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Items: 1 to 50 of 95

1.

Synthesis and bioluminescence of thioluciferin.

Pirrung MC, Carlson AD, De Howitt N, Liao J.

Bioorg Med Chem Lett. 2019 Oct 1;29(19):126591. doi: 10.1016/j.bmcl.2019.07.050. Epub 2019 Jul 29.

PMID:
31471166
2.

ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries.

Colby SM, Thomas DG, Nuñez JR, Baxter DJ, Glaesemann KR, Brown JM, Pirrung MA, Govind N, Teeguarden JG, Metz TO, Renslow RS.

Anal Chem. 2019 Apr 2;91(7):4346-4356. doi: 10.1021/acs.analchem.8b04567. Epub 2019 Mar 6.

PMID:
30741529
3.

Thiasyrbactins Induce Cell Death via Proteasome Inhibition in Multiple Myeloma Cells.

Pierce MR, Bakas NA, Pirrung MC, Bachmann AS.

Anticancer Res. 2018 Oct;38(10):5607-5613. doi: 10.21873/anticanres.12895.

4.

Immunoproteasome inhibition and bioactivity of thiasyrbactins.

Bakas NA, Schultz CR, Yco LP, Roberts CC, Chang CA, Bachmann AS, Pirrung MC.

Bioorg Med Chem. 2018 Jan 15;26(2):401-412. doi: 10.1016/j.bmc.2017.11.048. Epub 2017 Dec 7.

5.

β-Deuterium Isotope Effects on Firefly Luciferase Bioluminescence.

Pirrung MC, Dorsey A, Howitt N, Liao J.

ChemistryOpen. 2017 Sep 6;6(6):697-700. doi: 10.1002/open.201700136. eCollection 2017 Dec.

6.

FQC Dashboard: integrates FastQC results into a web-based, interactive, and extensible FASTQ quality control tool.

Brown J, Pirrung M, McCue LA.

Bioinformatics. 2017 Jun 9. doi: 10.1093/bioinformatics/btx373. [Epub ahead of print]

7.

Native Serine Peptide Assembly: Scope and Utility.

Pirrung MC, Schreihans RS.

European J Org Chem. 2016 Dec;2016(34):5633-5636. doi: 10.1002/ejoc.201601148. Epub 2016 Nov 15.

8.

Correction: Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation.

Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y.

Org Biomol Chem. 2016 Sep 26;14(38):9159.

PMID:
27714303
9.

Total synthesis of fellutamides, lipopeptide proteasome inhibitors. More sustainable peptide bond formation.

Pirrung MC, Zhang F, Ambadi S, Gangadhara Rao Y.

Org Biomol Chem. 2016 Sep 21;14(35):8367-75. doi: 10.1039/c6ob01233g. Epub 2016 Aug 17. Erratum in: Org Biomol Chem. 2016 Sep 26;14(38):9159.

10.

Syrbactin Structural Analog TIR-199 Blocks Proteasome Activity and Induces Tumor Cell Death.

Bachmann AS, Opoku-Ansah J, Ibarra-Rivera TR, Yco LP, Ambadi S, Roberts CC, Chang CE, Pirrung MC.

J Biol Chem. 2016 Apr 15;291(16):8350-62. doi: 10.1074/jbc.M115.710053. Epub 2016 Feb 23.

11.

Identifying novel sequence variants of RNA 3D motifs.

Zirbel CL, Roll J, Sweeney BA, Petrov AI, Pirrung M, Leontis NB.

Nucleic Acids Res. 2015 Sep 3;43(15):7504-20. doi: 10.1093/nar/gkv651. Epub 2015 Jun 29.

12.

Incontinence in children with autism spectrum disorder.

von Gontard A, Pirrung M, Niemczyk J, Equit M.

J Pediatr Urol. 2015 Oct;11(5):264.e1-7. doi: 10.1016/j.jpurol.2015.04.015. Epub 2015 May 22.

