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Items: 31

1.

Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.

Weckbach LT, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, Pick R, Salvermoser M, Czermak T, Pircher J, Sorrelle N, Migliorini M, Strickland DK, Klingel K, Brinkmann V, Abu Abed U, Eriksson U, Massberg S, Brunner S, Walzog B.

J Exp Med. 2019 Feb 4;216(2):350-368. doi: 10.1084/jem.20181102. Epub 2019 Jan 15.

PMID:
30647120
2.

The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis.

Stocker TJ, Pircher J, Skenderi A, Ehrlich A, Eberle C, Megens RTA, Petzold T, Zhang Z, Walzog B, Müller-Taubenberger A, Weber C, Massberg S, Ishikawa-Ankerhold H, Schulz C.

Thromb Haemost. 2018 Dec;118(12):2098-2111. doi: 10.1055/s-0038-1675604. Epub 2018 Nov 19.

PMID:
30453345
3.

Perioptic Cerebrospinal Fluid Dynamics in Idiopathic Intracranial Hypertension.

Pircher A, Montali M, Pircher J, Berberat J, Remonda L, Killer HE.

Front Neurol. 2018 Jun 28;9:506. doi: 10.3389/fneur.2018.00506. eCollection 2018.

4.

LMU Munich: platelet inhibition novel aspects on platelet inhibition and function.

Gross L, Sibbing D, Schulz C, Gärtner F, Pircher J, Massberg S, Petzold T.

Clin Res Cardiol. 2018 Jul 11. doi: 10.1007/s00392-018-1325-0. [Epub ahead of print] Review.

PMID:
29995218
5.

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation.

Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, Stark K, Petzold T, Stocker T, Weckbach LT, Novotny J, Sperandio M, Nieswandt B, Smith A, Mannell H, Walzog B, Horst D, Soehnlein O, Massberg S, Schulz C.

Nat Commun. 2018 Apr 18;9(1):1523. doi: 10.1038/s41467-018-03925-2.

6.

Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal-tension glaucoma.

Pircher A, Montali M, Wostyn P, Pircher J, Berberat J, Remonda L, Killer HE.

Acta Ophthalmol. 2018 Aug;96(5):e562-e569. doi: 10.1111/aos.13647. Epub 2018 Mar 12.

PMID:
29532640
7.

Histological comparison of arterial thrombi in mice and men and the influence of Cl-amidine on thrombus formation.

Novotny J, Chandraratne S, Weinberger T, Philippi V, Stark K, Ehrlich A, Pircher J, Konrad I, Oberdieck P, Titova A, Hoti Q, Schubert I, Legate KR, Urtz N, Lorenz M, Pelisek J, Massberg S, von Brühl ML, Schulz C.

PLoS One. 2018 Jan 2;13(1):e0190728. doi: 10.1371/journal.pone.0190728. eCollection 2018.

8.

Double-stranded DNA induces a prothrombotic phenotype in the vascular endothelium.

Gaitzsch E, Czermak T, Ribeiro A, Heun Y, Bohmer M, Merkle M, Mannell H, Schulz C, Wörnle M, Pircher J.

Sci Rep. 2017 Apr 25;7(1):1112. doi: 10.1038/s41598-017-01148-x.

9.

HIF-1α Dependent Wound Healing Angiogenesis In Vivo Can Be Controlled by Site-Specific Lentiviral Magnetic Targeting of SHP-2.

Heun Y, Pogoda K, Anton M, Pircher J, Pfeifer A, Woernle M, Ribeiro A, Kameritsch P, Mykhaylyk O, Plank C, Kroetz F, Pohl U, Mannell H.

Mol Ther. 2017 Jul 5;25(7):1616-1627. doi: 10.1016/j.ymthe.2017.04.007. Epub 2017 Apr 20.

10.

Maturation of Platelet Function During Murine Fetal Development In Vivo.

Margraf A, Nussbaum C, Rohwedder I, Klapproth S, Kurz ARM, Florian A, Wiebking V, Pircher J, Pruenster M, Immler R, Dietzel S, Kremer L, Kiefer F, Moser M, Flemmer AW, Quackenbush E, von Andrian UH, Sperandio M.

Arterioscler Thromb Vasc Biol. 2017 Jun;37(6):1076-1086. doi: 10.1161/ATVBAHA.116.308464. Epub 2017 Apr 20.

PMID:
28428216
11.

