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Items: 1 to 50 of 244

1.

Serological markers of extracellular matrix remodeling predict transplant-free survival in primary sclerosing cholangitis.

Nielsen MJ, Thorburn D, Leeming DJ, Hov JR, Nygård S, Moum B, Saffioti F, Gilja OH, Boberg KM, Mazza G, Røsjø H, Pinzani M, Karlsen TH, Karsdal MA, Vesterhus M.

Aliment Pharmacol Ther. 2018 Jul;48(2):179-189. doi: 10.1111/apt.14806. Epub 2018 May 30.

PMID:
29851098
2.

A combined model based on spleen stiffness measurement and Baveno VI criteria to rule out high-risk varices in advanced chronic liver disease.

Colecchia A, Ravaioli F, Marasco G, Colli A, Dajti E, Di Biase AR, Bacchi Reggiani ML, Berzigotti A, Pinzani M, Festi D.

J Hepatol. 2018 Aug;69(2):308-317. doi: 10.1016/j.jhep.2018.04.023. Epub 2018 May 3.

PMID:
29729368
3.

CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis.

Zhao L, Zhang C, Luo X, Wang P, Zhou W, Zhong S, Xie Y, Jiang Y, Yang P, Tang R, Pan Q, Hall AR, Luong TV, Fan J, Varghese Z, Moorhead JF, Pinzani M, Chen Y, Ruan XZ.

J Hepatol. 2018 Apr 27. pii: S0168-8278(18)32014-2. doi: 10.1016/j.jhep.2018.04.006. [Epub ahead of print]

PMID:
29705240
4.

The adenosine monophosphate-activated protein kinase-vacuolar adenosine triphosphatase-pH axis: A key regulator of the profibrogenic phenotype of human hepatic stellate cells.

Marrone G, De Chiara F, Böttcher K, Levi A, Dhar D, Longato L, Mazza G, Zhang Z, Marrali M, Fernández-Iglesias A, Hall A, Luong TV, Viollet B, Pinzani M, Rombouts K.

Hepatology. 2018 Apr 17. doi: 10.1002/hep.30029. [Epub ahead of print]

PMID:
29663481
5.

Liver tissue engineering: From implantable tissue to whole organ engineering.

Mazza G, Al-Akkad W, Rombouts K, Pinzani M.

Hepatol Commun. 2017 Dec 21;2(2):131-141. doi: 10.1002/hep4.1136. eCollection 2018 Feb. Review.

6.

MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation.

Böttcher K, Rombouts K, Saffioti F, Roccarina D, Rosselli M, Hall A, Luong T, Tsochatzis EA, Thorburn D, Pinzani M.

Hepatology. 2018 Jul;68(1):172-186. doi: 10.1002/hep.29782. Epub 2018 May 9.

PMID:
29328499
7.

Fibroblasts and extracellular matrix: Targeting and therapeutic tools in fibrosis and cancer.

Prakash J, Pinzani M.

Adv Drug Deliv Rev. 2017 Nov 1;121:1-2. doi: 10.1016/j.addr.2017.11.008. No abstract available.

PMID:
29191284
8.

Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling.

Sato-Matsubara M, Matsubara T, Daikoku A, Okina Y, Longato L, Rombouts K, Thuy LTT, Adachi J, Tomonaga T, Ikeda K, Yoshizato K, Pinzani M, Kawada N.

J Biol Chem. 2017 Nov 17;292(46):18961-18972. doi: 10.1074/jbc.M117.793794. Epub 2017 Sep 15.

9.

Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J, Eksteen B, Ellinghaus D, Färkkilä M, Festen EAM, Floreani A, Franceschet I, Gotthardt DN, Hirschfield GM, Hoek BV, Holm K, Hohenester S, Hov JR, Imhann F, Invernizzi P, Juran BD, Lenzen H, Lieb W, Liu JZ, Marschall HU, Marzioni M, Melum E, Milkiewicz P, Müller T, Pares A, Rupp C, Rust C, Sandford RN, Schramm C, Schreiber S, Schrumpf E, Silverberg MS, Srivastava B, Sterneck M, Teufel A, Vallier L, Verheij J, Vila AV, Vries B, Zachou K; International PSC Study Group, The UK PSC Consortium, Chapman RW, Manns MP, Pinzani M, Rushbrook SM, Lazaridis KN, Franke A, Anderson CA, Karlsen TH, Ponsioen CY, Weersma RK.