PMID:
26052001
13.

Bacteria from diverse habitats colonize and compete in the mouse gut.

Seedorf H, Griffin NW, Ridaura VK, Reyes A, Cheng J, Rey FE, Smith MI, Simon GM, Scheffrahn RH, Woebken D, Spormann AM, Van Treuren W, Ursell LK, Pirrung M, Robbins-Pianka A, Cantarel BL, Lombard V, Henrissat B, Knight R, Gordon JI.

Cell. 2014 Oct 9;159(2):253-66. doi: 10.1016/j.cell.2014.09.008. Epub 2014 Oct 2.

14.

Synthesis and bioluminescence of difluoroluciferin.

Pirrung MC, Biswas G, De Howitt N, Liao J.

Bioorg Med Chem Lett. 2014 Oct 15;24(20):4881-3. doi: 10.1016/j.bmcl.2014.08.048. Epub 2014 Aug 28.

PMID:
25239851
15.

The genesis of microarrays.

Pirrung MC, Southern EM.

Biochem Mol Biol Educ. 2014 Mar-Apr;42(2):106-13. doi: 10.1002/bmb.20756. Epub 2013 Dec 17. Review.

16.

EMPeror: a tool for visualizing high-throughput microbial community data.

Vázquez-Baeza Y, Pirrung M, Gonzalez A, Knight R.

Gigascience. 2013 Nov 26;2(1):16. doi: 10.1186/2047-217X-2-16.

17.

Catalyzed Claisen rearrangements of O-allyl kojates.

Pirrung MC, Nalbandian JN.

Tetrahedron Lett. 2013 Jul 17;54(29). doi: 10.1016/j.tetlet.2013.05.002.

18.

Replenishing our defensive microbes.

Ursell LK, Van Treuren W, Metcalf JL, Pirrung M, Gewirtz A, Knight R.

Bioessays. 2013 Sep;35(9):810-7. doi: 10.1002/bies.201300018. Epub 2013 Jul 8. Review.

19.

Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.

Thomas S, Sharma N, Gonzalez R, Pao PW, Hofman FM, Chen TC, Louie SG, Pirrung MC, Schönthal AH.

PLoS One. 2013 Jun 6;8(6):e65695. doi: 10.1371/journal.pone.0065695. Print 2013.

20.

Phylotastic! Making tree-of-life knowledge accessible, reusable and convenient.

Stoltzfus A, Lapp H, Matasci N, Deus H, Sidlauskas B, Zmasek CM, Vaidya G, Pontelli E, Cranston K, Vos R, Webb CO, Harmon LJ, Pirrung M, O'Meara B, Pennell MW, Mirarab S, Rosenberg MS, Balhoff JP, Bik HM, Heath TA, Midford PE, Brown JW, McTavish EJ, Sukumaran J, Westneat M, Alfaro ME, Steele A, Jordan G.

BMC Bioinformatics. 2013 May 13;14:158. doi: 10.1186/1471-2105-14-158.

21.

Evidence for a persistent microbial seed bank throughout the global ocean.

Gibbons SM, Caporaso JG, Pirrung M, Field D, Knight R, Gilbert JA.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4651-5. doi: 10.1073/pnas.1217767110. Epub 2013 Mar 4.

22.

A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays.

Zhao Y, Pirrung MC, Liao J.

Mol Biosyst. 2012 Mar;8(3):879-87. doi: 10.1039/c2mb05471j. Epub 2012 Jan 13.

PMID:
22241083
23.

Syringolin B-inspired proteasome inhibitor analogue TIR-203 exhibits enhanced biological activity in multiple myeloma and neuroblastoma.

Opoku-Ansah J, Ibarra-Rivera TR, Pirrung MC, Bachmann AS.

Pharm Biol. 2012 Jan;50(1):25-9. doi: 10.3109/13880209.2011.626784.

PMID:
22196580
24.

