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Items: 7

1.

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.

Piro AS, Hernandez D, Luoma S, Feeley EM, Finethy R, Yirga A, Frickel EM, Lesser CF, Coers J.

MBio. 2017 Dec 12;8(6). pii: e01979-17. doi: 10.1128/mBio.01979-17.

2.

Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems.

Feeley EM, Pilla-Moffett DM, Zwack EE, Piro AS, Finethy R, Kolb JP, Martinez J, Brodsky IE, Coers J.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1698-E1706. doi: 10.1073/pnas.1615771114. Epub 2017 Feb 13.

3.

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells.

Haldar AK, Piro AS, Finethy R, Espenschied ST, Brown HE, Giebel AM, Frickel EM, Nelson DE, Coers J.

MBio. 2016 Dec 13;7(6). pii: e01417-16. doi: 10.1128/mBio.01417-16.

4.

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins.

Haldar AK, Foltz C, Finethy R, Piro AS, Feeley EM, Pilla-Moffett DM, Komatsu M, Frickel EM, Coers J.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5628-37. doi: 10.1073/pnas.1515966112. Epub 2015 Sep 28.

5.

The E2-like conjugation enzyme Atg3 promotes binding of IRG and Gbp proteins to Chlamydia- and Toxoplasma-containing vacuoles and host resistance.

Haldar AK, Piro AS, Pilla DM, Yamamoto M, Coers J.

PLoS One. 2014 Jan 17;9(1):e86684. doi: 10.1371/journal.pone.0086684. eCollection 2014.

6.

IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins.

Haldar AK, Saka HA, Piro AS, Dunn JD, Henry SC, Taylor GA, Frickel EM, Valdivia RH, Coers J.

PLoS Pathog. 2013;9(6):e1003414. doi: 10.1371/journal.ppat.1003414. Epub 2013 Jun 13.

7.

Small region of Rtf1 protein can substitute for complete Paf1 complex in facilitating global histone H2B ubiquitylation in yeast.

Piro AS, Mayekar MK, Warner MH, Davis CP, Arndt KM.

Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10837-42. doi: 10.1073/pnas.1116994109. Epub 2012 Jun 14.

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