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Items: 13


Fibroblast state switching orchestrates dermal maturation and wound healing.

Rognoni E, Pisco AO, Hiratsuka T, Sipilä KH, Belmonte JM, Mobasseri SA, Philippeos C, Dilão R, Watt FM.

Mol Syst Biol. 2018 Aug 29;14(8):e8174. doi: 10.15252/msb.20178174.


Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation.

Kober KI, Cano A, Géraud C, Sipilä K, Mobasseri SA, Philippeos C, Pisco AO, Stannard A, Martin A, Salvador F, Santos V, Boutros M, Rognoni E, Watt FM.

PLoS One. 2018 Jun 28;13(6):e0199679. doi: 10.1371/journal.pone.0199679. eCollection 2018.


An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.

Liakath-Ali K, Mills EW, Sequeira I, Lichtenberger BM, Pisco AO, Sipilä KH, Mishra A, Yoshikawa H, Wu CC, Ly T, Lamond AI, Adham IM, Green R, Watt FM.

Nature. 2018 Apr;556(7701):376-380. doi: 10.1038/s41586-018-0032-3. Epub 2018 Apr 11.


Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations.

Philippeos C, Telerman SB, Oulès B, Pisco AO, Shaw TJ, Elgueta R, Lombardi G, Driskell RR, Soldin M, Lynch MD, Watt FM.

J Invest Dermatol. 2018 Apr;138(4):811-825. doi: 10.1016/j.jid.2018.01.016. Epub 2018 Jan 31.


A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis.

Mishra A, Oulès B, Pisco AO, Ly T, Liakath-Ali K, Walko G, Viswanathan P, Tihy M, Nijjher J, Dunn SJ, Lamond AI, Watt FM.

Elife. 2017 Oct 18;6. pii: e27356. doi: 10.7554/eLife.27356.


Integration of Kinase and Calcium Signaling at the Level of Chromatin Underlies Inducible Gene Activation in T Cells.

Brignall R, Cauchy P, Bevington SL, Gorman B, Pisco AO, Bagnall J, Boddington C, Rowe W, England H, Rich K, Schmidt L, Dyer NP, Travis MA, Ott S, Jackson DA, Cockerill PN, Paszek P.

J Immunol. 2017 Oct 15;199(8):2652-2667. doi: 10.4049/jimmunol.1602033. Epub 2017 Sep 13.


Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth.

Telerman SB, Rognoni E, Sequeira I, Pisco AO, Lichtenberger BM, Culley OJ, Viswanathan P, Driskell RR, Watt FM.

J Invest Dermatol. 2017 Nov;137(11):2270-2281. doi: 10.1016/j.jid.2017.06.015. Epub 2017 Jun 28.


A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.

Walko G, Woodhouse S, Pisco AO, Rognoni E, Liakath-Ali K, Lichtenberger BM, Mishra A, Telerman SB, Viswanathan P, Logtenberg M, Renz LM, Donati G, Quist SR, Watt FM.

Nat Commun. 2017 Mar 23;8:14744. doi: 10.1038/ncomms14744.


Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing.

Rognoni E, Gomez C, Pisco AO, Rawlins EL, Simons BD, Watt FM, Driskell RR.

Development. 2016 Jul 15;143(14):2522-35. doi: 10.1242/dev.131797. Epub 2016 Jun 10.


Non-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: 'What does not kill me strengthens me'.

Pisco AO, Huang S.

Br J Cancer. 2015 May 26;112(11):1725-32. doi: 10.1038/bjc.2015.146. Epub 2015 May 12. Review.


Nonequilibrium population dynamics of phenotype conversion of cancer cells.

Zhou JX, Pisco AO, Qian H, Huang S.

PLoS One. 2014 Dec 1;9(12):e110714. doi: 10.1371/journal.pone.0110714. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0118133.


Reduced Intracellular Drug Accumulation in Drug-Resistant Leukemia Cells is Not Only Solely Due to MDR-Mediated Efflux but also to Decreased Uptake.

Pisco AO, Jackson DA, Huang S.

Front Oncol. 2014 Oct 31;4:306. doi: 10.3389/fonc.2014.00306. eCollection 2014.


Non-Darwinian dynamics in therapy-induced cancer drug resistance.

Pisco AO, Brock A, Zhou J, Moor A, Mojtahedi M, Jackson D, Huang S.

Nat Commun. 2013;4:2467. doi: 10.1038/ncomms3467.

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