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Human IgM inhibits the formation of Titan-like cells in Cryptococcus neoformans.

Trevijano-Contador N, Pianalto KM, Nichols CB, Zaragoza O, Alspaugh JA, Pirofski LA.

Infect Immun. 2020 Jan 27. pii: IAI.00046-20. doi: 10.1128/IAI.00046-20. [Epub ahead of print]


The damage response framework and infection prevention: From concept to bedside.

Godbout EJ, Madaline T, Casadevall A, Bearman G, Pirofski LA.

Infect Control Hosp Epidemiol. 2020 Mar;41(3):337-341. doi: 10.1017/ice.2019.354. Epub 2020 Jan 9.


Antimicrobial Therapy in the Context of the Damage-Response Framework: the Prospect of Optimizing Therapy by Reducing Host Damage.

Pirofski LA, Casadevall A.

Antimicrob Agents Chemother. 2020 Jan 27;64(2). pii: e01800-19. doi: 10.1128/AAC.01800-19. Print 2020 Jan 27. Review.


Early Infectious Disease Consultation Is Associated With Lower Mortality in Patients With Severe Sepsis or Septic Shock Who Complete the 3-Hour Sepsis Treatment Bundle.

Madaline T, Wadskier Montagne F, Eisenberg R, Mowrey W, Kaur J, Malik M, Gendlina I, Guo Y, White D, Pirofski LA, Sarwar U.

Open Forum Infect Dis. 2019 Oct 31;6(10):ofz408. doi: 10.1093/ofid/ofz408. eCollection 2019 Oct.


Cryptococcus neoformans infection in Human Immunodeficiency Virus (HIV)-infected and HIV-uninfected patients at an inner-city tertiary care hospital in the Bronx.

Yoon HA, Felsen U, Wang T, Pirofski LA.

Med Mycol. 2019 Jul 25. pii: myz082. doi: 10.1093/mmy/myz082. [Epub ahead of print]


Double-Edged Role of Interleukin 17A in Streptococcus pneumoniae Pathogenesis During Influenza Virus Coinfection.

Ambigapathy G, Schmit T, Mathur RK, Nookala S, Bahri S, Pirofski LA, Khan MN.

J Infect Dis. 2019 Jul 31;220(5):902-912. doi: 10.1093/infdis/jiz193.


Benefits and Costs of Animal Virulence for Microbes.

Casadevall A, Pirofski LA.

mBio. 2019 Jun 4;10(3). pii: e00863-19. doi: 10.1128/mBio.00863-19. Review.


Antibody immunity and natural resistance to cryptococcosis.

Trevijano-Contador N, Pirofski L.

Curr Trop Med Rep. 2019 Jun;6(2):50-54. doi: 10.1007/s40475-019-00174-1. Epub 2019 Apr 4.


Risk factors of laryngeal cryptococcosis: A case report.

Quintero O, Trachuk P, Lerner MZ, Sarungbam J, Pirofski LA, Park SO.

Med Mycol Case Rep. 2019 Apr 27;24:82-85. doi: 10.1016/j.mmcr.2019.04.009. eCollection 2019 Jun.


Is Burnout Infectious? Understanding Drivers of Burnout and Job Satisfaction Among Academic Infectious Diseases Physicians.

Nori P, Bartash R, Cowman K, Dackis M, Pirofski LA.

Open Forum Infect Dis. 2019 Feb 23;6(4):ofz092. doi: 10.1093/ofid/ofz092. eCollection 2019 Apr.


Antibody Responses in HIV-Infected Patients With Advanced Immunosuppression and Asymptomatic Cryptococcal Antigenemia.

Hlupeni A, Nakouzi A, Wang T, Boyd KF, Makadzange TA, Ndhlovu CE, Pirofski LA.

Open Forum Infect Dis. 2018 Dec 11;6(1):ofy333. doi: 10.1093/ofid/ofy333. eCollection 2019 Jan.