Targeting of Magnetic Nanoparticle-coated Microbubbles to the Vascular Wall Empowers Site-specific Lentiviral Gene Delivery in vivo.

Heun Y, Hildebrand S, Heidsieck A, Gleich B, Anton M, Pircher J, Ribeiro A, Mykhaylyk O, Eberbeck D, Wenzel D, Pfeifer A, Woernle M, Krötz F, Pohl U, Mannell H.

Theranostics. 2017 Jan 1;7(2):295-307. doi: 10.7150/thno.16192. eCollection 2017.

12.

The proteasome regulates collagen-induced platelet aggregation via nuclear-factor-kappa-B (NFĸB) activation.

Grundler K, Rotter R, Tilley S, Pircher J, Czermak T, Yakac M, Gaitzsch E, Massberg S, Krötz F, Sohn HY, Pohl U, Mannell H, Kraemer BF.

Thromb Res. 2016 Dec;148:15-22. doi: 10.1016/j.thromres.2016.10.009. Epub 2016 Oct 13.

PMID:
27768934
13.

Endothelial Dysfunction, and A Prothrombotic, Proinflammatory Phenotype Is Caused by Loss of Mitochondrial Thioredoxin Reductase in Endothelium.

Kirsch J, Schneider H, Pagel JI, Rehberg M, Singer M, Hellfritsch J, Chillo O, Schubert KM, Qiu J, Pogoda K, Kameritsch P, Uhl B, Pircher J, Deindl E, Müller S, Kirchner T, Pohl U, Conrad M, Beck H.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1891-9. doi: 10.1161/ATVBAHA.116.307843. Epub 2016 Jul 7.

PMID:
27386940
14.

Arterial thrombosis in the context of HCV-associated vascular disease can be prevented by protein C.

Blüm P, Pircher J, Merkle M, Czermak T, Ribeiro A, Mannell H, Krötz F, Hennrich A, Spannagl M, Köppel S, Gaitzsch E, Wörnle M.

Cell Mol Immunol. 2017 Dec;14(12):986-996. doi: 10.1038/cmi.2016.10. Epub 2016 Apr 18.

15.

Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.

Mattheij NJ, Braun A, van Kruchten R, Castoldi E, Pircher J, Baaten CC, Wülling M, Kuijpers MJ, Köhler R, Poole AW, Schreiber R, Vortkamp A, Collins PW, Nieswandt B, Kunzelmann K, Cosemans JM, Heemskerk JW.

FASEB J. 2016 Feb;30(2):727-37. doi: 10.1096/fj.15-280446. Epub 2015 Oct 19.

PMID:
26481309
16.

LL37 inhibits the inflammatory endothelial response induced by viral or endogenous DNA.

Merkle M, Pircher J, Mannell H, Krötz F, Blüm P, Czermak T, Gaitzsch E, Schneider C, Köppel S, Ribeiro A, Wörnle M.

J Autoimmun. 2015 Dec;65:19-29. doi: 10.1016/j.jaut.2015.07.015. Epub 2015 Aug 18.

PMID:
26297208
17.

Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes.

Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I.

Circ Res. 2015 Jul 3;117(2):157-65. doi: 10.1161/CIRCRESAHA.117.305784. Epub 2015 May 5.

PMID:
25944670
18.

The tyrosine phosphatase SHP-1 regulates hypoxia inducible factor-1α (HIF-1α) protein levels in endothelial cells under hypoxia.

Alig SK, Stampnik Y, Pircher J, Rotter R, Gaitzsch E, Ribeiro A, Wörnle M, Krötz F, Mannell H.

PLoS One. 2015 Mar 23;10(3):e0121113. doi: 10.1371/journal.pone.0121113. eCollection 2015.

19.

Hepatitis C virus induced endothelial inflammatory response depends on the functional expression of TNFα receptor subtype 2.

Pircher J, Czermak T, Merkle M, Mannell H, Krötz F, Ribeiro A, Vielhauer V, Nadjiri J, Gaitzsch E, Niemeyer M, Porubsky S, Gröne HJ, Wörnle M.

PLoS One. 2014 Nov 24;9(11):e113351. doi: 10.1371/journal.pone.0113351. eCollection 2014.

20.

Label-free determination of hemodynamic parameters in the microcirculaton with third harmonic generation microscopy.

Dietzel S, Pircher J, Nekolla AK, Gull M, Brändli AW, Pohl U, Rehberg M.

