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Items: 1 to 50 of 63

1.

GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects.

Desai A, Sowerwine K, Liu Y, Lawrence MG, Chovanec J, Hsu AP, O'Connell MP, Kim J, Boris L, Jones N, Wisch L, Eisch RR, Carter MC, Komarow HD, Zerbe C, Milner JD, Maric I, Sun X, Lee CR, Tunc I, Pirooznia M, Stone KD, Holland SM, Metcalfe DD, Lyons JJ.

J Allergy Clin Immunol. 2019 May 15. pii: S0091-6749(19)30624-4. doi: 10.1016/j.jaci.2019.05.007. [Epub ahead of print] No abstract available.

PMID:
31102699
2.

Circulating Lymphangioleiomyomatosis Tumor Cells With Loss of Heterozygosity in the TSC2 Gene Show Increased Aldehyde Dehydrogenase Activity.

Pacheco-Rodríguez G, Steagall WK, Samsel L, Dagur PK, McCoy JP, Tunc I, Pirooznia M, Wang JA, Darling TN, Moss J.

Chest. 2019 Apr 26. pii: S0012-3692(19)30874-8. doi: 10.1016/j.chest.2019.03.040. [Epub ahead of print]

PMID:
31034819
3.

Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis.

Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, Baumer Y, Harrington CL, Stempinski E, Elnabawi YA, Dagur PK, Cui K, Tunc I, Seifuddin F, Joshi AA, Stansky E, Purmalek MM, Rodante JA, Keel A, Aridi TZ, Carmona-Rivera C, Sanda GE, Chen MY, Pirooznia M, McCoy JP Jr, Gelfand JM, Zhao K, Gudjonsson JE, Playford MP, Kaplan MJ, Berger JS, Mehta NN.

JACC Basic Transl Sci. 2019 Feb 25;4(1):1-14. doi: 10.1016/j.jacbts.2018.10.008. eCollection 2019 Feb.

4.

Ancient Ancestry Informative Markers for Identifying Fine-Scale Ancient Population Structure in Eurasians.

Esposito U, Das R, Syed S, Pirooznia M, Elhaik E.

Genes (Basel). 2018 Dec 12;9(12). pii: E625. doi: 10.3390/genes9120625.

5.

Pathogenic TERT promoter variants in telomere diseases.

Gutierrez-Rodrigues F, Donaires FS, Pinto A, Vicente A, Dillon LW, Clé DV, Santana BA, Pirooznia M, Ibanez MDPF, Townsley DM, Kajigaya S, Hourigan CS, Cooper JN, Calado RT, Young NS.

Genet Med. 2018 Dec 7. doi: 10.1038/s41436-018-0385-x. [Epub ahead of print]

6.

The transcription factors TFE3 and TFEB amplify p53 dependent transcriptional programs in response to DNA damage.

Brady OA, Jeong E, Martina JA, Pirooznia M, Tunc I, Puertollano R.

Elife. 2018 Dec 6;7. pii: e40856. doi: 10.7554/eLife.40856.

7.

Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa.

Povoleri GAM, Nova-Lamperti E, Scottà C, Fanelli G, Chen YC, Becker PD, Boardman D, Costantini B, Romano M, Pavlidis P, McGregor R, Pantazi E, Chauss D, Sun HW, Shih HY, Cousins DJ, Cooper N, Powell N, Kemper C, Pirooznia M, Laurence A, Kordasti S, Kazemian M, Lombardi G, Afzali B.

Nat Immunol. 2018 Dec;19(12):1403-1414. doi: 10.1038/s41590-018-0230-z. Epub 2018 Nov 5.

8.

High density lipoprotein proteome is associated with cardiovascular risk factors and atherosclerosis burden as evaluated by coronary CT angiography.

Gordon SM, Chung JH, Playford MP, Dey AK, Sviridov D, Seifuddin F, Chen YC, Pirooznia M, Chen MY, Mehta NN, Remaley AT.

Atherosclerosis. 2018 Nov;278:278-285. doi: 10.1016/j.atherosclerosis.2018.09.032. Epub 2018 Sep 25.

PMID:
30347343
9.

GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking.

Wu K, Wang L, Chen Y, Pirooznia M, Singh K, Wälde S, Kehlenbach RH, Scott I, Gucek M, Sack MN.

