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Items: 37


Nicotinamide N-Methyltransferase Interacts with Enzymes of the Methionine Cycle and Regulates Methyl Donor Metabolism.

Hong S, Zhai B, Pissios P.

Biochemistry. 2018 Oct 9;57(40):5775-5779. doi: 10.1021/acs.biochem.8b00561. Epub 2018 Sep 24.


An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N-Methyltransferase Gene Expression.

Crujeiras AB, Pissios P, Moreno-Navarrete JM, Diaz-Lagares A, Sandoval J, Gomez A, Ricart W, Esteller M, Casanueva FF, Fernandez-Real JM.

Mol Nutr Food Res. 2018 Apr 24:e1700933. doi: 10.1002/mnfr.201700933. [Epub ahead of print]


Nicotinamide N-methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes.

Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-Navarrete JM, Fernandez-Real JM, Pissios P, Fraenkel PG.

Hepatol Commun. 2017 Sep 11;1(8):803-815. doi: 10.1002/hep4.1083. eCollection 2017 Oct.


TSHB mRNA is linked to cholesterol metabolism in adipose tissue.

Moreno-Navarrete JM, Moreno M, Ortega F, Xifra G, Hong S, Asara JM, Serrano JCE, Jové M, Pissios P, Blüher M, Ricart W, Portero-Otin M, Fernández-Real JM.

FASEB J. 2017 Oct;31(10):4482-4491. doi: 10.1096/fj.201700161R. Epub 2017 Jun 23.


Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production.

Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, Fisher FM, Pissios P, Withers DJ, Selman C, Wang R, Yen K, Longo VD, Cohen P, Bartke A, Kopchick JJ, Miller R, Hollenberg AN, Mitchell JR.

Cell Metab. 2017 Jun 6;25(6):1320-1333.e5. doi: 10.1016/j.cmet.2017.05.003.


Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme.

Pissios P.

Trends Endocrinol Metab. 2017 May;28(5):340-353. doi: 10.1016/j.tem.2017.02.004. Epub 2017 Mar 11. Review.


Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control.

Song W, Cheng D, Hong S, Sappe B, Hu Y, Wei N, Zhu C, O'Connor MB, Pissios P, Perrimon N.

Cell Metab. 2017 Feb 7;25(2):386-399. doi: 10.1016/j.cmet.2017.01.002.


Fibroblast growth factor 21 has no direct role in regulating fertility in female mice.

Singhal G, Douris N, Fish AJ, Zhang X, Adams AC, Flier JS, Pissios P, Maratos-Flier E.

Mol Metab. 2016 May 18;5(8):690-698. doi: 10.1016/j.molmet.2016.05.010. eCollection 2016 Aug.


Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet.

Douris N, Melman T, Pecherer JM, Pissios P, Flier JS, Cantley LC, Locasale JW, Maratos-Flier E.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2056-65. doi: 10.1016/j.bbadis.2015.07.009. Epub 2015 Jul 11.


Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.

Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P.

Nat Med. 2015 Aug;21(8):887-94. doi: 10.1038/nm.3882. Epub 2015 Jul 13.


Expression of melanin-concentrating hormone receptor 2 protects against diet-induced obesity in male mice.

Chee MJ, Pissios P, Prasad D, Maratos-Flier E.

Endocrinology. 2014 Jan;155(1):81-8. doi: 10.1210/en.2013-1738. Epub 2013 Dec 20.


Methionine and choline regulate the metabolic phenotype of a ketogenic diet.

Pissios P, Hong S, Kennedy AR, Prasad D, Liu FF, Maratos-Flier E.

Mol Metab. 2013 Jul 8;2(3):306-13. doi: 10.1016/j.molmet.2013.07.003. eCollection 2013.


Neurochemical characterization of neurons expressing melanin-concentrating hormone receptor 1 in the mouse hypothalamus.

Chee MJ, Pissios P, Maratos-Flier E.

J Comp Neurol. 2013 Jul 1;521(10):2208-34. doi: 10.1002/cne.23273.


Nicotinamide N-oxidation by CYP2E1 in human liver microsomes.

Real AM, Hong S, Pissios P.

Drug Metab Dispos. 2013 Mar;41(3):550-3. doi: 10.1124/dmd.112.049734. Epub 2012 Dec 21.


Ablation of the hypothalamic neuropeptide melanin concentrating hormone is associated with behavioral abnormalities that reflect impaired olfactory integration.

