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Items: 18

1.

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, Frohberger SJ, Sjoberg H, Pionnier N, Murphy E, Archer J, Steven A, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Kwenti TDB, Woods AK, Joseph SB, Hull MV, Xiong W, Kuhen KL, Taylor MJ, Wanji S, Turner JD, Hübner MP, Hoerauf A, Chatterjee AK, Roland J, Tremblay MS, Schultz PG, Sullivan W, Chu XJ, Petrassi HM, McNamara CW.

Sci Transl Med. 2019 May 8;11(491). pii: eaav3523. doi: 10.1126/scitranslmed.aav3523.

PMID:
31068442
2.

Mouse models of Loa loa.

Pionnier NP, Sjoberg H, Chunda VC, Fombad FF, Chounna PW, Njouendou AJ, Metuge HM, Ndzeshang BL, Gandjui NV, Akumtoh DN, Tayong DB, Taylor MJ, Wanji S, Turner JD.

Nat Commun. 2019 Mar 29;10(1):1429. doi: 10.1038/s41467-019-09442-0.

3.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau2086. doi: 10.1126/scitranslmed.aau2086.

PMID:
30867321
4.

Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models.

Sjoberg HT, Pionnier N, Aljayyoussi G, Metuge HM, Njouendou AJ, Chunda VC, Fombad FF, Tayong DB, Gandjui NVT, Akumtoh DN, Chounna PWN, Ndzeshang BL, Lachaud S, Tekle F, Quirynen L, Engelen M, Baeten B, Steven A, Ward SA, Taylor MJ, Wanji S, Turner JD.

PLoS Negl Trop Dis. 2019 Jan 16;13(1):e0006356. doi: 10.1371/journal.pntd.0006356. eCollection 2019 Jan.

5.

The effect of the orientation and the height of periodic sub-micrometric texturing on dropwise condensation.

Pionnier N, Vera J, Contraires E, Benayoun S, Berger R, Valette S.

J Colloid Interface Sci. 2018 Sep 15;526:184-193. doi: 10.1016/j.jcis.2018.04.043. Epub 2018 Apr 30.

PMID:
29729969
6.

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia.

Turner JD, Pionnier N, Furlong-Silva J, Sjoberg H, Cross S, Halliday A, Guimaraes AF, Cook DAN, Steven A, Van Rooijen N, Allen JE, Jenkins SJ, Taylor MJ.

PLoS Pathog. 2018 Mar 16;14(3):e1006949. doi: 10.1371/journal.ppat.1006949. eCollection 2018 Mar.

7.

Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2018 Jan 18;8(1):1384. doi: 10.1038/s41598-018-19723-1.

8.

Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung.

Karadjian G, Fercoq F, Pionnier N, Vallarino-Lhermitte N, Lefoulon E, Nieguitsila A, Specht S, Carlin LM, Martin C.

PLoS Negl Trop Dis. 2017 May 9;11(5):e0005596. doi: 10.1371/journal.pntd.0005596. eCollection 2017 May.

9.

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2017 Mar 16;7(1):210. doi: 10.1038/s41598-017-00322-5. Erratum in: Sci Rep. 2018 Jan 18;8(1):1384.

10.

Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.

Tamarozzi F, Turner JD, Pionnier N, Midgley A, Guimaraes AF, Johnston KL, Edwards SW, Taylor MJ.

Sci Rep. 2016 Oct 18;6:35559. doi: 10.1038/srep35559.

11.

Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae.

Pionnier N, Brotin E, Karadjian G, Hemon P, Gaudin-Nomé F, Vallarino-Lhermitte N, Nieguitsila A, Fercoq F, Aknin ML, Marin-Esteban V, Chollet-Martin S, Schlecht-Louf G, Bachelerie F, Martin C.

PLoS Negl Trop Dis. 2016 Apr 25;10(4):e0004605. doi: 10.1371/journal.pntd.0004605. eCollection 2016 Apr.

12.

Differential effects of alloherpesvirus CyHV-3 and rhabdovirus SVCV on apoptosis in fish cells.

Miest JJ, Adamek M, Pionnier N, Harris S, Matras M, Rakus KŁ, Irnazarow I, Steinhagen D, Hoole D.

Vet Microbiol. 2015 Mar 23;176(1-2):19-31. doi: 10.1016/j.vetmic.2014.12.012. Epub 2014 Dec 23.

PMID:
25596969
13.

C-reactive protein and complement as acute phase reactants in common carp Cyprinus carpio during CyHV-3 infection.

Pionnier N, Adamek M, Miest JJ, Harris SJ, Matras M, Rakus KŁ, Irnazarow I, Hoole D.

Dis Aquat Organ. 2014 Jul 3;109(3):187-99. doi: 10.3354/dao02727.

PMID:
24991845
14.

Feeding common carp Cyprinus carpio with β-glucan supplemented diet stimulates C-reactive protein and complement immune acute phase responses following PAMPs injection.

Pionnier N, Falco A, Miest JJ, Shrive AK, Hoole D.

Fish Shellfish Immunol. 2014 Aug;39(2):285-95. doi: 10.1016/j.fsi.2014.05.008. Epub 2014 May 14.

PMID:
24830773
15.

β-Glucan-supplemented diets increase poly(I:C)-induced gene expression of Mx, possibly via Tlr3-mediated recognition mechanism in common carp (Cyprinus carpio).

Falco A, Miest JJ, Pionnier N, Pietretti D, Forlenza M, Wiegertjes GF, Hoole D.

Fish Shellfish Immunol. 2014 Feb;36(2):494-502. doi: 10.1016/j.fsi.2013.12.005. Epub 2013 Dec 25.

PMID:
24370748
16.

Dietary β-glucan stimulate complement and C-reactive protein acute phase responses in common carp (Cyprinus carpio) during an Aeromonas salmonicida infection.

Pionnier N, Falco A, Miest J, Frost P, Irnazarow I, Shrive A, Hoole D.

Fish Shellfish Immunol. 2013 Mar;34(3):819-31. doi: 10.1016/j.fsi.2012.12.017. Epub 2013 Jan 2.

PMID:
23291104
17.

The influence of dietary β-glucan, PAMP exposure and Aeromonas salmonicida on apoptosis modulation in common carp (Cyprinus carpio).

Miest JJ, Falco A, Pionnier NP, Frost P, Irnazarow I, Williams GT, Hoole D.

Fish Shellfish Immunol. 2012 Oct;33(4):846-56.

PMID:
23198291
18.

Reduced inflammatory response to Aeromonas salmonicida infection in common carp (Cyprinus carpio L.) fed with β-glucan supplements.

Falco A, Frost P, Miest J, Pionnier N, Irnazarow I, Hoole D.

Fish Shellfish Immunol. 2012 Jun;32(6):1051-7. doi: 10.1016/j.fsi.2012.02.028. Epub 2012 Mar 2.

PMID:
22406448

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