J Cell Sci. 2018 Nov 20;131(22). pii: jcs221036. doi: 10.1242/jcs.221036.

10.

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.

Arbore G, West EE, Rahman J, Le Friec G, Niyonzima N, Pirooznia M, Tunc I, Pavlidis P, Powell N, Li Y, Liu P, Servais A, Couzi L, Fremeaux-Bacchi V, Placais L, Ferraro A, Walsh PR, Kavanagh D, Afzali B, Lavender P, Lachmann HJ, Kemper C.

Nat Commun. 2018 Oct 10;9(1):4186. doi: 10.1038/s41467-018-06706-z.

11.

Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia.

Dillon LW, Hayati S, Roloff GW, Tunc I, Pirooznia M, Mitrofanova A, Hourigan CS.

Haematologica. 2019 Feb;104(2):297-304. doi: 10.3324/haematol.2018.203133. Epub 2018 Aug 31.

12.

Circulating cell-free DNA as a biomarker of tissue injury: Assessment in a cardiac xenotransplantation model.

Agbor-Enoh S, Chan JL, Singh A, Tunc I, Gorham S, Zhu J, Pirooznia M, Corcoran PC, Thomas ML, Lewis BGT, Jang MK, Ayares DL, Horvath KA, Mohiuddin MM, Valantine H.

J Heart Lung Transplant. 2018 Aug;37(8):967-975. doi: 10.1016/j.healun.2018.04.009. Epub 2018 Apr 26.

PMID:
29933912
13.

Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

Tamura K, Yu J, Hata T, Suenaga M, Shindo K, Abe T, MacGregor-Das A, Borges M, Wolfgang CL, Weiss MJ, He J, Canto MI, Petersen GM, Gallinger S, Syngal S, Brand RE, Rustgi A, Olson SH, Stoffel E, Cote ML, Zogopoulos G, Potash JB, Goes FS, McCombie RW, Zandi PP, Pirooznia M, Kramer M, Parla J, Eshleman JR, Roberts NJ, Hruban RH, Klein AP, Goggins M.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4767-4772. doi: 10.1073/pnas.1720588115. Epub 2018 Apr 18.

14.

Late manifestation of alloantibody-associated injury and clinical pulmonary antibody-mediated rejection: Evidence from cell-free DNA analysis.

Agbor-Enoh S, Jackson AM, Tunc I, Berry GJ, Cochrane A, Grimm D, Davis A, Shah P, Brown AW, Wang Y, Timofte I, Shah P, Gorham S, Wylie J, Goodwin N, Jang MK, Marishta A, Bhatti K, Fideli U, Yang Y, Luikart H, Cao Z, Pirooznia M, Zhu J, Marboe C, Iacono A, Nathan SD, Orens J, Valantine HA, Khush K.

J Heart Lung Transplant. 2018 Jul;37(7):925-932. doi: 10.1016/j.healun.2018.01.1305. Epub 2018 Jan 31.

PMID:
29500138
15.

The Diversity of REcent and Ancient huMan (DREAM): A New Microarray for Genetic Anthropology and Genealogy, Forensics, and Personalized Medicine.

Elhaik E, Yusuf L, Anderson AIJ, Pirooznia M, Arnellos D, Vilshansky G, Ercal G, Lu Y, Webster T, Baird ML, Esposito U.

Genome Biol Evol. 2017 Dec 1;9(12):3225-3237. doi: 10.1093/gbe/evx237.

16.

Assessment of Whole-Exome Sequence Data in Attempted Suicide within a Bipolar Disorder Cohort.

Monson ET, Pirooznia M, Parla J, Kramer M, Goes FS, Gaine ME, Gaynor SC, de Klerk K, Jancic D, Karchin R, McCombie WR, Zandi PP, Potash JB, Willour VL.

Mol Neuropsychiatry. 2017 Jul;3(1):1-11. doi: 10.1159/000454773. Epub 2017 Jan 18.

17.

The Origins of Ashkenaz, Ashkenazic Jews, and Yiddish.

Das R, Wexler P, Pirooznia M, Elhaik E.

Front Genet. 2017 Jun 21;8:87. doi: 10.3389/fgene.2017.00087. eCollection 2017.

18.

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.

Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, Jones DT, Sundaram L, Bhat RR, Li X, Pal LR, Kundu K, Yin Y, Moult J, Jiang Y, Pejaver V, Pagel KA, Li B, Mooney SD, Radivojac P, Shah S, Carraro M, Gasparini A, Leonardi E, Giollo M, Ferrari C, Tosatto SCE, Bachar E, Azaria JR, Ofran Y, Unger R, Niroula A, Vihinen M, Chang B, Wang MH, Franke A, Petersen BS, Pirooznia M, Zandi P, McCombie R, Potash JB, Altman RB, Klein TE, Hoskins RA, Repo S, Brenner SE, Morgan AA.

Hum Mutat. 2017 Sep;38(9):1182-1192. doi: 10.1002/humu.23280. Epub 2017 Jul 7.

19.

Genome-wide Methyl-Seq analysis of blood-brain targets of glucocorticoid exposure.

Seifuddin F, Wand G, Cox O, Pirooznia M, Moody L, Yang X, Tai J, Boersma G, Tamashiro K, Zandi P, Lee R.

Epigenetics. 2017 Aug;12(8):637-652. doi: 10.1080/15592294.2017.1334025. Epub 2017 May 30.

20.

Functional Genomics, Genetics, and Bioinformatics 2016.

Deng Y, Wang H, Hamamoto R, Duan S, Pirooznia M, Bai Y.

Biomed Res Int. 2016;2016:2625831. Epub 2016 Nov 22. No abstract available.

21.

Reconstructing Druze population history.

Marshall S, Das R, Pirooznia M, Elhaik E.

Sci Rep. 2016 Nov 16;6:35837. doi: 10.1038/srep35837.

22.

DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling.

Martin PM, Stanley RE, Ross AP, Freitas AE, Moyer CE, Brumback AC, Iafrati J, Stapornwongkul KS, Dominguez S, Kivimäe S, Mulligan KA, Pirooznia M, McCombie WR, Potash JB, Zandi PP, Purcell SM, Sanders SJ, Zuo Y, Sohal VS, Cheyette BNR.

Mol Psychiatry. 2018 Feb;23(2):467-475. doi: 10.1038/mp.2016.184. Epub 2016 Oct 18.

23.

Exome Sequencing of Familial Bipolar Disorder.

Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, Chen YC, Monson ET, Willour VL, Karchin R, Flickinger M, Locke AE, Levy SE, Scott LJ, Boehnke M, Stahl E, Moran JL, Hultman CM, Landén M, Purcell SM, Sklar P, Zandi PP, McCombie WR, Potash JB.

JAMA Psychiatry. 2016 Jun 1;73(6):590-7. doi: 10.1001/jamapsychiatry.2016.0251.

24.

Genome-wide DNA hydroxymethylation identifies potassium channels in the nucleus accumbens as discriminators of methamphetamine addiction and abstinence.

Cadet JL, Brannock C, Krasnova IN, Jayanthi S, Ladenheim B, McCoy MT, Walther D, Godino A, Pirooznia M, Lee RS.

Mol Psychiatry. 2017 Aug;22(8):1196-1204. doi: 10.1038/mp.2016.48. Epub 2016 Apr 5.

PMID:
27046646
25.

Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers.

Chen H, Liu H, Zou H, Chen R, Dou Y, Sheng S, Dai S, Ai J, Melson J, Kittles RA, Pirooznia M, Liptay MJ, Borgia JA, Deng Y.

J Cancer. 2016 Feb 5;7(5):490-9. doi: 10.7150/jca.12351. eCollection 2016.

26.

Localizing Ashkenazic Jews to Primeval Villages in the Ancient Iranian Lands of Ashkenaz.

Das R, Wexler P, Pirooznia M, Elhaik E.

Genome Biol Evol. 2016 Apr 19;8(4):1132-49. doi: 10.1093/gbe/evw046.

27.

Polygenic Risk of Schizophrenia and Cognition in a Population-Based Survey of Older Adults.

Liebers DT, Pirooznia M, Seiffudin F, Musliner KL, Zandi PP, Goes FS.

Schizophr Bull. 2016 Jul;42(4):984-91. doi: 10.1093/schbul/sbw001. Epub 2016 Feb 12.

28.

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer.

Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel E, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, Chaffee KG, Chen YC, Cote ML, Childs EJ, Douville C, Goes FS, Herman JM, Iacobuzio-Donahue C, Kramer M, Makohon-Moore A, McCombie RW, McMahon KW, Niknafs N, Parla J, Pirooznia M, Potash JB, Rhim AD, Smith AL, Wang Y, Wolfgang CL, Wood LD, Zandi PP, Goggins M, Karchin R, Eshleman JR, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH, Klein AP.

Cancer Discov. 2016 Feb;6(2):166-75. doi: 10.1158/2159-8290.CD-15-0402. Epub 2015 Dec 9.

29.

High-throughput sequencing of the synaptome in major depressive disorder.

Pirooznia M, Wang T, Avramopoulos D, Potash JB, Zandi PP, Goes FS.

Mol Psychiatry. 2016 May;21(5):650-5. doi: 10.1038/mp.2015.98. Epub 2015 Jul 28.

30.

Genome-wide association study of schizophrenia in Ashkenazi Jews.

Goes FS, McGrath J, Avramopoulos D, Wolyniec P, Pirooznia M, Ruczinski I, Nestadt G, Kenny EE, Vacic V, Peters I, Lencz T, Darvasi A, Mulle JG, Warren ST, Pulver AE.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):649-59. doi: 10.1002/ajmg.b.32349. Epub 2015 Jul 21.

PMID:
26198764
31.

Search for common targets of lithium and valproic acid identifies novel epigenetic effects of lithium on the rat leptin receptor gene.

Lee RS, Pirooznia M, Guintivano J, Ly M, Ewald ER, Tamashiro KL, Gould TD, Moran TH, Potash JB.

Transl Psychiatry. 2015 Jul 14;5:e600. doi: 10.1038/tp.2015.90.

32.

Whole-genome CNV analysis: advances in computational approaches.

Pirooznia M, Goes FS, Zandi PP.

Front Genet. 2015 Apr 13;6:138. doi: 10.3389/fgene.2015.00138. eCollection 2015. Review.

33.

Distinguishing bipolar from unipolar depression: the importance of clinical symptoms and illness features.

Leonpacher AK, Liebers D, Pirooznia M, Jancic D, MacKinnon DF, Mondimore FM, Schweizer B, Potash JB, Zandi PP; NIMH Genetics Initiative Bipolar Disorder Consortium, Goes FS.

Psychol Med. 2015 Aug;45(11):2437-46. doi: 10.1017/S0033291715000446. Epub 2015 Apr 8.

34.

Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis.

Musliner KL, Seifuddin F, Judy JA, Pirooznia M, Goes FS, Zandi PP.

Psychol Med. 2015 Jun;45(8):1709-20. doi: 10.1017/S0033291714002839. Epub 2014 Dec 9.

35.

Validation and assessment of variant calling pipelines for next-generation sequencing.

Pirooznia M, Kramer M, Parla J, Goes FS, Potash JB, McCombie WR, Zandi PP.

Hum Genomics. 2014 Jul 30;8:14. doi: 10.1186/1479-7364-8-14.

36.

Metamoodics: meta-analysis and bioinformatics resource for mood disorders.

Pirooznia M, Seifuddin F, Judy J, Goes FS, Potash JB, Zandi PP.

Mol Psychiatry. 2014 Jul;19(7):748-9. doi: 10.1038/mp.2013.118. Epub 2013 Sep 10. No abstract available.

37.

Systematic review of genome-wide gene expression studies of bipolar disorder.

Seifuddin F, Pirooznia M, Judy JT, Goes FS, Potash JB, Zandi PP.

BMC Psychiatry. 2013 Aug 15;13:213. doi: 10.1186/1471-244X-13-213. Review.

38.

Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder.

Judy JT, Seifuddin F, Pirooznia M, Mahon PB; Bipolar Genome Study Consortium, Jancic D, Goes FS, Schulze T, Cichon S, Noethen M, Rietschel M, Depaulo JR Jr, Potash JB, Zandi PP.

Front Genet. 2013 May 17;4:87. doi: 10.3389/fgene.2013.00087. eCollection 2013.

39.

SVAw - a web-based application tool for automated surrogate variable analysis of gene expression studies.

Pirooznia M, Seifuddin F, Goes FS, Leek JT, Zandi PP.

Source Code Biol Med. 2013 Mar 11;8(1):8. doi: 10.1186/1751-0473-8-8.

40.

A hybrid likelihood model for sequence-based disease association studies.