Gut. 2018 Aug;67(8):1517-1524. doi: 10.1136/gutjnl-2016-313598. Epub 2017 Aug 4.

10.

Pathogenesis of biliary fibrosis.

Pinzani M, Luong TV.

Biochim Biophys Acta. 2018 Apr;1864(4 Pt B):1279-1283. doi: 10.1016/j.bbadis.2017.07.026. Epub 2017 Jul 25. Review.

PMID:
28754450
11.

TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis.

Singh HD, Otano I, Rombouts K, Singh KP, Peppa D, Gill US, Böttcher K, Kennedy PTF, Oben J, Pinzani M, Walczak H, Fusai G, Rosenberg WMC, Maini MK.

Sci Rep. 2017 Jul 17;7(1):5514. doi: 10.1038/s41598-017-05845-5.

12.

Rapid production of human liver scaffolds for functional tissue engineering by high shear stress oscillation-decellularization.

Mazza G, Al-Akkad W, Telese A, Longato L, Urbani L, Robinson B, Hall A, Kong K, Frenguelli L, Marrone G, Willacy O, Shaeri M, Burns A, Malago M, Gilbertson J, Rendell N, Moore K, Hughes D, Notingher I, Jell G, Del Rio Hernandez A, De Coppi P, Rombouts K, Pinzani M.

Sci Rep. 2017 Jul 17;7(1):5534. doi: 10.1038/s41598-017-05134-1.

13.

Surrogate endpoints for clinical trials in non-alcoholic steatohepatitis.

Tsochatzis EA, Buzzetti E, Pinzani M.

Lancet Gastroenterol Hepatol. 2017 Aug;2(8):549-550. doi: 10.1016/S2468-1253(17)30184-X. No abstract available.

PMID:
28691682
14.

Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.

Mangione PP, Mazza G, Gilbertson JA, Rendell NB, Canetti D, Giorgetti S, Frenguelli L, Curti M, Rezk T, Raimondi S, Pepys MB, Hawkins PN, Gillmore JD, Taylor GW, Pinzani M, Bellotti V.

J Proteomics. 2017 Aug 8;165:113-118. doi: 10.1016/j.jprot.2017.06.016. Epub 2017 Jun 21.

15.

Pathophysiology of liver fibrosis and the methodological barriers to the development of anti-fibrogenic agents.

Böttcher K, Pinzani M.

Adv Drug Deliv Rev. 2017 Nov 1;121:3-8. doi: 10.1016/j.addr.2017.05.016. Epub 2017 Jun 9. Review.

PMID:
28600202
16.

EASL International Recognition Award Recipient 2017: Professor Kenjiro Wake.

Pinzani M.

J Hepatol. 2017 May;66(5):882-883. doi: 10.1016/j.jhep.2017.01.017. No abstract available.

PMID:
28417887
17.

Non-invasive assessment of liver fibrosis in patients with HBV-related chronic liver disease undergoing antiviral treatment: A preliminary study.

Stasi C, Salomoni E, Arena U, Corti G, Montalto P, Bartalesi F, Marra F, Laffi G, Milani S, Zignego AL, Pinzani M.

Eur J Pharmacol. 2017 Jul 5;806:105-109. doi: 10.1016/j.ejphar.2017.03.063. Epub 2017 Apr 13.

PMID:
28414057
18.

CHK2 overexpression and mislocalisation within mitotic structures enhances chromosomal instability and hepatocellular carcinoma progression.

Carloni V, Lulli M, Madiai S, Mello T, Hall A, Luong TV, Pinzani M, Rombouts K, Galli A.

Gut. 2018 Feb;67(2):348-361. doi: 10.1136/gutjnl-2016-313114. Epub 2017 Mar 30.

PMID:
28360097
19.

Reply to: "The BAVENO VI criteria to identify patients not requiring endoscopic surveillance for esophageal varices - Should We use it?"

Maurice J, Pinzani M, Tsochatzis E, Westbrook RH.