The Damage-Response Framework as a Tool for the Physician-Scientist to Understand the Pathogenesis of Infectious Diseases.

Pirofski LA, Casadevall A.

J Infect Dis. 2018 Aug 14;218(suppl_1):S7-S11. doi: 10.1093/infdis/jiy083.


Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome.

Yoon HA, Nakouzi A, Chang CC, Kuniholm MH, Carreño LJ, Wang T, Ndung'u T, Lewin SR, French MA, Pirofski LA.

J Infect Dis. 2019 Jan 9;219(3):420-428. doi: 10.1093/infdis/jiy447.


Fungemia caused by Aureobasidium pullulans in a patient with advanced AIDS: a case report and review of the medical literature.

Mittal J, Szymczak WA, Pirofski LA, Galen BT.

JMM Case Rep. 2018 Mar 14;5(4):e005144. doi: 10.1099/jmmcr.0.005144. eCollection 2018 Apr.


A Capsular Polysaccharide-Specific Antibody Alters Streptococcus pneumoniae Gene Expression during Nasopharyngeal Colonization of Mice.

Doyle CR, Moon JY, Daily JP, Wang T, Pirofski LA.

Infect Immun. 2018 Jun 21;86(7). pii: e00300-18. doi: 10.1128/IAI.00300-18. Print 2018 Jul.


A Therapeutic Vaccine for Recurrent Vulvovaginal Candidiasis.

Casadevall A, Pirofski LA.

Clin Infect Dis. 2018 Jun 1;66(12):1937-1939. doi: 10.1093/cid/ciy188. No abstract available.


Antibody and B Cell Subset Perturbations in Human Immunodeficiency Virus-Uninfected Patients With Cryptococcosis.

Rohatgi S, Nakouzi A, Carreño LJ, Slosar-Cheah M, Kuniholm MH, Wang T, Pappas PG, Pirofski LA.

Open Forum Infect Dis. 2017 Nov 18;5(1):ofx255. doi: 10.1093/ofid/ofx255. eCollection 2018 Jan.


What Is a Host? Attributes of Individual Susceptibility.

Casadevall A, Pirofski LA.

Infect Immun. 2018 Jan 22;86(2). pii: e00636-17. doi: 10.1128/IAI.00636-17. Print 2018 Feb. Review.


Virulence profile: Liise-anne Pirofski.

Pirofski LA.

Virulence. 2018 Jan 1;9(1):275-277. doi: 10.1080/21505594.2017.1382277. Epub 2017 Nov 10. No abstract available.


Life as an Infectious Diseases Physician Scientist: Science is Humanity's Lifeline.

Pirofski LA.

J Infect Dis. 2017 Sep 15;216(suppl_5):S611-S612. doi: 10.1093/infdis/jix270. No abstract available.


Bundle in the Bronx: Impact of a Transition-of-Care Outpatient Parenteral Antibiotic Therapy Bundle on All-Cause 30-Day Hospital Readmissions.

Madaline T, Nori P, Mowrey W, Zukowski E, Gohil S, Sarwar U, Weston G, Urrely R, Palombelli M, Pierino VF, Parsons V, Ehrlich A, Ostrowsky B, Corpuz M, Pirofski LA.

Open Forum Infect Dis. 2017 Jun 29;4(2):ofx097. doi: 10.1093/ofid/ofx097. eCollection 2017 Spring.


Naïve B cells reduce fungal dissemination in Cryptococcus neoformans infected Rag1-/- mice.

Dufaud C, Rivera J, Rohatgi S, Pirofski LA.

Virulence. 2018 Jan 1;9(1):173-184. doi: 10.1080/21505594.2017.1370529. Epub 2017 Oct 4.


Developing Interactive Antimicrobial Stewardship and Infection Prevention Curricula for Diverse Learners: A Tailored Approach.

Nori P, Madaline T, Munjal I, Bhar S, Guo Y, Seo SK, Porrovecchio A, Gancher E, Nosanchuk J, Pirofski LA, Ostrowsky B.