Adams AC, Domouzoglou EM, Chee MJ, Segal-Lieberman G, Pissios P, Maratos-Flier E.

Behav Brain Res. 2011 Oct 10;224(1):195-200. doi: 10.1016/j.bbr.2011.05.039. Epub 2011 Jun 6.


The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone.

Glier MB, Pissios P, Babich SL, Macdonald ML, Hayden MR, Maratos-Flier E, Gibson WT.

Peptides. 2010 Jan;31(1):123-9. doi: 10.1016/j.peptides.2009.10.018. Epub 2009 Oct 31.


A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss.

Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1197-204. doi: 10.1152/ajpendo.00357.2009. Epub 2009 Sep 8.


Animals models of MCH function and what they can tell us about its role in energy balance.

Pissios P.

Peptides. 2009 Nov;30(11):2040-4. doi: 10.1016/j.peptides.2009.05.002. Epub 2009 May 15. Review.


Dysregulation of the mesolimbic dopamine system and reward in MCH-/- mice.

Pissios P, Frank L, Kennedy AR, Porter DR, Marino FE, Liu FF, Pothos EN, Maratos-Flier E.

Biol Psychiatry. 2008 Aug 1;64(3):184-91. doi: 10.1016/j.biopsych.2007.12.011. Epub 2008 Feb 20.


More than satiety: central serotonin signaling and glucose homeostasis.

Pissios P, Maratos-Flier E.

Cell Metab. 2007 Nov;6(5):345-7.


Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states.

Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E.

Cell Metab. 2007 Jun;5(6):426-37.


A high-fat, ketogenic diet induces a unique metabolic state in mice.

Kennedy AR, Pissios P, Otu H, Roberson R, Xue B, Asakura K, Furukawa N, Marino FE, Liu FF, Kahn BB, Libermann TA, Maratos-Flier E.

Am J Physiol Endocrinol Metab. 2007 Jun;292(6):E1724-39. Epub 2007 Feb 13. Erratum in: Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1846. Roberson, Russell [added]. Am J Physiol Endocrinol Metab. 2009 May;296(5):E1179.


Xanthine oxidoreductase is a regulator of adipogenesis and PPARgamma activity.

Cheung KJ, Tzameli I, Pissios P, Rovira I, Gavrilova O, Ohtsubo T, Chen Z, Finkel T, Flier JS, Friedman JM.

Cell Metab. 2007 Feb;5(2):115-28.


Melanin concentrating hormone is a novel regulator of islet function and growth.

Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.

Diabetes. 2007 Feb;56(2):311-9.


Leptin regulation of the mesoaccumbens dopamine pathway.

Fulton S, Pissios P, Manchon RP, Stiles L, Frank L, Pothos EN, Maratos-Flier E, Flier JS.

Neuron. 2006 Sep 21;51(6):811-22.


Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions.

Pissios P, Bradley RL, Maratos-Flier E.

Endocr Rev. 2006 Oct;27(6):606-20. Epub 2006 Jun 20. Review.


MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance.

Jeon JY, Bradley RL, Kokkotou EG, Marino FE, Wang X, Pissios P, Maratos-Flier E.

Diabetes. 2006 Feb;55(2):428-34.


Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.

Gibson WT, Pissios P, Trombly DJ, Luan J, Keogh J, Wareham NJ, Maratos-Flier E, O'Rahilly S, Farooqi IS.

Obes Res. 2004 May;12(5):743-9.


Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways.

Pissios P, Trombly DJ, Tzameli I, Maratos-Flier E.

Endocrinology. 2003 Aug;144(8):3514-23.


Melanin-concentrating hormone: from fish skin to skinny mammals.

Pissios P, Maratos-Flier E.

Trends Endocrinol Metab. 2003 Jul;14(5):243-8. Review.


New insights into receptor ligand binding domains from a novel assembly assay.

Pissios P, Tzameli I, Moore DD.

J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):3-7. Review.


Dynamic stabilization of nuclear receptor ligand binding domains by hormone or corepressor binding.

Pissios P, Tzameli I, Kushner P, Moore DD.

Mol Cell. 2000 Aug;6(2):245-53.


Mitochondrial DNA evolution in the Montium-species subgroup of Drosophila.

Pissios P, Scouras ZG.

Mol Biol Evol. 1993 Mar;10(2):375-82.


Rapid isolation of mitochondrial DNA. Mitochondrial DNA from Drosophila serrata.

Pissios P, Scouras ZG.

Experientia. 1992 Jul 15;48(7):671-3.


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