J Hepatol. 2017 Jun;66(6):1332-1333. doi: 10.1016/j.jhep.2017.02.030. Epub 2017 Mar 2. No abstract available.

PMID:
28263781
20.

Bacterial Infections Change Natural History of Cirrhosis Irrespective of Liver Disease Severity.

Dionigi E, Garcovich M, Borzio M, Leandro G, Majumdar A, Tsami A, Arvaniti V, Roccarina D, Pinzani M, Burroughs AK, O'Beirne J, Tsochatzis EA.

Am J Gastroenterol. 2017 Apr;112(4):588-596. doi: 10.1038/ajg.2017.19. Epub 2017 Feb 21.

PMID:
28220780
21.

Transaminase abnormalities and adaptations of the liver lobule manifest at specific cut-offs of steatosis.

Hall A, Covelli C, Manuguerra R, Luong TV, Buzzetti E, Tsochatzis E, Pinzani M, Dhillon AP.

Sci Rep. 2017 Jan 20;7:40977. doi: 10.1038/srep40977.

22.

Reactive gamma-ketoaldehydes as novel activators of hepatic stellate cells in vitro.

Longato L, Andreola F, Davies SS, Roberts JL, Fusai G, Pinzani M, Moore K, Rombouts K.

Free Radic Biol Med. 2017 Jan;102:162-173. doi: 10.1016/j.freeradbiomed.2016.11.036. Epub 2016 Nov 24.

PMID:
27890721
23.

The orphan nuclear receptor COUP-TFII coordinates hypoxia-independent proangiogenic responses in hepatic stellate cells.

Ceni E, Mello T, Polvani S, Vasseur-Cognet M, Tarocchi M, Tempesti S, Cavalieri D, Beltrame L, Marroncini G, Pinzani M, Milani S, Galli A.

J Hepatol. 2017 Apr;66(4):754-764. doi: 10.1016/j.jhep.2016.11.003. Epub 2016 Nov 17.

PMID:
27866920
24.

Validation of the Baveno VI criteria to identify low risk cirrhotic patients not requiring endoscopic surveillance for varices.

Maurice JB, Brodkin E, Arnold F, Navaratnam A, Paine H, Khawar S, Dhar A, Patch D, O'Beirne J, Mookerjee R, Pinzani M, Tsochatzis E, Westbrook RH.

J Hepatol. 2016 Nov;65(5):899-905. doi: 10.1016/j.jhep.2016.06.021. Epub 2016 Jul 5.

PMID:
27388923
25.

Biomarkers of intestinal fibrosis - one step towards clinical trials for stricturing inflammatory bowel disease.

Giuffrida P, Pinzani M, Corazza GR, Di Sabatino A.

United European Gastroenterol J. 2016 Aug;4(4):523-30. doi: 10.1177/2050640616640160. Epub 2016 Mar 21. Review.

26.

Malnutrition and sarcopenia predict post-liver transplantation outcomes independently of the Model for End-stage Liver Disease score.

Kalafateli M, Mantzoukis K, Choi Yau Y, Mohammad AO, Arora S, Rodrigues S, de Vos M, Papadimitriou K, Thorburn D, O'Beirne J, Patch D, Pinzani M, Morgan MY, Agarwal B, Yu D, Burroughs AK, Tsochatzis EA.

J Cachexia Sarcopenia Muscle. 2017 Feb;8(1):113-121. doi: 10.1002/jcsm.12095. Epub 2016 Feb 1.

27.

Development and Regression of Cirrhosis.

Saffioti F, Pinzani M.

Dig Dis. 2016;34(4):374-81. doi: 10.1159/000444550. Epub 2016 May 11.

PMID:
27170391
28.

Optimization of Liver Decellularization Maintains Extracellular Matrix Micro-Architecture and Composition Predisposing to Effective Cell Seeding.

Maghsoudlou P, Georgiades F, Smith H, Milan A, Shangaris P, Urbani L, Loukogeorgakis SP, Lombardi B, Mazza G, Hagen C, Sebire NJ, Turmaine M, Eaton S, Olivo A, Godovac-Zimmermann J, Pinzani M, Gissen P, De Coppi P.