TopiaryExplorer: visualizing large phylogenetic trees with environmental metadata.

Pirrung M, Kennedy R, Caporaso JG, Stombaugh J, Wendel D, Knight R.

Bioinformatics. 2011 Nov 1;27(21):3067-9. doi: 10.1093/bioinformatics/btr517. Epub 2011 Sep 8.

25.

Novel proteasome-inhibitory syrbactin analogs inducing endoplasmic reticulum stress and apoptosis in hematological tumor cell lines.

Anshu A, Thomas S, Agarwal P, Ibarra-Rivera TR, Pirrung MC, Schönthal AH.

Biochem Pharmacol. 2011 Sep 15;82(6):600-9. doi: 10.1016/j.bcp.2011.06.031. Epub 2011 Jun 28.

PMID:
21736873
26.

Sensitized two-photon photochemical deprotection.

Pirrung MC, Dore TM, Zhu Y, Rana VS.

Chem Commun (Camb). 2010 Aug 7;46(29):5313-5. doi: 10.1039/c0cc00782j. Epub 2010 Jun 16.

PMID:
20552130
27.

Total synthesis of syringolin A and B.

Pirrung MC, Biswas G, Ibarra-Rivera TR.

Org Lett. 2010 May 21;12(10):2402-5. doi: 10.1021/ol100761z.

PMID:
20426399
28.

QIIME allows analysis of high-throughput community sequencing data.

Caporaso JG, Kuczynski J, Stombaugh J, Bittinger K, Bushman FD, Costello EK, Fierer N, Peña AG, Goodrich JK, Gordon JI, Huttley GA, Kelley ST, Knights D, Koenig JE, Ley RE, Lozupone CA, McDonald D, Muegge BD, Pirrung M, Reeder J, Sevinsky JR, Turnbaugh PJ, Walters WA, Widmann J, Yatsunenko T, Zaneveld J, Knight R.

Nat Methods. 2010 May;7(5):335-6. doi: 10.1038/nmeth.f.303. Epub 2010 Apr 11. No abstract available.

29.

His-tags lighten up and lose their inhibitions.

Pirrung MC.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6123-4. doi: 10.1073/pnas.1002011107. Epub 2010 Apr 2. No abstract available.

30.

Iodine scanning of a phenazine inhibitor of vacuolar sorting.

Surpin M, Zou Y, Xiong C, Raikhel NV, Pirrung MC.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1496-9. doi: 10.1016/j.bmcl.2010.01.106. Epub 2010 Jan 25.

PMID:
20153185
31.

Multicomponent reactions of convertible isonitriles.

Pirrung MC, Ghorai S, Ibarra-Rivera TR.

J Org Chem. 2009 Jun 5;74(11):4110-7. doi: 10.1021/jo900414n.

PMID:
19408909
32.

Multicomponent reactions of cyclobutanones.

Pirrung MC, Wang J.

J Org Chem. 2009 Apr 17;74(8):2958-63. doi: 10.1021/jo802170k.

PMID:
19354324
33.

Small molecule activators of the Trk receptors for neuroprotection.

Webster NJ, Pirrung MC.

BMC Neurosci. 2008 Dec 3;9 Suppl 2:S1. doi: 10.1186/1471-2202-9-S2-S1. Review.

34.

Hydrophobicity and mixing effects on select heterogeneous, water-accelerated synthetic reactions.

Pirrung MC, Das Sarma K, Wang J.

J Org Chem. 2008 Nov 21;73(22):8723-30. doi: 10.1021/jo801134r. Epub 2008 Oct 28.

PMID:
18954111
35.

Ethylene receptor antagonists: strained alkenes are necessary but not sufficient.

Pirrung MC, Bleecker AB, Inoue Y, Rodríguez FI, Sugawara N, Wada T, Zou Y, Binder BM.

Chem Biol. 2008 Apr;15(4):313-21. doi: 10.1016/j.chembiol.2008.02.018.