Open Forum Infect Dis. 2017 Jul 20;4(3):ofx117. doi: 10.1093/ofid/ofx117. eCollection 2017 Summer.


Help is on the way: Monoclonal antibody therapy for multi-drug resistant bacteria.

Babb R, Pirofski LA.

Virulence. 2017 Oct 3;8(7):1055-1058. doi: 10.1080/21505594.2017.1306620. Epub 2017 Mar 17. No abstract available.


A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

Schumann B, Hahm HS, Parameswarappa SG, Reppe K, Wahlbrink A, Govindan S, Kaplonek P, Pirofski LA, Witzenrath M, Anish C, Pereira CL, Seeberger PH.

Sci Transl Med. 2017 Mar 8;9(380). pii: eaaf5347. doi: 10.1126/scitranslmed.aaf5347.


A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

Parameswarappa SG, Reppe K, Geissner A, Ménová P, Govindan S, Calow ADJ, Wahlbrink A, Weishaupt MW, Monnanda BP, Bell RL, Pirofski LA, Suttorp N, Sander LE, Witzenrath M, Pereira CL, Anish C, Seeberger PH.

Cell Chem Biol. 2016 Nov 17;23(11):1407-1416. doi: 10.1016/j.chembiol.2016.09.016. Epub 2016 Nov 3.


Protease Inhibitors Do Not Affect Antibody Responses to Pneumococcal Vaccination.

De La Rosa I, Munjal IM, Rodriguez-Barradas M, Yu X, Pirofski LA, Mendoza D.

Clin Vaccine Immunol. 2016 Jun 6;23(6):524-529. doi: 10.1128/CVI.00026-16. Print 2016 Jun.


The Ebola epidemic crystallizes the potential of passive antibody therapy for infectious diseases.

Casadevall A, Pirofski LA.

PLoS Pathog. 2015 Apr 23;11(4):e1004717. doi: 10.1371/journal.ppat.1004717. eCollection 2015 Apr. Review. No abstract available.


What is infectiveness and how is it involved in infection and immunity?

Pirofski LA, Casadevall A.

BMC Immunol. 2015 Mar 26;16:13. doi: 10.1186/s12865-015-0076-1. Review.


Host immunity to Cryptococcus neoformans.

Rohatgi S, Pirofski LA.

Future Microbiol. 2015;10(4):565-81. doi: 10.2217/fmb.14.132. Review.


Quantitative and Qualitative Antibody Responses to Immunization With the Pneumococcal Polysaccharide Vaccine in HIV-Infected Patients After Initiation of Antiretroviral Treatment: Results From a Randomized Clinical Trial.

Rodriguez-Barradas MC, Serpa JA, Munjal I, Mendoza D, Rueda AM, Mushtaq M, Pirofski LA.

J Infect Dis. 2015 Jun 1;211(11):1703-11. doi: 10.1093/infdis/jiu819. Epub 2014 Dec 23.


Microbiology: Ditch the term pathogen.

Casadevall A, Pirofski LA.

Nature. 2014 Dec 11;516(7530):165-6. doi: 10.1038/516165a. No abstract available.


What is a host? Incorporating the microbiota into the damage-response framework.

Casadevall A, Pirofski LA.

Infect Immun. 2015 Jan;83(1):2-7. doi: 10.1128/IAI.02627-14. Epub 2014 Nov 10. Review.


An ahemolytic pneumolysin of Streptococcus pneumoniae manipulates human innate and CD4⁺ T-cell responses and reduces resistance to colonization in mice in a serotype-independent manner.

Khan MN, Coleman JR, Vernatter J, Varshney AK, Dufaud C, Pirofski LA.

J Infect Dis. 2014 Nov 15;210(10):1658-69. doi: 10.1093/infdis/jiu321. Epub 2014 Jun 13.


Characterization of protective extracellular membrane-derived vesicles produced by Streptococcus pneumoniae.