PLoS One. 2014 Jun 16;9(6):e99615. doi: 10.1371/journal.pone.0099615. eCollection 2014.

21.

Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice.

Wortmann M, Schneider M, Pircher J, Hellfritsch J, Aichler M, Vegi N, Kölle P, Kuhlencordt P, Walch A, Pohl U, Bornkamm GW, Conrad M, Beck H.

Circ Res. 2013 Aug 2;113(4):408-17. doi: 10.1161/CIRCRESAHA.113.279984. Epub 2013 Jun 14.

PMID:
23770613
22.

The endothelial tyrosine phosphatase SHP-1 plays an important role for vascular haemostasis in TNFα -induced inflammation in vivo.

Koch E, Pircher J, Czermak T, Gaitzsch E, Alig S, Mannell H, Niemeyer M, Krötz F, Wörnle M.

Mediators Inflamm. 2013;2013:279781. doi: 10.1155/2013/279781. Epub 2013 May 9.

23.

Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2.

Pircher J, Merkle M, Wörnle M, Ribeiro A, Czermak T, Stampnik Y, Mannell H, Niemeyer M, Vielhauer V, Krötz F.

Arthritis Res Ther. 2012 Oct 18;14(5):R225. doi: 10.1186/ar4064.

24.

Hydrogen sulfide-releasing aspirin derivative ACS14 exerts strong antithrombotic effects in vitro and in vivo.

Pircher J, Fochler F, Czermak T, Mannell H, Kraemer BF, Wörnle M, Sparatore A, Del Soldato P, Pohl U, Krötz F.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2884-91. doi: 10.1161/ATVBAHA.112.300627. Epub 2012 Sep 27.

PMID:
23023375
25.

Response of VEGF to activation of viral receptors and TNFα in human mesangial cells.

Merkle M, Ribeiro A, Belling F, Mannell H, Krötz F, Pircher J, Wörnle M.

Mol Cell Biochem. 2012 Nov;370(1-2):151-61. doi: 10.1007/s11010-012-1406-8. Epub 2012 Aug 5.

PMID:
22864531
26.

Site directed vascular gene delivery in vivo by ultrasonic destruction of magnetic nanoparticle coated microbubbles.

Mannell H, Pircher J, Fochler F, Stampnik Y, Räthel T, Gleich B, Plank C, Mykhaylyk O, Dahmani C, Wörnle M, Ribeiro A, Pohl U, Krötz F.

Nanomedicine. 2012 Nov;8(8):1309-18. doi: 10.1016/j.nano.2012.03.007. Epub 2012 Apr 2.

PMID:
22480917
27.

TLR3-dependent immune regulatory functions of human mesangial cells.

Merkle M, Ribeiro A, Köppel S, Pircher J, Mannell H, Roeder M, Wörnle M.

Cell Mol Immunol. 2012 Jul;9(4):334-40. doi: 10.1038/cmi.2012.3. Epub 2012 Apr 2.

28.

Targeted endothelial gene delivery by ultrasonic destruction of magnetic microbubbles carrying lentiviral vectors.

Mannell H, Pircher J, Räthel T, Schilberg K, Zimmermann K, Pfeifer A, Mykhaylyk O, Gleich B, Pohl U, Krötz F.

Pharm Res. 2012 May;29(5):1282-94. doi: 10.1007/s11095-012-0678-8. Epub 2012 Jan 25.

PMID:
22274557
29.

Magnetic stents retain nanoparticle-bound antirestenotic drugs transported by lipid microbubbles.

Räthel T, Mannell H, Pircher J, Gleich B, Pohl U, Krötz F.

Pharm Res. 2012 May;29(5):1295-307. doi: 10.1007/s11095-011-0643-y. Epub 2011 Dec 22.

PMID:
22189692
30.

ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression.

Mannell HK, Pircher J, Chaudhry DI, Alig SK, Koch EG, Mettler R, Pohl U, Krötz F.

Cardiovasc Res. 2012 Jan 1;93(1):111-9. doi: 10.1093/cvr/cvr265. Epub 2011 Oct 13.

PMID:
22002459
31.

Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.

Struthmann L, Hellwig N, Pircher J, Sohn HY, Buerkle MA, Klauss V, Mannell H, Pohl U, Krötz F.

J Thromb Haemost. 2009 Oct;7(10):1727-35. doi: 10.1111/j.1538-7836.2009.03582.x. Epub 2009 Aug 19.

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