PLoS One. 2016 May 9;11(5):e0155324. doi: 10.1371/journal.pone.0155324. eCollection 2016.

29.

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD).

Buzzetti E, Pinzani M, Tsochatzis EA.

Metabolism. 2016 Aug;65(8):1038-48. doi: 10.1016/j.metabol.2015.12.012. Epub 2016 Jan 4. Review.

PMID:
26823198
30.

Ammonia produces pathological changes in human hepatic stellate cells and is a target for therapy of portal hypertension.

Jalan R, De Chiara F, Balasubramaniyan V, Andreola F, Khetan V, Malago M, Pinzani M, Mookerjee RP, Rombouts K.

J Hepatol. 2016 Apr;64(4):823-33. doi: 10.1016/j.jhep.2015.11.019. Epub 2015 Dec 2.

PMID:
26654994
31.

Amyloid persistence in decellularized liver: biochemical and histopathological characterization.

Mazza G, Simons JP, Al-Shawi R, Ellmerich S, Urbani L, Giorgetti S, Taylor GW, Gilbertson JA, Hall AR, Al-Akkad W, Dhar D, Hawkins PN, De Coppi P, Pinzani M, Bellotti V, Mangione PP.

Amyloid. 2016;23(1):1-7. doi: 10.3109/13506129.2015.1110518. Epub 2015 Dec 8.

32.

Surrogate endpoints for clinical trials in primary sclerosing cholangitis: Review and results from an International PSC Study Group consensus process.

Ponsioen CY, Chapman RW, Chazouillères O, Hirschfield GM, Karlsen TH, Lohse AW, Pinzani M, Schrumpf E, Trauner M, Gores GJ.

Hepatology. 2016 Apr;63(4):1357-67. doi: 10.1002/hep.28256. Epub 2015 Dec 23. Review.

PMID:
26418478
33.

Decoupling competing surface binding kinetics and reconfiguration of receptor footprint for ultrasensitive stress assays.

Patil SB, Vögtli M, Webb B, Mazza G, Pinzani M, Soh YA, McKendry RA, Ndieyira JW.

Nat Nanotechnol. 2015 Oct;10(10):899-907. doi: 10.1038/nnano.2015.174. Epub 2015 Aug 17.

PMID:
26280409
34.

Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation.

Mazza G, Rombouts K, Rennie Hall A, Urbani L, Vinh Luong T, Al-Akkad W, Longato L, Brown D, Maghsoudlou P, Dhillon AP, Fuller B, Davidson B, Moore K, Dhar D, De Coppi P, Malago M, Pinzani M.

Sci Rep. 2015 Aug 7;5:13079. doi: 10.1038/srep13079.

35.

Dysregulated intrahepatic CD4+ T-cell activation drives liver inflammation in ileitis-prone SAMP1/YitFc mice.

Omenetti S, Brogi M, Goodman WA, Croniger CM, Eid S, Huang AY, Laffi G, Roskams T, Cominelli F, Pinzani M, Pizarro TT.

Cell Mol Gastroenterol Hepatol. 2015 Jul 1;1(4):406-419.

36.

Reply to "Points to be considered when using transient elastography for diagnosis of portal hypertension according to the Baveno's VI consensus".

Berzigotti A, Boyer TD, Castéra L, de Franchis R, Genescà J, Pinzani M.

J Hepatol. 2015 Oct;63(4):1049-50. doi: 10.1016/j.jhep.2015.07.012. Epub 2015 Jul 23. No abstract available.

PMID:
26212027
37.

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.

Richards DB, Cookson LM, Berges AC, Barton SV, Lane T, Ritter JM, Fontana M, Moon JC, Pinzani M, Gillmore JD, Hawkins PN, Pepys MB.

N Engl J Med. 2015 Sep 17;373(12):1106-14. doi: 10.1056/NEJMoa1504942. Epub 2015 Jul 15.

38.

Pathophysiology of Liver Fibrosis.

Pinzani M.

Dig Dis. 2015;33(4):492-7. doi: 10.1159/000374096. Epub 2015 Jul 6.

PMID:
26159264
39.

Hepatic regenerative medicine.