Olaya-Abril A, Prados-Rosales R, McConnell MJ, Martín-Peña R, González-Reyes JA, Jiménez-Munguía I, Gómez-Gascón L, Fernández J, Luque-García JL, García-Lidón C, Estévez H, Pachón J, Obando I, Casadevall A, Pirofski LA, Rodríguez-Ortega MJ.

J Proteomics. 2014 Jun 25;106:46-60. doi: 10.1016/j.jprot.2014.04.023. Epub 2014 Apr 24.


Fc gamma receptor 3A polymorphism and risk for HIV-associated cryptococcal disease.

Rohatgi S, Gohil S, Kuniholm MH, Schultz H, Dufaud C, Armour KL, Badri S, Mailliard RB, Pirofski LA.

mBio. 2013 Aug 27;4(5):e00573-13. doi: 10.1128/mBio.00573-13.


X-linked immunodeficient mice exhibit enhanced susceptibility to Cryptococcus neoformans Infection.

Szymczak WA, Davis MJ, Lundy SK, Dufaud C, Olszewski M, Pirofski LA.

mBio. 2013 Jul 2;4(4). pii: e00265-13. doi: 10.1128/mBio.00265-13.


Current concepts in host-microbe interaction leading to pneumococcal pneumonia.

Vernatter J, Pirofski LA.

Curr Opin Infect Dis. 2013 Jun;26(3):277-83. doi: 10.1097/QCO.0b013e3283608419. Review.


Exserohilum rostratum fungal meningitis associated with methylprednisolone injections.

Casadevall A, Pirofski LA.

Future Microbiol. 2013 Feb;8(2):135-7. doi: 10.2217/fmb.12.138. No abstract available.


Molecular characterization of the early B cell response to pulmonary Cryptococcus neoformans infection.

Rohatgi S, Pirofski LA.

J Immunol. 2012 Dec 15;189(12):5820-30. doi: 10.4049/jimmunol.1201514. Epub 2012 Nov 21.


Tissue-expressed B7x affects the immune response to and outcome of lethal pulmonary infection.

Hofmeyer KA, Scandiuzzi L, Ghosh K, Pirofski LA, Zang X.

J Immunol. 2012 Sep 15;189(6):3054-63. doi: 10.4049/jimmunol.1200701. Epub 2012 Aug 1.


Immunoglobulins in defense, pathogenesis, and therapy of fungal diseases.

Casadevall A, Pirofski LA.

Cell Host Microbe. 2012 May 17;11(5):447-56. doi: 10.1016/j.chom.2012.04.004. Review.


IL-23 dampens the allergic response to Cryptococcus neoformans through IL-17-independent and -dependent mechanisms.

Szymczak WA, Sellers RS, Pirofski LA.

Am J Pathol. 2012 Apr;180(4):1547-59. doi: 10.1016/j.ajpath.2011.12.038. Epub 2012 Feb 16.


CD8+ T cells and risk for bacterial pneumonia and all-cause mortality among HIV-infected women.

Gohil SK, Heo M, Schoenbaum EE, Celentano D, Pirofski LA.

J Acquir Immune Defic Syndr. 2012 Jun 1;60(2):191-8. doi: 10.1097/QAI.0b013e31824d90fe.


Q and A: What is a pathogen? A question that begs the point.

Pirofski LA, Casadevall A.

BMC Biol. 2012 Jan 31;10:6. doi: 10.1186/1741-7007-10-6. No abstract available.


A new synthesis for antibody-mediated immunity.

Casadevall A, Pirofski LA.

Nat Immunol. 2011 Dec 16;13(1):21-8. doi: 10.1038/ni.2184.


Cryptococcus gattii infection in healthy hosts: a sentinel for subclinical immunodeficiency?

Marr KA, Datta K, Pirofski LA, Barnes R.

Clin Infect Dis. 2012 Jan 1;54(1):153-4. doi: 10.1093/cid/cir756. Epub 2011 Nov 10. No abstract available.


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