Chen YC, Carter H, Parla J, Kramer M, Goes FS, Pirooznia M, Zandi PP, McCombie WR, Potash JB, Karchin R.

PLoS Genet. 2013;9(1):e1003224. doi: 10.1371/journal.pgen.1003224. Epub 2013 Jan 24.

41.

Genome-wide association of mood-incongruent psychotic bipolar disorder.

Goes FS, Hamshere ML, Seifuddin F, Pirooznia M, Belmonte-Mahon P, Breuer R, Schulze T, Nöthen M, Cichon S, Rietschel M, Holmans P, Zandi PP; Bipolar Genome Study (BiGS), Craddock N, Potash JB.

Transl Psychiatry. 2012 Oct 23;2:e180. doi: 10.1038/tp.2012.106.

42.

Meta-analysis of genetic association studies on bipolar disorder.

Seifuddin F, Mahon PB, Judy J, Pirooznia M, Jancic D, Taylor J, Goes FS, Potash JB, Zandi PP.

Am J Med Genet B Neuropsychiatr Genet. 2012 Jul;159B(5):508-18. doi: 10.1002/ajmg.b.32057. Epub 2012 May 9.

43.

Genomic signatures and gene networking: challenges and promises.

Zhang K, Pirooznia M, Arabnia HR, Yang JY, Wang L, Luo Z, Deng Y.

BMC Genomics. 2011 Dec 23;12 Suppl 5:I1. doi: 10.1186/1471-2164-12-S5-I1. Epub 2011 Dec 23.

44.

SynaptomeDB: an ontology-based knowledgebase for synaptic genes.

Pirooznia M, Wang T, Avramopoulos D, Valle D, Thomas G, Huganir RL, Goes FS, Potash JB, Zandi PP.

Bioinformatics. 2012 Mar 15;28(6):897-9. doi: 10.1093/bioinformatics/bts040. Epub 2012 Jan 27.

45.

Gene expression analysis of CL-20-induced reversible neurotoxicity reveals GABA(A) receptors as potential targets in the earthworm Eisenia fetida.

Gong P, Guan X, Pirooznia M, Liang C, Perkins EJ.

Environ Sci Technol. 2012 Jan 17;46(2):1223-32. doi: 10.1021/es203642e. Epub 2012 Jan 6.

46.

Data mining approaches for genome-wide association of mood disorders.

Pirooznia M, Seifuddin F, Judy J, Mahon PB; Bipolar Genome Study (BiGS) Consortium, Potash JB, Zandi PP.

Psychiatr Genet. 2012 Apr;22(2):55-61. doi: 10.1097/YPG.0b013e32834dc40d.

47.

Conserved toxic responses across divergent phylogenetic lineages: a meta-analysis of the neurotoxic effects of RDX among multiple species using toxicogenomics.

Garcia-Reyero N, Habib T, Pirooznia M, Gust KA, Gong P, Warner C, Wilbanks M, Perkins E.

Ecotoxicology. 2011 May;20(3):580-94. doi: 10.1007/s10646-011-0623-3. Epub 2011 Mar 29.

PMID:
21516383
48.

A genome-wide association study of attempted suicide.

Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF; Bipolar Genome Study Consortium, Perlis RH, Lee PH, Huang J, Kelsoe JR, Shilling PD, Rietschel M, Nöthen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, DePaulo JR Jr, Schulze TG, McMahon FJ, Zandi PP, Potash JB.

Mol Psychiatry. 2012 Apr;17(4):433-44. doi: 10.1038/mp.2011.4. Epub 2011 Mar 22.

49.

Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder.

Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML; Bipolar Genome Study (BiGS) Consortium, The Wellcome Trust Case Control Consortium Bipolar Disorder Group, Depaulo JR Jr, Kelsoe JR, Rietschel M, Nöthen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Schulze TG, McMahon FJ, Potash JB, Zandi PP.

Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156B(3):370-8. doi: 10.1002/ajmg.b.31172. Epub 2011 Feb 8. Erratum in: Am J Med Genet B Neuropsychiatr Genet. 2011 Sep;156B(6):749-50.

50.

Design, validation and annotation of transcriptome-wide oligonucleotide probes for the oligochaete annelid Eisenia fetida.

Gong P, Pirooznia M, Guan X, Perkins EJ.

PLoS One. 2010 Dec 8;5(12):e14266. doi: 10.1371/journal.pone.0014266.

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