Mazza G, De Coppi P, Gissen P, Pinzani M.

J Hepatol. 2015 Aug;63(2):523-4. doi: 10.1016/j.jhep.2015.05.001. Epub 2015 Jun 10. No abstract available.

40.

Liver Fibrosis in the Post-HCV Era.

Pinzani M.

Semin Liver Dis. 2015 May;35(2):157-65. doi: 10.1055/s-0035-1550056. Epub 2015 May 14. Review.

PMID:
25974901
41.

Hepatic fibrosis: Concept to treatment.

Trautwein C, Friedman SL, Schuppan D, Pinzani M.

J Hepatol. 2015 Apr;62(1 Suppl):S15-24. doi: 10.1016/j.jhep.2015.02.039. Review.

42.

Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis.

Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH.

Hepatology. 2015 Jul;62(1):188-97. doi: 10.1002/hep.27825. Epub 2015 Apr 28.

PMID:
25833813
43.

[Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage].

Macias-Barragan J, Caligiuri A, García-Banuelos J, Parola M, Pinzani M, Armendariz-Borunda J.

Rev Med Chil. 2014 Dec;142(12):1553-64. doi: 10.4067/S0034-98872014001200009. Spanish.

44.

Recurrent HCV after liver transplantation-mechanisms, assessment and therapy.

Joshi D, Pinzani M, Carey I, Agarwal K.

Nat Rev Gastroenterol Hepatol. 2014 Dec;11(12):710-21. doi: 10.1038/nrgastro.2014.114. Epub 2014 Jul 15. Review.

PMID:
25023032
45.

Spleen stiffness measurement can predict clinical complications in compensated HCV-related cirrhosis: a prospective study.

Colecchia A, Colli A, Casazza G, Mandolesi D, Schiumerini R, Reggiani LB, Marasco G, Taddia M, Lisotti A, Mazzella G, Di Biase AR, Golfieri R, Pinzani M, Festi D.

J Hepatol. 2014 Jun;60(6):1158-64. doi: 10.1016/j.jhep.2014.02.024. Epub 2014 Mar 6.

PMID:
24607624
46.

The metabolic syndrome and chronic liver disease.

Rosselli M, Lotersztajn S, Vizzutti F, Arena U, Pinzani M, Marra F.

Curr Pharm Des. 2014;20(31):5010-24. Review.

PMID:
24320032
47.

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas.

Govaere O, Komuta M, Berkers J, Spee B, Janssen C, de Luca F, Katoonizadeh A, Wouters J, van Kempen LC, Durnez A, Verslype C, De Kock J, Rogiers V, van Grunsven LA, Topal B, Pirenne J, Vankelecom H, Nevens F, van den Oord J, Pinzani M, Roskams T.

Gut. 2014 Apr;63(4):674-85. doi: 10.1136/gutjnl-2012-304351. Epub 2013 Aug 19.

48.

Longitudinal assessment of liver stiffness in patients undergoing antiviral treatment for hepatitis C.

Stasi C, Arena U, Zignego AL, Corti G, Monti M, Triboli E, Pellegrini E, Renzo S, Leoncini L, Marra F, Laffi G, Milani S, Pinzani M.

Dig Liver Dis. 2013 Oct;45(10):840-3. doi: 10.1016/j.dld.2013.03.023. Epub 2013 May 7.

PMID:
23660078
49.

Beyond scoring: a modern interpretation of disease progression in chronic liver disease.

Rosselli M, MacNaughtan J, Jalan R, Pinzani M.

Gut. 2013 Sep;62(9):1234-41. doi: 10.1136/gutjnl-2012-302826. Epub 2013 May 5. No abstract available.

PMID:
23645629
50.

Neuron-derived orphan receptor 1 promotes proliferation of quiescent hepatocytes.

Vacca M, Murzilli S, Salvatore L, Di Tullio G, D'Orazio A, Lo Sasso G, Graziano G, Pinzani M, Chieppa M, Mariani-Costantini R, Palasciano G, Moschetta A.

Gastroenterology. 2013 Jun;144(7):1518-1529.e3. doi: 10.1053/j.gastro.2013.02.027. Epub 2013 Feb 24.

PMID:
23462179

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