36.

Preparation of methyl ester precursors of biologically active agents.

Zou Y, Rojas-Pierce M, Raikhel N, Pirrung M.

Biotechniques. 2008 Mar;44(3):377-84. doi: 10.2144/000112704.

37.

Modular synthesis of candidate indole-based insulin mimics by Claisen rearrangement.

Xiong X, Pirrung MC.

Org Lett. 2008 Mar 20;10(6):1151-4. doi: 10.1021/ol800058d. Epub 2008 Feb 28.

PMID:
18303898
38.

Quinone replacements for small molecule insulin mimics.

Pirrung MC, Deng L, Lin B, Webster NJ.

Chembiochem. 2008 Feb 15;9(3):360-2. doi: 10.1002/cbic.200700597. No abstract available.

39.

Identification of novel orally available small molecule insulin mimetics.

Lin B, Li Z, Park K, Deng L, Pai A, Zhong L, Pirrung MC, Webster NJ.

J Pharmacol Exp Ther. 2007 Nov;323(2):579-85. Epub 2007 Aug 8.

PMID:
17687071
40.

Parallel synthesis of indolylquinones and their cell-based insulin mimicry.

Pirrung MC, Li Z, Hensley E, Liu Y, Tanksale A, Lin B, Pai A, Webster NJ.

J Comb Chem. 2007 Sep-Oct;9(5):844-54. Epub 2007 Jun 27.

PMID:
17595147
41.

Glyceraldehyde 3-phosphate dehydrogenase is a cellular target of the insulin mimic demethylasterriquinone B1.

Kim H, Deng L, Xiong X, Hunter WD, Long MC, Pirrung MC.

J Med Chem. 2007 Jul 26;50(15):3423-6. Epub 2007 Jun 27.

42.

Practical synthesis of 7-prenylindole.

Xiong X, Pirrung MC.

J Org Chem. 2007 Jul 20;72(15):5832-4. Epub 2007 Jun 20.

43.

Neuroprotection by small molecule activators of the nerve growth factor receptor.

Lin B, Pirrung MC, Deng L, Li Z, Liu Y, Webster NJ.

J Pharmacol Exp Ther. 2007 Jul;322(1):59-69. Epub 2007 Apr 27.

PMID:
17468299
44.

Versatile, fragrant, convertible isonitriles.

Pirrung MC, Ghorai S.

J Am Chem Soc. 2006 Sep 13;128(36):11772-3.

PMID:
16953613
45.

Mechanistic studies on the photochemical deprotection of 3',5'-dimethoxybenzoin esters.

Pirrung MC, Ye T, Zhou Z, Simon JD.

Photochem Photobiol. 2006 Sep-Oct;82(5):1258-64.

PMID:
16752957
46.

Molecular validation of LpxC as an antibacterial drug target in Pseudomonas aeruginosa.

Mdluli KE, Witte PR, Kline T, Barb AW, Erwin AL, Mansfield BE, McClerren AL, Pirrung MC, Tumey LN, Warrener P, Raetz CR, Stover CK.

Antimicrob Agents Chemother. 2006 Jun;50(6):2178-84.

47.

Acceleration of organic reactions through aqueous solvent effects.

Pirrung MC.

Chemistry. 2006 Feb 1;12(5):1312-7.

PMID:
16189838
48.

Adding precision tools to the plant biologists' toolbox with chemical genomics.

Raikhel N, Pirrung M.

Plant Physiol. 2005 Jun;138(2):563-4. Review. No abstract available.

49.

Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents.

Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER.

J Med Chem. 2005 Apr 21;48(8):3045-50.

PMID:
15828843
50.

Methyl scanning: total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s).

Pirrung MC, Liu Y, Deng L, Halstead DK, Li Z, May JF, Wedel M, Austin DA, Webster NJ.

J Am Chem Soc. 2005 Apr 6;127(13):4609-24.

PMID:
15796526

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