Roumanes D, Halary F, Dromer C, Vivier E, Paul P, Moreau JF, Déchanet-Merville J.

Eur J Immunol. 2005 Jun;35(6):1896-905.


Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus.

Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF.

Arthritis Rheum. 2005 Jan;52(1):201-11.


Coordinated expression of Ig-like inhibitory MHC class I receptors and acquisition of cytotoxic function in human CD8+ T cells.

Anfossi N, Doisne JM, Peyrat MA, Ugolini S, Bonnaud O, Bossy D, Pitard V, Merville P, Moreau JF, Delfraissy JF, Dechanet-Merville J, Bonneville M, Venet A, Vivier E.

J Immunol. 2004 Dec 15;173(12):7223-9.


Potential role of soluble CD40 in the humoral immune response impairment of uraemic patients.

Contin C, Pitard V, Delmas Y, Pelletier N, Defrance T, Moreau JF, Merville P, Déchanet-Merville J.

Immunology. 2003 Sep;110(1):131-40.


Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling.

Contin C, Pitard V, Itai T, Nagata S, Moreau JF, Déchanet-Merville J.

J Biol Chem. 2003 Aug 29;278(35):32801-9. Epub 2003 Jun 16.


T-lymphocyte populations in hepatitis C and HIV co-infected patients treated with interferon-alfa-2a and ribavirin.

Neau D, Galpérine T, Legrand E, Pitard V, Neau-Cransac M, Moreau JF, Ragnaud JM, Dupon M, Fleury H, Lafon ME.

HIV Med. 2003 Apr;4(2):120-6.


Flt3-ligand induces adhesion of haematopoietic progenitor cells via a very late antigen (VLA)-4- and VLA-5-dependent mechanism.

Solanilla A, Grosset C, Duchez P, Legembre P, Pitard V, Dupouy M, Belloc F, Viallard JF, Reiffers J, Boiron JM, Coulombel L, Ripoche J.

Br J Haematol. 2003 Mar;120(5):782-6.


CD4 T lymphocyte proliferative responses to hepatitis C virus (HCV) antigens in patients coinfected with HCV and human immunodeficiency virus who responded to anti-HCV treatment.

Legrand E, Neau D, Galperine T, Trimoulet P, Moreau JF, Pitard V, Lacut JY, Ragnaud JM, Dupon M, Le Bail B, Bernard N, Schvoerer E, Houghton M, Fleury H, Lafon ME.

J Infect Dis. 2002 Aug 1;186(3):302-11. Epub 2002 Jul 17.


Identification of agonistic and antagonistic antibodies against gp190, the leukemia inhibitory factor receptor, reveals distinct roles for its two cytokine-binding domains.

Taupin JL, Legembre P, Bitard J, Daburon S, Pitard V, Blanchard F, Duplomb L, Godard A, Jacques Y, Moreau JF.

J Biol Chem. 2001 Dec 21;276(51):47975-81. Epub 2001 Oct 17.


Stimulation of leukemia inhibitory factor receptor degradation by extracellular signal-regulated kinase.

Blanchard F, Duplomb L, Wang Y, Robledo O, Kinzie E, Pitard V, Godard A, Jacques Y, Baumann H.

J Biol Chem. 2000 Sep 15;275(37):28793-801.


Human gammadelta T cells and viruses.

Déchanet J, Merville P, Pitard V, Lafarge X, Moreau JF.

Microbes Infect. 1999 Mar;1(3):213-7. Review. No abstract available.


Different epitopes are required for gp130 activation by interleukin-6, oncostatin M and leukemia inhibitory factor.

Timmermann A, Pflanz S, Grötzinger J, Küster A, Kurth I, Pitard V, Heinrich PC, Müller-Newen G.

FEBS Lett. 2000 Feb 25;468(2-3):120-4.


Implication of gammadelta T cells in the human immune response to cytomegalovirus.

Déchanet J, Merville P, Lim A, Retière C, Pitard V, Lafarge X, Michelson S, Méric C, Hallet MM, Kourilsky P, Potaux L, Bonneville M, Moreau JF.

J Clin Invest. 1999 May 15;103(10):1437-49.


Binding of leukemia inhibitory factor (LIF) to mutants of its low affinity receptor, gp190, reveals a LIF binding site outside and interactions between the two cytokine binding domains.

Taupin JL, Miossec V, Pitard V, Blanchard F, Daburon S, Raher S, Jacques Y, Godard A, Moreau JF.

J Biol Chem. 1999 May 14;274(20):14482-9.


Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor.

Thiel S, Behrmann I, Timmermann A, Dahmen H, Müller-Newen G, Schaper F, Tavernier J, Pitard V, Heinrich PC, Graeve L.

Biochem J. 1999 Apr 1;339 ( Pt 1):15-9.


The presence in human serum of a circulating soluble leukemia inhibitory factor receptor (sgp190) and its evolution during pregnancy.

Pitard V, Lorgeot V, Taupin JL, Aubard Y, Praloran V, Moreau JF.

Eur Cytokine Netw. 1998 Dec;9(4):599-605.


The mannose 6-phosphate/insulin-like growth factor II receptor is a nanomolar affinity receptor for glycosylated human leukemia inhibitory factor.

Blanchard F, Raher S, Duplomb L, Vusio P, Pitard V, Taupin JL, Moreau JF, Hoflack B, Minvielle S, Jacques Y, Godard A.

J Biol Chem. 1998 Aug 14;273(33):20886-93.


Leukemia inhibitory factor: part of a large ingathering family.

Taupin JL, Pitard V, Dechanet J, Miossec V, Gualde N, Moreau JF.

Int Rev Immunol. 1998;16(3-4):397-426. Review.


Epitope-function relationships of human leukemia inhibitory factor receptors using a novel set of anti-gp190 mAB.

Blanchard F, Pitard V, Taupin JL, Raher S, Hallet MM, Moreau JF, Godard A, Jacques Y.

Int Immunol. 1997 Dec;9(12):1775-84.


Production and characterization of monoclonal antibodies against the leukemia inhibitory factor low affinity receptor, gp190.

Pitard V, Taupin JL, Miossec V, Blanchard F, Cransac M, Jollet I, Vernallis A, Hudson K, Godard A, Jacques Y, Moreau JF.

J Immunol Methods. 1997 Jul 14;205(2):177-90.


Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop.

Gu ZJ, Costes V, Lu ZY, Zhang XG, Pitard V, Moreau JF, Bataille R, Wijdenes J, Rossi JF, Klein B.

Blood. 1996 Nov 15;88(10):3972-86.


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